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A tripartite cooperative mechanism confers resistance of the protein kinase A catalytic subunit to dephosphorylation.

Chan TO, Armen RS, Yadav S, Shah S, Zhang J, Tiegs BC, Keny N, Blumhof B, Deshpande DA, Rodeck U, Penn RB.

J Biol Chem. 2020 Jan 21. pii: jbc.RA119.010004. doi: 10.1074/jbc.RA119.010004. [Epub ahead of print]


Cyber Disaster Medicine: A New Frontier for Emergency Medicine.

Dameff C, Farah J, Killeen J, Chan T.

Ann Emerg Med. 2020 Jan 17. pii: S0196-0644(19)31381-2. doi: 10.1016/j.annemergmed.2019.11.011. [Epub ahead of print] No abstract available.


Predictors of postoperative respiratory complications in children undergoing adenotonsillectomy.

Katz SL, Monsour A, Barrowman N, Hoey L, Bromwich M, Momoli F, Chan T, Goldberg R, Patel A, Yin L, Murto K.

J Clin Sleep Med. 2020 Jan 15;16(1):41-48. doi: 10.5664/jcsm.8118. Epub 2019 Nov 27.


Leaf carbon and water status control stomatal and non-stomatal limitations of photosynthesis in trees.

Salmon Y, Lintunen A, Dayet A, Chan T, Dewar R, Vesala T, Hölttä T.

New Phytol. 2020 Jan 18. doi: 10.1111/nph.16436. [Epub ahead of print]


Rapid Differentiation of Asian and American Ginseng by Differential Ion Mobility Spectrometry-Tandem Mass Spectrometry Using Stepwise Modulation of Gas Modifier Concentration.

Wu R, Chen X, Wu WJ, Wang Z, Wong YE, Hung YW, Wong HT, Yang M, Zhang F, Chan TD.

J Am Soc Mass Spectrom. 2019 Nov 1;30(11):2212-2221.


A drone delivery network for antiepileptic drugs: a framework and modelling case study in a low-income country.

Mateen FJ, Leung KHB, Vogel AC, Cissé AF, Chan TCY.

Trans R Soc Trop Med Hyg. 2020 Jan 14. pii: trz131. doi: 10.1093/trstmh/trz131. [Epub ahead of print]


Clinical Toxicology Expert Reviewers 2019.

Seifert SA, Buckley N, Seger D, Thomas S, Chan B, Chan TYK, Kirschner RI, Megarbane B, Oakes J, Wilks M, Mullins M, Allister Vale J.

Clin Toxicol (Phila). 2020 Mar;58(3):e1-e3. doi: 10.1080/15563650.2020.1712900. Epub 2020 Jan 14. No abstract available.


A Targeted Gene Panel That Covers Coding, Non-coding and Short Tandem Repeat Regions Improves the Diagnosis of Patients With Neurodegenerative Diseases.

Yu AC, Yim AK, Chan AY, Yuen LYP, Au WC, Cheng THT, Lin X, Li JW, Chan LWL, Mok VCT, Chan TF, Chan HYE.

Front Neurosci. 2019 Dec 11;13:1324. doi: 10.3389/fnins.2019.01324. eCollection 2019.


A crustacean annotated transcriptome (CAT) database.

Nong W, Chai ZYH, Jiang X, Qin J, Ma KY, Chan KM, Chan TF, Chow BKC, Kwan HS, Wong CKC, Qiu JW, Hui JHL, Chu KH.

BMC Genomics. 2020 Jan 9;21(1):32. doi: 10.1186/s12864-019-6433-3.


Amplification-driven BCL6-suppressed cytostasis is mediated by transrepression of FOXO3 and post-translational modifications of FOXO3 in urinary bladder urothelial carcinoma.

Wu WR, Lin JT, Pan CT, Chan TC, Liu CL, Wu WJ, Sheu JJ, Yeh BW, Huang SK, Jhung JY, Hsiao MS, Li CF, Shiue YL.

