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Nanoparticle Uptake in a Spontaneous and Immunocompetent Woodchuck Liver Cancer Model.

Liu LY, Ma XZ, Ouyang B, Ings DP, Marwah S, Liu J, Chen AY, Gupta R, Manuel J, Chen XC, Gage BK, Cirlan I, Khuu N, Chung S, Camat D, Cheng M, Sekhon M, Zagorovsky K, Abdou Mohamed MA, Thoeni C, Atif J, Echeverri J, Kollmann D, Fischer S, Bader GD, Chan WCW, Michalak TI, McGilvray ID, MacParland SA.

ACS Nano. 2020 Apr 7. doi: 10.1021/acsnano.0c00468. [Epub ahead of print]


Peripheral T cell lymphomas: from the bench to the clinic.

Fiore D, Cappelli LV, Broccoli A, Zinzani PL, Chan WC, Inghirami G.

Nat Rev Cancer. 2020 Apr 6. doi: 10.1038/s41568-020-0247-0. [Epub ahead of print] Review.


Nano Research for COVID-19.

Chan WCW.

ACS Nano. 2020 Mar 31. doi: 10.1021/acsnano.0c02540. [Epub ahead of print] No abstract available.


Diagnosing COVID-19: The Disease and Tools for Detection.

Udugama B, Kadhiresan P, Kozlowski HN, Malekjahani A, Osborne M, Li VYC, Chen H, Mubareka S, Gubbay J, Chan WCW.

ACS Nano. 2020 Mar 30. doi: 10.1021/acsnano.0c02624. [Epub ahead of print]


Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism.

Schauer NJ, Liu X, Magin RS, Doherty LM, Chan WC, Ficarro SB, Hu W, Roberts RM, Iacob RE, Stolte B, Giacomelli AO, Perera S, McKay K, Boswell SA, Weisberg EL, Ray A, Chauhan D, Dhe-Paganon S, Anderson KC, Griffin JD, Li J, Hahn WC, Sorger PK, Engen JR, Stegmaier K, Marto JA, Buhrlage SJ.

Sci Rep. 2020 Mar 24;10(1):5324. doi: 10.1038/s41598-020-62076-x.


OX40+ plasmacytoid dendritic cells in the tumor microenvironment promote antitumor immunity.

Poropatich KO, Dominguez D, Chan WC, Andrade J, Zha Y, Wray BD, Miska J, Qin L, Cole LE, Coates S, Patel UA, Samant S, Zhang B.

J Clin Invest. 2020 Mar 17. pii: 131992. doi: 10.1172/JCI131992. [Epub ahead of print]


Diurnal Cortisol Slope Mediates the Association Between Affect and Memory Retrieval in Older Adults With Mild Cognitive Impairment: A Path-Analytical Study.

Ho RTH, Fong TCT, Yau JCY, Chan WC, Kwan JSK, Chiu PKC, Lam LCW.

Front Aging Neurosci. 2020 Feb 21;12:35. doi: 10.3389/fnagi.2020.00035. eCollection 2020.


The novel lncRNA BlackMamba controls the neoplastic phenotype of ALK- anaplastic large cell lymphoma by regulating the DNA helicase HELLS.

Fragliasso V, Verma A, Manzotti G, Tameni A, Bareja R, Heavican TB, Iqbal J, Wang R, Fiore D, Mularoni V, Chan WC, Lhoumaud P, Skok J, Zanetti E, Merli F, Ciarrocchi A, Elemento O, Inghirami G.

Leukemia. 2020 Mar 2. doi: 10.1038/s41375-020-0754-8. [Epub ahead of print]


Tunable and precise miniature lithium heater for point-of-care applications.

Udugama B, Kadhiresan P, Chan WCW.

Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):4632-4641. doi: 10.1073/pnas.1916562117. Epub 2020 Feb 18.


Genomic characterization of diffuse large B-cell lymphoma transformation of nodular lymphocyte-predominant Hodgkin lymphoma.

Song JY, Egan C, Bouska AC, Zhang W, Gong Q, Venkataraman G, Herrera AF, Chen L, Ottesen R, Niland JC, Bedell V, Valle-Catuna M, Murata-Collins J, Weisenburger DD, Iqbal J, Jaffe ES, Chan WC.

Leukemia. 2020 Feb 13. doi: 10.1038/s41375-020-0739-7. [Epub ahead of print] No abstract available.


Higher dementia incidence in older adults with poor visual acuity.

Lee ATC, Richards M, Chan WC, Chiu HFK, Lee RSY, Lam LCW.

