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Antitumor Activity of 1,18-Octadecanedioic Acid-Paclitaxel Complexed with Human Serum Albumin.

Callmann CE, LeGuyader CLM, Burton ST, Thompson MP, Hennis R, Barback C, Henriksen NM, Chan WC, Jaremko MJ, Yang J, Garcia A, Burkart MD, Gilson MK, Momper JD, Bertin PA, Gianneschi NC.

J Am Chem Soc. 2019 Jul 18. doi: 10.1021/jacs.9b04272. [Epub ahead of print]


Assessing micrometastases as a target for nanoparticles using 3D microscopy and machine learning.

Kingston BR, Syed AM, Ngai J, Sindhwani S, Chan WCW.

Proc Natl Acad Sci U S A. 2019 Jul 8. pii: 201907646. doi: 10.1073/pnas.1907646116. [Epub ahead of print]


Supervised Learning and Mass Spectrometry Predicts the in Vivo Fate of Nanomaterials.

Lazarovits J, Sindhwani S, Tavares AJ, Zhang Y, Song F, Audet J, Krieger JR, Syed AM, Stordy B, Chan WCW.

ACS Nano. 2019 Jul 3. doi: 10.1021/acsnano.9b02774. [Epub ahead of print]


Redefining the Experimental and Methods Sections.

Millstone JE, Chan WCW, Kagan CR, Liz-Marzán LM, Kotov NA, Mulvaney PA, Parak WJ, Rogach AL, Weiss PS, Schaak RE.

ACS Nano. 2019 May 28;13(5):4862-4864. doi: 10.1021/acsnano.9b03753. No abstract available.


Long-Term Outcomes of the Benefit-Finding Group Intervention for Alzheimer Family Caregivers: A Cluster-Randomized Double-Blind Controlled Trial.

Cheng ST, Chan WC, Lam LCW.

Am J Geriatr Psychiatry. 2019 Mar 26. pii: S1064-7481(19)30305-7. doi: 10.1016/j.jagp.2019.03.013. [Epub ahead of print]


Effect of CYP2D6 and CYP3A4 Genotypes on the Efficacy of Cholinesterase Inhibitors in Southern Chinese Patients With Alzheimer's Disease.

Ma SL, Tang NLS, Wat KHY, Tang JHY, Lau KH, Law CB, Chiu J, Tam CCW, Poon TK, Lin KL, Kng CPL, Kong HL, Chan TY, Chan WC, Lam LCW.

Am J Alzheimers Dis Other Demen. 2019 Aug;34(5):302-307. doi: 10.1177/1533317519848237. Epub 2019 May 7.


Characterizing the protein corona of sub-10 nm nanoparticles.

Glancy D, Zhang Y, Wu JLY, Ouyang B, Ohta S, Chan WCW.

J Control Release. 2019 Jun 28;304:102-110. doi: 10.1016/j.jconrel.2019.04.023. Epub 2019 Apr 17.


Global Brain Transcriptome Analysis of a Tpp1 Neuronal Ceroid Lipofuscinoses Mouse Model.

Domowicz MS, Chan WC, Claudio-Vázquez P, Henry JG, Ware CB, Andrade J, Dawson G, Schwartz NB.

ASN Neuro. 2019 Jan-Dec;11:1759091419843393. doi: 10.1177/1759091419843393.


Elimination Pathways of Nanoparticles.

Poon W, Zhang YN, Ouyang B, Kingston BR, Wu JLY, Wilhelm S, Chan WCW.

ACS Nano. 2019 May 28;13(5):5785-5798. doi: 10.1021/acsnano.9b01383. Epub 2019 Apr 26.


Ophthalmologic manifestations in Taiwanese patients with mucopolysaccharidoses.

Lin HY, Chan WC, Chen LJ, Lee YC, Yeh SI, Niu DM, Chiu PC, Tsai WH, Hwu WL, Chuang CK, Lin SP.

Mol Genet Genomic Med. 2019 May;7(5):e00617. doi: 10.1002/mgg3.617. Epub 2019 Mar 8.


Cytologic diagnosis of metastatic malignant phyllodes tumor of the breast in pleural effusion.

