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The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma.

Grasso S, Cangelosi D, Chapelle J, Alzona M, Centonze G, Lamolinara A, Salemme V, Angelini C, Morellato A, Saglietto A, Bianchi FT, Cabodi S, Salaroglio IC, Fusella F, Ognibene M, Iezzi M, Pezzolo A, Poli V, Di Cunto F, Eva A, Riganti C, Varesio L, Turco E, Defilippi P.

Cell Death Differ. 2019 Jul 8. doi: 10.1038/s41418-019-0386-6. [Epub ahead of print]


Author Correction: The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries.

Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, di Cantogno LV, Dallaglio K, Castellano I, Amici A, Centonze G, Sharma N, Lunardi S, Cabodi S, Cavallo F, Lamolinara A, Stramucci L, Moiso E, Provero P, Albini A, Sapino A, Staaf J, Di Fiore PP, Bertalot G, Pece S, Tosoni D, Confalonieri S, Iezzi M, Di Stefano P, Turco E, Defilippi P.

Nat Commun. 2018 Mar 30;9:16203. doi: 10.1038/ncomms16203.


The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries.

Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, Verdun di Cantogno L, Dallaglio K, Castellano I, Amici A, Centonze G, Sharma N, Lunardi S, Cabodi S, Cavallo F, Lamolinara A, Stramucci L, Moiso E, Provero P, Albini A, Sapino A, Staaf J, Di Fiore PP, Bertalot G, Pece S, Tosoni D, Confalonieri S, Iezzi M, Di Stefano P, Turco E, Defilippi P.

Nat Commun. 2017 Mar 16;8:14797. doi: 10.1038/ncomms14797. Erratum in: Nat Commun. 2018 Mar 30;9:16203.


Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis.

Principe M, Borgoni S, Cascione M, Chattaragada MS, Ferri-Borgogno S, Capello M, Bulfamante S, Chapelle J, Di Modugno F, Defilippi P, Nisticò P, Cappello P, Riganti C, Leporatti S, Novelli F.

J Hematol Oncol. 2017 Jan 13;10(1):16. doi: 10.1186/s13045-016-0385-8.


Socioeconomic Impact on the Prevalence of Cardiovascular Risk Factors in Wallonia, Belgium: A Population-Based Study.

Streel S, Donneau AF, Hoge A, Majerus S, Kolh P, Chapelle JP, Albert A, Guillaume M.

Biomed Res Int. 2015;2015:580849. doi: 10.1155/2015/580849. Epub 2015 Aug 25.


Vitamin D deficiency is common among adults in Wallonia (Belgium, 51°30' North): findings from the Nutrition, Environment and Cardio-Vascular Health study.

Hoge A, Donneau AF, Streel S, Kolh P, Chapelle JP, Albert A, Cavalier E, Guillaume M.

Nutr Res. 2015 Aug;35(8):716-25. doi: 10.1016/j.nutres.2015.06.005. Epub 2015 Jun 15.


Apolipoprotein-A1 as a damage-associated molecular patterns protein in osteoarthritis: ex vivo and in vitro pro-inflammatory properties.

de Seny D, Cobraiville G, Charlier E, Neuville S, Lutteri L, Le Goff C, Malaise D, Malaise O, Chapelle JP, Relic B, Malaise MG.

PLoS One. 2015 Apr 7;10(4):e0122904. doi: 10.1371/journal.pone.0122904. eCollection 2015.


Identification of protein biomarkers associated with cardiac ischemia by a proteomic approach.

Fillet M, Deroyer C, Cobraiville G, Le Goff C, Cavalier E, Chapelle JP, Marée R, Legrand V, Pierard L, Kolh P, Merville MP.

Biomarkers. 2013 Nov;18(7):614-24. doi: 10.3109/1354750X.2013.838306. Epub 2013 Sep 17.


[Rhupus: when rheumatoid arthritis meets lupus].

Malaise O, Halleux S, von Frenckell C, Lutteri L, Chapelle JP, Malaise MG.

Rev Med Liege. 2012 Sep;67(9):475-84. French.


DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator.

Close P, Gillard M, Ladang A, Jiang Z, Papuga J, Hawkes N, Nguyen L, Chapelle JP, Bouillenne F, Svejstrup J, Fillet M, Chariot A.

J Biol Chem. 2012 Sep 21;287(39):32535-45. Epub 2012 Aug 1.


Procalcitonin usefulness for the initiation of antibiotic treatment in intensive care unit patients.

Layios N, Lambermont B, Canivet JL, Morimont P, Preiser JC, Garweg C, Ledoux D, Frippiat F, Piret S, Giot JB, Wiesen P, Meuris C, Massion P, Leonard P, Nys M, Lancellotti P, Chapelle JP, Damas P.

