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Items: 1 to 50 of 188

1.

The onset of pediatric refractory status epilepticus is not distributed uniformly during the day.

Sánchez Fernández I, Gaínza-Lein M, Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Davis Gaillard W, Glauser TA, Goldstein J, Goodkin HP, Guerriero RM, Hecox K, Jackson M, Kapur K, Kelley SA, Kossoff EHW, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ Jr, Sannagowdara K, Stafstrom CE, Tasker RC, Tchapyjnikov D, Topjian AA, Vasquez A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T; Pediatric Status Epilepticus Research Group.

Seizure. 2019 Aug;70:90-96. doi: 10.1016/j.seizure.2019.06.017. Epub 2019 Jun 18.

PMID:
31323566
2.

The epileptic network and cognition: What functional connectivity is teaching us about the childhood epilepsies.

Bear JJ, Chapman KE, Tregellas JR.

Epilepsia. 2019 Aug;60(8):1491-1507. doi: 10.1111/epi.16098. Epub 2019 Jun 27. Review.

PMID:
31247129
3.

Peripheral glucocorticoid signaling in Kawasaki disease.

Sai S, Tamura T, Nagumo K, Chapman KE.

Pediatr Res. 2019 Jun 26. doi: 10.1038/s41390-019-0481-x. [Epub ahead of print] No abstract available.

PMID:
31242500
4.

Electroencephalographic Reporting for Refractory Status Epilepticus.

Sansevere AJ, Arya R, Sánchez Fernández I, Gaillard WD, Tasker RC, Lai YC, Anderson AE, Tchapyjnikov D, Chapman KE, Brenton JN, Carpenter JL, Gaínza-Lein M, Goldstein JL, Goodkin HP, Jackson MC, Kapur K, Mikati MA, Peariso K, Glauser TA, Topjian AA, Wainwright M, Wilfong AA, Williams KL, Loddenkemper T, Abend NS; Pediatric Status Epilepticus Research Group (pSERG).

J Clin Neurophysiol. 2019 Sep;36(5):365-370. doi: 10.1097/WNP.0000000000000595.

PMID:
31166226
5.

Status epilepticus: Will we capture the moment or continue without evidence of efficacy or costs?

Press CA, Chapman KE.

Neurology. 2019 May 14;92(20):931-932. doi: 10.1212/WNL.0000000000007494. No abstract available.

PMID:
31068483
6.

Decreasing case fatality rate following invasive pneumococcal disease, North East England, 2006-2016.

Houseman C, Chapman KE, Manley P, Gorton R, Wilson D, Hughes GJ.

Epidemiol Infect. 2019 Jan;147:e175. doi: 10.1017/S0950268819000657.

7.

Highlights From the Annual Meeting of the American Epilepsy Society 2018.

Jobst BC, Ben-Menachem E, Chapman KE, Fu A, Goldman A, Hirsch LJ, Jehi LE, Kossoff EH, Plueger M, Rho JM, Schevon CA, Shinnar S, Sperling MR, Simeone TA, Wagner JL, Lado F.

Epilepsy Curr. 2019 May-Jun;19(3):152-158. doi: 10.1177/1535759719844486. Epub 2019 May 3.

8.

Antenatal dexamethasone treatment transiently alters diastolic function in the mouse fetal heart.

Agnew EJ, Garcia-Burgos A, Richardson RV, Manos H, Thomson AJW, Sooy K, Just G, Homer NZM, Moran CM, Brunton PJ, Gray GA, Chapman KE.

J Endocrinol. 2019 Jun 1;241(3):279-292. doi: 10.1530/JOE-18-0666.

9.

Corticosteroid receptor balance regulates life and death in cardiomyocytes.

Chapman KE.

Sci Signal. 2019 Apr 16;12(577). pii: eaaw8715. doi: 10.1126/scisignal.aaw8715. Review.

PMID:
30992400
10.

Adrenal hormones mediate disease tolerance in malaria.

Vandermosten L, Pham TT, Knoops S, De Geest C, Lays N, Van der Molen K, Kenyon CJ, Verma M, Chapman KE, Schuit F, De Bosscher K, Opdenakker G, Van den Steen PE.

Nat Commun. 2018 Oct 30;9(1):4525. doi: 10.1038/s41467-018-06986-5.

11.

