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Items: 15


Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling.

Liu Z, Osipovitch M, Benraiss A, Huynh NPT, Foti R, Bates J, Chandler-Militello D, Findling RL, Tesar PJ, Nedergaard M, Windrem MS, Goldman SA.

Cell Rep. 2019 Jun 25;27(13):3832-3843.e6. doi: 10.1016/j.celrep.2019.05.088.


Human ESC-Derived Chimeric Mouse Models of Huntington's Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation.

Osipovitch M, Asenjo Martinez A, Mariani JN, Cornwell A, Dhaliwal S, Zou L, Chandler-Militello D, Wang S, Li X, Benraiss SJ, Agate R, Lampp A, Benraiss A, Windrem MS, Goldman SA.

Cell Stem Cell. 2019 Jan 3;24(1):107-122.e7. doi: 10.1016/j.stem.2018.11.010. Epub 2018 Dec 13.


Fluorescent Ca2+ indicators directly inhibit the Na,K-ATPase and disrupt cellular functions.

Smith NA, Kress BT, Lu Y, Chandler-Militello D, Benraiss A, Nedergaard M.

Sci Signal. 2018 Jan 30;11(515). pii: eaal2039. doi: 10.1126/scisignal.aal2039.


Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia.

Windrem MS, Osipovitch M, Liu Z, Bates J, Chandler-Militello D, Zou L, Munir J, Schanz S, McCoy K, Miller RH, Wang S, Nedergaard M, Findling RL, Tesar PJ, Goldman SA.

Cell Stem Cell. 2017 Aug 3;21(2):195-208.e6. doi: 10.1016/j.stem.2017.06.012. Epub 2017 Jul 20.


Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

Benraiss A, Wang S, Herrlinger S, Li X, Chandler-Militello D, Mauceri J, Burm HB, Toner M, Osipovitch M, Jim Xu Q, Ding F, Wang F, Kang N, Kang J, Curtin PC, Brunner D, Windrem MS, Munoz-Sanjuan I, Nedergaard M, Goldman SA.

Nat Commun. 2016 Jun 7;7:11758. doi: 10.1038/ncomms11758.


A competitive advantage by neonatally engrafted human glial progenitors yields mice whose brains are chimeric for human glia.

Windrem MS, Schanz SJ, Morrow C, Munir J, Chandler-Militello D, Wang S, Goldman SA.

J Neurosci. 2014 Nov 26;34(48):16153-61. doi: 10.1523/JNEUROSCI.1510-14.2014.


Human glial chimeric mice reveal astrocytic dependence of JC virus infection.

Kondo Y, Windrem MS, Zou L, Chandler-Militello D, Schanz SJ, Auvergne RM, Betstadt SJ, Harrington AR, Johnson M, Kazarov A, Gorelik L, Goldman SA.

J Clin Invest. 2014 Dec;124(12):5323-36. doi: 10.1172/JCI76629. Epub 2014 Nov 17.


Transcriptional differences between normal and glioma-derived glial progenitor cells identify a core set of dysregulated genes.

Auvergne RM, Sim FJ, Wang S, Chandler-Militello D, Burch J, Al Fanek Y, Davis D, Benraiss A, Walter K, Achanta P, Johnson M, Quinones-Hinojosa A, Natesan S, Ford HL, Goldman SA.

Cell Rep. 2013 Jun 27;3(6):2127-41. doi: 10.1016/j.celrep.2013.04.035. Epub 2013 May 30. Erratum in: Cell Rep. 2013 Jul 25;4(2):402.


Purine receptor mediated actin cytoskeleton remodeling of human fibroblasts.

Goldman N, Chandler-Militello D, Langevin HM, Nedergaard M, Takano T.

Cell Calcium. 2013 Apr;53(4):297-301. doi: 10.1016/j.ceca.2013.01.004. Epub 2013 Feb 22.


Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination.

Wang S, Bates J, Li X, Schanz S, Chandler-Militello D, Levine C, Maherali N, Studer L, Hochedlinger K, Windrem M, Goldman SA.

Cell Stem Cell. 2013 Feb 7;12(2):252-64. doi: 10.1016/j.stem.2012.12.002.


Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2.

Eyler CE, Wu Q, Yan K, MacSwords JM, Chandler-Militello D, Misuraca KL, Lathia JD, Forrester MT, Lee J, Stamler JS, Goldman SA, Bredel M, McLendon RE, Sloan AE, Hjelmeland AB, Rich JN.

Cell. 2011 Jul 8;146(1):53-66. doi: 10.1016/j.cell.2011.06.006.


Prospective identification, isolation, and profiling of a telomerase-expressing subpopulation of human neural stem cells, using sox2 enhancer-directed fluorescence-activated cell sorting.

Wang S, Chandler-Militello D, Lu G, Roy NS, Zielke A, Auvergne R, Stanwood N, Geschwind D, Coppola G, Nicolis SK, Sim FJ, Goldman SA.

J Neurosci. 2010 Nov 3;30(44):14635-48. doi: 10.1523/JNEUROSCI.1729-10.2010.


Retrovirally mediated telomerase immortalization of neural progenitor cells.

Roy NS, Chandler-Militello D, Lu G, Wang S, Goldman SA.

Nat Protoc. 2007;2(11):2815-25.


Surveillance mechanism linking Bub1 loss to the p53 pathway.

Gjoerup OV, Wu J, Chandler-Militello D, Williams GL, Zhao J, Schaffhausen B, Jat PS, Roberts TM.

Proc Natl Acad Sci U S A. 2007 May 15;104(20):8334-9. Epub 2007 May 8.


Rad23 and Rpn10 serve as alternative ubiquitin receptors for the proteasome.

Elsasser S, Chandler-Militello D, Müller B, Hanna J, Finley D.

J Biol Chem. 2004 Jun 25;279(26):26817-22. Epub 2004 Apr 26.

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