Theranostics. 2020 Jan 1;10(2):707-724. doi: 10.7150/thno.39018. eCollection 2020.


U.S. Optometrists' Reported Practices and Perceived Barriers for Low Vision Care for Mild Visual Loss.

Malkin AG, Ross NC, Chan TL, Protosow K, Bittner AK.

Optom Vis Sci. 2020 Jan;97(1):45-51. doi: 10.1097/OPX.0000000000001468.


Quantification of Anionic Redox Chemistry in a Prototype Na-Rich Layered Oxide.

Hu Y, Liu T, Cheng C, Yan Y, Ding M, Chan TS, Guo J, Zhang L.

ACS Appl Mater Interfaces. 2020 Jan 22;12(3):3617-3623. doi: 10.1021/acsami.9b19204. Epub 2020 Jan 10.


Analysis of Soybean Long Non-coding RNAs Reveals a Subset of Small Peptide-Coding Transcripts.

Lin X, Lin W, Ku YS, Wong FL, Li MW, Lam HM, Ngai SM, Chan TF.

Plant Physiol. 2019 Dec 27. pii: pp.01324.2019. doi: 10.1104/pp.19.01324. [Epub ahead of print]


The Impact of Lifestyle Changes on Cardiometabolic Health in Modernizing China: A Tale of Three Gorges in the Yangtze River.

Woo KS, Hu YJ, Chook P, Wei AN, Wu MJ, Li L, Woo J, Chan TYK, Cheng WKF, Celermajer DS.

Metab Syndr Relat Disord. 2019 Dec 23. doi: 10.1089/met.2019.0027. [Epub ahead of print]


Long-Term Exposure to Ambient Fine Particulate Matter (PM2.5) and Lung Function in Children, Adolescents, and Young Adults: A Longitudinal Cohort Study.

Guo C, Hoek G, Chang LY, Bo Y, Lin C, Huang B, Chan TC, Tam T, Lau AKH, Lao XQ.

Environ Health Perspect. 2019 Dec;127(12):127008. doi: 10.1289/EHP5220. Epub 2019 Dec 24.


Transcriptomic signatures related to the obesity paradox in patients with clear cell renal cell carcinoma: a cohort study.

Sanchez A, Furberg H, Kuo F, Vuong L, Ged Y, Patil S, Ostrovnaya I, Petruzella S, Reising A, Patel P, Mano R, Coleman J, Russo P, Liu CH, Dannenberg AJ, Chan TA, Motzer R, Voss MH, Hakimi AA.

Lancet Oncol. 2019 Dec 20. pii: S1470-2045(19)30797-1. doi: 10.1016/S1470-2045(19)30797-1. [Epub ahead of print]


Propagating ice front induces gas bursts and ultrasonic acoustic emissions from freezing xylem.

Lintunen A, Losso A, Aalto J, Chan T, Hölttä T, Mayr S.

Tree Physiol. 2019 Dec 19. pii: tpz123. doi: 10.1093/treephys/tpz123. [Epub ahead of print]


Curated Collections for Educators: Five Key Papers on Clinical Teaching.

Quinn A, Gottlieb M, Chan TM, Nickson CP, Mitzman J, Natesan S, Stehman C, Young A, Messman A.

Cureus. 2019 Nov 6;11(11):e6084. doi: 10.7759/cureus.6084.


Implementation of a Clinical Decision Support Tool to Improve Antibiotic IV-to-Oral Conversion Rates at a Community Academic Hospital.

Kan T, Kwan D, Chan T, Das P, Raybardhan S.

Can J Hosp Pharm. 2019 Nov-Dec;72(6):455-461. Epub 2019 Dec 1.


Seismic mitigation of steel modular building structures through innovative inter-modular connections.

Sendanayake SV, Thambiratnam DP, Perera N, Chan T, Aghdamy S.