Li JJX, Chan WC, Chau HHL, Wu C, Tse GM.

Diagn Cytopathol. 2019 Jun;47(6):599-602. doi: 10.1002/dc.24151. Epub 2019 Mar 4.


Integration of transcriptional and mutational data simplifies the stratification of peripheral T-cell lymphoma.

Maura F, Agnelli L, Leongamornlert D, Bolli N, Chan WC, Dodero A, Carniti C, Heavican TB, Pellegrinelli A, Pruneri G, Butler A, Bhosle SG, Chiappella A, Di Rocco A, Zinzani PL, Zaja F, Piva R, Inghirami G, Wang W, Palomero T, Iqbal J, Neri A, Campbell PJ, Corradini P.

Am J Hematol. 2019 Jun;94(6):628-634. doi: 10.1002/ajh.25450. Epub 2019 Mar 19.


L-Type Cav 1.2 Calcium Channel-α-1C Regulates Response to Rituximab in Diffuse Large B-Cell Lymphoma.

Zhang JY, Zhang PP, Zhou WP, Yu JY, Yao ZH, Chu JF, Yao SN, Wang C, Lone W, Xia QX, Ma J, Yang SJ, Liu KD, Dong ZG, Guo YJ, Smith LM, McKeithan TW, Chan WC, Iqbal J, Liu YY.

Clin Cancer Res. 2019 Jul 1;25(13):4168-4178. doi: 10.1158/1078-0432.CCR-18-2146. Epub 2019 Mar 1.


Extended dual antiplatelet therapy for Asian patients with acute coronary syndrome: expert recommendations.

Chen WWC, Law KK, Li SK, Chan WCK, Cheong A, Fong PC, Hung YT, Lai SWK, Leung GTC, Wong EML, Wong RWK, Yan CT, Yan VWT, Au Yeong TCK.

Intern Med J. 2019 Mar;49 Suppl 1:5-8. doi: 10.1111/imj.14153.


Psychometric properties of Chinese version of Dementia Management Strategies Scale among family caregivers.

Chien WT, Chan SW, Gray R, Yip LK.

Hong Kong Med J. 2019 Feb;25 Suppl 3(1):40-47. No abstract available.


Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma.

Heavican TB, Bouska A, Yu J, Lone W, Amador C, Gong Q, Zhang W, Li Y, Dave BJ, Nairismägi ML, Greiner TC, Vose J, Weisenburger DD, Lachel C, Wang C, Fu K, Stevens JM, Lim ST, Ong CK, Gascoyne RD, Missiaglia E, Lemonnier F, Haioun C, Hartmann S, Pedersen MB, Laginestra MA, Wilcox RA, Teh BT, Yoshida N, Ohshima K, Seto M, Rosenwald A, Ott G, Campo E, Rimsza LM, Jaffe ES, Braziel RM, d'Amore F, Inghirami G, Bertoni F, de Leval L, Gaulard P, Staudt LM, McKeithan TW, Pileri S, Chan WC, Iqbal J.

Blood. 2019 Apr 11;133(15):1664-1676. doi: 10.1182/blood-2018-09-872549. Epub 2019 Feb 19.


The side population enriches for leukemia-propagating cell activity and Wnt pathway expression in zebrafish acute lymphoblastic leukemia.

Baeten JT, Waarts MR, Pruitt MM, Chan WC, Andrade J, de Jong JLO.

Haematologica. 2019 Jul;104(7):1388-1395. doi: 10.3324/haematol.2018.206417. Epub 2019 Jan 10.


Molecular and Genomic Landscape of Peripheral T-Cell Lymphoma.

Iqbal J, Amador C, McKeithan TW, Chan WC.

Cancer Treat Res. 2019;176:31-68. doi: 10.1007/978-3-319-99716-2_2.


Relationship between Cortical Thickness and Neuropsychological Performance in Normal Older Adults and Those with Mild Cognitive Impairment.

Cheng CP, Cheng ST, Tam CW, Chan WC, Chu WC, Lam LC.

Aging Dis. 2018 Dec 4;9(6):1020-1030. doi: 10.14336/AD.2018.0125. eCollection 2018 Dec.