Reprint of: A three-dimensional in vitro HepG2 cells liver spheroid model for genotoxicity studies.

Shah UK, Mallia JO, Singh N, Chapman KE, Doak SH, Jenkins GJS.

Mutat Res Genet Toxicol Environ Mutagen. 2018 Oct;834:35-41. doi: 10.1016/j.mrgentox.2018.06.020. Epub 2018 Aug 18.

PMID:
30173862
12.

Renal and Blood Pressure Response to a High-Salt Diet in Mice With Reduced Global Expression of the Glucocorticoid Receptor.

Ivy JR, Evans LC, Moorhouse R, Richardson RV, Al-Dujaili EAS, Flatman PW, Kenyon CJ, Chapman KE, Bailey MA.

Front Physiol. 2018 Jul 9;9:848. doi: 10.3389/fphys.2018.00848. eCollection 2018.

13.

Semiautomated Spike Detection Software Persyst 13 Is Noninferior to Human Readers When Calculating the Spike-Wave Index in Electrical Status Epilepticus in Sleep.

Joshi CN, Chapman KE, Bear JJ, Wilson SB, Walleigh DJ, Scheuer ML.

J Clin Neurophysiol. 2018 Sep;35(5):370-374. doi: 10.1097/WNP.0000000000000493.

PMID:
29933261
14.

Baseline and outcome assessment in pediatric status epilepticus.

Jafarpour S, Stredny CM, Piantino J, Chapman KE.

Seizure. 2019 May;68:52-61. doi: 10.1016/j.seizure.2018.04.019. Epub 2018 Apr 27. Review.

PMID:
29747930
15.

Glucocorticoids, antenatal corticosteroid therapy and fetal heart maturation.

Agnew EJ, Ivy JR, Stock SJ, Chapman KE.

J Mol Endocrinol. 2018 Jul;61(1):R61-R73. doi: 10.1530/JME-18-0077. Epub 2018 May 2. Review.

16.

Factors associated with treatment delays in pediatric refractory convulsive status epilepticus.

Sánchez Fernández I, Gaínza-Lein M, Abend NS, Anderson AE, Arya R, Brenton JN, Carpenter JL, Chapman KE, Clark J, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Helseth AR, Jackson MC, Kapur K, Lai YC, McDonough TL, Mikati MA, Nayak A, Peariso K, Riviello JJ Jr, Tasker RC, Tchapyjnikov D, Topjian AA, Wainwright MS, Wilfong A, Williams K, Loddenkemper T; Pediatric Status Epilepticus Research Group (pSERG).

Neurology. 2018 May 8;90(19):e1692-e1701. doi: 10.1212/WNL.0000000000005488. Epub 2018 Apr 11.

17.

Seizure Severity Is Correlated With Severity of Hypoxic-Ischemic Injury in Abusive Head Trauma.

Dingman AL, Stence NV, O'Neill BR, Sillau SH, Chapman KE.

Pediatr Neurol. 2018 May;82:29-35. doi: 10.1016/j.pediatrneurol.2017.12.003. Epub 2017 Dec 12.

PMID:
29625848
18.

Association of Time to Treatment With Short-term Outcomes for Pediatric Patients With Refractory Convulsive Status Epilepticus.

Gaínza-Lein M, Sánchez Fernández I, Jackson M, Abend NS, Arya R, Brenton JN, Carpenter JL, Chapman KE, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Kapur K, Mikati MA, Peariso K, Tasker RC, Tchapyjnikov D, Topjian AA, Wainwright MS, Wilfong A, Williams K, Loddenkemper T; Pediatric Status Epilepticus Research Group.

JAMA Neurol. 2018 Apr 1;75(4):410-418. doi: 10.1001/jamaneurol.2017.4382.

19.

A three-dimensional in vitro HepG2 cells liver spheroid model for genotoxicity studies.

Shah UK, Mallia JO, Singh N, Chapman KE, Doak SH, Jenkins GJS.

Mutat Res Genet Toxicol Environ Mutagen. 2018 Jan;825:51-58. doi: 10.1016/j.mrgentox.2017.12.005. Epub 2017 Dec 15.

PMID:
29307375
20.

11Beta-hydroxysteroid dehydrogenase-1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis.