J Gerontol A Biol Sci Med Sci. 2020 Feb 11. pii: glaa036. doi: 10.1093/gerona/glaa036. [Epub ahead of print]


The entry of nanoparticles into solid tumours.

Sindhwani S, Syed AM, Ngai J, Kingston BR, Maiorino L, Rothschild J, MacMillan P, Zhang Y, Rajesh NU, Hoang T, Wu JLY, Wilhelm S, Zilman A, Gadde S, Sulaiman A, Ouyang B, Lin Z, Wang L, Egeblad M, Chan WCW.

Nat Mater. 2020 Jan 13. doi: 10.1038/s41563-019-0566-2. [Epub ahead of print]


Differences in Major Bleeding Events Between Patients With Severe Hemophilia A and Hemophilia B: A Nationwide, Population-Based Cohort Study.

Shih MY, Wang JD, Yin JD, Tsan YT, Chan WC.

Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619888023. doi: 10.1177/1076029619888023.


Liposome Imaging in Optically Cleared Tissues.

Syed AM, MacMillan P, Ngai J, Wilhelm S, Sindhwani S, Kingston BR, Wu JLY, Llano-Suárez P, Lin ZP, Ouyang B, Kahiel Z, Gadde S, Chan WCW.

Nano Lett. 2020 Feb 12;20(2):1362-1369. doi: 10.1021/acs.nanolett.9b04853. Epub 2020 Jan 22.


Endothelialized collagen based pseudo-islets enables tuneable subcutaneous diabetes therapy.

Vlahos AE, Kinney SM, Kingston BR, Keshavjee S, Won SY, Martyts A, Chan WCW, Sefton MV.

Biomaterials. 2020 Feb;232:119710. doi: 10.1016/j.biomaterials.2019.119710. Epub 2019 Dec 26.


Immune gene expression profiling reveals heterogeneity in luminal breast tumors.

Zhu B, Tse LA, Wang D, Koka H, Zhang T, Abubakar M, Lee P, Wang F, Wu C, Tsang KH, Chan WC, Law SH, Li M, Li W, Wu S, Liu Z, Huang B, Zhang H, Tang E, Kan Z, Lee S, Park YH, Nam SJ, Wang M, Sun X, Jones K, Zhu B, Hutchinson A, Hicks B, Prokunina-Olsson L, Shi J, Garcia-Closas M, Chanock S, Yang XR.

Breast Cancer Res. 2019 Dec 19;21(1):147. doi: 10.1186/s13058-019-1218-9.


Inhibition of MDR1 Overcomes Resistance to Brentuximab Vedotin in Hodgkin Lymphoma.

Chen R, Herrera AF, Hou J, Chen L, Wu J, Guo Y, Synold TW, Ngo VN, Puverel S, Mei M, Popplewell L, Yi S, Song JY, Tao S, Wu X, Chan WC, Forman SJ, Kwak LW, Rosen ST, Newman EM.

Clin Cancer Res. 2020 Mar 1;26(5):1034-1044. doi: 10.1158/1078-0432.CCR-19-1768. Epub 2019 Dec 6.


Myeloproliferative and lymphoproliferative malignancies occurring in the same patient: a nationwide discovery cohort.

Holst JM, Plesner TL, Pedersen MB, Frederiksen H, Møller MB, Clausen MR, Hansen MC, Hamilton-Dutoit SJ, Nørgaard P, Johansen P, Eberlein TR, Mortensen BK, Mathiasen G, Øvlisen A, Wang R, Wang C, Zhang W, Ommen HB, Stentoft J, Ludvigsen M, Tam W, Chan WC, Inghirami G, d'Amore F.

Haematologica. 2019 Nov 28. pii: haematol.2019.225839. doi: 10.3324/haematol.2019.225839. [Epub ahead of print]


Expansion of PD1-positive T Cells in Nodal Marginal Zone Lymphoma: A Potential Diagnostic Pitfall.

Egan C, Laurent C, Alejo JC, Pileri S, Campo E, Swerdlow SH, Piris M, Chan WC, Warnke R, Gascoyne RD, Xi L, Raffeld M, Pittaluga S, Jaffe ES.

Am J Surg Pathol. 2019 Nov 22. doi: 10.1097/PAS.0000000000001414. [Epub ahead of print]


Chemical activation of divergent protein tyrosine phosphatase domains with cyanine-based biarsenicals.

Plaman BA, Chan WC, Bishop AC.

Sci Rep. 2019 Nov 6;9(1):16148. doi: 10.1038/s41598-019-52002-1.