Association between dry eye disease and asthma: a nationwide population-based study.

Huang YC, Chan WC, Wang JD, Fu LS, Tsan YT.

PeerJ. 2018 Dec 5;6:e5941. doi: 10.7717/peerj.5941. eCollection 2018.


Using Gene Expression Profiling to Move Beyond MYC/BCL2 Rearrangements in High-Grade Lymphoma.

Chan WC.

J Clin Oncol. 2019 Jan 20;37(3):175-177. doi: 10.1200/JCO.18.01910. Epub 2018 Dec 3. No abstract available.


Regulation of SOX11 expression through CCND1 and STAT3 in mantle cell lymphoma.

Mohanty A, Sandoval N, Phan A, Nguyen TV, Chen RW, Budde E, Mei M, Popplewell L, Pham LV, Kwak LW, Weisenburger DD, Rosen ST, Chan WC, Müschen M, Ngo VN.

Blood. 2019 Jan 24;133(4):306-318. doi: 10.1182/blood-2018-05-851667. Epub 2018 Dec 10.


Synthesis of Patient-Specific Nanomaterials.

Lazarovits J, Chen YY, Song F, Ngo W, Tavares AJ, Zhang YN, Audet J, Tang B, Lin Q, Tleugabulova MC, Wilhelm S, Krieger JR, Mallevaey T, Chan WCW.

Nano Lett. 2019 Jan 9;19(1):116-123. doi: 10.1021/acs.nanolett.8b03434. Epub 2018 Dec 28.


Total Synthesis of the Reported Structure of Stresgenin B Enabled by the Diastereoselective Cyanation of an Oxocarbenium.

Chan WC, Koide K.

Org Lett. 2018 Dec 21;20(24):7798-7802. doi: 10.1021/acs.orglett.8b03219. Epub 2018 Dec 7.


Electroacupuncture for tapering off long-term benzodiazepine use: A randomized controlled trial.

Yeung WF, Chung KF, Zhang ZJ, Zhang SP, Chan WC, Ng RM, Chan CL, Ho LM, Yu BY, Chau JC, Lau NC, Lao LX.

J Psychiatr Res. 2019 Feb;109:59-67. doi: 10.1016/j.jpsychires.2018.11.015. Epub 2018 Nov 22.


Psychophysiological effects of Dance Movement Therapy and physical exercise on older adults with mild dementia: A randomized controlled trial.

Ho RTH, Fong TCT, Chan WC, Kwan JSK, Chiu PKC, Yau JCY, Lam LCW.

J Gerontol B Psychol Sci Soc Sci. 2018 Nov 28. doi: 10.1093/geronb/gby145. [Epub ahead of print]


One-year real-world outcomes of ranibizumab 0.5 mg treatment in Taiwanese patients with polypoidal choroidal vasculopathy: a subgroup analysis of the REAL study.

Chen SN, Cheng CK, Yeung L, Chen JT, Chan WC, Liu JH, Sheu SJ, Wu WC, Lai CC.

Int J Ophthalmol. 2018 Nov 18;11(11):1802-1808. doi: 10.18240/ijo.2018.11.11. eCollection 2018.


Daedal Facets of Splice Modulator Optimization.

Chan WC, León B, Krug KA, Patel A, La Clair JJ, Burkart MD.

ACS Med Chem Lett. 2018 Oct 29;9(11):1070-1072. doi: 10.1021/acsmedchemlett.8b00456. eCollection 2018 Nov 8.


CD8α+ Dendritic Cells Dictate Leukemia-Specific CD8+ T Cell Fates.

Kline DE, MacNabb BW, Chen X, Chan WC, Fosco D, Kline J.

J Immunol. 2018 Dec 15;201(12):3759-3769. doi: 10.4049/jimmunol.1801184. Epub 2018 Nov 12.


Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts.

Liu X, Cao M, Palomares M, Wu X, Li A, Yan W, Fong MY, Chan WC, Wang SE.

Breast Cancer Res. 2018 Oct 22;20(1):127. doi: 10.1186/s13058-018-1059-y.


