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In support of mitochondrial replacement therapy.

Adashi EY, Caplan AL, Capron A, Chapman AR, Cho M, Clayton EW, Cohen IG, Cook-Deegan R, Faden RR, Friedmann T, Gostin LO, Greely HT, Johnston J, Juengst E, King PA, Knowles LP, Lyerly AD, McGuire AL, Moreno JD, Rothenberg K, Truog RD, Walters L.

Nat Med. 2019 Jun;25(6):870-871. doi: 10.1038/s41591-019-0477-4. No abstract available.


When Going Beyond Gentle Nudges Is Legitimate.

Chapman AR.

Am J Bioeth. 2019 May;19(5):68-69. doi: 10.1080/15265161.2019.1588416. No abstract available.


Incidence and outcomes of unstable angina compared with non-ST-elevation myocardial infarction.

Puelacher C, Gugala M, Adamson PD, Shah A, Chapman AR, Anand A, Sabti Z, Boeddinghaus J, Nestelberger T, Twerenbold R, Wildi K, Badertscher P, Rubini Gimenez M, Shrestha S, Sazgary L, Mueller D, Schumacher L, Kozhuharov N, Flores D, du Fay de Lavallaz J, Miro O, Martín-Sánchez FJ, Morawiec B, Fahrni G, Osswald S, Reichlin T, Mills NL, Mueller C.

Heart. 2019 Apr 24. pii: heartjnl-2018-314305. doi: 10.1136/heartjnl-2018-314305. [Epub ahead of print]


Contemporary point of care cardiac troponin testing in suspected acute coronary syndrome.

Chapman AR, Stewart S, Mills NL.

Heart. 2019 May;105(10):740-741. doi: 10.1136/heartjnl-2018-314306. Epub 2019 Feb 7. No abstract available.


Disease Activity in Mitral Annular Calcification.

Massera D, Trivieri MG, Andrews JPM, Sartori S, Abgral R, Chapman AR, Jenkins WSA, Vesey AT, Doris MK, Pawade TA, Zheng KH, Kizer JR, Newby DE, Dweck MR.

Circ Cardiovasc Imaging. 2019 Feb;12(2):e008513. doi: 10.1161/CIRCIMAGING.118.008513.


Prevalence, Determinants, and Clinical Associations of High-Sensitivity Cardiac Troponin in Patients Attending Emergency Departments.

Lee KK, Noaman A, Vaswani A, Gibbins M, Griffiths M, Chapman AR, Strachan F, Anand A, McAllister DA, Newby DE, Gray AJ, Mills NL, Shah ASV.

Am J Med. 2019 Jan;132(1):110.e8-110.e21. doi: 10.1016/j.amjmed.2018.10.002. Epub 2018 Oct 26.


Novel high-sensitivity cardiac troponin I assay in patients with suspected acute coronary syndrome.

Chapman AR, Fujisawa T, Lee KK, Andrews JP, Anand A, Sandeman D, Ferry AV, Stewart S, Marshall L, Strachan FE, Gray A, Newby DE, Shah ASV, Mills NL.

Heart. 2019 Apr;105(8):616-622. doi: 10.1136/heartjnl-2018-314093. Epub 2018 Nov 15.


High-Sensitivity Cardiac Troponin I and Clinical Risk Scores in Patients With Suspected Acute Coronary Syndrome.

Chapman AR, Hesse K, Andrews J, Ken Lee K, Anand A, Shah ASV, Sandeman D, Ferry AV, Jameson J, Piya S, Stewart S, Marshall L, Strachan FE, Gray A, Newby DE, Mills NL.

Circulation. 2018 Oct 16;138(16):1654-1665. doi: 10.1161/CIRCULATIONAHA.118.036426.


Response To Letter Regarding Article "Long-Term Outcomes in Patients With Type 2 Myocardial Infarction and Myocardial Injury".

Chapman AR, Mills NL.

Circulation. 2018 Sep 11;138(11):1178. doi: 10.1161/CIRCULATIONAHA.118.036021. Epub 2018 Sep 10. No abstract available.


High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial.

Shah ASV, Anand A, Strachan FE, Ferry AV, Lee KK, Chapman AR, Sandeman D, Stables CL, Adamson PD, Andrews JPM, Anwar MS, Hung J, Moss AJ, O'Brien R, Berry C, Findlay I, Walker S, Cruickshank A, Reid A, Gray A, Collinson PO, Apple FS, McAllister DA, Maguire D, Fox KAA, Newby DE, Tuck C, Harkess R, Parker RA, Keerie C, Weir CJ, Mills NL; High-STEACS Investigators.

