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Items: 1 to 50 of 320

1.

Total Synthesis of Desmethyl Jahanyne and Its Lipo-Tetrapeptide Conjugates Derived from Parent Skeleton as BCL-2-Mediated Apoptosis-Inducing Agents.

Kallepu S, Kavitha M, Yeeravalli R, Manupati K, Jadav SS, Das A, Mainkar PS, Chandrasekhar S.

ACS Omega. 2018 Jan 31;3(1):63-75. doi: 10.1021/acsomega.7b01634. Epub 2018 Jan 4.

2.

Treating the Elderly with Science and Dignity.

Chandrasekhar SS.

Otolaryngol Clin North Am. 2018 Aug;51(4):xv-xvi. doi: 10.1016/j.otc.2018.04.003. Epub 2018 May 17. No abstract available.

PMID:
29779615
3.

On line rates, information rates, and spectral efficiencies in probabilistically shaped QAM systems.

Cho J, Chen X, Chandrasekhar S, Winzer P.

Opt Express. 2018 Apr 16;26(8):9784-9791. doi: 10.1364/OE.26.009784.

PMID:
29715924
4.

A comparative In vivo efficacy of three spiral techniques versus incremental technique in obturating primary teeth.

Chandrasekhar S, Prasad MG, Radhakrishna AN, Saujanya K, Raviteja NVK, Deepthi B, Ramakrishna J.

J Indian Soc Pedod Prev Dent. 2018 Jan-Mar;36(1):71-75. doi: 10.4103/JISPPD.JISPPD_365_16.

5.

Otolaryngology Around the World.

Chandrasekhar SS.

Otolaryngol Clin North Am. 2018 Jun;51(3):xvii-xviii. doi: 10.1016/j.otc.2018.02.003. Epub 2018 Mar 21. No abstract available.

PMID:
29571560
6.

Women of the American Otological Society.

Alyono JC, Jackler RK, Chandrasekhar SS.

Otol Neurotol. 2018 Apr;39(4S Suppl 1):S69-S80. doi: 10.1097/MAO.0000000000001707.

PMID:
29533377
7.

Fiber nonlinearity mitigation of WDM-PDM QPSK/16-QAM signals using fiber-optic parametric amplifiers based multiple optical phase conjugations.

Hu H, Jopson RM, Gnauck AH, Randel S, Chandrasekhar S.

Opt Express. 2017 Feb 6;25(3):1618-1628. doi: 10.1364/OE.25.001618.

PMID:
29519016
8.

Equality Promotes Wellness.

Chandrasekhar SS.

Otolaryngol Head Neck Surg. 2018 Jun;158(6):981-982. doi: 10.1177/0194599818760260. Epub 2018 Feb 27.

PMID:
29484918
9.

Probabilistically shaped PDM 4096-QAM transmission over up to 200 km of fiber using standard intradyne detection.

Olsson SLI, Cho J, Chandrasekhar S, Chen X, Winzer PJ, Makovejs S.

Opt Express. 2018 Feb 19;26(4):4522-4530. doi: 10.1364/OE.26.004522.

PMID:
29475302
10.

Syntheses of 2-Aroyl Benzofurans through Cascade Annulation on Arynes.

Gouthami P, Chavan LN, Chegondi R, Chandrasekhar S.

J Org Chem. 2018 Mar 16;83(6):3325-3332. doi: 10.1021/acs.joc.8b00360. Epub 2018 Mar 1.

PMID:
29474090
11.

International consensus (ICON) on treatment of sudden sensorineural hearing loss.

Marx M, Younes E, Chandrasekhar SS, Ito J, Plontke S, O'Leary S, Sterkers O.

Eur Ann Otorhinolaryngol Head Neck Dis. 2018 Feb;135(1S):S23-S28. doi: 10.1016/j.anorl.2017.12.011. Epub 2018 Feb 1.

PMID:
29396226
12.

