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The Membrane-Active Phytopeptide Cycloviolacin O2 Simultaneously Targets HIV-1-infected Cells and Infectious Viral Particles to Potentiate the Efficacy of Antiretroviral Drugs.

Gerlach SL, Chandra PK, Roy U, Gunasekera S, Göransson U, Wimley WC, Braun SE, Mondal D.

Medicines (Basel). 2019 Feb 28;6(1). pii: E33. doi: 10.3390/medicines6010033.


Mesenchymal stem cells are attracted to latent HIV-1-infected cells and enable virus reactivation via a non-canonical PI3K-NFκB signaling pathway.

Chandra PK, Gerlach SL, Wu C, Khurana N, Swientoniewski LT, Abdel-Mageed AB, Li J, Braun SE, Mondal D.

Sci Rep. 2018 Oct 2;8(1):14702. doi: 10.1038/s41598-018-32657-y.


Interferon-alpha-induced hepatitis C virus clearance restores p53 tumor suppressor more than direct-acting antivirals.

Aydin Y, Chatterjee A, Chandra PK, Chava S, Chen W, Tandon A, Dash A, Chedid M, Moehlen MW, Regenstein F, Balart LA, Cohen A, Lu H, Wu T, Dash S.

Hepatol Commun. 2017 Mar 28;1(3):256-269. doi: 10.1002/hep4.1025. eCollection 2017 May.


Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancer.

Khurana N, Kim H, Chandra PK, Talwar S, Sharma P, Abdel-Mageed AB, Sikka SC, Mondal D.

Oncol Rep. 2017 Nov;38(5):2774-2786. doi: 10.3892/or.2017.5932. Epub 2017 Aug 30.


Chaperone-mediated autophagy compensates for impaired macroautophagy in the cirrhotic liver to promote hepatocellular carcinoma.

Chava S, Lee C, Aydin Y, Chandra PK, Dash A, Chedid M, Thung SN, Moroz K, Wu T, Nayak NC, Dash S.

Oncotarget. 2017 Jun 20;8(25):40019-40036. doi: 10.18632/oncotarget.16685.


Sulforaphane increases the efficacy of anti-androgens by rapidly decreasing androgen receptor levels in prostate cancer cells.

Khurana N, Talwar S, Chandra PK, Sharma P, Abdel-Mageed AB, Mondal D, Sikka SC.

Int J Oncol. 2016 Oct;49(4):1609-19. doi: 10.3892/ijo.2016.3641. Epub 2016 Aug 2.


Hepatitis C Virus Infection Induces Autophagy as a Prosurvival Mechanism to Alleviate Hepatic ER-Stress Response.

Dash S, Chava S, Aydin Y, Chandra PK, Ferraris P, Chen W, Balart LA, Wu T, Garry RF.

Viruses. 2016 May 23;8(5). pii: E150. doi: 10.3390/v8050150. Review.


Autophagy in hepatocellular carcinomas: from pathophysiology to therapeutic response.

Dash S, Chava S, Chandra PK, Aydin Y, Balart LA, Wu T.

Hepat Med. 2016 Feb 22;8:9-20. doi: 10.2147/HMER.S63700. eCollection 2016. Review.


Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-λ Expression.

Ferraris P, Chandra PK, Panigrahi R, Aboulnasr F, Chava S, Kurt R, Pawlotsky JM, Wilkens L, Osterlund P, Hartmann R, Balart LA, Wu T, Dash S.

Am J Pathol. 2016 Apr;186(4):938-51. doi: 10.1016/j.ajpath.2015.11.027. Epub 2016 Feb 16.


Chromosomal microarray provides enhanced targetable gene aberration detection when paired with next generation sequencing panel in profiling lung and colorectal tumors.

Mukherjee S, Ma Z, Wheeler S, Sathanoori M, Coldren C, Prescott JL, Kozyr N, Bouzyk M, Correll M, Ho H, Chandra PK, Lennon PA.

Cancer Genet. 2016 Apr;209(4):119-29. doi: 10.1016/j.cancergen.2015.12.011. Epub 2016 Jan 6.


Tripping on TRIB3 at the junction of health, metabolic dysfunction and cancer.

Mondal D, Mathur A, Chandra PK.

Biochimie. 2016 May;124:34-52. doi: 10.1016/j.biochi.2016.02.005. Epub 2016 Feb 6. Review.


IFN-λ Inhibits MiR-122 Transcription through a Stat3-HNF4α Inflammatory Feedback Loop in an IFN-α Resistant HCV Cell Culture System.

Aboulnasr F, Hazari S, Nayak S, Chandra PK, Panigrahi R, Ferraris P, Chava S, Kurt R, Song K, Dash A, Balart LA, Garry RF, Wu T, Dash S.

