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Identification and definition of asthma-COPD overlap: The CanCOLD study.

Barrecheguren M, Pinto L, Mostafavi-Pour-Manshadi SM, Tan WC, Li PZ, Aaron SD, Benedetti A, Chapman KR, Walker B, Fitzgerald JM, Hernandez P, Maltais F, Marciniuk DD, O'Donnell DE, Sin DD, Bourbeau J; CanCOLD Collaborative Research Group and the Canadian Respiratory Research Network.

Respirology. 2020 Feb 16. doi: 10.1111/resp.13780. [Epub ahead of print]


Inhaler Devices for Delivery of LABA/LAMA Fixed-Dose Combinations in Patients with COPD.

D'Urzo A, Chapman KR, Donohue JF, Kardos P, Maleki-Yazdi MR, Price D.

Pulm Ther. 2019 Jun;5(1):23-41. doi: 10.1007/s41030-019-0090-1. Epub 2019 Mar 13. Review.


Variation at DENND1B and Asthma on the Island of Tristan da Cunha.

Duffy DL, Siminovitch KA, Zamel R, Chapman KR, Martin NG, Zamel N.

Twin Res Hum Genet. 2019 Oct;22(5):277-282. doi: 10.1017/thg.2019.82. Epub 2019 Oct 14.


The effects of marijuana smoking on lung function in older people.

Tan WC, Bourbeau J, Aaron SD, Hogg JC, Maltais F, Hernandez P, Marciniuk DD, Chapman KR, To T, FitzGerald JM, Walker BL, Road J, Zheng L, Zhou G, Yau T, Benedetti A, O'Donnell D, Sin DD; CanCOLD Collaborative Research Group; Members of the CanCOLD Collaborative Research Group not listed as authors:.

Eur Respir J. 2019 Dec 19;54(6). pii: 1900826. doi: 10.1183/13993003.00826-2019. Print 2019 Dec.


The Hidden Story of Nonadherence with Asthma Therapy: For a Few Dollars More?

van Boven JFM, Chapman KR.

J Allergy Clin Immunol Pract. 2019 Sep - Oct;7(7):2307-2308. doi: 10.1016/j.jaip.2019.05.013. No abstract available.


Measurement of sexual disinhibition in dementia: A systematic review.

Chapman KR, Spitznagel MB.

Int J Geriatr Psychiatry. 2019 Dec;34(12):1747-1757. doi: 10.1002/gps.5208. Epub 2019 Sep 11. Review.


Efficacy and safety of inhaled α1-antitrypsin in patients with severe α1-antitrypsin deficiency and frequent exacerbations of COPD.

Stolk J, Tov N, Chapman KR, Fernandez P, MacNee W, Hopkinson NS, Piitulainen E, Seersholm N, Vogelmeier CF, Bals R, McElvaney G, Stockley RA.

Eur Respir J. 2019 Nov 21;54(5). pii: 1900673. doi: 10.1183/13993003.00673-2019. Print 2019 Nov.


Usability of mepolizumab single-use prefilled autoinjector for patient self-administration.

Bernstein D, Pavord ID, Chapman KR, Follows R, Bentley JH, Pouliquen I, Bradford E.

J Asthma. 2019 Jun 28:1-12. doi: 10.1080/02770903.2019.1630641. [Epub ahead of print]


The Role of Sexual Disinhibition to Predict Caregiver Burden and Desire to Institutionalize Among Family Dementia Caregivers.

Chapman KR, Tremont G, Malloy P, Spitznagel MB.

J Geriatr Psychiatry Neurol. 2020 Jan;33(1):42-51. doi: 10.1177/0891988719856688. Epub 2019 Jun 16.


Impaired Sleep Quality in COPD Is Associated With Exacerbations: The CanCOLD Cohort Study.

Shorofsky M, Bourbeau J, Kimoff J, Jen R, Malhotra A, Ayas N, Tan WC, Aaron SD, Sin DD, Road J, Chapman KR, O'Donnell DE, Maltais F, Hernandez P, Walker BL, Marciniuk D, Kaminska M; Canadian Respiratory Research Network; CanCOLD Collaborative Research group.

Chest. 2019 Nov;156(5):852-863. doi: 10.1016/j.chest.2019.04.132. Epub 2019 May 28.


Aclidinium bromide in fixed-dose combination with formoterol fumarate in the management of COPD: an update on the evidence base.

