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[Diagnostic Value of G and GM Tests in Acute Leukemia Patients with Invasive Fungal Disease].

Qian KY, Lyu QX, Dai LJ, Chang HR, Wu DP, Sun AN.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019 Oct;27(5):1678-1681. doi: 10.19746/j.cnki.issn.1009-2137.2019.05.049. Chinese.


Intermittent Hypoxia Induces Autophagy to Protect Cardiomyocytes From Endoplasmic Reticulum Stress and Apoptosis.

Chang JC, Hu WF, Lee WS, Lin JH, Ting PC, Chang HR, Shieh KR, Chen TI, Yang KT.

Front Physiol. 2019 Aug 7;10:995. doi: 10.3389/fphys.2019.00995. eCollection 2019.


Fisetin Suppresses the Proliferation and Metastasis of Renal Cell Carcinoma through Upregulation of MEK/ERK-Targeting CTSS and ADAM9.

Hsieh MH, Tsai JP, Yang SF, Chiou HL, Lin CL, Hsieh YH, Chang HR.

Cells. 2019 Aug 21;8(9). pii: E948. doi: 10.3390/cells8090948.


Role of LpL (Lipoprotein Lipase) in Macrophage Polarization In Vitro and In Vivo.

Chang HR, Josefs T, Scerbo D, Gumaste N, Hu Y, Huggins LA, Barrett TJ, Chiang SS, Grossman J, Bagdasarov S, Fisher EA, Goldberg IJ.

Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):1967-1985. doi: 10.1161/ATVBAHA.119.312389. Epub 2019 Aug 22.


Thymoquinone suppresses the proliferation of renal cell carcinoma cells via reactive oxygen species-induced apoptosis and reduces cell stemness.

Liou YF, Chen PN, Chu SC, Kao SH, Chang YZ, Hsieh YS, Chang HR.

Environ Toxicol. 2019 Nov;34(11):1208-1220. doi: 10.1002/tox.22822. Epub 2019 Jul 12.


Antiaging and smoothness-improving properties of farnesol-based facial masks on rat skin exposed to ultraviolet B.

Huang YW, Huang HH, Wu GX, Chang HR, Wu KL, Kuo SM.

J Cosmet Dermatol. 2019 Jun 27. doi: 10.1111/jocd.13046. [Epub ahead of print]


Thymoquinone inhibits metastasis of renal cell carcinoma cell 786-O-SI3 associating with downregulation of MMP-2 and u-PA and suppression of PI3K/Src signaling.

Liou YF, Hsieh YS, Hung TW, Chen PN, Chang YZ, Kao SH, Lin SW, Chang HR.

Int J Med Sci. 2019 May 10;16(5):686-695. doi: 10.7150/ijms.32763. eCollection 2019.


Intermittent Hypoxia Prevents Myocardial Mitochondrial Ca2+ Overload and Cell Death during Ischemia/Reperfusion: The Role of Reactive Oxygen Species.

Chang JC, Lien CF, Lee WS, Chang HR, Hsu YC, Luo YP, Jeng JR, Hsieh JC, Yang KT.

Cells. 2019 Jun 9;8(6). pii: E564. doi: 10.3390/cells8060564.


Predictors of Emergency Department Use Among Community-Dwelling Older Adults.

Ho MH, Wang CH, Joo JY, Chang HR, Chang CC, Liu MF.

J Gerontol Nurs. 2019 May 1;45(5):31-38. doi: 10.3928/00989134-20190404-02.


The uremic toxin p-cresol promotes the invasion and migration on carcinoma cells via Ras and mTOR signaling.

Hsu YH, Huang HP, Chang HR.

Toxicol In Vitro. 2019 Aug;58:126-131. doi: 10.1016/j.tiv.2019.03.029. Epub 2019 Mar 22.


Hypomorphic Mutations in TONSL Cause SPONASTRIME Dysplasia.

Chang HR, Cho SY, Lee JH, Lee E, Seo J, Lee HR, Cavalcanti DP, Mäkitie O, Valta H, Girisha KM, Lee C, Neethukrishna K, Bhavani GS, Shukla A, Nampoothiri S, Phadke SR, Park MJ, Ikegawa S, Wang Z, Higgs MR, Stewart GS, Jung E, Lee MS, Park JH, Lee EA, Kim H, Myung K, Jeon W, Lee K, Kim D, Kim OH, Choi M, Lee HW, Kim Y, Cho TJ.

Am J Hum Genet. 2019 Mar 7;104(3):439-453. doi: 10.1016/j.ajhg.2019.01.009. Epub 2019 Feb 14.


