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Items: 1 to 50 of 60

1.

Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples.

Edwards V DK, Sweeney DT, Ho H, Eide CA, Rofelty A, Agarwal A, Liu SQ, Danilov AV, Lee P, Chantry D, McWeeney SK, Druker BJ, Tyner JW, Spurgeon SE, Loriaux MM.

Oncotarget. 2018 May 15;9(37):24576-24589. doi: 10.18632/oncotarget.25191. eCollection 2018 May 15.

2.

Pexmetinib: A Novel Dual Inhibitor of Tie2 and p38 MAPK with Efficacy in Preclinical Models of Myelodysplastic Syndromes and Acute Myeloid Leukemia.

Bachegowda L, Morrone K, Winski SL, Mantzaris I, Bartenstein M, Ramachandra N, Giricz O, Sukrithan V, Nwankwo G, Shahnaz S, Bhagat T, Bhattacharyya S, Assal A, Shastri A, Gordon-Mitchell S, Pellagatti A, Boultwood J, Schinke C, Yu Y, Guha C, Rizzi J, Garrus J, Brown S, Wollenberg L, Hogeland G, Wright D, Munson M, Rodriguez M, Gross S, Chantry D, Zou Y, Platanias L, Burgess LE, Pradhan K, Steidl U, Verma A.

Cancer Res. 2016 Aug 15;76(16):4841-4849. doi: 10.1158/0008-5472.CAN-15-3062. Epub 2016 Jun 10.

3.

Potent and highly selective benzimidazole inhibitors of PI3-kinase delta.

Murray JM, Sweeney ZK, Chan BK, Balazs M, Bradley E, Castanedo G, Chabot C, Chantry D, Flagella M, Goldstein DM, Kondru R, Lesnick J, Li J, Lucas MC, Nonomiya J, Pang J, Price S, Salphati L, Safina B, Savy PP, Seward EM, Ultsch M, Sutherlin DP.

J Med Chem. 2012 Sep 13;55(17):7686-95. doi: 10.1021/jm300717c. Epub 2012 Aug 21.

PMID:
22877085
4.

Potent and selective inhibitors of PI3Kδ: obtaining isoform selectivity from the affinity pocket and tryptophan shelf.

Sutherlin DP, Baker S, Bisconte A, Blaney PM, Brown A, Chan BK, Chantry D, Castanedo G, DePledge P, Goldsmith P, Goldstein DM, Hancox T, Kaur J, Knowles D, Kondru R, Lesnick J, Lucas MC, Lewis C, Murray J, Nadin AJ, Nonomiya J, Pang J, Pegg N, Price S, Reif K, Safina BS, Salphati L, Staben S, Seward EM, Shuttleworth S, Sohal S, Sweeney ZK, Ultsch M, Waszkowycz B, Wei B.

Bioorg Med Chem Lett. 2012 Jul 1;22(13):4296-302. doi: 10.1016/j.bmcl.2012.05.027. Epub 2012 May 17.

PMID:
22672799
5.

Inflammation Research Association: 12th international conference.

Chantry D, Burgess LE.

Expert Opin Emerg Drugs. 2005 Feb;10(1):219-24.

PMID:
15757413
6.

Racemic and chiral lactams as potent, selective and functionally active CCR4 antagonists.

Newhouse B, Allen S, Fauber B, Anderson AS, Eary CT, Hansen JD, Schiro J, Gaudino JJ, Laird E, Chantry D, Eberhardt C, Burgess LE.

Bioorg Med Chem Lett. 2004 Nov 15;14(22):5537-42.

PMID:
15482919
7.

Preferential expression of IgG2b in nose draining cervical lymph nodes and its putative role in mucosal tolerance induction.

van Helvoort JM, Samsom JN, Chantry D, Jansen W, Schadee-Eestermans I, Thepen T, Mebius RE, Kraal G.

Allergy. 2004 Nov;59(11):1211-8.

PMID:
15461604
8.

HIV entry and fusion inhibitors.

Chantry D.