D'Urzo AD, Singh D, Donohue JF, Chapman KR.

Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466619850725. doi: 10.1177/1753466619850725. Review.


Effect of Aclidinium Bromide on Major Cardiovascular Events and Exacerbations in High-Risk Patients With Chronic Obstructive Pulmonary Disease: The ASCENT-COPD Randomized Clinical Trial.

Wise RA, Chapman KR, Scirica BM, Bhatt DL, Daoud SZ, Zetterstrand S, Reisner C, Gil EG.

JAMA. 2019 May 7;321(17):1693-1701. doi: 10.1001/jama.2019.4973.


The clinical benefit of mepolizumab replacing omalizumab in uncontrolled severe eosinophilic asthma.

Chapman KR, Albers FC, Chipps B, Muñoz X, Devouassoux G, Bergna M, Galkin D, Azmi J, Mouneimne D, Price RG, Liu MC.

Allergy. 2019 Sep;74(9):1716-1726. doi: 10.1111/all.13850. Epub 2019 Jul 1.


Identification of Sexual Disinhibition in Dementia by Family Caregivers.

Chapman KR, Tremont G, Malloy P, Spitznagel MB.

Alzheimer Dis Assoc Disord. 2019 Apr-Jun;33(2):154-159. doi: 10.1097/WAD.0000000000000302.


Increasing Awareness of COPD: Two Steps Forward, One Step Back.

Chapman KR.

Chronic Obstr Pulm Dis. 2018 Oct 9;5(4):228-230. doi: 10.15326/jcopdf.5.4.2018.0154. No abstract available.


Real-life effectiveness of indacaterol-glycopyrronium after switching from tiotropium or salmeterol/fluticasone therapy in patients with symptomatic COPD: the POWER study.

Kaplan A, Chapman KR, Anees SM, Mayers I, Rochdi D, Djandji M, Préfontaine D, McIvor A.

Int J Chron Obstruct Pulmon Dis. 2019 Jan 18;14:249-260. doi: 10.2147/COPD.S185485. eCollection 2019.


Psychological distress is related to poor health behaviours in COPD and non-COPD patients: Evidence from the CanCOLD study.

Paine NJ, Bacon SL, Bourbeau J, Tan WC, Lavoie KL; CanCOLD Study Investigators, Aaron SD, Chapman KR, FitzGerald JM, Hernandez P, Marciniuk DD, Maltais F, O'Donnell DE, Sin D, Walker BL; Canadian Respiratory Research Network and teh CanCOLD Collaborative Research Group.

Respir Med. 2019 Jan;146:1-9. doi: 10.1016/j.rmed.2018.11.006. Epub 2018 Nov 15.


An unusual case of alpha-1-antitrypsin deficiency: SZ/Z.

Speevak MD, DeMarco ML, Wiebe NS, Chapman KR.

Clin Biochem. 2019 Feb;64:49-52. doi: 10.1016/j.clinbiochem.2018.12.008. Epub 2018 Dec 21.


Improving Asthma Management: A Tale of Two Countries.

Chapman KR.

J Allergy Clin Immunol Pract. 2018 Nov - Dec;6(6):1926. doi: 10.1016/j.jaip.2018.06.013. No abstract available.


Caregiver burden in the veterinary dermatology client: comparison to healthy controls and relationship to quality of life.

Spitznagel MB, Solc M, Chapman KR, Updegraff J, Albers AL, Carlson MD.

Vet Dermatol. 2019 Feb;30(1):3-e2. doi: 10.1111/vde.12696. Epub 2018 Oct 29.


Reply to Lan and Shi: Different Background, Short Duration, and Inappropriate Participants May Harm Your Conclusion.

Chapman KR, Hurst JR, Fogel RB, Pfister P, Kostikas K, Wedzicha JA.

Am J Respir Crit Care Med. 2019 Feb 1;199(3):390-392. doi: 10.1164/rccm.201809-1776LE. No abstract available.


Nailfold Capillary Morphology in Alzheimer's Disease Dementia.

Cousins CC, Alosco ML, Cousins HC, Chua A, Steinberg EG, Chapman KR, Bing-Canar H, Tripodis Y, Knepper PA, Stern RA, Pasquale LR.

J Alzheimers Dis. 2018;66(2):601-611. doi: 10.3233/JAD-180658.


Safety of biweekly α1-antitrypsin treatment in the RAPID programme.