PLoS One. 2015 Dec 11;10(12):e0141655. doi: 10.1371/journal.pone.0141655. eCollection 2015.


Peroxide-based oxygen generating topical wound dressing for enhancing healing of dermal wounds.

Chandra PK, Ross CL, Smith LC, Jeong SS, Kim J, Yoo JJ, Harrison BS.

Wound Repair Regen. 2015 Nov-Dec;23(6):830-41. doi: 10.1111/wrr.12324. Epub 2015 Nov 4.


Chaperone-Mediated Autophagy Targets IFNAR1 for Lysosomal Degradation in Free Fatty Acid Treated HCV Cell Culture.

Kurt R, Chandra PK, Aboulnasr F, Panigrahi R, Ferraris P, Aydin Y, Reiss K, Wu T, Balart LA, Dash S.

PLoS One. 2015 May 11;10(5):e0125962. doi: 10.1371/journal.pone.0125962. eCollection 2015.


Contribution of Beta-HPV Infection and UV Damage to Rapid-Onset Cutaneous Squamous Cell Carcinoma during BRAF-Inhibition Therapy.

Cohen DN, Lawson SK, Shaver AC, Du L, Nguyen HP, He Q, Johnson DB, Lumbang WA, Moody BR, Prescott JL, Chandra PK, Boyd AS, Zwerner JP, Robbins JB, Tyring SK, Rady PL, Chappell JD, Shyr Y, Infante JR, Sosman JA.

Clin Cancer Res. 2015 Jun 1;21(11):2624-34. doi: 10.1158/1078-0432.CCR-14-2667. Epub 2015 Feb 27.


Persistent hepatitis C virus infection impairs ribavirin antiviral activity through clathrin-mediated trafficking of equilibrative nucleoside transporter 1.

Panigrahi R, Chandra PK, Ferraris P, Kurt R, Song K, Garry RF, Reiss K, Coe IR, Furihata T, Balart LA, Wu T, Dash S.

J Virol. 2015 Jan;89(1):626-42. doi: 10.1128/JVI.02492-14. Epub 2014 Oct 22.


Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis.

Chandra PK, Gunduz F, Hazari S, Kurt R, Panigrahi R, Poat B, Bruce D, Cohen AJ, Bohorquez HE, Carmody I, Loss G, Balart LA, Wu T, Dash S.

PLoS One. 2014 Sep 29;9(9):e108616. doi: 10.1371/journal.pone.0108616. eCollection 2014. Erratum in: PLoS One. 2014;9(11):e114456. Behorquez, Humberto E [corrected to Bohorquez, Humberto E].


Impaired autophagy response in human hepatocellular carcinoma.

Bao L, Chandra PK, Moroz K, Zhang X, Thung SN, Wu T, Dash S.

Exp Mol Pathol. 2014 Apr;96(2):149-54. doi: 10.1016/j.yexmp.2013.12.002. Epub 2013 Dec 23.


Characterization of the occult hepatitis B virus variants circulating among the blood donors from eastern India.

Biswas A, Panigrahi R, Chandra PK, Banerjee A, Datta S, Pal M, Chakraborty S, Bhattacharya P, Chakrabarti S, Chakravarty R.

ScientificWorldJournal. 2013 Nov 4;2013:212704. doi: 10.1155/2013/212704. eCollection 2013.


HCV infection selectively impairs type I but not type III IFN signaling.

Chandra PK, Bao L, Song K, Aboulnasr FM, Baker DP, Shores N, Wimley WC, Liu S, Hagedorn CH, Fuchs SY, Wu T, Balart LA, Dash S.

Am J Pathol. 2014 Jan;184(1):214-29. doi: 10.1016/j.ajpath.2013.10.005. Epub 2013 Nov 9.


Interferon and ribavirin combination treatment synergistically inhibit HCV internal ribosome entry site mediated translation at the level of polyribosome formation.

Panigrahi R, Hazari S, Chandra S, Chandra PK, Datta S, Kurt R, Cameron CE, Huang Z, Zhang H, Garry RF, Balart LA, Dash S.

PLoS One. 2013 Aug 23;8(8):e72791. doi: 10.1371/journal.pone.0072791. eCollection 2013.


Prevention of enamel demineralization during orthodontic treatment: an in vitro comparative study.

Bichu YM, Kamat N, Chandra PK, Kapoor A, Razmus T, Aravind NK.

Orthodontics (Chic.). 2013;14(1):e22-9. doi: 10.11607/ortho.870.


Sex determination potential of permanent maxillary molar widths and cusp diameters in a North Indian population.

Sharma P, Singh T, Kumar P, Chandra PK, Sharma R.

