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Efficacy and Safety of Udenafil for the Treatment of Pulmonary Arterial Hypertension: a Placebo-controlled, Double-blind, Phase IIb Clinical Trial.

Chang HJ, Song S, Chang SA, Kim HK, Jung HO, Choi JH, Lee JS, Kim KH, Jeong JO, Lee JH, Kim DK.

Clin Ther. 2019 Jun 12. pii: S0149-2918(19)30251-6. doi: 10.1016/j.clinthera.2019.05.006. [Epub ahead of print]


Relationships among demands at work, aggression, and verbal abuse among registered nurses in South Korea.

Chang HE, Park MY, Jang H, Ahn S, Yoon HJ.

Nurs Outlook. 2019 May 1. pii: S0029-6554(18)30564-5. doi: 10.1016/j.outlook.2019.04.007. [Epub ahead of print]


mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV.

Yang JY, Madrakhimov SB, Ahn DH, Chang HS, Jung SJ, Nah SK, Park HY, Park TK.

Cell Commun Signal. 2019 Jun 14;17(1):64. doi: 10.1186/s12964-019-0380-0.


Fabrication of Hydrophilic Surface on Rigid Gas Permeable Contact Lenses to Enhance the Wettability Using Ultraviolet Laser System.

Tsai HY, Hsieh YC, Lin YH, Chang HC, Tang YH, Huang KC.

Micromachines (Basel). 2019 Jun 13;10(6). pii: E394. doi: 10.3390/mi10060394.


Macrophages are the primary effector cells in IL-7-induced arthritis.

Kim SJ, Chang HJ, Volin MV, Umar S, Van Raemdonck K, Chevalier A, Palasiewicz K, Christman JW, Volkov S, Arami S, Maz M, Mehta A, Zomorrodi RK, Fox DA, Sweiss N, Shahrara S.

Cell Mol Immunol. 2019 Jun 13. doi: 10.1038/s41423-019-0235-z. [Epub ahead of print]


Quasi-Saturated Layer: Implications for Estimating Recharge and Groundwater Modeling.

Gonçalves RD, Teramoto EH, Engelbrecht BZ, Alfaro Soto MA, Chang HK, van Genuchten MT.

Ground Water. 2019 Jun 12. doi: 10.1111/gwat.12916. [Epub ahead of print]


Identification of potential metabolic biomarkers of polycystic ovary syndrome in follicular fluid by SWATH mass spectrometry.

Sun Z, Chang HM, Wang A, Song J, Zhang X, Guo J, Leung PCK, Lian F.

Reprod Biol Endocrinol. 2019 Jun 11;17(1):45. doi: 10.1186/s12958-019-0490-y.


Burden of disease from Helicobacter pylori infection in western Canadian Arctic communities.

Fagan-Garcia K, Geary J, Chang HJ, McAlpine L, Walker E, Colquhoun A, van Zanten SV, Girgis S, Archie B, Hanley B, Corriveau A, Morse J, Munday R, Goodman KJ; CANHelp Working Group.

BMC Public Health. 2019 Jun 11;19(1):730. doi: 10.1186/s12889-019-7065-x.


ALK4-SMAD2/3-SMAD4 signaling mediates the activin A-induced suppression of PTX3 in human granulosa-lutein cells.

Liu C, Chang HM, Yi Y, Fang Y, Zhao F, Leung PCK, Yang X.

Mol Cell Endocrinol. 2019 Jun 8;493:110485. doi: 10.1016/j.mce.2019.110485. [Epub ahead of print]


Transcriptome analysis of responses to bluetongue virus infection in Aedes albopictus cells.

Du J, Gao S, Tian Z, Guo Y, Kang D, Xing S, Zhang G, Liu G, Luo J, Chang H, Yin H.

BMC Microbiol. 2019 Jun 10;19(1):121. doi: 10.1186/s12866-019-1498-3.