Circulating plasma exosomes in obstructive sleep apnoea and reverse dipping blood pressure.

Khalyfa A, Gozal D, Chan WC, Andrade J, Prasad B.

Eur Respir J. 2020 Jan 30;55(1). pii: 1901072. doi: 10.1183/13993003.01072-2019. Print 2020 Jan.


High-definition transcranial direct current stimulation-An open-label pilot intervention in alleviating depressive symptoms and cognitive deficits in late-life depression.

Wong HL, Chan WC, Wong YL, Wong SN, Yung HY, Wong SC, Cheng PC.

CNS Neurosci Ther. 2019 Nov;25(11):1244-1253. doi: 10.1111/cns.13253. Epub 2019 Oct 28.


Pathways to care for people with dementia: An international multicentre study.

Volpe U, Amin H, Ayinde OO, Burns A, Chan WC, David R, Dejanovic SD, Djokic G, Eraslan D, Fischer GAL, Gracia-García P, Hamdani SU, Han C, Jafri H, Kallivayalil RA, Kriekaart RL, Kua EH, Lam LCW, Lecic-Tosevski D, Leroi I, Lobo A, Mihai A, Minhas FA, Mistry H, Ogundele AT, Olde Rikkert MGM, Olivera J, Palumbo C, Parker A, Pejuskovic B, Riese F, Robert P, Semrau M, Stoppe G, Sudhakar S, Tirintica AR, Tofique S, Tsoi C, Wolski L, Yalug I, Wang H, Yu X, Sartorius N.

Int J Geriatr Psychiatry. 2020 Feb;35(2):163-173. doi: 10.1002/gps.5223. Epub 2019 Dec 1.


Moderating effects of meaning in life on the relationship between depression and self-competence in death work among helping professionals.

Chan WCH, Tin AF, Wong ALY.

Death Stud. 2019 Oct 7:1-9. doi: 10.1080/07481187.2019.1671541. [Epub ahead of print]


Higher dementia incidence in older adults with type 2 diabetes and large reduction in HbA1c.

Lee ATC, Richards M, Chan WC, Chiu HFK, Lee RSY, Lam LCW.

Age Ageing. 2019 Nov 1;48(6):838-844. doi: 10.1093/ageing/afz108.


Understanding family involvement in body donation in Hong Kong: A qualitative study of registered donors and bereaved family members.

Chan WCH, Chan SO, Wong ALY, Ng PKL.

Health Soc Care Community. 2020 Jan;28(1):270-278. doi: 10.1111/hsc.12861. Epub 2019 Sep 30.


Reproducing the molecular subclassification of peripheral T-cell lymphoma-NOS by immunohistochemistry.

Amador C, Greiner TC, Heavican TB, Smith LM, Galvis KT, Lone W, Bouska A, D'Amore F, Pedersen MB, Pileri S, Agostinelli C, Feldman AL, Rosenwald A, Ott G, Mottok A, Savage KJ, de Leval L, Gaulard P, Lim ST, Ong CK, Ondrejka SL, Song J, Campo E, Jaffe ES, Staudt LM, Rimsza LM, Vose J, Weisenburger DD, Chan WC, Iqbal J.

Blood. 2019 Dec 12;134(24):2159-2170. doi: 10.1182/blood.2019000779.


Randomized controlled trial of TDCS on cognition in 201 seniors with mild neurocognitive disorder.

Lu H, Chan SSM, Chan WC, Lin C, Cheng CPW, Linda Chiu Wa L.

Ann Clin Transl Neurol. 2019 Oct;6(10):1938-1948. doi: 10.1002/acn3.50823. Epub 2019 Sep 17.


Lgr5 and Col22a1 Mark Progenitor Cells in the Lineage toward Juvenile Articular Chondrocytes.

Feng C, Chan WCW, Lam Y, Wang X, Chen P, Niu B, Ng VCW, Yeo JC, Stricker S, Cheah KSE, Koch M, Mundlos S, Ng HH, Chan D.

Stem Cell Reports. 2019 Oct 8;13(4):713-729. doi: 10.1016/j.stemcr.2019.08.006. Epub 2019 Sep 12.


Nanoparticle Size Influences Antigen Retention and Presentation in Lymph Node Follicles for Humoral Immunity.

Zhang YN, Lazarovits J, Poon W, Ouyang B, Nguyen LNM, Kingston BR, Chan WCW.

Nano Lett. 2019 Oct 9;19(10):7226-7235. doi: 10.1021/acs.nanolett.9b02834. Epub 2019 Sep 17.