Heliyon. 2019 Nov 14;5(11):e02751. doi: 10.1016/j.heliyon.2019.e02751. eCollection 2019 Nov.


Expression and prognostic utility of SSX2IP in patients with nasopharyngeal carcinoma.

Chang SL, Lee SW, Yang SF, Chien CC, Chan TC, Chen TJ, Yang CC, Li CF, Wei YC.

APMIS. 2019 Dec 14. doi: 10.1111/apm.13023. [Epub ahead of print]


Injury patterns of mass casualty incidents involving high-speed passenger ferries presenting to accident and emergency departments in Hong Kong: a retrospective review.

Lam RPK, Wong RTM, Lau EHY, Wong KW, Cheung ACK, Chaang VK, Chen L, Tsang TC, Chan TK, Chee PPY, Ko FHF, Leung CS, Yang SM.

Injury. 2019 Dec 2. pii: S0020-1383(19)30766-1. doi: 10.1016/j.injury.2019.12.001. [Epub ahead of print]


B Cell Abnormalities in Systemic Lupus Erythematosus and Lupus Nephritis-Role in Pathogenesis and Effect of Immunosuppressive Treatments.

Yap DYH, Chan TM.

Int J Mol Sci. 2019 Dec 10;20(24). pii: E6231. doi: 10.3390/ijms20246231. Review.


Social media in knowledge translation and education for physicians and trainees: a scoping review.

Chan TM, Dzara K, Dimeo SP, Bhalerao A, Maggio LA.

Perspect Med Educ. 2019 Dec 13. doi: 10.1007/s40037-019-00542-7. [Epub ahead of print] Review.


A Review on Evidence-Based Treatments for Meibomian Gland Dysfunction.

Lam PY, Shih KC, Fong PY, Chan TCY, Ng AL, Jhanji V, Tong L.

Eye Contact Lens. 2020 Jan;46(1):3-16. doi: 10.1097/ICL.0000000000000680.


Putative Drivers of Aggressiveness in TCEB1-mutant Renal Cell Carcinoma: An Emerging Entity with Variable Clinical Course.

DiNatale RG, Gorelick AN, Makarov V, Blum KA, Silagy AW, Freeman B, Chowell D, Marcon J, Mano R, Sanchez A, Attalla K, Weng S, Voss M, Motzer RJ, Russo P, Coleman JA, Reuter VE, Chen YB, Chan TA, Reznik E, Tickoo SK, Hakimi AA.

Eur Urol Focus. 2019 Dec 6. pii: S2405-4569(19)30354-2. doi: 10.1016/j.euf.2019.11.013. [Epub ahead of print]


Individual- and community-level shifts in mortality patterns during the January 2016 East Asia cold wave associated with a super El Niño event: Empirical evidence in Hong Kong.

Chak Ho H, Chan TC, Xu Z, Huang C, Li C.

Sci Total Environ. 2019 Nov 22:135050. doi: 10.1016/j.scitotenv.2019.135050. [Epub ahead of print]


Experimental modeling of cornea wound healing in diabetes: clinical applications and beyond.

Bu Y, Shih KC, Kwok SS, Chan YK, Lo AC, Chan TCY, Jhanji V, Tong L.

BMJ Open Diabetes Res Care. 2019 Nov 27;7(1):e000779. doi: 10.1136/bmjdrc-2019-000779. eCollection 2019. Review.


Assessing effects of personal behaviors and environmental exposure on asthma episodes: a diary-based approach.

Chan TC, Hu TH, Chu YH, Hwang JS.

BMC Pulm Med. 2019 Dec 2;19(1):231. doi: 10.1186/s12890-019-0998-0.


Making Decisions in the Era of the Clinical Decision Rule: How Emergency Physicians Use Clinical Decision Rules.

Chan TM, Mercuri M, Turcotte M, Gardiner E, Sherbino J, de Wit K.

