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Susceptible period for cardiovascular complications in patients recovering from sepsis.

Lai CC, Lee MG, Lee WC, Chao CC, Hsu TC, Lee SH, Lee CC; National Taiwan University Hospital Health Data Science Research Group.

CMAJ. 2018 Sep 10;190(36):E1062-E1069. doi: 10.1503/cmaj.171284.


Estimating Life Expectancy From Chinese Medicine Could Improve End-of-Life Care in Terminally Ill Cancer Patients.

Shih YL, Hsu YC, Chiu WH, Chao CC.

Holist Nurs Pract. 2018 Sep/Oct;32(5):247-252. doi: 10.1097/HNP.0000000000000285.


Teaching NeuroImages: CNS hemangioblastomas in von Hippel-Lindau disease with exon 3 deletion.

Chao CC, Tsai YS, Chen LW.

Neurology. 2018 Aug 7;91(6):e601-e602. doi: 10.1212/WNL.0000000000005957. No abstract available.


Thrombospondin 2 promotes tumor metastasis by inducing matrix metalloproteinase-13 production in lung cancer cells.

Liu JF, Lee CW, Tsai MH, Tang CH, Chen PC, Lin LW, Lin CY, Lu CH, Lin YF, Yang SH, Chao CC.

Biochem Pharmacol. 2018 Sep;155:537-546. doi: 10.1016/j.bcp.2018.07.024. Epub 2018 Jul 20.


Gangliosides and Tumors.

Kannagi R, Cai BH, Huang HC, Chao CC, Sakuma K.

Methods Mol Biol. 2018;1804:143-171. doi: 10.1007/978-1-4939-8552-4_6.


Assessment of the clinical efficacy of the heart spectrum blood pressure monitor for diagnosis of atrial fibrillation: An unblinded clinical trial.

Kao WF, Hou SK, Huang CY, Chao CC, Cheng CC, Chen YJ.

PLoS One. 2018 Jun 14;13(6):e0198852. doi: 10.1371/journal.pone.0198852. eCollection 2018.


Microglial control of astrocytes in response to microbial metabolites.

Rothhammer V, Borucki DM, Tjon EC, Takenaka MC, Chao CC, Ardura-Fabregat A, de Lima KA, Gutiérrez-Vázquez C, Hewson P, Staszewski O, Blain M, Healy L, Neziraj T, Borio M, Wheeler M, Dragin LL, Laplaud DA, Antel J, Alvarez JI, Prinz M, Quintana FJ.

Nature. 2018 May;557(7707):724-728. doi: 10.1038/s41586-018-0119-x. Epub 2018 May 16.


Dissemination of Orientia tsutsugamushi, a Causative Agent of Scrub Typhus, and Immunological Responses in the Humanized DRAGA Mouse.

Jiang L, Morris EK, Aguilera-Olvera R, Zhang Z, Chan TC, Shashikumar S, Chao CC, Casares SA, Ching WM.

Front Immunol. 2018 Apr 30;9:816. doi: 10.3389/fimmu.2018.00816. eCollection 2018.


Metabolic characterization of serum from mice challenged with Orientia tsutsugamushi-infected mites.

Chao CC, Ingram BO, Lurchachaiwong W, Ching WM.

New Microbes New Infect. 2018 Feb 22;23:70-76. doi: 10.1016/j.nmni.2018.01.005. eCollection 2018 May.


Targeting HSP60 by subcutaneous injections of jetPEI/HSP60-shRNA destabilizes cytoplasmic survivin and inhibits hepatocellular carcinoma growth.

Huang YH, Lin KH, Yu JS, Wu TJ, Lee WC, Chao CC, Pan TL, Yeh CT.

Mol Carcinog. 2018 Sep;57(9):1087-1101. doi: 10.1002/mc.22827. Epub 2018 May 2.


CD40-mediated HIF-1α expression underlying microangiopathy in diabetic nerve pathology.

Kan HW, Hsieh JH, Chien HF, Lin YH, Yeh TY, Chao CC, Hsieh ST.

Dis Model Mech. 2018 Apr 26;11(4). pii: dmm033647. doi: 10.1242/dmm.033647.


Nationwide Trend of Sepsis: A Comparison Among Octogenarians, Elderly, and Young Adults.

Lee SH, Hsu TC, Lee MG, Chao CC, Lee WC, Lai CC, Lee CC; National Taiwan University Health Economics and Outcome Research Group.

Crit Care Med. 2018 Jun;46(6):926-934. doi: 10.1097/CCM.0000000000003085.