Associations between Coffee Products and Breast Cancer Risk: a Case-Control study in Hong Kong Chinese Women.

Lee PMY, Chan WC, Kwok CC, Wu C, Law SH, Tsang KH, Yu WC, Yeung YC, Chang LDJ, Wong CKM, Wang F, Tse LA.

Sci Rep. 2019 Sep 3;9(1):12684. doi: 10.1038/s41598-019-49205-x.


Engineering Steps for Mobile Point-of-Care Diagnostic Devices.

Malekjahani A, Sindhwani S, Syed AM, Chan WCW.

Acc Chem Res. 2019 Sep 17;52(9):2406-2414. doi: 10.1021/acs.accounts.9b00200. Epub 2019 Aug 20.


Screening Of Pulmonary Hypertension in Methamphetamine Abusers (SOPHMA): rationale and design of a multicentre, cross-sectional study.

Cheng Y, Tung CK, Chung AKK, Liu WW, Huang D, Chan PH, Lam M, Chan WC, Siu CW, Hai JJ.

BMJ Open. 2019 Aug 1;9(8):e027193. doi: 10.1136/bmjopen-2018-027193.


Timing Is Everything: Impact of Naturally Occurring Staphylococcus aureus AgrC Cytoplasmic Domain Adaptive Mutations on Autoinduction.

Sloan TJ, Murray E, Yokoyama M, Massey RC, Chan WC, Bonev BB, Williams P.

J Bacteriol. 2019 Sep 20;201(20). pii: e00409-19. doi: 10.1128/JB.00409-19. Print 2019 Oct 15.


Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study.

Lipnicki DM, Makkar SR, Crawford JD, Thalamuthu A, Kochan NA, Lima-Costa MF, Castro-Costa E, Ferri CP, Brayne C, Stephan B, Llibre-Rodriguez JJ, Llibre-Guerra JJ, Valhuerdi-Cepero AJ, Lipton RB, Katz MJ, Derby CA, Ritchie K, Ancelin ML, Carrière I, Scarmeas N, Yannakoulia M, Hadjigeorgiou GM, Lam L, Chan WC, Fung A, Guaita A, Vaccaro R, Davin A, Kim KW, Han JW, Suh SW, Riedel-Heller SG, Roehr S, Pabst A, van Boxtel M, Köhler S, Deckers K, Ganguli M, Jacobsen EP, Hughes TF, Anstey KJ, Cherbuin N, Haan MN, Aiello AE, Dang K, Kumagai S, Chen T, Narazaki K, Ng TP, Gao Q, Nyunt MSZ, Scazufca M, Brodaty H, Numbers K, Trollor JN, Meguro K, Yamaguchi S, Ishii H, Lobo A, Lopez-Anton R, Santabárbara J, Leung Y, Lo JW, Popovic G, Sachdev PS; for Cohort Studies of Memory in an International Consortium (COSMIC).

PLoS Med. 2019 Jul 23;16(7):e1002853. doi: 10.1371/journal.pmed.1002853. eCollection 2019 Jul.


Antitumor Activity of 1,18-Octadecanedioic Acid-Paclitaxel Complexed with Human Serum Albumin.

Callmann CE, LeGuyader CLM, Burton ST, Thompson MP, Hennis R, Barback C, Henriksen NM, Chan WC, Jaremko MJ, Yang J, Garcia A, Burkart MD, Gilson MK, Momper JD, Bertin PA, Gianneschi NC.

J Am Chem Soc. 2019 Jul 31;141(30):11765-11769. doi: 10.1021/jacs.9b04272. Epub 2019 Jul 18.


Assessing micrometastases as a target for nanoparticles using 3D microscopy and machine learning.

Kingston BR, Syed AM, Ngai J, Sindhwani S, Chan WCW.

Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):14937-14946. doi: 10.1073/pnas.1907646116. Epub 2019 Jul 8.


Supervised Learning and Mass Spectrometry Predicts the in Vivo Fate of Nanomaterials.

Lazarovits J, Sindhwani S, Tavares AJ, Zhang Y, Song F, Audet J, Krieger JR, Syed AM, Stordy B, Chan WCW.

ACS Nano. 2019 Jul 23;13(7):8023-8034. doi: 10.1021/acsnano.9b02774. Epub 2019 Jul 3.


Redefining the Experimental and Methods Sections.

Millstone JE, Chan WCW, Kagan CR, Liz-Marzán LM, Kotov NA, Mulvaney PA, Parak WJ, Rogach AL, Weiss PS, Schaak RE.