Intermittent Hypoxia Prevents Myocardial Mitochondrial Ca2+ Overload and Cell Death during Ischemia/Reperfusion: The Role of Reactive Oxygen Species.

Chang JC, Lien CF, Lee WS, Chang HR, Hsu YC, Luo YP, Jeng JR, Hsieh JC, Yang KT.

Cells. 2019 Jun 9;8(6). pii: E564. doi: 10.3390/cells8060564.


Collagen 1A1 (COL1A1) Is a Reliable Biomarker and Putative Therapeutic Target for Hepatocellular Carcinogenesis and Metastasis.

Ma HP, Chang HL, Bamodu OA, Yadav VK, Huang TY, Wu ATH, Yeh CT, Tsai SH, Lee WH.

Cancers (Basel). 2019 Jun 7;11(6). pii: E786. doi: 10.3390/cancers11060786.


Phthalates and organophosphorus insecticide residues in shrimp determined by liquid/gas chromatography-Tandem mass spectrometry and a health risk assessment.

Chang HY, Yang WC, Xue YJ, Tsai MY, Wang JH, Chang GR.

Mar Pollut Bull. 2019 Jul;144:140-145. doi: 10.1016/j.marpolbul.2019.04.047. Epub 2019 May 16.


Synergistic Effect of Combined Treatment with Longan Flower Extract and 5-Fluorouracil on Colorectal Cancer Cells.

Chen SJ, Chung YC, Chang HL, Chang HP, Chou JL, Lin CC, Chen CH, Hsu CP.

Nutr Cancer. 2019 Jun 10:1-9. doi: 10.1080/01635581.2019.1622739. [Epub ahead of print]


Stereodynamic Imaging of Bromine Atomic Photofragments Eliminated from 1-Bromo-2-Methylbutane Oriented via Hexapole State Selector.

Nakamura M, Chang HP, Lin KC, Kasai T, Che DC, Palazzetti F, Aquilanti V.

J Phys Chem A. 2019 Jun 8. doi: 10.1021/acs.jpca.9b04048. [Epub ahead of print]


Effect of pretreatment with combined oral contraceptives on outcomes of assisted reproductive technology for women with polycystic ovary syndrome: a meta-analysis.

Song SY, Yang JB, Song MS, Oh HY, Lee GW, Lee M, Ko YB, Lee KH, Chang HK, Kwak SM, Yoo HJ.

Arch Gynecol Obstet. 2019 Jun 6. doi: 10.1007/s00404-019-05210-z. [Epub ahead of print]


Attenuated vagally-mediated heart rate variability at rest and in response to postural maneuvers in patients with generalized anxiety disorder.

Chang HA, Fang WH, Wan FJ, Tzeng NS, Liu YP, Shyu JF, Chang TC, Huang SY, Chang CC.

Psychol Med. 2019 Jun 7:1-9. doi: 10.1017/S0033291719001302. [Epub ahead of print]


Ethyl Acetate Extract of Nepenthes ventricosa x maxima Exerts Preferential Killing to Oral Cancer Cells.

Tang JY, Li LJ, Ou-Yang F, Wang CL, Shu CW, Wu KH, Wang HR, Yen CH, Cheng YB, Chang HW.

DNA Cell Biol. 2019 Jun 6. doi: 10.1089/dna.2018.4436. [Epub ahead of print]


Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells.

Timilshina M, You Z, Lacher SM, Acharya S, Jiang L, Kang Y, Kim JA, Chang HW, Kim KJ, Park B, Song JH, Ko HJ, Park YY, Ma MJ, Nepal MR, Jeong TC, Chung Y, Waisman A, Chang JH.

Cell Rep. 2019 Jun 4;27(10):2948-2961.e7. doi: 10.1016/j.celrep.2019.05.020.


Enhancement in speed and responsivity of uni-traveling carrier photodiodes with GaAs0.5Sb0.5/In0.53Ga0.47As type-II hybrid absorbers.

Naseem, Ahmad Z, Chao RL, Chang HS, Ni CJ, Chen HS, Huang JJ, Chou E, Jan YH, Shi JW.

