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Items: 30

1.

Poliovirus Receptor (CD155) Expression in Pediatric Brain Tumors Mediates Oncolysis of Medulloblastoma and Pleomorphic Xanthoastrocytoma.

Thompson EM, Brown M, Dobrikova E, Ramaswamy V, Taylor MD, McLendon R, Sanks J, Chandramohan V, Bigner D, Gromeier M.

J Neuropathol Exp Neurol. 2018 Aug 1;77(8):696-702. doi: 10.1093/jnen/nly045.

PMID:
29878245
2.

Sym004-induced EGFR elimination is associated with profound anti-tumor activity in EGFRvIII patient-derived glioblastoma models.

Keir ST, Chandramohan V, Hemphill CD, Grandal MM, Melander MC, Pedersen MW, Horak ID, Kragh M, Desjardins A, Friedman HS, Bigner DD.

J Neurooncol. 2018 Jul;138(3):489-498. doi: 10.1007/s11060-018-2832-6. Epub 2018 Mar 21.

3.

T-Cell Exhaustion Signatures Vary with Tumor Type and Are Severe in Glioblastoma.

Woroniecka K, Chongsathidkiet P, Rhodin K, Kemeny H, Dechant C, Farber SH, Elsamadicy AA, Cui X, Koyama S, Jackson C, Hansen LJ, Johanns TM, Sanchez-Perez L, Chandramohan V, Yu YA, Bigner DD, Giles A, Healy P, Dranoff G, Weinhold KJ, Dunn GP, Fecci PE.

Clin Cancer Res. 2018 Sep 1;24(17):4175-4186. doi: 10.1158/1078-0432.CCR-17-1846. Epub 2018 Feb 7.

PMID:
29437767
4.

Selection of novel affinity-matured human chondroitin sulfate proteoglycan 4 antibody fragments by yeast display.

Yu X, Qu L, Bigner DD, Chandramohan V.

Protein Eng Des Sel. 2017 Sep 1;30(9):639-647. doi: 10.1093/protein/gzx038.

5.

Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen-specific CTLs.

Brown MC, Holl EK, Boczkowski D, Dobrikova E, Mosaheb M, Chandramohan V, Bigner DD, Gromeier M, Nair SK.

Sci Transl Med. 2017 Sep 20;9(408). pii: eaan4220. doi: 10.1126/scitranslmed.aan4220.

6.

Validation of an Immunohistochemistry Assay for Detection of CD155, the Poliovirus Receptor, in Malignant Gliomas.

Chandramohan V, Bryant JD, Piao H, Keir ST, Lipp ES, Lefaivre M, Perkinson K, Bigner DD, Gromeier M, McLendon RE.

Arch Pathol Lab Med. 2017 Dec;141(12):1697-1704. doi: 10.5858/arpa.2016-0580-OA. Epub 2017 Aug 22.

PMID:
28829151
7.

Development and validation of a cell-based fluorescent method for measuring antibody affinity.

Yu X, Pegram CN, Bigner DD, Chandramohan V.

J Immunol Methods. 2017 Mar;442:49-53. doi: 10.1016/j.jim.2016.12.004. Epub 2016 Dec 24.

8.

Production and quality control assessment of a GLP-grade immunotoxin, D2C7-(scdsFv)-PE38KDEL, for a phase I/II clinical trial.

Chandramohan V, Pegram CN, Piao H, Szafranski SE, Kuan CT, Pastan IH, Bigner DD.

Appl Microbiol Biotechnol. 2017 Apr;101(7):2747-2766. doi: 10.1007/s00253-016-8063-x. Epub 2016 Dec 24.

9.

CAR T Cells Targeting Podoplanin Reduce Orthotopic Glioblastomas in Mouse Brains.

Shiina S, Ohno M, Ohka F, Kuramitsu S, Yamamichi A, Kato A, Motomura K, Tanahashi K, Yamamoto T, Watanabe R, Ito I, Senga T, Hamaguchi M, Wakabayashi T, Kaneko MK, Kato Y, Chandramohan V, Bigner DD, Natsume A.

Cancer Immunol Res. 2016 Mar;4(3):259-68. doi: 10.1158/2326-6066.CIR-15-0060. Epub 2016 Jan 28.

10.

Preclinical toxicity evaluation of a novel immunotoxin, D2C7-(scdsFv)-PE38KDEL, administered via intracerebral convection-enhanced delivery in rats.

Bao X, Chandramohan V, Reynolds RP, Norton JN, Wetsel WC, Rodriguiz RM, Aryal DK, McLendon RE, Levin ED, Petry NA, Zalutsky MR, Burnett BK, Kuan CT, Pastan IH, Bigner DD.

Invest New Drugs. 2016 Apr;34(2):149-58. doi: 10.1007/s10637-015-0318-3. Epub 2016 Jan 4.

11.

EGFR/EGFRvIII-targeted immunotoxin therapy for the treatment of glioblastomas via convection-enhanced delivery.

Bao X, Pastan I, Bigner DD, Chandramohan V.

Receptors Clin Investig. 2016;3(4). pii: e1430. doi: 10.14800/rci.1430.

12.

Evaluating Andrographolide as a Potent Inhibitor of NS3-4A Protease and Its Drug-Resistant Mutants Using In Silico Approaches.

Chandramohan V, Kaphle A, Chekuri M, Gangarudraiah S, Bychapur Siddaiah G.

Adv Virol. 2015;2015:972067. doi: 10.1155/2015/972067. Epub 2015 Oct 26.

13.

Identification of Deleterious SNPs and Their Effects on Structural Level in CHRNA3 Gene.

Chandramohan V, Nagaraju N, Rathod S, Kaphle A, Muddapur U.