Physiological and pathological characterization of capsaicin-induced reversible nerve degeneration and hyperalgesia.

Chiang H, Chang KC, Kan HW, Wu SW, Tseng MT, Hsueh HW, Lin YH, Chao CC, Hsieh ST.

Eur J Pain. 2018 Jul;22(6):1043-1056. doi: 10.1002/ejp.1189. Epub 2018 Feb 2.


Scrub Typhus Outbreak in Chonburi Province, Central Thailand, 2013.

Rodkvamtook W, Kuttasingkee N, Linsuwanon P, Sudsawat Y, Richards AL, Somsri M, Sangjun N, Chao CC, Davidson S, Wanja E, Gaywee J.

Emerg Infect Dis. 2018 Feb;24(2):361-365. doi: 10.3201/eid2402.171172.


Smartphone transmission of electrocardiography images to reduce time of cardiac catheterization laboratory activation.

Chao CC, Chen YC, Shih CM, Hou SK, Seethala RR, Aisiku IP, Huang CC, Hou PC, Kao WF.

J Chin Med Assoc. 2018 Jun;81(6):505-510. doi: 10.1016/j.jcma.2017.11.009. Epub 2017 Dec 26.


The authors reply.

Lee MG, Chao CC, Hsu TC, Lee CC.

Crit Care Med. 2018 Jan;46(1):e98. doi: 10.1097/CCM.0000000000002787. No abstract available.


Simultaneous realization of high sensing sensitivity and tunability in plasmonic nanostructures arrays.

Chau YC, Wang CK, Shen L, Lim CM, Chiang HP, Chao CC, Huang HJ, Lin CT, Kumara NTRN, Voo NY.

Sci Rep. 2017 Dec 1;7(1):16817. doi: 10.1038/s41598-017-17024-7.


Association of HMGB1 Gene Polymorphisms with Lung Cancer Susceptibility and Clinical Aspects.

Hu W, Liu PY, Yang YC, Chen PC, Su CM, Chao CC, Tang CH.

Int J Med Sci. 2017 Sep 19;14(12):1197-1202. doi: 10.7150/ijms.20933. eCollection 2017.


CCN3 promotes epithelial-mesenchymal transition in prostate cancer via FAK/Akt/HIF-1α-induced twist expression.

Chen PC, Tai HC, Lin TH, Wang SW, Lin CY, Chao CC, Yu HJ, Tsai YC, Lai YW, Lin CW, Tang CH.

Oncotarget. 2017 Aug 10;8(43):74506-74518. doi: 10.18632/oncotarget.20171. eCollection 2017 Sep 26.


CD47-CAR-T Cells Effectively Kill Target Cancer Cells and Block Pancreatic Tumor Growth.

Golubovskaya V, Berahovich R, Zhou H, Xu S, Harto H, Li L, Chao CC, Mao MM, Wu L.

Cancers (Basel). 2017 Oct 21;9(10). pii: E139. doi: 10.3390/cancers9100139.


Molecular Detection and Identification of Rickettsia Species in Ticks (Acari: Ixodidae) Collected From Belize, Central America.

Polsomboon S, Hoel DF, Murphy JR, Linton YM, Motoki M, Robbins RG, Bautista K, Bricen O I, Achee NL, Grieco JP, Ching WM, Chao CC.

J Med Entomol. 2017 Nov 7;54(6):1718-1726. doi: 10.1093/jme/tjx141.


Periostin promotes epithelial-mesenchymal transition via the MAPK/miR-381 axis in lung cancer.

Hu WW, Chen PC, Chen JM, Wu YM, Liu PY, Lu CH, Lin YF, Tang CH, Chao CC.

Oncotarget. 2017 Jul 15;8(37):62248-62260. doi: 10.18632/oncotarget.19273. eCollection 2017 Sep 22.


Plumbagin induces apoptosis in human osteosarcoma through ROS generation, endoplasmic reticulum stress and mitochondrial apoptosis pathway.

Chao CC, Hou SM, Huang CC, Hou CH, Chen PC, Liu JF.

Mol Med Rep. 2017 Oct;16(4):5480-5488. doi: 10.3892/mmr.2017.7222. Epub 2017 Aug 10.


TLR4 and NFκB signaling is critical for taxol resistance in ovarian carcinoma cells.

Sun NK, Huang SL, Chang TC, Chao CC.

J Cell Physiol. 2018 Mar;233(3):2489-2501. doi: 10.1002/jcp.26125. Epub 2017 Aug 30.


Preadmission Use of Calcium Channel Blocking Agents Is Associated With Improved Outcomes in Patients With Sepsis: A Population-Based Propensity Score-Matched Cohort Study.