Zou X, Ramachandran P, Kendall TJ, Pellicoro A, Dora E, Aucott RL, Manwani K, Man TY, Chapman KE, Henderson NC, Forbes SJ, Webster SP, Iredale JP, Walker BR, Michailidou Z.

Hepatology. 2018 Jun;67(6):2167-2181. doi: 10.1002/hep.29734. Epub 2018 Feb 22.

21.

11β-hydroxysteroid dehydrogenase-1 deficiency alters brain energy metabolism in acute systemic inflammation.

Verma M, Kipari TMJ, Zhang Z, Man TY, Forster T, Homer NZM, Seckl JR, Holmes MC, Chapman KE.

Brain Behav Immun. 2018 Mar;69:223-234. doi: 10.1016/j.bbi.2017.11.015. Epub 2017 Nov 21.

22.

A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells.

Wilde EC, Chapman KE, Stannard LM, Seager AL, Brüsehafer K, Shah UK, Tonkin JA, Brown MR, Verma JR, Doherty AT, Johnson GE, Doak SH, Jenkins GJS.

Arch Toxicol. 2018 Feb;92(2):935-951. doi: 10.1007/s00204-017-2102-y. Epub 2017 Nov 6.

23.

11β-hydroxysteroid dehydrogenase type 1 has no effect on survival during experimental malaria but affects parasitemia in a parasite strain-specific manner.

Vandermosten L, De Geest C, Knoops S, Thijs G, Chapman KE, De Bosscher K, Opdenakker G, Van den Steen PE.

Sci Rep. 2017 Oct 23;7(1):13835. doi: 10.1038/s41598-017-14288-x.

24.

Macrophage 11β-HSD-1 deficiency promotes inflammatory angiogenesis.

Zhang Z, Coutinho AE, Man TY, Kipari TMJ, Hadoke PWF, Salter DM, Seckl JR, Chapman KE.

J Endocrinol. 2017 Sep;234(3):291-299. doi: 10.1530/JOE-17-0223. Epub 2017 Jul 4.

25.

Investigation of J-shaped dose-responses induced by exposure to the alkylating agent N-methyl-N-nitrosourea.

Chapman KE, Hoffmann GR, Doak SH, Jenkins GJS.

Mutat Res. 2017 Jul;819:38-46. doi: 10.1016/j.mrgentox.2017.05.002. Epub 2017 May 4.

PMID:
28622829
26.

11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI.

Mylonas KJ, Turner NA, Bageghni SA, Kenyon CJ, White CI, McGregor K, Kimmitt RA, Sulston R, Kelly V, Walker BR, Porter KE, Chapman KE, Gray GA.

J Endocrinol. 2017 Jun;233(3):315-327. doi: 10.1530/JOE-16-0501.

27.

Glucocorticoid receptor alters isovolumetric contraction and restrains cardiac fibrosis.

Richardson RV, Batchen EJ, Thomson AJ, Darroch R, Pan X, Rog-Zielinska EA, Wyrzykowska W, Scullion K, Al-Dujaili EA, Diaz ME, Moran CM, Kenyon CJ, Gray GA, Chapman KE.

J Endocrinol. 2017 Mar;232(3):437-450. doi: 10.1530/JOE-16-0458. Epub 2017 Jan 5.

28.

Refractory status epilepticus in children with and without prior epilepsy or status epilepticus.

Sánchez Fernández I, Jackson MC, Abend NS, Arya R, Brenton JN, Carpenter JL, Chapman KE, Gaillard WD, Gaínza-Lein M, Glauser TA, Goldstein JL, Goodkin HP, Helseth A, Kapur K, McDonough TL, Mikati MA, Peariso K, Riviello J Jr, Tasker RC, Topjian AA, Wainwright MS, Wilfong A, Williams K, Loddenkemper T; pediatric Status Epilepticus Research Group (pSERG).

Neurology. 2017 Jan 24;88(4):386-394. doi: 10.1212/WNL.0000000000003550. Epub 2016 Dec 23.

29.

Increased Invasive Pneumococcal Disease, North East England, UK.

Houseman C, Hughes GJ, Chapman KE, Wilson D, Gorton R.

Emerg Infect Dis. 2017 Jan;23(1):122-126. doi: 10.3201/eid2301.160897.

30.

11β-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to Western diet.

Johnson JS, Opiyo MN, Thomson M, Gharbi K, Seckl JR, Heger A, Chapman KE.