Acad Med. 2019 Nov 26. doi: 10.1097/ACM.0000000000003098. [Epub ahead of print]


A Cohesin Subunit Variant Identified from a Peripheral Sclerocornea Pedigree.

Zhang BN, Chan TCY, Tam POS, Liu Y, Pang CP, Jhanji V, Chen LJ, Chu WK.

Dis Markers. 2019 Nov 12;2019:8781524. doi: 10.1155/2019/8781524. eCollection 2019.


Characterization of Hepatocellular Carcinoma Cell Lines Using a Fractionation-Then-Sequencing Approach Reveals Nuclear-Enriched HCC-Associated lncRNAs.

Chow EY, Zhang J, Qin H, Chan TF.

Front Genet. 2019 Nov 8;10:1081. doi: 10.3389/fgene.2019.01081. eCollection 2019.


Hydrothermal Synthesis of Ruthenium Nanoparticles with a Metallic Core and a Ruthenium Carbide Shell for Low-Temperature Activation of CO2 to Methane.

Cored J, García-Ortiz A, Iborra S, Climent MJ, Liu L, Chuang CH, Chan TS, Escudero C, Concepción P, Corma A.

J Am Chem Soc. 2019 Dec 11;141(49):19304-19311. doi: 10.1021/jacs.9b07088. Epub 2019 Nov 27.


Safe sexual behaviors intention among female youth: The construction on extended theory of planned behavior.

Tseng YH, Cheng CP, Kuo SH, Hou WL, Chan TF, Chou FH.

J Adv Nurs. 2019 Nov 27. doi: 10.1111/jan.14277. [Epub ahead of print]


An international, interprofessional investigation of the self-reported podcast listening habits of emergency clinicians: A METRIQ Study.

Thoma B, Goerzen S, Horeczko T, Roland D, Tagg A, Chan TM, Bruijns S, Riddell J; METRIQ Podcast Study Collaborators.

CJEM. 2019 Nov 25:1-6. doi: 10.1017/cem.2019.427. [Epub ahead of print]


A survey of current use, dilemma and outlook of antenatal ultrasonography in Taiwan.

Ker CR, Kuo YL, Chan TF.

Taiwan J Obstet Gynecol. 2019 Nov;58(6):820-826. doi: 10.1016/j.tjog.2019.09.017.


Developing Residents as Medical Educators via the McMaster Multidisciplinary Academic Day Planning Committee.

Chorley AG, Walton JM, Montesanto B, Chan TM.

Cureus. 2019 Oct 7;11(10):e5855. doi: 10.7759/cureus.5855.


Treatment for occult breast cancer: A propensity score analysis of the National Cancer Database.

Tsai C, Zhao B, Chan T, Blair SL.

Am J Surg. 2019 Nov 11. pii: S0002-9610(19)31361-3. doi: 10.1016/j.amjsurg.2019.11.023. [Epub ahead of print]


A Black Phosphorus-Graphite Composite Anode for Li-/Na-/K-Ion Batteries.

Jin H, Wang H, Qi Z, Bin DS, Zhang T, Wan Y, Chen J, Chuang C, Lu YR, Chan TS, Ju H, Cao AM, Yan W, Wu X, Ji H, Wan LJ.

Angew Chem Int Ed Engl. 2019 Nov 21. doi: 10.1002/anie.201913129. [Epub ahead of print]


Patient and health care system characteristics are associated with delayed treatment of tuberculosis cases in Taiwan.

Chen CC, Chiang PH, Chen YH, Fan IC, Chan TC.

BMC Health Serv Res. 2019 Nov 19;19(1):846. doi: 10.1186/s12913-019-4702-0.


Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing.