Interferon-α2a treatment for refractory Behçet's disease.

Lai YJ, Chan WC.

Taiwan J Ophthalmol. 2018 Jul-Sep;8(3):168-172. doi: 10.4103/tjo.tjo_99_17.


Recommendation of using systemic anti-tumor necrosis factor-alpha for the treatment of noninfectious uveitis in Taiwan.

Hwang DK, Hwang YS, Tsai ML, Lin CJ, Chan WC, Chang YC, Chen DY, Hsieh TY, Sheu SJ, Lin CP.

Taiwan J Ophthalmol. 2018 Jul-Sep;8(3):117-120. doi: 10.4103/tjo.tjo_32_18. Review.


Molecular classification of primary mediastinal large B-cell lymphoma using routinely available tissue specimens.

Mottok A, Wright G, Rosenwald A, Ott G, Ramsower C, Campo E, Braziel RM, Delabie J, Weisenburger DD, Song JY, Chan WC, Cook JR, Fu K, Greiner T, Smeland E, Holte H, Savage KJ, Glinsmann-Gibson BJ, Gascoyne RD, Staudt LM, Jaffe ES, Connors JM, Scott DW, Steidl C, Rimsza LM.

Blood. 2018 Nov 29;132(22):2401-2405. doi: 10.1182/blood-2018-05-851154. Epub 2018 Sep 26.


Overexpression of CXCR4 synergizes with LL-37 in the metastasis of breast cancer cells.

Pan WL, Wang Y, Hao Y, Wong JH, Chan WC, Wan DC, Ng TB.

Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3837-3846. doi: 10.1016/j.bbadis.2018.09.008. Epub 2018 Sep 9.


Comparison of Total Joint Replacement Rate Between Patients With Hemophilia A and Patients With Hemophilia B: A Population-Based and Retrospective Cohort Study.

Lin WY, Wang JD, Tsan YT, Chan WC, Tong KM, Chang ST, Cheng YY.

Clin Appl Thromb Hemost. 2018 Sep 13:1076029618794294. doi: 10.1177/1076029618794294. [Epub ahead of print]


The miR-17~92 cluster activates mTORC1 in mantle cell lymphoma by targeting multiple regulators in the STK11/AMPK/TSC/mTOR pathway.

Jiang C, Bi C, Jiang X, Tian T, Huang X, Wang C, Fernandez MR, Iqbal J, Chan WC, McKeithan TW, Lewis RE, Fu K.

Br J Haematol. 2019 May;185(3):616-620. doi: 10.1111/bjh.15591. Epub 2018 Sep 10. No abstract available.


Choroidal metastasis from esophageal squamous cell carcinoma.

Chang SY, Tsai SH, Chen LJ, Chan WC, Tsao YP.

Taiwan J Ophthalmol. 2018 Apr-Jun;8(2):104-107. doi: 10.4103/tjo.tjo_80_17.


Inhibiting the integrated stress response pathway prevents aberrant chondrocyte differentiation thereby alleviating chondrodysplasia.

Wang C, Tan Z, Niu B, Tsang KY, Tai A, Chan WCW, Lo RLK, Leung KKH, Dung NWF, Itoh N, Zhang MQ, Chan D, Cheah KSE.

Elife. 2018 Jul 19;7. pii: e37673. doi: 10.7554/eLife.37673.


Quantifying the Ligand-Coated Nanoparticle Delivery to Cancer Cells in Solid Tumors.

Dai Q, Wilhelm S, Ding D, Syed AM, Sindhwani S, Zhang Y, Chen YY, MacMillan P, Chan WCW.

ACS Nano. 2018 Aug 28;12(8):8423-8435. doi: 10.1021/acsnano.8b03900. Epub 2018 Jul 26.


Perceived challenges in pediatric palliative care among doctors and nurses in Hong Kong.

Chan WCH, Wong KLY, Leung MMM, Lin MKY.

Death Stud. 2019;43(6):372-380. doi: 10.1080/07481187.2018.1478912. Epub 2018 Jul 17.


Disease Progression in a Patient With Indolent T-Cell Lymphoproliferative Disease of the Gastrointestinal Tract.