Establishment of Classification of Tibial Plateau Fracture Associated with Proximal Fibular Fracture.

Zheng ZL, Yu YY, Chang HR, Liu H, Zhou HL, Zhang YZ.

Orthop Surg. 2019 Feb;11(1):97-101. doi: 10.1111/os.12424. Epub 2019 Feb 8.


Endothelial cell CD36 optimizes tissue fatty acid uptake.

Son NH, Basu D, Samovski D, Pietka TA, Peche VS, Willecke F, Fang X, Yu SQ, Scerbo D, Chang HR, Sun F, Bagdasarov S, Drosatos K, Yeh ST, Mullick AE, Shoghi KI, Gumaste N, Kim K, Huggins LA, Lhakhang T, Abumrad NA, Goldberg IJ.

J Clin Invest. 2018 Oct 1;128(10):4329-4342. doi: 10.1172/JCI99315. Epub 2018 Jul 26.


Integrated multiomic predictors for ovarian cancer survival.

Fu A, Chang HR, Zhang ZF.

Carcinogenesis. 2018 Jul 3;39(7):860-868. doi: 10.1093/carcin/bgy055.


Percutaneous Reduction and Internal Fixation for Monocondylar Fractures of Tibial Plateau: A Systematic Review.

Chang HR, Yu YY, Ju LL, Zheng ZL, Chen W, Zhang YZ.

Orthop Surg. 2018 May;10(2):77-83. doi: 10.1111/os.12372. Epub 2018 May 16. Review.


Intermittent Hypoxia Inhibits Na+-H+ Exchange-Mediated Acid Extrusion Via Intracellular Na+ Accumulation in Cardiomyocytes.

Chang HR, Lien CF, Jeng JR, Hsieh JC, Chang CW, Lin JH, Yang KT.

Cell Physiol Biochem. 2018;46(3):1252-1262. doi: 10.1159/000489076. Epub 2018 Apr 16.


Comparison of Renal Function and Other Predictors in Lacto-Ovo Vegetarians and Omnivores With Chronic Kidney Disease.

Chang CY, Chang HR, Lin HC, Chang HH.

J Am Coll Nutr. 2018 Aug;37(6):466-471. doi: 10.1080/07315724.2018.1424588. Epub 2018 Mar 13.


Evaluation of the UVB-screening capacity and restorative effects exerted by farnesol gel on UVB-caused sunburn.

Wu GX, Huang HH, Chang HR, Kuo SM.

Environ Toxicol. 2018 Apr;33(4):488-507. doi: 10.1002/tox.22535. Epub 2018 Jan 30.


Ring finger protein 126 (RNF126) suppresses ionizing radiation-induced p53-binding protein 1 (53BP1) focus formation.

Lee NS, Chang HR, Kim S, Ji JH, Lee J, Lee HJ, Seo Y, Kang M, Han JS, Myung K, Kim Y, Kim H.

J Biol Chem. 2018 Jan 12;293(2):588-598. doi: 10.1074/jbc.M116.765602. Epub 2017 Nov 22.


CANcer-specific Evaluation System (CANES): a high-accuracy platform, for preclinical single/multi-biomarker discovery.

Kwon MS, Nam S, Lee S, Ahn YZ, Chang HR, Kim YH, Park T.

Oncotarget. 2017 Jul 15;8(41):69808-69822. doi: 10.18632/oncotarget.19270. eCollection 2017 Sep 19.


Chromatographic determination, decline dynamic and risk assessment of sulfoxaflor in Asian pear and oriental melon.

Kabir MH, Abd El-Aty AM, Rahman MM, Chung HS, Lee HS, Kim SW, Chang HR, Shin HC, Shin SS, Shim JH.

Biomed Chromatogr. 2018 Mar;32(3). doi: 10.1002/bmc.4101. Epub 2017 Nov 8.


Rules for functional microRNA targeting.

Kim D, Chang HR, Baek D.

BMB Rep. 2017 Nov;50(11):554-559. Review.


Kaempferol Inhibits the Invasion and Migration of Renal Cancer Cells through the Downregulation of AKT and FAK Pathways.

Hung TW, Chen PN, Wu HC, Wu SW, Tsai PY, Hsieh YS, Chang HR.

Int J Med Sci. 2017 Aug 18;14(10):984-993. doi: 10.7150/ijms.20336. eCollection 2017.


Symmetrical peripheral gangrene in sepsis after treatment with inotropes.

Jiang JL, Tseng LW, Chang HR.