Lee CC, Lee MG, Lee WC, Lai CC, Chao CC, Hsu WH, Chang SS, Lee M.

Crit Care Med. 2017 Sep;45(9):1500-1508. doi: 10.1097/CCM.0000000000002550.


An ELISA assay using a combination of recombinant proteins from multiple strains of Orientia tsutsugamushi offers an accurate diagnosis for scrub typhus.

Chao CC, Zhang Z, Belinskaya T, Thipmontree W, Tantibhedyangkul W, Silpasakorn S, Wongsawat E, Suputtamongkol Y, Ching WM.

BMC Infect Dis. 2017 Jun 10;17(1):413. doi: 10.1186/s12879-017-2512-8.


Downregulation of miR-199a/b-5p is associated with GCNT2 induction upon epithelial-mesenchymal transition in colon cancer.

Chao CC, Wu PH, Huang HC, Chung HY, Chou YC, Cai BH, Kannagi R.

FEBS Lett. 2017 Jul;591(13):1902-1917. doi: 10.1002/1873-3468.12685. Epub 2017 Jun 10.


Comparative evaluation of 2 rapid immunochromatographic assays for Orientia tsutsugamushi in northeastern Thailand.

Thipmontree W, Chao CC, Suputtamongkol Y, Zhang Z, Ching WM.

Diagn Microbiol Infect Dis. 2017 Jul;88(3):290-291. doi: 10.1016/j.diagmicrobio.2017.04.010. Epub 2017 May 3. No abstract available.


Intraspecies comparative genomics of three strains of Orientia tsutsugamushi with different antibiotic sensitivity.

Liao HM, Chao CC, Lei H, Li B, Tsai S, Hung GC, Ching WM, Lo SC.

Genom Data. 2017 Mar 28;12:84-88. doi: 10.1016/j.gdata.2017.03.012. eCollection 2017 Jun.


PSSMHCpan: a novel PSSM-based software for predicting class I peptide-HLA binding affinity.

Liu G, Li D, Li Z, Qiu S, Li W, Chao CC, Yang N, Li H, Cheng Z, Song X, Cheng L, Zhang X, Wang J, Yang H, Ma K, Hou Y, Li B.

Gigascience. 2017 May 1;6(5):1-11. doi: 10.1093/gigascience/gix017.


Lateral Flow Rapid Test for Accurate and Early Diagnosis of Scrub Typhus: A Febrile Illness of Historically Military Importance in the Pacific Rim.

Chao CC, Zhangm Z, Weissenberger G, Chen HW, Ching WM.

Mil Med. 2017 Mar;182(S1):369-375. doi: 10.7205/MILMED-D-16-00091.


Utility of Loop-mediated Isothermal Amplification Assay, Polymerase Chain Reaction, and ELISA for Diagnosis of Leptospirosis in South Indian Patients.

Sengupta M, Prabhakar AK, Satyendra S, Thambu D, Abraham OC, Balaji V, Chen HW, Chao CC, Ching WM, Prakash JA.

J Glob Infect Dis. 2017 Jan-Mar;9(1):3-7. doi: 10.4103/0974-777X.192967.


Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation.

Rothhammer V, Kenison JE, Tjon E, Takenaka MC, de Lima KA, Borucki DM, Chao CC, Wilz A, Blain M, Healy L, Antel J, Quintana FJ.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2012-2017. doi: 10.1073/pnas.1615413114. Epub 2017 Feb 6.


Attenuated contact heat-evoked potentials associated with sensory and social-emotional symptoms in individuals with autism spectrum disorder.

Chien YL, Wu SW, Chu CP, Hsieh ST, Chao CC, Gau SS.

Sci Rep. 2017 Jan 31;7:36887. doi: 10.1038/srep36887.


Biomarkers of neuropathic pain in skin nerve degeneration neuropathy: contact heat-evoked potentials as a physiological signature.

Wu SW, Wang YC, Hsieh PC, Tseng MT, Chiang MC, Chu CP, Feng FP, Lin YH, Hsieh ST, Chao CC.

Pain. 2017 Mar;158(3):516-525. doi: 10.1097/j.pain.0000000000000791.


Spontaneous metastases in immunocompetent mice harboring a primary tumor driven by oncogene latent membrane protein 1 from Epstein-Barr virus.

Chang PY, Huang Y, Hung TY, Chong KY, Chang YS, Chao CC, Chow KN.

Biomed J. 2016 Aug;39(4):261-271. doi: 10.1016/ Epub 2016 Sep 30.