J Endocrinol. 2017 Feb;232(2):273-283. Epub 2016 Nov 24.

31.

EEG Monitoring and Antiepileptic Drugs in Children with Severe TBI.

Ruzas CM, DeWitt PE, Bennett KS, Chapman KE, Harlaar N, Bennett TD.

Neurocrit Care. 2017 Apr;26(2):256-266. doi: 10.1007/s12028-016-0329-8.

32.

Duration of use of oral cannabis extract in a cohort of pediatric epilepsy patients.

Treat L, Chapman KE, Colborn KL, Knupp KG.

Epilepsia. 2017 Jan;58(1):123-127. doi: 10.1111/epi.13617. Epub 2016 Nov 18.

33.

Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate.

Laresgoiti U, Nikolić MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL.

Development. 2016 Oct 15;143(20):3686-3699. Epub 2016 Aug 30.

34.

Genetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm™).

Wills JW, Hondow N, Thomas AD, Chapman KE, Fish D, Maffeis TG, Penny MW, Brown RA, Jenkins GJ, Brown AP, White PA, Doak SH.

Part Fibre Toxicol. 2016 Sep 9;13(1):50. doi: 10.1186/s12989-016-0161-5.

35.

Getting to the heart of intracellular glucocorticoid regeneration: 11β-HSD1 in the myocardium.

Gray GA, White CI, Castellan RF, McSweeney SJ, Chapman KE.

J Mol Endocrinol. 2017 Jan;58(1):R1-R13. Epub 2016 Aug 23. Review.

36.

Reciprocal Regulation of 11β-HSDs May Predict Steroid Sensitivity in Childhood Nephrotic Syndrome.

Sai S, Yamamoto M, Yamaguchi R, Chapman KE, Hongo T.

Pediatrics. 2016 Sep;138(3). pii: e20154011. doi: 10.1542/peds.2015-4011. Epub 2016 Aug 9.

37.

Refractory Status Epilepticus in Children: Intention to Treat With Continuous Infusions of Midazolam and Pentobarbital.

Tasker RC, Goodkin HP, Sánchez Fernández I, Chapman KE, Abend NS, Arya R, Brenton JN, Carpenter JL, Gaillard WD, Glauser TA, Goldstein J, Helseth AR, Jackson MC, Kapur K, Mikati MA, Peariso K, Wainwright MS, Wilfong AA, Williams K, Loddenkemper T; Pediatric Status Epilepticus Research Group.

Pediatr Crit Care Med. 2016 Oct;17(10):968-975.

38.

Antenatal endogenous and exogenous glucocorticoids and their impact on immune ontogeny and long-term immunity.

Solano ME, Holmes MC, Mittelstadt PR, Chapman KE, Tolosa E.

Semin Immunopathol. 2016 Nov;38(6):739-763. Epub 2016 Jul 28. Review.

PMID:
27465226
39.

Rasmussen encephalitis tissue transfer program.

Kruse CA, Pardo CA, Hartman AL, Jallo G, Vining EP, Voros J, Gaillard WD, Liu J, Oluigbo C, Malone S, Bleasel AF, Dexter M, Micati A, Velasco TR, Machado HR, Martino AM, Huang A, Wheatley BM, Grant GA, Granata T, Freri E, Garbelli R, Koh S, Nordli DR, Campos AR, O'Neill B, Handler MH, Chapman KE, Wilfong AA, Curry DJ, Yaun A, Madsen JR, Smyth MD, Mercer D, Bingaman W, Harvey AS, Leventer RJ, Lockhart PJ, Gillies G, Pope K, Giller CA, Park YD, Rojiani AM, Sharma SJ, Jenkins P, Tung S, Huynh MN, Chirwa TW, Cepeda C, Levine MS, Chang JW, Owens GC, Vinters HV, Mathern GW.

Epilepsia. 2016 Jun;57(6):1005-7. doi: 10.1111/epi.13383. No abstract available.

40.

Serotype-specific differences in short- and longer-term mortality following invasive pneumococcal disease.

Hughes GJ, Wright LB, Chapman KE, Wilson D, Gorton R.

Epidemiol Infect. 2016 Sep;144(12):2654-69. doi: 10.1017/S0950268816000856. Epub 2016 May 19.

41.