J Orthod Sci. 2013 Apr;2(2):55-60. doi: 10.4103/2278-0203.115090.


Occult HBV infection among anti-HBc positive HIV-infected patients in apex referral centre, Eastern India.

Panigrahi R, Majumder S, Gooptu M, Biswas A, Datta S, Chandra PK, Banerjee A, Chakrabarti S, Bandopadhyay D, De BK, Chakravarty R.

Ann Hepatol. 2012 Nov-Dec;11(6):870-5.


Effect of fluoride mouth rinses on various orthodontic archwire alloys tested by modified bending test: an in vitro study.

Srivastava K, Chandra PK, Kamat N.

Indian J Dent Res. 2012 May-Jun;23(3):433-4. doi: 10.4103/0970-9290.102253.


Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture.

Gunduz F, Aboulnasr FM, Chandra PK, Hazari S, Poat B, Baker DP, Balart LA, Dash S.

Virol J. 2012 Aug 3;9:143. doi: 10.1186/1743-422X-9-143.


Inhibition of hepatitis C virus replication by intracellular delivery of multiple siRNAs by nanosomes.

Chandra PK, Kundu AK, Hazari S, Chandra S, Bao L, Ooms T, Morris GF, Wu T, Mandal TK, Dash S.

Mol Ther. 2012 Sep;20(9):1724-36. doi: 10.1038/mt.2012.107. Epub 2012 May 22.


A rare case of giant cutaneous and extracutaneous haemangiomas.

Nandi M, Mondal RK, Chandra PK.

J Indian Med Assoc. 2011 Jul;109(7):516. No abstract available.


Stability of lyophilized siRNA nanosome formulations.

Kundu AK, Chandra PK, Hazari S, Ledet G, Pramar YV, Dash S, Mandal TK.

Int J Pharm. 2012 Feb 28;423(2):525-34. doi: 10.1016/j.ijpharm.2011.11.040. Epub 2011 Dec 6.


Development and optimization of nanosomal formulations for siRNA delivery to the liver.

Kundu AK, Chandra PK, Hazari S, Pramar YV, Dash S, Mandal TK.

Eur J Pharm Biopharm. 2012 Feb;80(2):257-67. doi: 10.1016/j.ejpb.2011.10.023. Epub 2011 Nov 18.


In vitro resistance to fracture of roots obturated with Resilon or gutta-percha.

Monteiro J, de Ataide Ide N, Chalakkal P, Chandra PK.

J Endod. 2011 Jun;37(6):828-31. doi: 10.1016/j.joen.2011.02.024. Epub 2011 Apr 2.


Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1.

Datta S, Hazari S, Chandra PK, Samara M, Poat B, Gunduz F, Wimley WC, Hauser H, Koster M, Lamaze C, Balart LA, Garry RF, Dash S.

Virol J. 2011 Jul 14;8:351. doi: 10.1186/1743-422X-8-351.


Hepatocellular carcinoma xenograft supports HCV replication: a mouse model for evaluating antivirals.

Hazari S, Hefler HJ, Chandra PK, Poat B, Gunduz F, Ooms T, Wu T, Balart LA, Dash S.

World J Gastroenterol. 2011 Jan 21;17(3):300-12. doi: 10.3748/wjg.v17.i3.300.


Variations in the functional domain of basal core promoter of hepatitis B virus among Eastern Indian patients with prevalence of genotypes A, C, and D among the same ethnic population.

Biswas A, Banerjee A, Chandra PK, Datta S, Panigrahi R, Dutta D, De BK, Pal M, Guha SK, Chakrabarti S, Chakravarty R.

J Med Virol. 2011 Feb;83(2):253-60. doi: 10.1002/jmv.21979.


Neurofibromatosis, pathological fracture and hypervitaminosis-D.

Mondal R, Nandi M, Chandra PK.

Indian Pediatr. 2010 Oct;47(10):881-2.


SH2 modified STAT1 induces HLA-I expression and improves IFN-γ signaling in IFN-α resistant HCV replicon cells.

Poat B, Hazari S, Chandra PK, Gunduz F, Balart LA, Alvarez X, Dash S.

PLoS One. 2010 Sep 30;5(9). pii: e13117. doi: 10.1371/journal.pone.0013117.


Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication.

Poat B, Hazari S, Chandra PK, Gunduz F, Alvarez X, Balart LA, Garry RF, Dash S.

Virol J. 2010 Oct 12;7:265. doi: 10.1186/1743-422X-7-265.


Anti-hepatitis B core antigen testing with detection and characterization of occult hepatitis B virus by an in-house nucleic acid testing among blood donors in Behrampur, Ganjam, Orissa in southeastern India: implications for transfusion.

Panigrahi R, Biswas A, Datta S, Banerjee A, Chandra PK, Mahapatra PK, Patnaik B, Chakrabarti S, Chakravarty R.