A Significant Treatable Cause of Hearing Loss in Our Time.

Chandrasekhar SS.

Otolaryngol Clin North Am. 2018 Apr;51(2):xv-xvi. doi: 10.1016/j.otc.2017.12.002. Epub 2018 Jan 17. No abstract available.

PMID:
29352571
13.

Synthetic Strategy toward the Pentacyclic Core of Melodinus Alkaloids.

Goli N, Kallepu S, Mainkar PS, Lakshmi JK, Chegondi R, Chandrasekhar S.

J Org Chem. 2018 Feb 16;83(4):2244-2249. doi: 10.1021/acs.joc.7b03138. Epub 2018 Jan 26.

PMID:
29338221
14.

Multidisciplinary Approach to Vascular Anomalies Maximizes Outcomes.

Chandrasekhar SS.

Otolaryngol Clin North Am. 2018 Feb;51(1):xv-xvi. doi: 10.1016/j.otc.2017.09.023. No abstract available.

PMID:
29217072
15.

Allergy as Part of the Unified Otolaryngologic Practice.

Chandrasekhar SS.

Otolaryngol Clin North Am. 2017 Dec;50(6):xv-xvi. doi: 10.1016/j.otc.2017.09.022. No abstract available.

PMID:
29103455
16.

Household food insecurity and children's dietary diversity and nutrition in India. Evidence from the comprehensive nutrition survey in Maharashtra.

Chandrasekhar S, Aguayo VM, Krishna V, Nair R.

Matern Child Nutr. 2017 Oct;13 Suppl 2. doi: 10.1111/mcn.12447.

PMID:
29032621
17.

See One, Do One, Teach One: No More.

Chandrasekhar SS.

Otolaryngol Clin North Am. 2017 Oct;50(5):xv-xvi. doi: 10.1016/j.otc.2017.07.002. Epub 2017 Aug 2. No abstract available.

PMID:
28778352
18.

More than Just Mitoses: Complete Care of the Patient with Head and Neck Cancer.

Chandrasekhar SS.

Otolaryngol Clin North Am. 2017 Aug;50(4):xv-xvi. doi: 10.1016/j.otc.2017.06.001. No abstract available.

PMID:
28755709
19.

Pioneering Strategies for Relieving Dental Anxiety in Hearing Impaired Children: a Randomized Controlled Clinical Study.

Chandrasekhar S, Madu GP, Ambati NR, Suravarapu PR, Uppu K, Bolla D.

J Dent (Shiraz). 2017 Jun;18(2):112-117.

20.

Analgesic and anti-inflammatory properties of novel, selective, and potent EP4 receptor antagonists.

Chandrasekhar S, Yu XP, Harvey AK, Oskins JL, Lin C, Wang X, Blanco MJ, Fisher MJ, Kuklish SL, Schiffler MA, Vetman T, Warshawsky AM, York JS, Bendele AM, Chambers MG.

Pharmacol Res Perspect. 2017 May 14;5(3):e00316. doi: 10.1002/prp2.316. eCollection 2017 Jun.

21.

Comparative Evaluation of Two Bis-GMA Based Orthodontic Bonding Adhesives - A Randomized Clinical Trial.

Samantha C, Sundari S, Chandrasekhar S, Sivamurty G, Dinesh S.

J Clin Diagn Res. 2017 Apr;11(4):ZC40-ZC44. doi: 10.7860/JCDR/2017/16716.9665. Epub 2017 Apr 1.

22.

Association of Gender With Financial Relationships Between Industry and Academic Otolaryngologists.

Eloy JA, Bobian M, Svider PF, Culver A, Siegel B, Gray ST, Baredes S, Chandrasekhar SS, Folbe AJ.

JAMA Otolaryngol Head Neck Surg. 2017 Aug 1;143(8):796-802. doi: 10.1001/jamaoto.2017.0276.

PMID:
28570741
23.

Harnessing Technology at the Edges of Otolaryngology.