Expert Opin Emerg Drugs. 2004 May;9(1):1-7. Review.

PMID:
15155132
9.

Discovery and SAR of trisubstituted thiazolidinones as CCR4 antagonists.

Allen S, Newhouse B, Anderson AS, Fauber B, Allen A, Chantry D, Eberhardt C, Odingo J, Burgess LE.

Bioorg Med Chem Lett. 2004 Apr 5;14(7):1619-24.

PMID:
15026036
10.
11.

Chemokines in allergy.

Chantry D, Burgess LE.

Curr Drug Targets Inflamm Allergy. 2002 Mar;1(1):109-16. Review.

PMID:
14561210
12.

CCR4-bearing T cells participate in autoimmune diabetes.

Kim SH, Cleary MM, Fox HS, Chantry D, Sarvetnick N.

J Clin Invest. 2002 Dec;110(11):1675-86.

13.

A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation.

Clayton E, Bardi G, Bell SE, Chantry D, Downes CP, Gray A, Humphries LA, Rawlings D, Reynolds H, Vigorito E, Turner M.

J Exp Med. 2002 Sep 16;196(6):753-63.

14.

Presence of high contents of thymus and activation-regulated chemokine in platelets and elevated plasma levels of thymus and activation-regulated chemokine and macrophage-derived chemokine in patients with atopic dermatitis.

Fujisawa T, Fujisawa R, Kato Y, Nakayama T, Morita A, Katsumata H, Nishimori H, Iguchi K, Kamiya H, Gray PW, Chantry D, Suzuki R, Yoshie O.

J Allergy Clin Immunol. 2002 Jul;110(1):139-46.

PMID:
12110833
15.

IFN-gamma-inducible expression of thymus and activation-regulated chemokine/CCL17 and macrophage-derived chemokine/CCL22 in epidermal keratinocytes and their roles in atopic dermatitis.

Horikawa T, Nakayama T, Hikita I, Yamada H, Fujisawa R, Bito T, Harada S, Fukunaga A, Chantry D, Gray PW, Morita A, Suzuki R, Tezuka T, Ichihashi M, Yoshie O.

Int Immunol. 2002 Jul;14(7):767-73.

PMID:
12096036
16.

Metaphor: exploring its origins and therapeutic use in death, dying and bereavement.

Spall B, Read S, Chantry D.

Int J Palliat Nurs. 2001 Jul;7(7):345-53.

PMID:
11951403
17.

Quantitation of chemokines (MDC, TARC) expression in mucosa from Crohn's disease and ulcerative colitis.

Jugde F, Alizadeh M, Boissier C, Chantry D, Siproudhis L, Corbinais S, Quelvennec E, Dyard F, Campion JP, Gosselin M, Bretagne JF, Sémana G, Heresbach D.

Eur Cytokine Netw. 2001 Jul-Sep;12(3):468-77.

18.

Structural organization of the mouse phosphatidylinositol 3-kinase p110d gene.

Clayton E, McAdam S, Coadwell J, Chantry D, Turner M.

Biochem Biophys Res Commun. 2001 Feb 9;280(5):1328-32.

PMID:
11162674
19.

Macrophage-derived chemokine and EBI1-ligand chemokine attract human thymocytes in different stage of development and are produced by distinct subsets of medullary epithelial cells: possible implications for negative selection.

Annunziato F, Romagnani P, Cosmi L, Beltrame C, Steiner BH, Lazzeri E, Raport CJ, Galli G, Manetti R, Mavilia C, Vanini V, Chantry D, Maggi E, Romagnani S.

J Immunol. 2000 Jul 1;165(1):238-46.

20.

KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells.

Stine JT, Wood C, Hill M, Epp A, Raport CJ, Schweickart VL, Endo Y, Sasaki T, Simmons G, Boshoff C, Clapham P, Chang Y, Moore P, Gray PW, Chantry D.

Blood. 2000 Feb 15;95(4):1151-7.

21.