Inhibition of JNK and prothymosin-alpha sensitizes hepatocellular carcinoma cells to cisplatin.

Lin YT, Liu YC, Chao CC.

Biochem Pharmacol. 2016 Dec 15;122:80-89. doi: 10.1016/j.bcp.2016.10.003. Epub 2016 Oct 14.


Effective gene expression in the rat dorsal root ganglia with a non-viral vector delivered via spinal nerve injection.

Chang MF, Hsieh JH, Chiang H, Kan HW, Huang CM, Chellis L, Lin BS, Miaw SC, Pan CL, Chao CC, Hsieh ST.

Sci Rep. 2016 Oct 17;6:35612. doi: 10.1038/srep35612.


Genomic Sequencing of Orientia tsutsugamushi Strain Karp, an Assembly Comparable to the Genome Size of the Strain Ikeda.

Liao HM, Chao CC, Lei H, Li B, Tsai S, Hung GC, Ching WM, Lo SC.

Genome Announc. 2016 Aug 18;4(4). pii: e00702-16. doi: 10.1128/genomeA.00702-16.


Structural Insights into Substrate Recognition and Catalysis in Outer Membrane Protein B (OmpB) by Protein-lysine Methyltransferases from Rickettsia.

Abeykoon AH, Noinaj N, Choi BE, Wise L, He Y, Chao CC, Wang G, Gucek M, Ching WM, Chock PB, Buchanan SK, Yang DC.

J Biol Chem. 2016 Sep 16;291(38):19962-74. doi: 10.1074/jbc.M116.723460. Epub 2016 Jul 29.


Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.

Rothhammer V, Mascanfroni ID, Bunse L, Takenaka MC, Kenison JE, Mayo L, Chao CC, Patel B, Yan R, Blain M, Alvarez JI, Kébir H, Anandasabapathy N, Izquierdo G, Jung S, Obholzer N, Pochet N, Clish CB, Prinz M, Prat A, Antel J, Quintana FJ.

Nat Med. 2016 Jun;22(6):586-97. doi: 10.1038/nm.4106. Epub 2016 May 9.


Structural characterization of tick cement cones collected from in vivo and artificial membrane blood-fed Lone Star ticks (Amblyomma americanum).

Bullard R, Allen P, Chao CC, Douglas J, Das P, Morgan SE, Ching WM, Karim S.

Ticks Tick Borne Dis. 2016 Jul;7(5):880-892. doi: 10.1016/j.ttbdis.2016.04.006. Epub 2016 Apr 16.


System-wide Analysis of the T Cell Response.

Covacu R, Philip H, Jaronen M, Almeida J, Kenison JE, Darko S, Chao CC, Yaari G, Louzoun Y, Carmel L, Douek DC, Efroni S, Quintana FJ.

Cell Rep. 2016 Mar 22;14(11):2733-44. doi: 10.1016/j.celrep.2016.02.056. Epub 2016 Mar 10.


Pathophysiology of Small-Fiber Sensory System in Parkinson's Disease: Skin Innervation and Contact Heat Evoked Potential.

Lin CH, Chao CC, Wu SW, Hsieh PC, Feng FP, Lin YH, Chen YM, Wu RM, Hsieh ST.

Medicine (Baltimore). 2016 Mar;95(10):e3058. doi: 10.1097/MD.0000000000003058.


Highly Sensitive Loop-Mediated Isothermal Amplification for the Detection of Leptospira.

Chen HW, Weissenberger G, Atkins E, Chao CC, Suputtamongkol Y, Ching WM.

Int J Bacteriol. 2015;2015:147173. doi: 10.1155/2015/147173. Epub 2015 Jan 27.


Induction of neural differentiation in rat C6 glioma cells with taxol.

Chao CC, Kan D, Lo TH, Lu KS, Chien CL.

Brain Behav. 2015 Oct 26;5(12):e00414. doi: 10.1002/brb3.414. eCollection 2015 Dec.


The Temporal Profiles of Changes in Nerve Excitability Indices in Familial Amyloid Polyneuropathy.

Lai HJ, Chiang YW, Yang CC, Hsieh ST, Chao CC, Lee MJ, Kuo CC.

PLoS One. 2015 Nov 3;10(11):e0141935. doi: 10.1371/journal.pone.0141935. eCollection 2015.


Quality of life in polyneuropathy: association with biomarkers of small fiber impairment.

Lin MT, Lee LJ, Chao CC, Hsieh ST.

Health Qual Life Outcomes. 2015 Oct 15;13:169. doi: 10.1186/s12955-015-0363-9.

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