Biochem Genet. 2015 Aug;53(7-8):159-68. doi: 10.1007/s10528-015-9676-y. Epub 2015 May 23.

PMID:
26002565
14.

Induction of viral, 7-methyl-guanosine cap-independent translation and oncolysis by mitogen-activated protein kinase-interacting kinase-mediated effects on the serine/arginine-rich protein kinase.

Brown MC, Bryant JD, Dobrikova EY, Shveygert M, Bradrick SS, Chandramohan V, Bigner DD, Gromeier M.

J Virol. 2014 Nov;88(22):13135-48. doi: 10.1128/JVI.01883-14. Epub 2014 Sep 3.

15.
16.

Affinity-matured recombinant immunotoxin targeting gangliosides 3'-isoLM1 and 3',6'-isoLD1 on malignant gliomas.

Piao H, Kuan CT, Chandramohan V, Keir ST, Pegram CN, Bao X, Månsson JE, Pastan IH, Bigner DD.

MAbs. 2013 Sep-Oct;5(5):748-62. doi: 10.4161/mabs.25860. Epub 2013 Jul 25.

17.

Construction of an immunotoxin, D2C7-(scdsFv)-PE38KDEL, targeting EGFRwt and EGFRvIII for brain tumor therapy.

Chandramohan V, Bao X, Keir ST, Pegram CN, Szafranski SE, Piao H, Wikstrand CJ, McLendon RE, Kuan CT, Pastan IH, Bigner DD.

Clin Cancer Res. 2013 Sep 1;19(17):4717-27. doi: 10.1158/1078-0432.CCR-12-3891. Epub 2013 Jul 15.

18.

Antibody, T-cell and dendritic cell immunotherapy for malignant brain tumors.

Chandramohan V, Mitchell DA, Johnson LA, Sampson JH, Bigner DD.

Future Oncol. 2013 Jul;9(7):977-90. doi: 10.2217/fon.13.47. Review.

19.

Primary squamous cell carcinoma of breast presenting as a cystic mass.

Sheela CS, Ramakant P, Shah G, Chandramohan V, Abraham D, Paul MJ.

J Postgrad Med. 2013 Apr-Jun;59(2):155-6. doi: 10.4103/0022-3859.113839. No abstract available.

20.

Posterior reversible encephalopathy syndrome in a child with autoimmune lymphoproliferative syndrome: Case report and review of literature.

Chandramohan V, Nagarajan VP, Sathyamoorthi MS, Kumar S, Shanmugasundaram C, Periakaruppan G, Scott JX.

J Pediatr Neurosci. 2012 Sep;7(3):221-4. doi: 10.4103/1817-1745.106486.

21.

Recombinant anti-podoplanin (NZ-1) immunotoxin for the treatment of malignant brain tumors.

Chandramohan V, Bao X, Kato Kaneko M, Kato Y, Keir ST, Szafranski SE, Kuan CT, Pastan IH, Bigner DD.

Int J Cancer. 2013 May 15;132(10):2339-48. doi: 10.1002/ijc.27919. Epub 2012 Nov 23.

22.

Toxin-based targeted therapy for malignant brain tumors.

Chandramohan V, Sampson JH, Pastan I, Bigner DD.

Clin Dev Immunol. 2012;2012:480429. doi: 10.1155/2012/480429. Epub 2012 Feb 9. Review.

23.

Evaluation of anti-podoplanin rat monoclonal antibody NZ-1 for targeting malignant gliomas.

Kato Y, Vaidyanathan G, Kaneko MK, Mishima K, Srivastava N, Chandramohan V, Pegram C, Keir ST, Kuan CT, Bigner DD, Zalutsky MR.

Nucl Med Biol. 2010 Oct;37(7):785-94. doi: 10.1016/j.nucmedbio.2010.03.010.

24.

A young male heart transplant recipient who developed CKD due to cyclosporine therapy after a decade.

Chandramohan V, Abraham G, Matthew M, Mullassery A, Thirumoorthy K.

J Assoc Physicians India. 2010 Mar;58:190-2.

PMID:
20848820
25.

GMab-1, a high-affinity anti-3'-isoLM1/3',6'-isoLD1 IgG monoclonal antibody, raised in lacto-series ganglioside-defective knockout mice.

Kato Y, Kuan CT, Chang J, Kaneko MK, Ayriss J, Piao H, Chandramohan V, Pegram C, McLendon RE, Fredman P, Månsson JE, Bigner DD.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):750-5. doi: 10.1016/j.bbrc.2009.11.132. Epub 2009 Nov 26.

26.

Fracture of the penis: a radiological or clinical diagnosis? A case series and literature review.

Agarwal MM, Singh SK, Sharma DK, Ranjan P, Kumar S, Chandramohan V, Gupta N, Acharya NC, Bhalla V, Mavuduru R, Mandal AK.

Can J Urol. 2009 Apr;16(2):4568-75. Review.

PMID:
19364429
27.

c-Myc represses FOXO3a-mediated transcription of the gene encoding the p27(Kip1) cyclin dependent kinase inhibitor.

Chandramohan V, Mineva ND, Burke B, Jeay S, Wu M, Shen J, Yang W, Hann SR, Sonenshein GE.

J Cell Biochem. 2008 Aug 15;104(6):2091-106. doi: 10.1002/jcb.21765.

PMID:
18393360
28.

Primary retrovesical hydatidosis causing chronic renal failure.

Singh SK, Wadhwa P, Chandramohan V.

Int J Urol. 2006 Jan;13(1):76-9.

29.
30.

Effect of a physician-directed educational campaign on performance of proper diabetic foot exams in an outpatient setting.

O'Brien KE, Chandramohan V, Nelson DA, Fischer JR Jr, Stevens G, Poremba JA.

J Gen Intern Med. 2003 Apr;18(4):258-65.

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