Chandrasekhar SS.

Otolaryngol Clin North Am. 2017 Jun;50(3):xvii-xviii. doi: 10.1016/j.otc.2017.03.003. No abstract available.

PMID:
28502533
24.

Total Synthesis of Lamellarin D Trimethyl Ether, Lamellarin D, and Lamellarin H.

Lade DM, Pawar AB, Mainkar PS, Chandrasekhar S.

J Org Chem. 2017 May 5;82(9):4998-5004. doi: 10.1021/acs.joc.7b00636. Epub 2017 Apr 24.

PMID:
28421766
25.

In response to Endoscopic-assisted transmastoid decompression of petrous apex cholesterol granuloma.

Chandrasekhar SS, Carlton DA, Iloreta AMC.

Laryngoscope. 2017 Jun;127(6):E211. doi: 10.1002/lary.26588. Epub 2017 Apr 13. No abstract available.

PMID:
28407254
26.

Results of a phase I-II study of adjuvant concurrent carboplatin and accelerated radiotherapy for triple negative breast cancer.

Formenti SC, Golden EB, Goldberg JD, Li X, Taff J, Fenton-Kerimian MB, Chandrasekhar S, Demaria S, Novik Y.

Oncoimmunology. 2016 Dec 27;6(3):e1274479. doi: 10.1080/2162402X.2016.1274479. eCollection 2017.

27.

Applicability of Demirjian's Method and Modified Cameriere's Methods for Dental Age Assessment in Children.

Pratyusha K, Prasad MG, Radhakrishna AN, Saujanya K, Raviteja NV, Chandrasekhar S.

J Clin Diagn Res. 2017 Feb;11(2):ZC40-ZC43. doi: 10.7860/JCDR/2017/21474.9342. Epub 2017 Feb 1.

28.

Expanding the tetrahydroquinoline pharmacophore.

Goli N, Mainkar PS, Kotapalli SS, K T, Ummanni R, Chandrasekhar S.

Bioorg Med Chem Lett. 2017 Apr 15;27(8):1714-1720. doi: 10.1016/j.bmcl.2017.02.077. Epub 2017 Mar 6.

PMID:
28318941
29.

Anterior Skull Base Malignancies-The Otolaryngologist's Contribution.

Chandrasekhar SS.

Otolaryngol Clin North Am. 2017 Apr;50(2):xix-xx. doi: 10.1016/j.otc.2017.01.002. No abstract available.

PMID:
28314408
30.

In reference to Otolaryngology workforce analysis.

Anne S, Chandrasekhar SS.

Laryngoscope. 2017 Aug;127(8):E291-E292. doi: 10.1002/lary.26502. Epub 2017 Feb 21. No abstract available.

PMID:
28220504
31.

Anesthetic considerations for labor and delivery in women with cerebrospinal fluid shunts.

Rajagopalan S, Gopinath S, Trinh VT, Chandrasekhar S.

Int J Obstet Anesth. 2017 May;30:23-29. doi: 10.1016/j.ijoa.2017.01.005. Epub 2017 Jan 16. Review.

PMID:
28202311
32.

Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1.

Partridge KM, Antonysamy S, Bhattachar SN, Chandrasekhar S, Fisher MJ, Fretland A, Gooding K, Harvey A, Hughes NE, Kuklish SL, Luz JG, Manninen PR, McGee JE, Mudra DR, Navarro A, Norman BH, Quimby SJ, Schiffler MA, Sloan AV, Warshawsky AM, Weller JM, York JS, Yu XP.

Bioorg Med Chem Lett. 2017 Mar 15;27(6):1478-1483. doi: 10.1016/j.bmcl.2016.11.011. Epub 2016 Nov 7.

PMID:
28190634
33.

Chronic Rhinosinusitis: A "Simple" Complex Condition.

Chandrasekhar SS.

Otolaryngol Clin North Am. 2017 Feb;50(1):xv-xvi. doi: 10.1016/j.otc.2016.10.003. No abstract available.