Greulich T, Chlumsky J, Wencker M, Vit O, Fries M, Chung T, Shebl A, Vogelmeier C, Chapman KR, McElvaney NG; RAPID Trial Group.

Eur Respir J. 2018 Nov 29;52(5). pii: 1800897. doi: 10.1183/13993003.00897-2018. Print 2018 Nov. No abstract available.


Capturing Exacerbations of Chronic Obstructive Pulmonary Disease with EXACT. A Subanalysis of FLAME.

Frent SM, Chapman KR, Larbig M, Mackay A, Fogel R, Gutzwiller FS, Shen S, Patalano F, Banerji D, Kostikas K, Wedzicha JA.

Am J Respir Crit Care Med. 2019 Jan 1;199(1):43-51. doi: 10.1164/rccm.201801-0038OC.


Long-Term Triple Therapy De-escalation to Indacaterol/Glycopyrronium in Patients with Chronic Obstructive Pulmonary Disease (SUNSET): A Randomized, Double-Blind, Triple-Dummy Clinical Trial.

Chapman KR, Hurst JR, Frent SM, Larbig M, Fogel R, Guerin T, Banerji D, Patalano F, Goyal P, Pfister P, Kostikas K, Wedzicha JA.

Am J Respir Crit Care Med. 2018 Aug 1;198(3):329-339. doi: 10.1164/rccm.201803-0405OC.


Lower Aerobic Endurance Linked to History of Depression in Multiple Sclerosis: Preliminary Observations.

Chapman KR, Anderson JR, Calvo D, Pollock BS, Petersen J, Gerhart H, Ridgel A, Spitznagel MB.

J Neurosci Nurs. 2018 Jun;50(3):167-170. doi: 10.1097/JNN.0000000000000360.


Exacerbation heterogeneity in COPD: subgroup analyses from the FLAME study.

Vogelmeier CF, Chapman KR, Miravitlles M, Roche N, Vestbo J, Thach C, Banerji D, Fogel R, Patalano F, Olsson P, Kostikas K, Wedzicha JA.

Int J Chron Obstruct Pulmon Dis. 2018 Apr 10;13:1125-1134. doi: 10.2147/COPD.S160011. eCollection 2018.


Long-Term Evaluation of the Effects of Aclidinium Bromide on Major Adverse Cardiovascular Events and COPD Exacerbations in Patients with Moderate to Very Severe COPD: Rationale and Design of the ASCENT COPD Study.

Wise RA, Chapman KR, Scirica BM, Schoenfeld DA, Bhatt DL, Daoud SZ, Seoane B, Reisner C, Garcia Gil E.

Chronic Obstr Pulm Dis. 2018 Jan 24;5(1):5-15. doi: 10.15326/jcopdf.5.1.2017.0149.


Alpha 1 antitrypsin to treat lung disease in alpha 1 antitrypsin deficiency: recent developments and clinical implications.

Chapman KR, Chorostowska-Wynimko J, Koczulla AR, Ferrarotti I, McElvaney NG.

Int J Chron Obstruct Pulmon Dis. 2018 Jan 31;13:419-432. doi: 10.2147/COPD.S149429. eCollection 2018. Review.


Health Services Burden of Undiagnosed and Overdiagnosed COPD.

Gershon AS, Thiruchelvam D, Chapman KR, Aaron SD, Stanbrook MB, Bourbeau J, Tan W, To T; Canadian Respiratory Research Network.

Chest. 2018 Jun;153(6):1336-1346. doi: 10.1016/j.chest.2018.01.038. Epub 2018 Feb 6.


Asthma biomarkers in the age of biologics.

Kim H, Ellis AK, Fischer D, Noseworthy M, Olivenstein R, Chapman KR, Lee J.

Allergy Asthma Clin Immunol. 2017 Nov 17;13:48. doi: 10.1186/s13223-017-0219-4. eCollection 2017. Review.


Physician perspectives on the burden and management of asthma in six countries: The Global Asthma Physician Survey (GAPS).

Chapman KR, Hinds D, Piazza P, Raherison C, Gibbs M, Greulich T, Gaalswyk K, Lin J, Adachi M, Davis KJ.

BMC Pulm Med. 2017 Nov 23;17(1):153. doi: 10.1186/s12890-017-0492-5.


Self-Management and Clinical Decision Support for Patients With Complex Chronic Conditions Through the Use of Smartphone-Based Telemonitoring: Randomized Controlled Trial Protocol.