ACS Nano. 2019 May 28;13(5):4862-4864. doi: 10.1021/acsnano.9b03753. No abstract available.


Long-Term Outcomes of the Benefit-Finding Group Intervention for Alzheimer Family Caregivers: A Cluster-Randomized Double-Blind Controlled Trial.

Cheng ST, Chan WC, Lam LCW.

Am J Geriatr Psychiatry. 2019 Sep;27(9):984-994. doi: 10.1016/j.jagp.2019.03.013. Epub 2019 Mar 26.


Effect of CYP2D6 and CYP3A4 Genotypes on the Efficacy of Cholinesterase Inhibitors in Southern Chinese Patients With Alzheimer's Disease.

Ma SL, Tang NLS, Wat KHY, Tang JHY, Lau KH, Law CB, Chiu J, Tam CCW, Poon TK, Lin KL, Kng CPL, Kong HL, Chan TY, Chan WC, Lam LCW.

Am J Alzheimers Dis Other Demen. 2019 Aug;34(5):302-307. doi: 10.1177/1533317519848237. Epub 2019 May 7.


Characterizing the protein corona of sub-10 nm nanoparticles.

Glancy D, Zhang Y, Wu JLY, Ouyang B, Ohta S, Chan WCW.

J Control Release. 2019 Jun 28;304:102-110. doi: 10.1016/j.jconrel.2019.04.023. Epub 2019 Apr 17.


Global Brain Transcriptome Analysis of a Tpp1 Neuronal Ceroid Lipofuscinoses Mouse Model.

Domowicz MS, Chan WC, Claudio-Vázquez P, Henry JG, Ware CB, Andrade J, Dawson G, Schwartz NB.

ASN Neuro. 2019 Jan-Dec;11:1759091419843393. doi: 10.1177/1759091419843393.


Elimination Pathways of Nanoparticles.

Poon W, Zhang YN, Ouyang B, Kingston BR, Wu JLY, Wilhelm S, Chan WCW.

ACS Nano. 2019 May 28;13(5):5785-5798. doi: 10.1021/acsnano.9b01383. Epub 2019 Apr 26.


Ophthalmologic manifestations in Taiwanese patients with mucopolysaccharidoses.

Lin HY, Chan WC, Chen LJ, Lee YC, Yeh SI, Niu DM, Chiu PC, Tsai WH, Hwu WL, Chuang CK, Lin SP.

Mol Genet Genomic Med. 2019 May;7(5):e00617. doi: 10.1002/mgg3.617. Epub 2019 Mar 8.


Cytologic diagnosis of metastatic malignant phyllodes tumor of the breast in pleural effusion.

Li JJX, Chan WC, Chau HHL, Wu C, Tse GM.

Diagn Cytopathol. 2019 Jun;47(6):599-602. doi: 10.1002/dc.24151. Epub 2019 Mar 4.


Integration of transcriptional and mutational data simplifies the stratification of peripheral T-cell lymphoma.

Maura F, Agnelli L, Leongamornlert D, Bolli N, Chan WC, Dodero A, Carniti C, Heavican TB, Pellegrinelli A, Pruneri G, Butler A, Bhosle SG, Chiappella A, Di Rocco A, Zinzani PL, Zaja F, Piva R, Inghirami G, Wang W, Palomero T, Iqbal J, Neri A, Campbell PJ, Corradini P.

Am J Hematol. 2019 Jun;94(6):628-634. doi: 10.1002/ajh.25450. Epub 2019 Mar 19.


L-Type Cav 1.2 Calcium Channel-α-1C Regulates Response to Rituximab in Diffuse Large B-Cell Lymphoma.

Zhang JY, Zhang PP, Zhou WP, Yu JY, Yao ZH, Chu JF, Yao SN, Wang C, Lone W, Xia QX, Ma J, Yang SJ, Liu KD, Dong ZG, Guo YJ, Smith LM, McKeithan TW, Chan WC, Iqbal J, Liu YY.

Clin Cancer Res. 2019 Jul 1;25(13):4168-4178. doi: 10.1158/1078-0432.CCR-18-2146. Epub 2019 Mar 1.


Extended dual antiplatelet therapy for Asian patients with acute coronary syndrome: expert recommendations.

Chen WWC, Law KK, Li SK, Chan WCK, Cheong A, Fong PC, Hung YT, Lai SWK, Leung GTC, Wong EML, Wong RWK, Yan CT, Yan VWT, Au Yeong TCK.

Intern Med J. 2019 Mar;49 Suppl 1:5-8. doi: 10.1111/imj.14153. Review.


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