Lancet. 2018 Sep 15;392(10151):919-928. doi: 10.1016/S0140-6736(18)31923-8. Epub 2018 Aug 28.


Sri Lanka and the possibilities of achieving universal health coverage in a poor country.

Chapman AR, Dharmaratne SD.

Glob Public Health. 2018 Jul 20:1-13. doi: 10.1080/17441692.2018.1501080. [Epub ahead of print]


Ethical Guidelines for Genetic Research on Alcohol Addiction and Its Applications.

Chapman AR, Carter A, Kaplan JM, Morphett K, Hall W.

Kennedy Inst Ethics J. 2018;28(1):1-22. doi: 10.1353/ken.2018.0000.


Long-Term Outcomes in Patients With Type 2 Myocardial Infarction and Myocardial Injury.

Chapman AR, Shah ASV, Lee KK, Anand A, Francis O, Adamson P, McAllister DA, Strachan FE, Newby DE, Mills NL.

Circulation. 2018 Mar 20;137(12):1236-1245. doi: 10.1161/CIRCULATIONAHA.117.031806. Epub 2017 Nov 17.


Association of High-Sensitivity Cardiac Troponin I Concentration With Cardiac Outcomes in Patients With Suspected Acute Coronary Syndrome.

Chapman AR, Lee KK, McAllister DA, Cullen L, Greenslade JH, Parsonage W, Worster A, Kavsak PA, Blankenberg S, Neumann J, Sörensen NA, Westermann D, Buijs MM, Verdel GJE, Pickering JW, Than MP, Twerenbold R, Badertscher P, Sabti Z, Mueller C, Anand A, Adamson P, Strachan FE, Ferry A, Sandeman D, Gray A, Body R, Keevil B, Carlton E, Greaves K, Korley FK, Metkus TS, Sandoval Y, Apple FS, Newby DE, Shah ASV, Mills NL.

JAMA. 2017 Nov 21;318(19):1913-1924. doi: 10.1001/jama.2017.17488. Review. Erratum in: JAMA. 2018 Mar 20;319(11):1168. Soerensen NA [corrected to Sorensen NA].


Patient selection for high sensitivity cardiac troponin testing and diagnosis of myocardial infarction: prospective cohort study.

Shah ASV, Sandoval Y, Noaman A, Sexter A, Vaswani A, Smith SW, Gibbins M, Griffiths M, Chapman AR, Strachan FE, Anand A, Denvir MA, Adamson PD, D'Souza MS, Gray AJ, McAllister DA, Newby DE, Apple FS, Mills NL.

BMJ. 2017 Nov 7;359:j4788. doi: 10.1136/bmj.j4788. Erratum in: BMJ. 2018 Jan 31;360:k495.


A single blood test to rule out acute coronary syndrome.

Chapman AR, Mills NL.

Heart. 2018 Apr;104(8):632-633. doi: 10.1136/heartjnl-2017-312269. Epub 2017 Oct 27. No abstract available.


High-sensitivity cardiac troponin I and risk of heart failure in patients with suspected acute coronary syndrome: a cohort study.

Stelzle D, Shah ASV, Anand A, Strachan FE, Chapman AR, Denvir MA, Mills NL, McAllister DA.

Eur Heart J Qual Care Clin Outcomes. 2018 Jan 1;4(1):36-42. doi: 10.1093/ehjqcco/qcx022.


High-Sensitivity Cardiac Troponin and the Risk Stratification of Patients With Renal Impairment Presenting With Suspected Acute Coronary Syndrome.

Miller-Hodges E, Anand A, Shah ASV, Chapman AR, Gallacher P, Lee KK, Farrah T, Halbesma N, Blackmur JP, Newby DE, Mills NL, Dhaun N.

Circulation. 2018 Jan 30;137(5):425-435. doi: 10.1161/CIRCULATIONAHA.117.030320. Epub 2017 Oct 4.


Duterte's War on Drugs and the Silence of the Addiction Science Community.

Chapman AR, Babor TF.

J Stud Alcohol Drugs. 2017 Jul;78(4):491-493. No abstract available.


High-sensitivity cardiac troponin I assays in the diagnosis of acute myocardial infarction.

Chapman AR, Newby DE, Mills NL.

Heart Asia. 2017 Apr 7;9(1):88-89. doi: 10.1136/heartasia-2016-010867. eCollection 2017. No abstract available.