A highly selective CC chemokine receptor (CCR)8 antagonist encoded by the poxvirus molluscum contagiosum.

Lüttichau HR, Stine J, Boesen TP, Johnsen AH, Chantry D, Gerstoft J, Schwartz TW.

J Exp Med. 2000 Jan 3;191(1):171-80.

22.

Macrophage-derived chemokine production by activated human T cells in vitro and in vivo: preferential association with the production of type 2 cytokines.

Galli G, Chantry D, Annunziato F, Romagnani P, Cosmi L, Lazzeri E, Manetti R, Maggi E, Gray PW, Romagnani S.

Eur J Immunol. 2000 Jan;30(1):204-10.

23.

Virally encoded chemokines and chemokine receptors: genetic embezzlement of host DNA.

Stine JT, Chantry D, Gray P.

Chem Immunol. 1999;72:161-80. Review. No abstract available.

PMID:
10550936
24.

Macrophage-derived chemokine is localized to thymic medullary epithelial cells and is a chemoattractant for CD3(+), CD4(+), CD8(low) thymocytes.

Chantry D, Romagnani P, Raport CJ, Wood CL, Epp A, Romagnani S, Gray PW.

Blood. 1999 Sep 15;94(6):1890-8.

25.

Divergent effects of interleukin-4 and interferon-gamma on macrophage-derived chemokine production: an amplification circuit of polarized T helper 2 responses.

Bonecchi R, Sozzani S, Stine JT, Luini W, D'Amico G, Allavena P, Chantry D, Mantovani A.

Blood. 1998 Oct 15;92(8):2668-71.

26.

Profile of human macrophage transcripts: insights into macrophage biology and identification of novel chemokines.

Chantry D, DeMaggio AJ, Brammer H, Raport CJ, Wood CL, Schweickart VL, Epp A, Smith A, Stine JT, Walton K, Tjoelker L, Godiska R, Gray PW.

J Leukoc Biol. 1998 Jul;64(1):49-54. Review.

PMID:
9665274
27.

Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4.

Imai T, Chantry D, Raport CJ, Wood CL, Nishimura M, Godiska R, Yoshie O, Gray PW.

J Biol Chem. 1998 Jan 16;273(3):1764-8.

28.

p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes.

Chantry D, Vojtek A, Kashishian A, Holtzman DA, Wood C, Gray PW, Cooper JA, Hoekstra MF.

J Biol Chem. 1997 Aug 1;272(31):19236-41.

29.

Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells.

Godiska R, Chantry D, Raport CJ, Sozzani S, Allavena P, Leviten D, Mantovani A, Gray PW.

J Exp Med. 1997 May 5;185(9):1595-604.

30.

Cloning and characterization of exodus, a novel beta-chemokine.

Hromas R, Gray PW, Chantry D, Godiska R, Krathwohl M, Fife K, Bell GI, Takeda J, Aronica S, Gordon M, Cooper S, Broxmeyer HE, Klemsz MJ.

Blood. 1997 May 1;89(9):3315-22.

31.

Monocyte chemotactic protein-4: tissue-specific expression and signaling through CC chemokine receptor-2.

Godiska R, Chantry D, Raport CJ, Schweickart VL, Trong HL, Gray PW.

J Leukoc Biol. 1997 Mar;61(3):353-60.

PMID:
9060459
32.

New members of the chemokine receptor gene family.

Raport CJ, Schweickart VL, Chantry D, Eddy RL Jr, Shows TB, Godiska R, Gray PW.

J Leukoc Biol. 1996 Jan;59(1):18-23. Review.

PMID:
8558062
33.

Chemokine expression in murine experimental allergic encephalomyelitis.

Godiska R, Chantry D, Dietsch GN, Gray PW.

J Neuroimmunol. 1995 May;58(2):167-76.

PMID:
7539012
34.

Cytokine production by cholesterol-loaded human peripheral monocyte-macrophages: the effect on fibrinogen mRNA levels in a hepatoma cell-line (HepG2).

Lane A, Graham L, Cook M, Chantry D, Green F, Nigon F, Humphries SE.