Seto E, Ware P, Logan AG, Cafazzo JA, Chapman KR, Segal P, Ross HJ.

JMIR Res Protoc. 2017 Nov 21;6(11):e229. doi: 10.2196/resprot.8367.


Reply to Cooper et al.: The Significance of Eosinophilic Inflammation in Chronic Obstructive Pulmonary Disease.

Roche N, Chapman KR, Vogelmeier CF, Herth FJF, Thach C, Fogel R, Olsson P, Patalano F, Banerji D, Wedzicha JA.

Am J Respir Crit Care Med. 2018 Apr 1;197(7):968-969. doi: 10.1164/rccm.201710-2027LE. No abstract available.


Clinical Utility of Select Neuropsychological Assessment Battery Tests in Predicting Functional Abilities in Dementia.

Ashendorf L, Alosco ML, Bing-Canar H, Chapman KR, Martin B, Chaisson CE, Dixon D, Steinberg EG, Tripodis Y, Kowall NW, Stern RA.

Arch Clin Neuropsychol. 2018 Aug 1;33(5):530-540. doi: 10.1093/arclin/acx100.


Dual Bronchodilation Response by Exacerbation History and Eosinophilia in the FLAME Study.

Papi A, Kostikas K, Wedzicha JA, Vogelmeier CF, Roche N, Shen S, Banerji D, Fogel R, Patalano F, Chapman KR.

Am J Respir Crit Care Med. 2018 May 1;197(9):1223-1226. doi: 10.1164/rccm.201709-1822LE. No abstract available.


Work productivity loss in mild to moderate COPD: lessons learned from the CanCOLD study.

de Sousa Sena R, Ahmed S, Tan WC, Li PZ, Labonté L, Aaron SD, Benedetti A, Chapman KR, Walker B, Fitzgerald JM, Hernandez P, Maltais F, Marciniuk DD, O'Donnell DE, Sin DD, Bourbeau J; CanCOLD Collaborative Research Group and The Canadian Respiratory Research Network.

Eur Respir J. 2017 Sep 12;50(3). pii: 1701154. doi: 10.1183/13993003.01154-2017. Print 2017 Sep. No abstract available.


The Effect of Alpha-1 Proteinase Inhibitor on Biomarkers of Elastin Degradation in Alpha-1 Antitrypsin Deficiency: An Analysis of the RAPID/RAPID Extension Trials.

Ma S, Lin YY, Cantor JO, Chapman KR, Sandhaus RA, Fries M, Edelman JM, McElvaney G, Turino GM.

Chronic Obstr Pulm Dis. 2016 Nov 18;4(1):34-44. doi: 10.15326/jcopdf.4.1.2016.0156.


Quantitative disease progression model of α-1 proteinase inhibitor therapy on computed tomography lung density in patients with α-1 antitrypsin deficiency.

Tortorici MA, Rogers JA, Vit O, Bexon M, Sandhaus RA, Burdon J, Chorostowska-Wynimko J, Thompson P, Stocks J, McElvaney NG, Chapman KR, Edelman JM.

Br J Clin Pharmacol. 2017 Nov;83(11):2386-2397. doi: 10.1111/bcp.13358. Epub 2017 Aug 11.


Reply: What Should Be the Cutoff Value of Blood Eosinophilia as a Predictor of Inhaled Corticosteroid Responsiveness in Patients with Chronic Obstructive Pulmonary Disease?

Roche N, Chapman KR, Vogelmeier CF, Herth FJF, Thach C, Fogel R, Olsson P, Patalano F, Banerji D, Wedzicha JA.

Am J Respir Crit Care Med. 2017 Nov 1;196(9):1230-1231. doi: 10.1164/rccm.201706-1105LE. No abstract available.


Blood Eosinophils and Response to Maintenance Chronic Obstructive Pulmonary Disease Treatment. Data from the FLAME Trial.

Roche N, Chapman KR, Vogelmeier CF, Herth FJF, Thach C, Fogel R, Olsson P, Patalano F, Banerji D, Wedzicha JA.

Am J Respir Crit Care Med. 2017 May 1;195(9):1189-1197. doi: 10.1164/rccm.201701-0193OC.


Long-term efficacy and safety of α1 proteinase inhibitor treatment for emphysema caused by severe α1 antitrypsin deficiency: an open-label extension trial (RAPID-OLE).