Ci Ji Yi Xue Za Zhi. 2017 Apr-Jun;29(2):121-124. doi: 10.4103/tcmj.tcmj_25_17.


Lipopolysaccharides induce Smad2 phosphorylation through PI3K/Akt and MAPK cascades in HSC-T6 hepatic stellate cells.

Kao YH, Chen PH, Wu TY, Lin YC, Tsai MS, Lee PH, Tai TS, Chang HR, Sun CK.

Life Sci. 2017 Sep 1;184:37-46. doi: 10.1016/j.lfs.2017.07.004. Epub 2017 Jul 6.


Intravitreal itraconazole inhibits laser-induced choroidal neovascularization in rats.

Bae JH, Hwang AR, Kim CY, Yu HG, Koh HJ, Yang WI, Chang HR, Lee SC.

PLoS One. 2017 Jun 30;12(6):e0180482. doi: 10.1371/journal.pone.0180482. eCollection 2017.


The gender difference and mortality-to-incidence ratio relate to health care disparities in bladder cancer: National estimates from 33 countries.

Wang SC, Sung WW, Kao YL, Hsieh TY, Chen WJ, Chen SL, Chang HR.

Sci Rep. 2017 Jun 28;7(1):4360. doi: 10.1038/s41598-017-04083-z.


The functional roles of PML nuclear bodies in genome maintenance.

Chang HR, Munkhjargal A, Kim MJ, Park SY, Jung E, Ryu JH, Yang Y, Lim JS, Kim Y.

Mutat Res. 2018 May;809:99-107. doi: 10.1016/j.mrfmmm.2017.05.002. Epub 2017 May 5. Review.


CD24 Expression and differential resistance to chemotherapy in triple-negative breast cancer.

Deng X, Apple S, Zhao H, Song J, Lee M, Luo W, Wu X, Chung D, Pietras RJ, Chang HR.

Oncotarget. 2017 Jun 13;8(24):38294-38308. doi: 10.18632/oncotarget.16203.


Various UVB doses affect change of raf kinase inhibitor protein, nitric oxide and proliferation in keratinocytes.

Wu CS, Tsao DA, Yu HS, Chien CY, Chang HR.

Toxicol In Vitro. 2017 Aug;42:101-104. doi: 10.1016/j.tiv.2017.04.011. Epub 2017 Apr 13.


Clinical significance linked to functional defects in bone morphogenetic protein type 2 receptor, BMPR2.

Kim MJ, Park SY, Chang HR, Jung EY, Munkhjargal A, Lim JS, Lee MS, Kim Y.

BMB Rep. 2017 Jun;50(6):308-317.


Everolimus suppresses invasion and migration of renal cell carcinoma by inhibiting FAK activity and reversing epithelial to mesenchymal transition in vitro and in vivo.

Wu SW, Chen PN, Lin CY, Hsieh YS, Chang HR.

Environ Toxicol. 2017 Jul;32(7):1888-1898. doi: 10.1002/tox.22411. Epub 2017 Mar 4.


[Comparison of allogeneic or autologous hematopoietic stem cell transplant for high-risk peripheral T cell lymphomas].

Wang QL, Huang HW, Jin ZM, Tang XW, Qiu HY, Fu CC, Han Y, Miao M, Chang HR, Sun AN, Wu DP.

Zhonghua Xue Ye Xue Za Zhi. 2016 Nov 14;37(11):952-956. doi: 10.3760/cma.j.issn.0253-2727.2016.11.005. Chinese.


Pentraxin 3 Activates JNK Signaling and Regulates the Epithelial-To-Mesenchymal Transition in Renal Fibrosis.

Hung TW, Tsai JP, Lin SH, Lee CH, Hsieh YH, Chang HR.

Cell Physiol Biochem. 2016;40(5):1029-1038. Epub 2016 Dec 12.


Different impact of aspirin on renal progression in patients with predialysis advanced chronic kidney disease with or without previous stroke.

Hsiao KC, Huang JY, Lee CT, Hung TW, Liaw YP, Chang HR.

Eur J Intern Med. 2017 Apr;39:63-68. doi: 10.1016/j.ejim.2016.11.009. Epub 2016 Nov 21.


ERBB2 mutation is associated with a worse prognosis in patients with CDH1 altered invasive lobular cancer of the breast.

Ping Z, Siegal GP, Harada S, Eltoum IE, Youssef M, Shen T, He J, Huang Y, Chen D, Li Y, Bland KI, Chang HR, Shen D.

Oncotarget. 2016 Dec 6;7(49):80655-80663. doi: 10.18632/oncotarget.13019.


