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Items: 20


Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids.

Huang Q, Chan KY, Tobey IG, Chan YA, Poterba T, Boutros CL, Balazs AB, Daneman R, Bloom JM, Seed C, Deverman BE.

PLoS One. 2019 Nov 14;14(11):e0225206. doi: 10.1371/journal.pone.0225206. eCollection 2019.


MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription-replication conflicts.

Chang EY, Tsai S, Aristizabal MJ, Wells JP, Coulombe Y, Busatto FF, Chan YA, Kumar A, Dan Zhu Y, Wang AY, Fournier LA, Hieter P, Kobor MS, Masson JY, Stirling PC.

Nat Commun. 2019 Sep 19;10(1):4265. doi: 10.1038/s41467-019-12271-w.


Large-scale recoding of a bacterial genome by iterative recombineering of synthetic DNA.

Lau YH, Stirling F, Kuo J, Karrenbelt MAP, Chan YA, Riesselman A, Horton CA, Schäfer E, Lips D, Weinstock MT, Gibson DG, Way JC, Silver PA.

Nucleic Acids Res. 2017 Jun 20;45(11):6971-6980. doi: 10.1093/nar/gkx415.


Efficient size-independent chromosome delivery from yeast to cultured cell lines.

Brown DM, Chan YA, Desai PJ, Grzesik P, Oldfield LM, Vashee S, Way JC, Silver PA, Glass JI.

Nucleic Acids Res. 2017 Apr 20;45(7):e50. doi: 10.1093/nar/gkw1252.


Lytic transglycosylases LtgA and LtgD perform distinct roles in remodeling, recycling and releasing peptidoglycan in Neisseria gonorrhoeae.

Schaub RE, Chan YA, Lee M, Hesek D, Mobashery S, Dillard JP.

Mol Microbiol. 2016 Dec;102(5):865-881. doi: 10.1111/mmi.13496. Epub 2016 Sep 26.


Mechanisms of genome instability induced by RNA-processing defects.

Chan YA, Hieter P, Stirling PC.

Trends Genet. 2014 Jun;30(6):245-53. doi: 10.1016/j.tig.2014.03.005. Epub 2014 May 1. Review.


Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chip.

Chan YA, Aristizabal MJ, Lu PY, Luo Z, Hamza A, Kobor MS, Stirling PC, Hieter P.

PLoS Genet. 2014 Apr 17;10(4):e1004288. doi: 10.1371/journal.pgen.1004288. eCollection 2014 Apr.


From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II.

Braberg H, Jin H, Moehle EA, Chan YA, Wang S, Shales M, Benschop JJ, Morris JH, Qiu C, Hu F, Tang LK, Fraser JS, Holstege FC, Hieter P, Guthrie C, Kaplan CD, Krogan NJ.

Cell. 2013 Aug 15;154(4):775-88. doi: 10.1016/j.cell.2013.07.033. Epub 2013 Aug 8.


Mating pair formation homologue TraG is a variable membrane protein essential for contact-independent type IV secretion of chromosomal DNA by Neisseria gonorrhoeae.

Kohler PL, Chan YA, Hackett KT, Turner N, Hamilton HL, Cloud-Hansen KA, Dillard JP.

J Bacteriol. 2013 Apr;195(8):1666-79. doi: 10.1128/JB.02098-12. Epub 2013 Feb 1.


The lytic transglycosylases of Neisseria gonorrhoeae.

Chan YA, Hackett KT, Dillard JP.

Microb Drug Resist. 2012 Jun;18(3):271-9. doi: 10.1089/mdr.2012.0001. Epub 2012 Mar 20. Review.


Neisseria gonorrhoeae virulence factor NG1686 is a bifunctional M23B family metallopeptidase that influences resistance to hydrogen peroxide and colony morphology.

Stohl EA, Chan YA, Hackett KT, Kohler PL, Dillard JP, Seifert HS.

J Biol Chem. 2012 Mar 30;287(14):11222-33. doi: 10.1074/jbc.M111.338830. Epub 2012 Feb 13.


R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants.

Stirling PC, Chan YA, Minaker SW, Aristizabal MJ, Barrett I, Sipahimalani P, Kobor MS, Hieter P.

Genes Dev. 2012 Jan 15;26(2):163-75. doi: 10.1101/gad.179721.111.


Quantitative mass spectrometry catalogues Salmonella pathogenicity island-2 effectors and identifies their cognate host binding partners.

Auweter SD, Bhavsar AP, de Hoog CL, Li Y, Chan YA, van der Heijden J, Lowden MJ, Coombes BK, Rogers LD, Stoynov N, Foster LJ, Finlay BB.

J Biol Chem. 2011 Jul 8;286(27):24023-35. doi: 10.1074/jbc.M111.224600. Epub 2011 May 12.


Adsorption mechanism of selenate and selenite on the binary oxide systems.

Chan YT, Kuan WH, Chen TY, Wang MK.

Water Res. 2009 Sep;43(17):4412-20. doi: 10.1016/j.watres.2009.06.056. Epub 2009 Jul 4.


Biosynthesis of polyketide synthase extender units.

Chan YA, Podevels AM, Kevany BM, Thomas MG.

Nat Prod Rep. 2009 Jan;26(1):90-114. Review.


Formation and characterization of acyl carrier protein-linked polyketide synthase extender units.

Chan YA, Thomas MG.

Methods Enzymol. 2009;459:143-63. doi: 10.1016/S0076-6879(09)04607-2.


Nonribosomal peptide synthetases involved in the production of medically relevant natural products.

Felnagle EA, Jackson EE, Chan YA, Podevels AM, Berti AD, McMahon MD, Thomas MG.

Mol Pharm. 2008 Mar-Apr;5(2):191-211. doi: 10.1021/mp700137g. Epub 2008 Jan 25. Review.


Hydroxymalonyl-acyl carrier protein (ACP) and aminomalonyl-ACP are two additional type I polyketide synthase extender units.

Chan YA, Boyne MT 2nd, Podevels AM, Klimowicz AK, Handelsman J, Kelleher NL, Thomas MG.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14349-54. Epub 2006 Sep 18.


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