Pravastatin ameliorates placental vascular defects, fetal growth, and cardiac function in a model of glucocorticoid excess.

Wyrwoll CS, Noble J, Thomson A, Tesic D, Miller MR, Rog-Zielinska EA, Moran CM, Seckl JR, Chapman KE, Holmes MC.

Proc Natl Acad Sci U S A. 2016 May 31;113(22):6265-70. doi: 10.1073/pnas.1520356113. Epub 2016 May 16.

42.

A novel role for the mineralocorticoid receptor in glucocorticoid driven vascular calcification.

Zhu D, Rashdan NA, Chapman KE, Hadoke PW, MacRae VE.

Vascul Pharmacol. 2016 Nov;86:87-93. doi: 10.1016/j.vph.2016.04.005. Epub 2016 May 3.

43.

11β-Hydroxysteroid Dehydrogenase Type 1 Is Expressed in Neutrophils and Restrains an Inflammatory Response in Male Mice.

Coutinho AE, Kipari TM, Zhang Z, Esteves CL, Lucas CD, Gilmour JS, Webster SP, Walker BR, Hughes J, Savill JS, Seckl JR, Rossi AG, Chapman KE.

Endocrinology. 2016 Jul;157(7):2928-36. doi: 10.1210/en.2016-1118. Epub 2016 May 4.

44.

Cardiac GR and MR: From Development to Pathology.

Richardson RV, Batchen EJ, Denvir MA, Gray GA, Chapman KE.

Trends Endocrinol Metab. 2016 Jan;27(1):35-43. doi: 10.1016/j.tem.2015.10.001. Epub 2015 Nov 14. Review.

PMID:
26586027
45.

Decreased Npas4 and Arc mRNA Levels in the Hippocampus of Aged Memory-Impaired Wild-Type But Not Memory Preserved 11β-HSD1 Deficient Mice.

Qiu J, Dunbar DR, Noble J, Cairns C, Carter R, Kelly V, Chapman KE, Seckl JR, Yau JL.

J Neuroendocrinol. 2016 Jan;28(1). doi: 10.1111/jne.12339.

46.

Cardiomyocyte and Vascular Smooth Muscle-Independent 11β-Hydroxysteroid Dehydrogenase 1 Amplifies Infarct Expansion, Hypertrophy, and the Development of Heart Failure After Myocardial Infarction in Male Mice.

White CI, Jansen MA, McGregor K, Mylonas KJ, Richardson RV, Thomson A, Moran CM, Seckl JR, Walker BR, Chapman KE, Gray GA.

Endocrinology. 2016 Jan;157(1):346-57. doi: 10.1210/en.2015-1630. Epub 2015 Oct 14.

47.

Seizing control of epileptic activity can improve outcome.

Chapman KE, Specchio N, Shinnar S, Holmes GL.

Epilepsia. 2015 Oct;56(10):1482-5. doi: 10.1111/epi.13109. Epub 2015 Aug 21. Review.

48.

Early-life perturbations in glucocorticoid activity impacts on the structure, function and molecular composition of the adult zebrafish (Danio rerio) heart.

Wilson KS, Baily J, Tucker CS, Matrone G, Vass S, Moran C, Chapman KE, Mullins JJ, Kenyon C, Hadoke PW, Denvir MA.

Mol Cell Endocrinol. 2015 Oct 15;414:120-31. doi: 10.1016/j.mce.2015.07.025. Epub 2015 Jul 26.

49.

Incidence of seizures on continuous EEG monitoring following traumatic brain injury in children.

O'Neill BR, Handler MH, Tong S, Chapman KE.

J Neurosurg Pediatr. 2015 Aug;16(2):167-76. doi: 10.3171/2014.12.PEDS14263. Epub 2015 May 8.

PMID:
25955809
50.

Time from convulsive status epilepticus onset to anticonvulsant administration in children.

Sánchez Fernández I, Abend NS, Agadi S, An S, Arya R, Brenton JN, Carpenter JL, Chapman KE, Gaillard WD, Glauser TA, Goodkin HP, Kapur K, Mikati MA, Peariso K, Ream M, Riviello J Jr, Tasker RC, Loddenkemper T; Pediatric Status Epilepticus Research Group (pSERG).

Neurology. 2015 Jun 9;84(23):2304-11. doi: 10.1212/WNL.0000000000001673. Epub 2015 May 6.

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