Crit Care Med. 2012 Aug;40(8):2304-9. doi: 10.1097/CCM.0b013e318251517a.


Multicentre evaluation of a second generation point-of-care assay with an extended range for the determination of N-terminal pro-brain natriuretic peptide.

Jørgensen B, Bertsch T, Bröker HJ, Schäfer M, Chapelle JP, Gadisseur R, Cowie MR, Dikkeschei B, Gurr E, Hayen W, Hafner G, Stiegler Y, Schönherr HR, Strasser RH, Weidtmann B, Folkerts H, Zugck C, Hofmann K, Zerback R.

Clin Lab. 2012;58(5-6):515-25.


[BNP and NT-proBNP: reference values and cutoff limits].

Teixeira J, Guillaume M, Nellessen E, Chapelle JP.

Rev Med Liege. 2012 Jan;67(1):38-43. Review. French.


Analytical evaluation of the new Abbott Architect 25-OH vitamin D assay.

Cavalier E, Carlisi A, Bekaert AC, Rousselle O, Chapelle JP, Souberbielle JC.

Clin Biochem. 2012 Apr;45(6):505-8. doi: 10.1016/j.clinbiochem.2012.01.021. Epub 2012 Feb 1.


Human anti-animal interference in DiaSorin Liaison total 25(OH)-vitamin D assay: towards the end of a strange story?

Cavalier E, Carlisi A, Bekaert AC, Rousselle O, Chapelle JP.

Clin Chim Acta. 2012 Feb 18;413(3-4):527-8. doi: 10.1016/j.cca.2011.11.014. Epub 2011 Nov 21. No abstract available.


New insights on the stability of the parathyroid hormone as assayed by an automated 3rd generation PTH assay.

Cavalier E, Carlisi A, Bekaert AC, Rousselle O, Chapelle JP, Delanaye P.

Clin Chim Acta. 2012 Jan 18;413(1-2):353-4. doi: 10.1016/j.cca.2011.09.034. Epub 2011 Oct 4. No abstract available.


Interpretation of serum PTH concentrations with different kits in dialysis patients according to the KDIGO guidelines: importance of the reference (normal) values.

Cavalier E, Delanaye P, Vranken L, Bekaert AC, Carlisi A, Chapelle JP, Souberbielle JC.

Nephrol Dial Transplant. 2012 May;27(5):1950-6. doi: 10.1093/ndt/gfr535. Epub 2011 Sep 22.


Seasonal variations in vitamin D levels in melanoma patients: a single-centre prospective pilot comparative study.

Failla V, Cavalier E, El Hayderi L, Paurobally D, Chapelle JP, Dezfoulian B, Nikkels AF.

J Eur Acad Dermatol Venereol. 2012 May;26(5):651-3. doi: 10.1111/j.1468-3083.2011.04087.x. Epub 2011 Apr 27.


Lifestyle Behaviours and Plasma Vitamin C and β-Carotene Levels from the ELAN Population (Liège, Belgium).

Pincemail J, Vanbelle S, Degrune F, Cheramy-Bien JP, Charlier C, Chapelle JP, Giet D, Collette G, Albert A, Defraigne JO.

J Nutr Metab. 2011;2011:494370. doi: 10.1155/2011/494370. Epub 2011 Mar 6.


Cross-reactivity of 25-hydroxy vitamin D2 from different commercial immunoassays for 25-hydroxy vitamin D: an evaluation without spiked samples.

Cavalier E, Wallace AM, Carlisi A, Chapelle JP, Delanaye P, Souberbielle JC.

Clin Chem Lab Med. 2011 Mar;49(3):555-8. doi: 10.1515/CCLM.2011.072. Epub 2011 Feb 3. No abstract available.


Human anti-animal antibodies interference in the Siemens Immulite chemiluminescent insulin immuno-assay: about one case.

Cavalier E, Huberty V, Carlisi A, Chapelle JP, Vroonen L, Beckers A.

Clin Chim Acta. 2011 Mar 18;412(7-8):668-9. doi: 10.1016/j.cca.2010.12.035. Epub 2011 Jan 8. No abstract available.


A new tool in the field of in-vitro diagnosis of allergy: preliminary results in the comparison of ImmunoCAP© 250 with the ImmunoCAP© ISAC.

Gadisseur R, Chapelle JP, Cavalier E.

Clin Chem Lab Med. 2011 Feb;49(2):277-80. doi: 10.1515/CCLM.2011.052. Epub 2010 Dec 14.


Analytical validation of the Liaison Calcitonin_II-Gen (DiaSorin).

Cavalier E, Carlisi A, Bekaert AC, Rousselle O, Chapelle JP, Delanaye P.