PMID:
27888919
34.

Airway management for cesarean delivery performed under general anesthesia.

Rajagopalan S, Suresh M, Clark SL, Serratos B, Chandrasekhar S.

Int J Obstet Anesth. 2017 Feb;29:64-69. doi: 10.1016/j.ijoa.2016.10.007. Epub 2016 Oct 27.

PMID:
27884665
35.

Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design.

Jones SB, Pfeifer LA, Bleisch TJ, Beauchamp TJ, Durbin JD, Klimkowski VJ, Hughes NE, Rito CJ, Dao Y, Gruber JM, Bui H, Chambers MG, Chandrasekhar S, Lin C, McCann DJ, Mudra DR, Oskins JL, Swearingen CA, Thirunavukkarasu K, Norman BH.

ACS Med Chem Lett. 2016 Aug 2;7(9):857-61. doi: 10.1021/acsmedchemlett.6b00207. eCollection 2016 Sep 8.

36.

Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors.

Kuklish SL, Antonysamy S, Bhattachar SN, Chandrasekhar S, Fisher MJ, Fretland AJ, Gooding K, Harvey A, Hughes NE, Luz JG, Manninen PR, McGee JE, Navarro A, Norman BH, Partridge KM, Quimby SJ, Schiffler MA, Sloan AV, Warshawsky AM, York JS, Yu XP.

Bioorg Med Chem Lett. 2016 Oct 1;26(19):4824-4828. doi: 10.1016/j.bmcl.2016.08.023. Epub 2016 Aug 10.

PMID:
27554445
37.

128-Gb/s 100-km transmission with direct detection using silicon photonic Stokes vector receiver and I/Q modulator.

Dong P, Chen X, Kim K, Chandrasekhar S, Chen YK, Sinsky JH.

Opt Express. 2016 Jun 27;24(13):14208-14. doi: 10.1364/OE.24.014208.

PMID:
27410578
38.

Endoscopic-assisted transmastoid decompression of petrous apex cholesterol granuloma.

Carlton DA, Iloreta AM, Chandrasekhar SS.

Laryngoscope. 2017 Feb;127(2):496-499. doi: 10.1002/lary.26100. Epub 2016 Jul 7. No abstract available.

PMID:
27385034
39.

Oral health status and treatment needs among 10126 school children in West Godavari district, Andhra Pradesh, India.

Prasad MG, Radhakrishna AN, Kambalimath HV, Chandrasekhar S, Deepthi B, Ramakrishna J.

J Int Soc Prev Community Dent. 2016 May-Jun;6(3):213-8. doi: 10.4103/2231-0762.183102. Epub 2016 May 30.

40.

Expanding Diversity without Protecting Groups: (+)-Sclareolide to Indolosesquiterpene Alkaloid Mycoleptodiscin A and Analogues.

Nagaraju K, Chegondi R, Chandrasekhar S.

Org Lett. 2016 Jun 3;18(11):2684-7. doi: 10.1021/acs.orglett.6b01145. Epub 2016 May 16.

PMID:
27181938
41.

Formal Total Synthesis of (±)-Cephalotaxine and Congeners via Aryne Insertion Reaction.

Gouthami P, Chegondi R, Chandrasekhar S.

Org Lett. 2016 May 6;18(9):2044-6. doi: 10.1021/acs.orglett.6b00659. Epub 2016 Apr 12.

PMID:
27070197
42.

Identification and biological activity of 6-alkyl-substituted 3-methyl-pyridine-2-carbonyl amino dimethyl-benzoic acid EP4 antagonists.

Blanco MJ, Vetman T, Chandrasekhar S, Fisher MJ, Harvey A, Kuklish SL, Chambers M, Lin C, Mudra D, Oskins J, Wang XS, Yu XP, Warshawsky AM.