McElvaney NG, Burdon J, Holmes M, Glanville A, Wark PA, Thompson PJ, Hernandez P, Chlumsky J, Teschler H, Ficker JH, Seersholm N, Altraja A, Mäkitaro R, Chorostowska-Wynimko J, Sanak M, Stoicescu PI, Piitulainen E, Vit O, Wencker M, Tortorici MA, Fries M, Edelman JM, Chapman KR; RAPID Extension Trial Group.

Lancet Respir Med. 2017 Jan;5(1):51-60. doi: 10.1016/S2213-2600(16)30430-1. Epub 2016 Dec 2. Erratum in: Lancet Respir Med. 2017 Feb;5(2):e13.


Findings on Thoracic Computed Tomography Scans and Respiratory Outcomes in Persons with and without Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study.

Tan WC, Hague CJ, Leipsic J, Bourbeau J, Zheng L, Li PZ, Sin DD, Coxson HO, Kirby M, Hogg JC, Raju R, Road J, O'Donnell DE, Maltais F, Hernandez P, Cowie R, Chapman KR, Marciniuk DD, FitzGerald JM, Aaron SD; Canadian Respiratory Research Network and the CanCOLD Collaborative Research group.

PLoS One. 2016 Nov 18;11(11):e0166745. doi: 10.1371/journal.pone.0166745. eCollection 2016.


Improving the Management of COPD in Women.

Jenkins CR, Chapman KR, Donohue JF, Roche N, Tsiligianni I, Han MK.

Chest. 2017 Mar;151(3):686-696. doi: 10.1016/j.chest.2016.10.031. Epub 2016 Nov 2. Review.


Practice Effects on Story Memory and List Learning Tests in the Neuropsychological Assessment of Older Adults.

Gavett BE, Gurnani AS, Saurman JL, Chapman KR, Steinberg EG, Martin B, Chaisson CE, Mez J, Tripodis Y, Stern RA.

PLoS One. 2016 Oct 6;11(10):e0164492. doi: 10.1371/journal.pone.0164492. eCollection 2016.


The efficacy of aclidinium/formoterol on lung function and symptoms in patients with COPD categorized by symptom status: a pooled analysis.

Miravitlles M, Chapman KR, Chuecos F, Ribera A, Gil EG.

Int J Chron Obstruct Pulmon Dis. 2016 Aug 29;11:2041-53. doi: 10.2147/COPD.S114566. eCollection 2016.


Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II): replicate, phase 3, randomised, double-blind, placebo-controlled trials.

Hanania NA, Korenblat P, Chapman KR, Bateman ED, Kopecky P, Paggiaro P, Yokoyama A, Olsson J, Gray S, Holweg CT, Eisner M, Asare C, Fischer SK, Peng K, Putnam WS, Matthews JG.

Lancet Respir Med. 2016 Oct;4(10):781-796. doi: 10.1016/S2213-2600(16)30265-X. Epub 2016 Sep 5.


The COPD Assessment Test: Can It Discriminate Across COPD Subpopulations?

Gupta N, Pinto L, Benedetti A, Li PZ, Tan WC, Aaron SD, Chapman KR, FitzGerald JM, Hernandez P, Marciniuk DD, Maltais F, O'Donnell DE, Sin D, Walker BL, Bourbeau J; Canadian Respiratory Research Network and the CanCOLD Collaborative Research Group.

Chest. 2016 Nov;150(5):1069-1079. doi: 10.1016/j.chest.2016.06.016. Epub 2016 Jun 27.


Factors associated with undiagnosed and overdiagnosed COPD.

Gershon AS, Hwee J, Chapman KR, Aaron SD, O'Donnell DE, Stanbrook MB, Bourbeau J, Tan W, Su J, Victor JC, To T.

Eur Respir J. 2016 Aug;48(2):561-4. doi: 10.1183/13993003.00458-2016. Epub 2016 Jun 23. No abstract available.


Screening Utility of the King-Devick Test in Mild Cognitive Impairment and Alzheimer Disease Dementia.

Galetta KM, Chapman KR, Essis MD, Alosco ML, Gillard D, Steinberg E, Dixon D, Martin B, Chaisson CE, Kowall NW, Tripodis Y, Balcer LJ, Stern RA.

Alzheimer Dis Assoc Disord. 2017 Apr-Jun;31(2):152-158. doi: 10.1097/WAD.0000000000000157.

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