Opt Express. 2019 May 27;27(11):15495-15504. doi: 10.1364/OE.27.015495.


CD56+ B-cell Neurolymphomatosis in a Cat.

Hsueh CS, Tsai CY, Lee JC, Kao CL, Wang FI, Jeng CR, Chang HW, Pang VF, Liu CH.

J Comp Pathol. 2019 May;169:25-29. doi: 10.1016/j.jcpa.2019.03.004. Epub 2019 May 13.


Xanthium strumarium Fruit Extract Inhibits ATG4B and Diminishes the Proliferation and Metastatic Characteristics of Colorectal Cancer Cells.

Chang HW, Liu PF, Tsai WL, Hu WH, Hu YC, Yang HC, Lin WY, Weng JR, Shu CW.

Toxins (Basel). 2019 Jun 2;11(6). pii: E313. doi: 10.3390/toxins11060313.


Radical Intracapsular Dissection Technique for Dumbbell-Shaped Spinal Schwannoma with Intradural and Extradural Components.

Chang HS, Baba T, Matsumae M.

World Neurosurg. 2019 May 31. pii: S1878-8750(19)31509-8. doi: 10.1016/j.wneu.2019.05.232. [Epub ahead of print]


Development, integration and use of an ultra-high-strength gradient system on a human-size 3 T magnet for small animal MRI.

Cho KH, Huang SM, Choi CH, Chen MJ, Chiang HH, Buschbeck RP, Farrher E, Shah NJ, Garipov R, Chang CP, Chang H, Kuo LW.

PLoS One. 2019 Jun 3;14(6):e0217916. doi: 10.1371/journal.pone.0217916. eCollection 2019.


Ethyl acetate extract of Nepenthes adrianii x clipeata induces antiproliferation, apoptosis, and DNA damage against oral cancer cells through oxidative stress.

Tang JY, Peng SY, Cheng YB, Wang CL, Farooqi AA, Yu TJ, Hou MF, Wang SC, Yen CH, Chan LP, Ou-Yang F, Chang HW.

Environ Toxicol. 2019 Jun 3. doi: 10.1002/tox.22748. [Epub ahead of print]


Atomic-Level Customization of 4 in. Transition Metal Dichalcogenide Multilayer Alloys for Industrial Applications.

Lim YR, Han JK, Yoon Y, Lee JB, Jeon C, Choi M, Chang H, Park N, Kim JH, Lee Z, Song W, Myung S, Lee SS, An KS, Ahn JH, Lim J.

Adv Mater. 2019 Jun 3:e1901405. doi: 10.1002/adma.201901405. [Epub ahead of print]


Cognitive Diagnostic Models With Attribute Hierarchies: Model Estimation With a Restricted Q-Matrix Design.

Tu D, Wang S, Cai Y, Douglas J, Chang HH.

Appl Psychol Meas. 2019 Jun;43(4):255-271. doi: 10.1177/0146621618765721. Epub 2018 Apr 16.


Single-Molecule Nanoscopy Elucidates RNA Polymerase II Transcription at Single Genes in Live Cells.

Li J, Dong A, Saydaminova K, Chang H, Wang G, Ochiai H, Yamamoto T, Pertsinidis A.

Cell. 2019 May 27. pii: S0092-8674(19)30557-4. doi: 10.1016/j.cell.2019.05.029. [Epub ahead of print]


IgG4-related Ophthalmic Disease in Idiopathic Sclerosing and Non-Sclerosing Orbital Inflammation: A 25-Year Experience.

Tsai CY, Kuo KT, Cheng AMS, Wei YH, Chang HC, Chang K, Liao SL.

Curr Eye Res. 2019 Jun 13:1-6. doi: 10.1080/02713683.2019.1627462. [Epub ahead of print]


Interactome Analyses implicated CAMK2A in the genetic predisposition and pharmacological mechanism of Bipolar Disorder.