Comparison of the Efficacy and Safety of Early Rule-Out Pathways for Acute Myocardial Infarction.

Chapman AR, Anand A, Boeddinghaus J, Ferry AV, Sandeman D, Adamson PD, Andrews J, Tan S, Cheng SF, D'Souza M, Orme K, Strachan FE, Nestelberger T, Twerenbold R, Badertscher P, Reichlin T, Gray A, Shah ASV, Mueller C, Newby DE, Mills NL.

Circulation. 2017 Apr 25;135(17):1586-1596. doi: 10.1161/CIRCULATIONAHA.116.025021. Epub 2016 Dec 29.


Appropriate Use of High-Sensitivity Cardiac Troponin Levels in Patients With Suspected Acute Myocardial Infarction.

Chapman AR, Shah AS, Mills NL.

JAMA Cardiol. 2017 Feb 1;2(2):228. doi: 10.1001/jamacardio.2016.4229. No abstract available.


Rapid Rule-Out of Acute Myocardial Injury Using a Single High-Sensitivity Cardiac Troponin I Measurement.

Sandoval Y, Smith SW, Shah AS, Anand A, Chapman AR, Love SA, Schulz K, Cao J, Mills NL, Apple FS.

Clin Chem. 2017 Jan;63(1):369-376. doi: 10.1373/clinchem.2016.264523. Epub 2016 Nov 3.


Assessment and classification of patients with myocardial injury and infarction in clinical practice.

Chapman AR, Adamson PD, Mills NL.

Heart. 2017 Jan 1;103(1):10-18. doi: 10.1136/heartjnl-2016-309530. Epub 2016 Nov 2. Review.


Can human rights standards help protect children and youth from the detrimental impact of alcohol beverage marketing and promotional activities?

Chapman AR.

Addiction. 2017 Jan;112 Suppl 1:117-121. doi: 10.1111/add.13484. Epub 2016 Oct 11. Review.


Refining the Diagnosis of Type 2 Myocardial Infarction.

Chapman AR, Mills NL.

JAMA Cardiol. 2017 Jan 1;2(1):106. doi: 10.1001/jamacardio.2016.3698. No abstract available.


Response: a novel troponin I rule-out value below the upper reference limit for acute myocardial infarction.

Chapman AR, Anand A, Shah AS, Adamson PD, Mills NL.

Heart. 2016 Nov 1;102(21):1772. doi: 10.1136/heartjnl-2016-309958. No abstract available.


A comparison of prognostic significance of strong ion gap (SIG) with other acid-base markers in the critically ill: a cohort study.

Ho KM, Lan NS, Williams TA, Harahsheh Y, Chapman AR, Dobb GJ, Magder S.

J Intensive Care. 2016 Jun 29;4:43. doi: 10.1186/s40560-016-0166-z. eCollection 2016.


Measurement of cardiac troponin for exclusion of myocardial infarction - Authors' reply.

Shah ASV, Anand A, Chapman AR, Newby DE, Mills NL; High-STEACS Investigators.

Lancet. 2016 Jun 4;387(10035):2289-2291. doi: 10.1016/S0140-6736(16)30517-7. No abstract available.


Ethical and practical challenges in providing noninvasive prenatal testing for chromosome abnormalities: an update.

Benn P, Chapman AR.

Curr Opin Obstet Gynecol. 2016 Apr;28(2):119-24. doi: 10.1097/GCO.0000000000000254. Review.


High-sensitivity cardiac troponin I at presentation in patients with suspected acute coronary syndrome: a cohort study.

Shah AS, Anand A, Sandoval Y, Lee KK, Smith SW, Adamson PD, Chapman AR, Langdon T, Sandeman D, Vaswani A, Strachan FE, Ferry A, Stirzaker AG, Reid A, Gray AJ, Collinson PO, McAllister DA, Apple FS, Newby DE, Mills NL; High-STEACS investigators.

Lancet. 2015 Dec 19;386(10012):2481-8. doi: 10.1016/S0140-6736(15)00391-8. Epub 2015 Oct 8.


Fulminant hepatic failure in autoimmune polyendocrine syndrome type-1.

Sinha R, Chapman AR, Reid GT, Hayes PC.

J R Coll Physicians Edinb. 2015;45(2):136-40. doi: 10.4997/JRCPE.2015.210.


The Goals of IPV Survivors Receiving Orders of Protection: An Application of the Empowerment Process Model.