Systematic approach identifies RHOA as a potential biomarker therapeutic target for Asian gastric cancer.

Chang HR, Nam S, Lee J, Kim JH, Jung HR, Park HS, Park S, Ahn YZ, Huh I, Balch C, Ku JL, Powis G, Park T, Jeong JH, Kim YH.

Oncotarget. 2016 Dec 6;7(49):81435-81451. doi: 10.18632/oncotarget.12963.


Bo-Gan-Whan regulates proliferation and migration of vascular smooth muscle cells.

Lee KP, Kim JE, Kim H, Chang HR, Lee DW, Park WH.

BMC Complement Altern Med. 2016 Aug 22;16(1):306. doi: 10.1186/s12906-016-1292-9.


Comparison of SPE, IFE, and FLC in Monitoring Patients with Multiple Myeloma After Autologous Stem Cell Transplantation.

Li W, Zhou JZ, Chang HR, Dai LJ, Zhu ZL, Feng YF, Gong FR, Wu DP.

Cell Biochem Biophys. 2015 Dec;73(3):643-7. doi: 10.1007/s12013-015-0655-z.


RKIP expression of liver and kidney after arsenic exposure.

Tsao DA, Tseng WC, Chang HR.

Environ Toxicol. 2017 Mar;32(3):1079-1082. doi: 10.1002/tox.22291. Epub 2016 Jun 3.


[The roles of serum free light chain ratio in the diagnosis and prognosis of newly diagnosed multiple myeloma].

Wang PF, Xu Y, Yan S, Yao Y, Zheng HF, Ma L, Jin S, Xu Y, Gong FR, Zhou JZ, Chang HR, Fu CC.

Zhonghua Xue Ye Xue Za Zhi. 2016 May 14;37(5):377-82. doi: 10.3760/cma.j.issn.0253-2727.2016.05.005. Chinese.


Trajectories of Serum Albumin Predict Survival of Peritoneal Dialysis Patients: A 15-year Follow-Up Study.

Chiu PF, Tsai CC, Wu CL, Yang TY, Liou HH, Chen HL, Kor CT, Chang CC, Chang HR.

Medicine (Baltimore). 2016 Mar;95(12):e3202. doi: 10.1097/MD.0000000000003202.


Improving gastric cancer preclinical studies using diverse in vitro and in vivo model systems.

Chang HR, Park HS, Ahn YZ, Nam S, Jung HR, Park S, Lee SJ, Balch C, Powis G, Ku JL, Kim YH.

BMC Cancer. 2016 Mar 9;16:200. doi: 10.1186/s12885-016-2232-2.


Quantification of peri-aortic root fat from non-contrast ECG-gated cardiac computed tomography.

Yun CH, Longenecker CT, Chang HR, Mok GS, Sun JY, Liu CC, Kuo JY, Hung CL, Wu TH, Yeh HI, Yang FS, Lee JJ, Hou CJ, Cury RC, Bezerra HG.

Data Brief. 2015 Nov 19;5:995-8. doi: 10.1016/j.dib.2015.11.022. eCollection 2015 Dec.


Association of Sitagliptin with cardiovascular outcome in diabetic patients: a nationwide cohort study.

Yang TY, Liaw YP, Huang JY, Chang HR, Chang KW, Ueng KC.

Acta Diabetol. 2016 Jun;53(3):461-8. doi: 10.1007/s00592-015-0817-x. Epub 2015 Dec 21.


Sudden Cardiac Death Associated with Anomalous Origin of the Left Main Coronary Artery from the Right Sinus, with an Intramural Course.

Chang HR, Hsieh JC, Chao SF, Wang JH, Stephen Huang SK.

Tex Heart Inst J. 2015 Dec 1;42(6):554-7. doi: 10.14503/THIJ-14-4249. eCollection 2015 Dec.


Macrophage and adipocyte IGF1 maintain adipose tissue homeostasis during metabolic stresses.

Chang HR, Kim HJ, Xu X, Ferrante AW Jr.

Obesity (Silver Spring). 2016 Jan;24(1):172-83. doi: 10.1002/oby.21354. Epub 2015 Dec 10.


MMP-2 serum concentrations predict mortality in hemodialysis patients: a 5-year cohort study.

Hsiao KC, Tsai JP, Yang SF, Lee WC, Huang JY, Chang SC, Hso CS, Chang HR.

Clin Chim Acta. 2016 Jan 15;452:161-6. doi: 10.1016/j.cca.2015.11.019. Epub 2015 Nov 26. Erratum in: Clin Chim Acta. 2016 Apr 1;455:209.


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