Li H, Zhou DS, Chang H, Wang L, Liu W, Dai SX, Zhang C, Cai J, Liu W, Li X, Fan W, Tang W, Tang W, Liu F, He Y, Bai Y, Hu Z, Xiao X, Gao L, Li M.

J Psychiatr Res. 2019 Aug;115:165-175. doi: 10.1016/j.jpsychires.2019.05.024. Epub 2019 May 25.


LNAPL saturation derived from laser induced fluorescence method.

Teramoto EH, Isler E, Polese L, Baessa MPM, Chang HK.

Sci Total Environ. 2019 May 22;683:762-772. doi: 10.1016/j.scitotenv.2019.05.262. [Epub ahead of print]


A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm.

Kilic O, Yoon A, Shah SR, Yong HM, Ruiz-Valls A, Chang H, Panettieri RA Jr, Liggett SB, Quiñones-Hinojosa A, An SS, Levchenko A.

Nat Biomed Eng. 2019 Mar 11. doi: 10.1038/s41551-019-0366-7. [Epub ahead of print]


Single-cell transcriptomes of murine bone marrow stromal cells reveal niche-associated heterogeneity.

Addo RK, Heinrich F, Heinz GA, Schulz D, Sercan-Alp Ö, Lehmann K, Tran CL, Bardua M, Matz M, Löhning M, Hauser AE, Kruglov A, Chang HD, Durek P, Radbruch A, Mashreghi MF.

Eur J Immunol. 2019 May 31. doi: 10.1002/eji.201848053. [Epub ahead of print]


Oral manifestation and root canal therapy of the patient with mucopolysaccharidosis.

Yoon JH, Lee HI, Jang JH, Choi SH, Chang HS, Hwang YC, Hwang IN, Lee BN, Oh WM.

Restor Dent Endod. 2019 Apr 4;44(2):e14. doi: 10.5395/rde.2019.44.e14. eCollection 2019 May.


Doxycycline inhibits electric field-induced migration of non-small cell lung cancer (NSCLC) cells.

Chang HF, Cheng HT, Chen HY, Yeung WK, Cheng JY.

Sci Rep. 2019 May 30;9(1):8094. doi: 10.1038/s41598-019-44505-8.


Antiviral activity of brequinar against foot-and-mouth disease virus infection in vitro and in vivo.

Li SF, Gong MJ, Sun YF, Shao JJ, Zhang YG, Chang HY.

Biomed Pharmacother. 2019 May 27;116:108982. doi: 10.1016/j.biopha.2019.108982. [Epub ahead of print]


Elimination of Omega-1,2 Gliadins From Bread Wheat (Triticum aestivum) Flour: Effects on Immunogenic Potential and End-Use Quality.

Altenbach SB, Chang HC, Yu XB, Seabourn BW, Green PH, Alaedini A.

Front Plant Sci. 2019 May 9;10:580. doi: 10.3389/fpls.2019.00580. eCollection 2019.


Antidepressant-Like Effect and Mechanism of Action of Honokiol on the Mouse Lipopolysaccharide (LPS) Depression Model.

Zhang B, Wang PP, Hu KL, Li LN, Yu X, Lu Y, Chang HS.

Molecules. 2019 May 28;24(11). pii: E2035. doi: 10.3390/molecules24112035.


Sulfonyl chromen-4-ones (CHW09) shows an additive effect to inhibit cell growth of X-ray irradiated oral cancer cells, involving apoptosis and ROS generation.

Tang JY, Shu CW, Wang CL, Wang SC, Chang MY, Lin LC, Chang HW.

Int J Radiat Biol. 2019 May 29:1-33. doi: 10.1080/09553002.2019.1625490. [Epub ahead of print]


Acetyl-11-keto-β-boswellic acid triggers premature senescence via induction of DNA damage accompanied by impairment of DNA repair genes in hepatocellular carcinoma cells in vitro and in vivo.

Wang S, Wang H, Sun B, Li D, Wu J, Li J, Tian X, Qin C, Chang H, Liu Y.