Cattaneo LB, Grossmann J, Chapman AR.

J Interpers Violence. 2016 Oct;31(17):2889-911. doi: 10.1177/0886260515581905. Epub 2015 Apr 27.


Potential costs of B-type natriuretic peptide for the identification of people with heart failure in primary care in Scotland - a pilot study.

Chapman AR, Leslie SJ, Walker SW, Bickler C, Denvir MA.

J R Coll Physicians Edinb. 2015 Mar;45(1):27-32. doi: 10.4997/JRCPE.2015.107.


Single cell transcriptome amplification with MALBAC.

Chapman AR, He Z, Lu S, Yong J, Tan L, Tang F, Xie XS.

PLoS One. 2015 Mar 30;10(3):e0120889. doi: 10.1371/journal.pone.0120889. eCollection 2015.


The social determinants of health: why we should care.

Chapman AR.

Am J Bioeth. 2015;15(3):46-7. doi: 10.1080/15265161.2014.998375. No abstract available.


The effect of prognostic data presentation format on perceived risk among surrogate decision makers of critically ill patients: a randomized comparative trial.

Chapman AR, Litton E, Chamberlain J, Ho KM.

J Crit Care. 2015 Apr;30(2):231-5. doi: 10.1016/j.jcrc.2014.11.005. Epub 2014 Nov 13.


Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet superresolution microscopy.

Zhao ZW, Roy R, Gebhardt JC, Suter DM, Chapman AR, Xie XS.

Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):681-6. doi: 10.1073/pnas.1318496111. Epub 2013 Dec 30.


Three coronary arteries arising from the right coronary cusp with a malignant sub-pulmonary course of the left anterior descending artery.

Chapman AR, Hogg D, Miller J, Padfield GJ.

J Cardiol Cases. 2013 Dec 28;9(3):106-108. doi: 10.1016/j.jccase.2013.11.004. eCollection 2014 Mar.


Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients.

Ni X, Zhuo M, Su Z, Duan J, Gao Y, Wang Z, Zong C, Bai H, Chapman AR, Zhao J, Xu L, An T, Ma Q, Wang Y, Wu M, Sun Y, Wang S, Li Z, Yang X, Yong J, Su XD, Lu Y, Bai F, Xie XS, Wang J.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21083-8. doi: 10.1073/pnas.1320659110. Epub 2013 Dec 9.


Steroid-responsive polyradiculopathy in association with focal segmental glomerulosclerosis.

Chapman AR, Gamble P, Pollock AM, Joss N.

Clin Kidney J. 2013 Dec;6(6):626-9. doi: 10.1093/ckj/sft104. Epub 2013 Aug 26.


Obstetricians and gynecologists' practice and opinions of expanded carrier testing and noninvasive prenatal testing.

Benn P, Chapman AR, Erickson K, Defrancesco MS, Wilkins-Haug L, Egan JF, Schulkin J.

Prenat Diagn. 2014 Feb;34(2):145-52. doi: 10.1002/pd.4272. Epub 2013 Dec 16.


Protecting the right to benefit from science--response.

Chapman AR, Wyndham JM.

Science. 2013 Aug 23;341(6148):841-2. doi: 10.1126/science.341.6148.841-b. No abstract available.


Aspirin desensitization in patients undergoing percutaneous coronary intervention: a survey of current practice.

Chapman AR, Rushworth GF, Leslie SJ.

Cardiol J. 2013;20(2):134-8. doi: 10.5603/CJ.2013.0025.


Single-molecule imaging of transcription factor binding to DNA in live mammalian cells.

Gebhardt JC, Suter DM, Roy R, Zhao ZW, Chapman AR, Basu S, Maniatis T, Xie XS.

Nat Methods. 2013 May;10(5):421-6. doi: 10.1038/nmeth.2411. Epub 2013 Mar 24.


Evaluating ESCROs: perspectives from the University of Connecticut.

Chapman AR.

Am J Bioeth. 2013;13(1):57-8. doi: 10.1080/15265161.2012.747026. No abstract available.


Evaluating the first-in-human clinical trial of a human embryonic stem cell-based therapy.

Chapman AR, Scala CC.

Kennedy Inst Ethics J. 2012 Sep;22(3):243-61.


Noninvasive prenatal testing for early sex identification: a few benefits and many concerns.

Chapman AR, Benn PA.

Perspect Biol Med. 2013 Autumn;56(4):530-47. doi: 10.1353/pbm.2013.0034.


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