Biochim Biophys Acta. 1991 Oct 21;1097(3):161-5.

PMID:
1932138
35.

Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-alpha.

Haworth C, Brennan FM, Chantry D, Turner M, Maini RN, Feldmann M.

Eur J Immunol. 1991 Oct;21(10):2575-9.

PMID:
1915559
36.

Induction of the interleukin 1 receptor antagonist protein by transforming growth factor-beta.

Turner M, Chantry D, Katsikis P, Berger A, Brennan FM, Feldmann M.

Eur J Immunol. 1991 Jul;21(7):1635-9.

PMID:
1829411
37.

Production of interleukin-1 and interleukin-6 by human keratinocytes and squamous cell carcinoma cell lines.

Partridge M, Chantry D, Turner M, Feldmann M.

J Invest Dermatol. 1991 May;96(5):771-6.

38.

Cytokine assays: role in evaluation of the pathogenesis of autoimmunity.

Feldmann M, Brennan FM, Chantry D, Haworth C, Turner M, Katsikis P, Londei M, Abney E, Buchan G, Barrett K, et al.

Immunol Rev. 1991 Feb;119:105-23. Review.

PMID:
2045116
39.

Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein.

Gray PW, Barrett K, Chantry D, Turner M, Feldmann M.

Proc Natl Acad Sci U S A. 1990 Oct;87(19):7380-4.

40.

Detection of interleukin 8 biological activity in synovial fluids from patients with rheumatoid arthritis and production of interleukin 8 mRNA by isolated synovial cells.

Brennan FM, Zachariae CO, Chantry D, Larsen CG, Turner M, Maini RN, Matsushima K, Feldmann M.

Eur J Immunol. 1990 Sep;20(9):2141-4.

PMID:
2209707
41.
42.

Cytokine production in the rheumatoid joint: implications for treatment.

Feldmann M, Brennan FM, Chantry D, Haworth C, Turner M, Abney E, Buchan G, Barrett K, Barkley D, Chu A, et al.

Ann Rheum Dis. 1990 Jun;49 Suppl 1:480-6. Review.

43.
44.

Granulocyte-macrophage colony stimulating factor induces both HLA-DR expression and cytokine production by human monocytes.

Chantry D, Turner M, Brennan F, Kingsbury A, Feldmann M.

Cytokine. 1990 Jan;2(1):60-7.

PMID:
2129500
45.

Interleukin 7 and interleukin 4 stimulate human thymocyte growth through distinct mechanisms.

Varma C, Chantry D, Brennan F, Turner M, Katz F, Feldmann M.

Cytokine. 1990 Jan;2(1):55-9.

PMID:
2104214
46.

Regulation of expression of human IL-1 alpha and IL-1 beta genes.

Turner M, Chantry D, Buchan G, Barrett K, Feldmann M.

J Immunol. 1989 Dec 1;143(11):3556-61.

PMID:
2511244
47.

Analysis of intrathyroidal cytokine production in thyroid autoimmune disease: thyroid follicular cells produce interleukin-1 alpha and interleukin-6.

Grubeck-Loebenstein B, Buchan G, Chantry D, Kassal H, Londei M, Pirich K, Barrett K, Turner M, Waldhausl W, Feldmann M.

Clin Exp Immunol. 1989 Sep;77(3):324-30.

48.

Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis.

Brennan FM, Chantry D, Jackson A, Maini R, Feldmann M.

Lancet. 1989 Jul 29;2(8657):244-7.

PMID:
2569055
49.

Modulation of cytokine production by transforming growth factor-beta.

Chantry D, Turner M, Abney E, Feldmann M.

J Immunol. 1989 Jun 15;142(12):4295-300.

PMID:
2542408
50.

Intrathyroidal cytokine production in thyroid disease.

Grubeck-Loebenstein B, Buchan G, Chantry D, Turner M, Londei M, Feldmann M.

J Autoimmun. 1989 Jun;2 Suppl:171-6.

PMID:
2673271

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