Fundam Clin Pharmacol. 2019 May 29. doi: 10.1111/fcp.12488. [Epub ahead of print]


Enhancement of Heat Dissipation in Ultraviolet Light-Emitting Diodes by a Vertically Oriented Graphene Nanowall Buffer Layer.

Ci H, Chang H, Wang R, Wei T, Wang Y, Chen Z, Sun Y, Dou Z, Liu Z, Li J, Gao P, Liu Z.

Adv Mater. 2019 May 29:e1901624. doi: 10.1002/adma.201901624. [Epub ahead of print]


Human leukocyte antigen associations in postural tachycardia syndrome.

Shin YW, Moon J, Kim TJ, Kim DY, Chang H, Jun JS, Lee ST, Jung KH, Park KI, Jung KY, Kim M, Lee SK, Chu K.

Ann Clin Transl Neurol. 2019 Apr 4;6(5):962-967. doi: 10.1002/acn3.766. eCollection 2019 May.


The prognostic significance of PD-L1 and PD-1 expression in patients with nasopharyngeal carcinoma: a systematic review and meta-analysis.

Huang ZL, Liu S, Wang GN, Zheng SH, Ding SR, Tao YL, Chen C, Liu SR, Yang X, Chang H, Wang XH, Xia YF.

Cancer Cell Int. 2019 May 22;19:141. doi: 10.1186/s12935-019-0863-5. eCollection 2019.


The Risk of Hospitalization for Motor Vehicle Accident Injury in Narcolepsy and the Benefits of Stimulant Use: A Nationwide Cohort Study in Taiwan.

Tzeng NS, Hsing SC, Chung CH, Chang HA, Kao YC, Mao WC, Yang CCH, Kuo TBJ, Chen TY, Chien WC.

J Clin Sleep Med. 2019 May 24. pii: jc-18-00637. [Epub ahead of print]


[Evidence-Based Clinical Practice Guidelines: Delirium Management in Hospitalized Older Patients].

Chang HW, Hu FW, Yueh FR, Chang YJ.

Hu Li Za Zhi. 2019 Jun;66(3):72-82. doi: 10.6224/JN.201906_66(3).09. Chinese.


HiChIRP reveals RNA-associated chromosome conformation.

Mumbach MR, Granja JM, Flynn RA, Roake CM, Satpathy AT, Rubin AJ, Qi Y, Jiang Z, Shams S, Louie BH, Guo JK, Gennert DG, Corces MR, Khavari PA, Atianand MK, Artandi SE, Fitzgerald KA, Greenleaf WJ, Chang HY.

Nat Methods. 2019 Jun;16(6):489-492. doi: 10.1038/s41592-019-0407-x. Epub 2019 May 27.


Longitudinal study of the relationship between sleep duration and hypertension in Chinese adult residents (CHNS 2004-2011).

Feng X, Liu Q, Li Y, Zhao F, Chang H, Lyu J.

Sleep Med. 2019 Jun;58:88-92. doi: 10.1016/j.sleep.2019.01.006. Epub 2019 Jan 15.


T helper lymphocytes of chronic inflammation are maintained by fatty acid oxidation and adapt to it through Twist1.

Hradilkova K, Maschmeyer P, Westendorf K, Schliemann H, Husak O, von Stuckrad SL, Kallinich T, Minden K, Durek P, Grün JR, Chang HD, Radbruch A.

Arthritis Rheumatol. 2019 May 27. doi: 10.1002/art.40939. [Epub ahead of print]


Risk Factor Analysis of Extended Opioid Use after Coronary Artery Bypass Grafting: A Clinical Data Warehouse-Based Study.

Kang J, Kim JH, Lee KH, Lee WS, Chang HW, Kim JS, Park KH, Lim C.

Healthc Inform Res. 2019 Apr;25(2):124-130. doi: 10.4258/hir.2019.25.2.124. Epub 2019 Apr 30.

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