Virol J. 2010 Aug 27;7:204. doi: 10.1186/1743-422X-7-204.


Intracytoplasmic stable expression of IgG1 antibody targeting NS3 helicase inhibits replication of highly efficient hepatitis C Virus 2a clone.

Chandra PK, Hazari S, Poat B, Gunduz F, Prabhu R, Liu G, Burioni R, Clementi M, Garry RF, Dash S.

Virol J. 2010 Jun 7;7:118. doi: 10.1186/1743-422X-7-118.


Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathway.

Hazari S, Chandra PK, Poat B, Datta S, Garry RF, Foster TP, Kousoulas G, Wakita T, Dash S.

Virol J. 2010 Feb 11;7:36. doi: 10.1186/1743-422X-7-36.


Subgenotypes of hepatitis B virus genotype D (D1, D2, D3 and D5) in India: differential pattern of mutations, liver injury and occult HBV infection.

Chandra PK, Biswas A, Datta S, Banerjee A, Panigrahi R, Chakrabarti S, De BK, Chakravarty R.

J Viral Hepat. 2009 Oct;16(10):749-56. doi: 10.1111/j.1365-2893.2009.01129.x. Epub 2009 May 3.


Application of COLD-PCR for improved detection of KRAS mutations in clinical samples.

Zuo Z, Chen SS, Chandra PK, Galbincea JM, Soape M, Doan S, Barkoh BA, Koeppen H, Medeiros LJ, Luthra R.

Mod Pathol. 2009 Aug;22(8):1023-31. doi: 10.1038/modpathol.2009.59. Epub 2009 May 8.


Genetic characterization of hepatitis B virus in peripheral blood leukocytes: evidence for selection and compartmentalization of viral variants with the immune escape G145R mutation.

Datta S, Panigrahi R, Biswas A, Chandra PK, Banerjee A, Mahapatra PK, Panda CK, Chakrabarti S, Bhattacharya SK, Biswas K, Chakravarty R.

J Virol. 2009 Oct;83(19):9983-92. doi: 10.1128/JVI.01905-08. Epub 2009 May 6.


Molecular epidemiology and clinical significance of hepatitis B virus genotypes, core promoter and precore mutations in eastern India.

Datta S, Biswas A, Chandra PK, Banerjee A, Panigrahi R, Mahapatra PK, Chakrabarti S, Panda CK, Chakravarty R.

Intervirology. 2008;51(4):275-84. doi: 10.1159/000170902. Epub 2008 Nov 6.


Analysis of hepatitis B virus X gene phylogeny, genetic variability and its impact on pathogenesis: implications in Eastern Indian HBV carriers.

Datta S, Banerjee A, Chandra PK, Biswas A, Panigrahi R, Mahapatra PK, Panda CK, Chakrabarti S, Bhattacharya SK, Chakravarty R.

Virology. 2008 Dec 20;382(2):190-8. doi: 10.1016/j.virol.2008.09.007. Epub 2008 Oct 25.


Efficacy of high-dose Lactobacillus rhamnosus GG in controlling acute watery diarrhea in Indian children: a randomized controlled trial.

Basu S, Paul DK, Ganguly S, Chatterjee M, Chandra PK.

J Clin Gastroenterol. 2009 Mar;43(3):208-13. doi: 10.1097/MCG.0b013e31815a5780.


Fetal ascites owing to congenital cytomegalovirus: response to ganciclovir.

Basu S, Chandra PK, Basu S.

Ann Trop Paediatr. 2008 Sep;28(3):235-9. doi: 10.1179/146532808X335705.


Frequency and distribution of hepatitis B virus genotypes among eastern Indian voluntary blood donors: Association with precore and basal core promoter mutations.

Biswas A, Chandra PK, Datta S, Panigrahi R, Banerjee A, Chakrabarti S, Biswas K, Patra D, Bhattacharya P, Biswas K, Chakravarty R.

Hepatol Res. 2009 Jan;39(1):53-9. doi: 10.1111/j.1872-034X.2008.00403.x. Epub 2008 Aug 18.


Antibiotic misuse in children by the primary care physicians--an Indian experience.

Basu S, Chatterjee M, Chandra PK, Basu S.

Niger J Clin Pract. 2008 Mar;11(1):52-7.


Frequency and significance of hepatitis B virus surface gene variant circulating among 'antiHBc only' individuals in Eastern India.

Banerjee A, Chandra PK, Datta S, Biswas A, Bhattacharya P, Chakraborty S, Chakrabarti S, Bhattacharya SK, Chakravarty R.

J Clin Virol. 2007 Dec;40(4):312-7. Epub 2007 Nov 7.


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