Clin Chem Lab Med. 2011 Feb;49(2):271-5. doi: 10.1515/CCLM.2011.036. Epub 2010 Nov 18.


Estimate of total salt intake in two regions of Belgium through analysis of sodium in 24-h urine samples.

Vandevijvere S, De Keyzer W, Chapelle JP, Jeanne D, Mouillet G, Huybrechts I, Hulshof P, Van Oyen H.

Eur J Clin Nutr. 2010 Nov;64(11):1260-5. doi: 10.1038/ejcn.2010.148. Epub 2010 Aug 18.


Comparison of three methods for fractionation and enrichment of low molecular weight proteins for SELDI-TOF-MS differential analysis.

De Bock M, de Seny D, Meuwis MA, Servais AC, Minh TQ, Closset J, Chapelle JP, Louis E, Malaise M, Merville MP, Fillet M.

Talanta. 2010 Jun 30;82(1):245-54. doi: 10.1016/j.talanta.2010.04.029. Epub 2010 Apr 22.


BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1.

Keutgens A, Zhang X, Shostak K, Robert I, Olivier S, Vanderplasschen A, Chapelle JP, Viatour P, Merville MP, Bex F, Gothot A, Chariot A.

J Biol Chem. 2010 Aug 13;285(33):25831-40. doi: 10.1074/jbc.M110.112128. Epub 2010 Jun 17.


The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1.

Keutgens A, Shostak K, Close P, Zhang X, Hennuy B, Aussems M, Chapelle JP, Viatour P, Gothot A, Fillet M, Chariot A.

Mol Cell Biol. 2010 Aug;30(16):4006-21. doi: 10.1128/MCB.01600-09. Epub 2010 Jun 14.


The ratio of parathyroid hormone as measured by third- and second-generation assays as a marker for parathyroid carcinoma.

Cavalier E, Daly AF, Betea D, Pruteanu-Apetrii PN, Delanaye P, Stubbs P, Bradwell AR, Chapelle JP, Beckers A.

J Clin Endocrinol Metab. 2010 Aug;95(8):3745-9. doi: 10.1210/jc.2009-2791. Epub 2010 Jun 2.


Multicentre analytical evaluation of a new point-of-care system for the determination of cardiac and thromboembolic markers.

Bertsch T, Chapelle JP, Dempfle CE, Giannitsis E, Schwabs M, Zerback R.

Clin Lab. 2010;56(1-2):37-49.


[Anti-deamidated gliadin peptides antibodies and coeliac disease: state of art and analysis of false-positive results from five assays].

Lutteri L, Sagot C, Chapelle JP.

Ann Biol Clin (Paris). 2010 Mar-Apr;68(2):149-56. doi: 10.1684/abc.2010.0398. French.


The emerging role of lysine acetylation of non-nuclear proteins.

Close P, Creppe C, Gillard M, Ladang A, Chapelle JP, Nguyen L, Chariot A.

Cell Mol Life Sci. 2010 Apr;67(8):1255-64. doi: 10.1007/s00018-009-0252-7. Epub 2010 Jan 16. Review.


[Hymenoptera venom anaphylaxis and in-vitro diagnostic tools: new approaches to manage patients at high risk of a severe reaction].

Gadisseur R, Cataldo D, Collard L, Chapelle JP, Cavalier E.

Rev Med Liege. 2009 Nov;64(11):570-5. French.


Challenges for biomarker discovery in body fluids using SELDI-TOF-MS.

De Bock M, de Seny D, Meuwis MA, Chapelle JP, Louis E, Malaise M, Merville MP, Fillet M.

J Biomed Biotechnol. 2010;2010:906082. doi: 10.1155/2010/906082. Epub 2009 Dec 6. Review.


Multicentre evaluation of the Tosoh HbA1c G8 analyser.

Chapelle JP, Teixeira J, Maisin D, Assink H, Barla G, Stroobants AK, Delzenne B, van den Eshof W.

Clin Chem Lab Med. 2010 Mar;48(3):365-71. doi: 10.1515/CCLM.2010.062.


Analytical validation of serum bone alkaline phosphatase (BAP OSTASE) on Liaison.

Cavalier E, Rozet E, Carlisi A, Bekaert AC, Rousselle O, Hubert P, Chapelle JP, Delanaye P.

Clin Chem Lab Med. 2010;48(1):67-72. doi: 10.1515/CCLM.2010.019.


[Propositions for the standardized expression of HbA 1c results].

Gillery P, Périer C, Bordas-Fonfrède M, Hue G, Chapelle JP, Vexiau P, Vialettes B.

Ann Biol Clin (Paris). 2009 Nov-Dec;67(6):669-71. doi: 10.1684/abc.2009.0391. French.