Bioorg Med Chem Lett. 2016 May 1;26(9):2303-7. doi: 10.1016/j.bmcl.2016.03.041. Epub 2016 Mar 12.

PMID:
27020304
43.

Insertion of N-Tosylacetimidates/Acetimidamides onto Arynes via [2 + 2] Cycloaddition.

Kranthikumar R, Chegondi R, Chandrasekhar S.

J Org Chem. 2016 Mar 18;81(6):2451-9. doi: 10.1021/acs.joc.5b02907. Epub 2016 Mar 10.

PMID:
26930224
44.

Thiol-Disulfide Exchange in Human Growth Hormone.

Chandrasekhar S, Moorthy BS, Xie R, Topp EM.

Pharm Res. 2016 Jun;33(6):1370-82. doi: 10.1007/s11095-016-1879-3. Epub 2016 Feb 17.

45.

Discovery of potent aryl-substituted 3-[(3-methylpyridine-2-carbonyl) amino]-2,4-dimethyl-benzoic acid EP4 antagonists with improved pharmacokinetic profile.

Blanco MJ, Vetman T, Chandrasekhar S, Fisher MJ, Harvey A, Chambers M, Lin C, Mudra D, Oskins J, Wang XS, Yu XP, Warshawsky AM.

Bioorg Med Chem Lett. 2016 Feb 1;26(3):931-935. doi: 10.1016/j.bmcl.2015.12.057. Epub 2015 Dec 25.

PMID:
26764191
46.

Identification and Characterization of Novel Microsomal Prostaglandin E Synthase-1 Inhibitors for Analgesia.

Chandrasekhar S, Harvey AK, Yu XP, Chambers MG, Oskins JL, Lin C, Seng TW, Thibodeaux SJ, Norman BH, Hughes NE, Schiffler MA, Fisher MJ.

J Pharmacol Exp Ther. 2016 Mar;356(3):635-44. doi: 10.1124/jpet.115.228932. Epub 2016 Jan 6.

47.

Synthesis and biological evaluation of 5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one structural derivatives as anti-cancer and apoptosis inducing agents.

Praveen Kumar C, Reddy TS, Mainkar PS, Bansal V, Shukla R, Chandrasekhar S, Hügel HM.

Eur J Med Chem. 2016 Jan 27;108:674-686. doi: 10.1016/j.ejmech.2015.12.007. Epub 2015 Dec 10.

PMID:
26735909
48.

The Ireland-Claisen rearrangement strategy towards the synthesis of the schizophrenia drug, (+)-asenapine.

Anugu RR, Mainkar PS, Sridhar B, Chandrasekhar S.

Org Biomol Chem. 2016 Jan 28;14(4):1332-7. doi: 10.1039/c5ob02047f. Epub 2015 Dec 11.

PMID:
26659332
49.

Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors.

Schiffler MA, Antonysamy S, Bhattachar SN, Campanale KM, Chandrasekhar S, Condon B, Desai PV, Fisher MJ, Groshong C, Harvey A, Hickey MJ, Hughes NE, Jones SA, Kim EJ, Kuklish SL, Luz JG, Norman BH, Rathmell RE, Rizzo JR, Seng TW, Thibodeaux SJ, Woods TA, York JS, Yu XP.

J Med Chem. 2016 Jan 14;59(1):194-205. doi: 10.1021/acs.jmedchem.5b01249. Epub 2015 Dec 18.

PMID:
26653180
50.

Discovery of substituted-2,4-dimethyl-(naphthalene-4-carbonyl)amino-benzoic acid as potent and selective EP4 antagonists.

Blanco MJ, Vetman T, Chandrasekhar S, Fisher MJ, Harvey A, Mudra D, Wang XS, Yu XP, Schiffler MA, Warshawsky AM.

Bioorg Med Chem Lett. 2016 Jan 1;26(1):105-9. doi: 10.1016/j.bmcl.2015.11.023. Epub 2015 Nov 10.

PMID:
26608552

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