Perry AM, Bailey NG, Bonnett M, Jaffe ES, Chan WC.

Int J Surg Pathol. 2019 Feb;27(1):102-107. doi: 10.1177/1066896918785985. Epub 2018 Jul 9.


A multiprotein supercomplex controlling oncogenic signalling in lymphoma.

Phelan JD, Young RM, Webster DE, Roulland S, Wright GW, Kasbekar M, Shaffer AL 3rd, Ceribelli M, Wang JQ, Schmitz R, Nakagawa M, Bachy E, Huang DW, Ji Y, Chen L, Yang Y, Zhao H, Yu X, Xu W, Palisoc MM, Valadez RR, Davies-Hill T, Wilson WH, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, Delabie J, Rimsza LM, Rodriguez FJ, Estephan F, Holdhoff M, Kruhlak MJ, Hewitt SM, Thomas CJ, Pittaluga S, Oellerich T, Staudt LM.

Nature. 2018 Aug;560(7718):387-391. doi: 10.1038/s41586-018-0290-0. Epub 2018 Jun 20.


Association of Daily Intellectual Activities With Lower Risk of Incident Dementia Among Older Chinese Adults.

Lee ATC, Richards M, Chan WC, Chiu HFK, Lee RSY, Lam LCW.

JAMA Psychiatry. 2018 Jul 1;75(7):697-703. doi: 10.1001/jamapsychiatry.2018.0657.


Is general practice identification of prior cardiovascular disease at the time of CVD risk assessment accurate and does it matter?

Wells S, Poppe K, Selak V, Kerr A, Pylypchuk R, Wu B, Chan WC, Grey C, Mehta S, Gentles DG, Jackson R.

N Z Med J. 2018 May 18;131(1475):10-20.


Multi-Kinase Inhibitor with Anti-p38γ Activity in Cutaneous T-Cell Lymphoma.

Zhang XH, Nam S, Wu J, Chen CH, Liu X, Li H, McKeithan T, Gong Q, Chan WC, Yin HH, Yuan YC, Pillai R, Querfeld C, Horne D, Chen Y, Rosen ST.

J Invest Dermatol. 2018 Nov;138(11):2377-2387. doi: 10.1016/j.jid.2018.04.030. Epub 2018 Jul 14.


MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease.

Bhanvadia RR, VanOpstall C, Brechka H, Barashi NS, Gillard M, McAuley EM, Vasquez JM, Paner G, Chan WC, Andrade J, De Marzo AM, Han M, Szmulewitz RZ, Vander Griend DJ.

Clin Cancer Res. 2018 Aug 1;24(15):3668-3680. doi: 10.1158/1078-0432.CCR-17-3673. Epub 2018 May 1.


Self-competence in death work among health and social care workers: a region-wide survey in Hong Kong.

Cheung JTK, Au DWH, Chan WCH, Chan JHY, Ng K, Woo J.

BMC Palliat Care. 2018 Apr 20;17(1):65. doi: 10.1186/s12904-018-0317-1.


Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target.

Dufva O, Kankainen M, Kelkka T, Sekiguchi N, Awad SA, Eldfors S, Yadav B, Kuusanmäki H, Malani D, Andersson EI, Pietarinen P, Saikko L, Kovanen PE, Ojala T, Lee DA, Loughran TP Jr, Nakazawa H, Suzumiya J, Suzuki R, Ko YH, Kim WS, Chuang SS, Aittokallio T, Chan WC, Ohshima K, Ishida F, Mustjoki S.

Nat Commun. 2018 Apr 19;9(1):1567. doi: 10.1038/s41467-018-03987-2.


Early onset of disc degeneration in SM/J mice is associated with changes in ion transport systems and fibrotic events.

Zhang Y, Xiong C, Kudelko M, Li Y, Wang C, Wong YL, Tam V, Rai MF, Cheverud J, Lawson HA, Sandell L, Chan WCW, Cheah KSE, Sham PC, Chan D.

Matrix Biol. 2018 Sep;70:123-139. doi: 10.1016/j.matbio.2018.03.024. Epub 2018 Apr 9.


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