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Items: 14


Molecular basis of microhomology-mediated end-joining by purified full-length Polθ.

Black SJ, Ozdemir AY, Kashkina E, Kent T, Rusanov T, Ristic D, Shin Y, Suma A, Hoang T, Chandramouly G, Siddique LA, Borisonnik N, Sullivan-Reed K, Mallon JS, Skorski T, Carnevale V, Murakami KS, Wyman C, Pomerantz RT.

Nat Commun. 2019 Sep 27;10(1):4423. doi: 10.1038/s41467-019-12272-9.


Connexin 43 maintains tissue polarity and regulates mitotic spindle orientation in the breast epithelium.

Bazzoun D, Adissu HA, Wang L, Urazaev A, Tenvooren I, Fostok SF, Chittiboyina S, Sturgis J, Hodges K, Chandramouly G, Vidi PA, Talhouk RS, Lelièvre SA.

J Cell Sci. 2019 May 16;132(10). pii: jcs223313. doi: 10.1242/jcs.223313.


How RNA transcripts coordinate DNA recombination and repair.

McDevitt S, Rusanov T, Kent T, Chandramouly G, Pomerantz RT.

Nat Commun. 2018 Mar 15;9(1):1091. doi: 10.1038/s41467-018-03483-7.


Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers.

Chandramouly G, McDevitt S, Sullivan K, Kent T, Luz A, Glickman JF, Andrake M, Skorski T, Pomerantz RT.

Chem Biol. 2015 Nov 19;22(11):1491-1504. doi: 10.1016/j.chembiol.2015.10.003. Epub 2015 Nov 5.


LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.

Liu XS, Chandramouly G, Rass E, Guan Y, Wang G, Hobbs RM, Rajendran A, Xie A, Shah JV, Davis AJ, Scully R, Lunardi A, Pandolfi PP.

Nat Commun. 2015 Oct 8;6:8325. doi: 10.1038/ncomms9325.


Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ.

Kent T, Chandramouly G, McDevitt SM, Ozdemir AY, Pomerantz RT.

Nat Struct Mol Biol. 2015 Mar;22(3):230-7. doi: 10.1038/nsmb.2961. Epub 2015 Feb 2.


BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks.

Willis NA, Chandramouly G, Huang B, Kwok A, Follonier C, Deng C, Scully R.

Nature. 2014 Jun 26;510(7506):556-9. doi: 10.1038/nature13295. Epub 2014 Apr 28.


BRCA1 and CtIP suppress long-tract gene conversion between sister chromatids.

Chandramouly G, Kwok A, Huang B, Willis NA, Xie A, Scully R.

Nat Commun. 2013;4:2404. doi: 10.1038/ncomms3404.


Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells.

Rass E, Chandramouly G, Zha S, Alt FW, Xie A.

J Biol Chem. 2013 Mar 8;288(10):7086-95. doi: 10.1074/jbc.M112.445825. Epub 2013 Jan 26.


Interconnected contribution of tissue morphogenesis and the nuclear protein NuMA to the DNA damage response.

Vidi PA, Chandramouly G, Gray M, Wang L, Liu E, Kim JJ, Roukos V, Bissell MJ, Moghe PV, Lelièvre SA.

J Cell Sci. 2012 Jan 15;125(Pt 2):350-61. doi: 10.1242/jcs.089177. Epub 2012 Feb 13.


A protective role for BRCA2 at stalled replication forks.

Chandramouly G, Willis NA, Scully R.

Breast Cancer Res. 2011 Sep 7;13(5):314. doi: 10.1186/bcr2918.


H2AX post-translational modifications in the ionizing radiation response and homologous recombination.

Xie A, Odate S, Chandramouly G, Scully R.

Cell Cycle. 2010 Sep 1;9(17):3602-10. doi: 10.4161/cc.9.17.12884. Epub 2010 Sep 1.


XRCC2 and XRCC3 regulate the balance between short- and long-tract gene conversions between sister chromatids.

Nagaraju G, Hartlerode A, Kwok A, Chandramouly G, Scully R.

Mol Cell Biol. 2009 Aug;29(15):4283-94. doi: 10.1128/MCB.01406-08. Epub 2009 May 26.


The control of tissue architecture over nuclear organization is crucial for epithelial cell fate.

Chandramouly G, Abad PC, Knowles DW, Lelièvre SA.

J Cell Sci. 2007 May 1;120(Pt 9):1596-606. Epub 2007 Apr 3.

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