Estimation of the stability of parathyroid hormone when stored at -80 degrees C for a long period.

Cavalier E, Delanaye P, Hubert P, Krzesinski JM, Chapelle JP, Rozet E.

Clin J Am Soc Nephrol. 2009 Dec;4(12):1988-92. doi: 10.2215/CJN.03970609. Epub 2009 Oct 9.


Measurement uncertainty of 25-OH vitamin D determination with different commercially available kits: impact on the clinical cut offs.

Cavalier E, Rozet E, Gadisseur R, Carlisi A, Monge M, Chapelle JP, Hubert P, Souberbielle JC, Delanaye P.

Osteoporos Int. 2010 Jun;21(6):1047-51. doi: 10.1007/s00198-009-1052-5. Epub 2009 Sep 9.


The proapoptotic C16-ceramide-dependent pathway requires the death-promoting factor Btf in colon adenocarcinoma cells.

Rénert AF, Leprince P, Dieu M, Renaut J, Raes M, Bours V, Chapelle JP, Piette J, Merville MP, Fillet M.

J Proteome Res. 2009 Oct;8(10):4810-22. doi: 10.1021/pr9005316.


[Interest of monoclonal antibodies in biomedical laboratory analysis].

Mistretta VI, Cavalier E, Collette J, Lutteri L, Chapelle JP.

Rev Med Liege. 2009 May-Jun;64(5-6):257-63. French.


[Production of monoclonal antibodies].

Mistretta VI, Cavalier E, Collette J, Chapelle JP.

Rev Med Liege. 2009 May-Jun;64(5-6):248-52. French.


Baseline inflammation is not predictive of periprocedural troponin elevation after elective percutaneous coronary intervention.

Gach O, Louis O, Chapelle JP, Vanbelle S, Pierard LA, Legrand V.

Heart Vessels. 2009 Jul;24(4):267-70. doi: 10.1007/s00380-008-1120-3. Epub 2009 Jul 22.


Estimation of GFR by different creatinine- and cystatin-C-based equations in anorexia nervosa.

Delanaye P, Cavalier E, Radermecker RP, Paquot N, Depas G, Chapelle JP, Scheen AJ, Krzesinski JM.

Clin Nephrol. 2009 May;71(5):482-91.


Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes.

Robert I, Aussems M, Keutgens A, Zhang X, Hennuy B, Viatour P, Vanstraelen G, Merville MP, Chapelle JP, de Leval L, Lambert F, Dejardin E, Gothot A, Chariot A.

Oncogene. 2009 Apr 2;28(13):1626-38. doi: 10.1038/onc.2009.6. Epub 2009 Feb 16.


Human anti-mouse antibodies interferences in Elecsys PTH assay after OKT3 treatment.

Cavalier E, Carlisi A, Chapelle JP, Orfanos P, Uzan M, Falque V, Delanaye P, Hachicha M.

Transplantation. 2009 Feb 15;87(3):451-2. doi: 10.1097/TP.0b013e31819575a1. No abstract available.


Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin.

Creppe C, Malinouskaya L, Volvert ML, Gillard M, Close P, Malaise O, Laguesse S, Cornez I, Rahmouni S, Ormenese S, Belachew S, Malgrange B, Chapelle JP, Siebenlist U, Moonen G, Chariot A, Nguyen L.

Cell. 2009 Feb 6;136(3):551-64. doi: 10.1016/j.cell.2008.11.043. Epub 2009 Jan 29.


An unusual interference in parathormone assay caused by anti-goat IgG: a case report.

Cavalier E, Delanaye P, Carlisi A, Chapelle JP, Collette J.

Clin Chem Lab Med. 2009;47(1):118. doi: 10.1515/CCLM.2009.015. No abstract available.


Vitamin D: current status and perspectives.

Cavalier E, Delanaye P, Chapelle JP, Souberbielle JC.

Clin Chem Lab Med. 2009;47(2):120-7. doi: 10.1515/CCLM.2009.036. Review.


[Plasma calcium in haemodialysis patients: total calcium or ionized calcium? Should we systematically provide a value of total corrected calcium on our protocols?].

Monfort M, Delanaye P, Chapelle JP, Cavalier E.

Ann Biol Clin (Paris). 2008 Sep-Oct;66(5):573-6. doi: 10.1684/abc.2008.0264. French.


Cystatin C or creatinine for detection of stage 3 chronic kidney disease in anorexia nervosa.

Delanaye P, Cavalier E, Radermecker RP, Paquot N, Depas G, Chapelle JP, Scheen AJ, Krzesinski JM.

Nephron Clin Pract. 2008;110(3):c158-63. doi: 10.1159/000166607. Epub 2008 Oct 27.

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