Laks E, McPherson A, Zahn H, Lai D, Steif A, Brimhall J, Biele J, Wang B, Masud T, Ting J, Grewal D, Nielsen C, Leung S, Bojilova V, Smith M, Golovko O, Poon S, Eirew P, Kabeer F, Ruiz de Algara T, Lee SR, Taghiyar MJ, Huebner C, Ngo J, Chan T, Vatrt-Watts S, Walters P, Abrar N, Chan S, Wiens M, Martin L, Scott RW, Underhill TM, Chavez E, Steidl C, Da Costa D, Ma Y, Coope RJN, Corbett R, Pleasance S, Moore R, Mungall AJ, Mar C, Cafferty F, Gelmon K, Chia S; CRUK IMAXT Grand Challenge Team, Marra MA, Hansen C, Shah SP, Aparicio S.

Cell. 2019 Nov 14;179(5):1207-1221.e22. doi: 10.1016/j.cell.2019.10.026.


Case Report: The first probable Hong Kong Chinese case of LPIN1-related acute recurrent rhabdomyolysis in a boy with two novel variants.

Yim SW, Chan TYC, Belaramani KM, Man SS, Wong FCK, Chen SPL, Lee HHC, Mak CM, Ching CK.

F1000Res. 2019 Sep 2;8:1566. doi: 10.12688/f1000research.20343.1. eCollection 2019.


Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness.

Patel VL, Busch EL, Friebel TM, Cronin A, Leslie G, McGuffog L, Adlard J, Agata S, Agnarsson BA, Ahmed M, Aittomäki K, Alducci E, Andrulis IL, Arason A, Arnold N, Artioli G, Arver B, Auber B, Azzollini J, Balmaña J, Barkardottir RB, Barnes DR, Barroso A, Barrowdale D, Belotti M, Benitez J, Bertelsen B, Blok MJ, Bodrogi I, Bonadona V, Bonanni B, Bondavalli D, Boonen SE, Borde J, Borg A, Bradbury AR, Brady A, Brewer C, Brunet J, Buecher B, Buys SS, Cabezas-Camarero S, Caldés T, Caliebe A, Caligo MA, Calvello M, Campbell IG, Carnevali I, Carrasco E, Chan TL, Chu ATW, Chung WK, Claes KBM, Collaborators GS, Collaborators E, Cook J, Cortesi L, Couch FJ, Daly MB, Damante G, Darder E, Davidson R, de la Hoya M, Puppa LD, Dennis J, Díez O, Ding YC, Ditsch N, Domchek SM, Donaldson A, Dworniczak B, Easton DF, Eccles DM, Eeles RA, Ehrencrona H, Ejlertsen B, Engel C, Evans DG, Faivre L, Faust U, Feliubadaló L, Foretova L, Fostira F, Fountzilas G, Frost D, García-Barberán V, Garre P, Gauthier-Villars M, Géczi L, Gehrig A, Gerdes AM, Gesta P, Giannini G, Glendon G, Godwin AK, Goldgar DE, Greene MH, Gutierrez-Barrera AM, Hahnen E, Hamann U, Hauke J, Herold N, Hogervorst FBL, Honisch E, Hopper JL, Hulick PJ, Investigators K, Investigators H, Izatt L, Jager A, James P, Janavicius R, Jensen UB, Jensen TD, Johannsson OT, John EM, Joseph V, Kang E, Kast K, Kiiski JI, Kim SW, Kim Z, Ko KP, Konstantopoulou I, Kramer G, Krogh L, Kruse TA, Kwong A, Larsen M, Lasset C, Lautrup C, Lazaro C, Lee J, Lee JW, Lee MH, Lemke J, Lesueur F, Liljegren A, Lindblom A, Llovet P, Lopez-Fernández A, Lopez-Perolio I, Lorca V, Loud JT, Ma ESK, Mai PL, Manoukian S, Mari V, Martin L, Matricardi L, Mebirouk N, Medici V, Meijers-Heijboer HEJ, Meindl A, Mensenkamp AR, Miller C, Gomes DM, Montagna M, Mooij TM, Moserle L, Mouret-Fourme E, Mulligan AM, Nathanson KL, Navratilova M, Nevanlinna H, Niederacher D, Nielsen FCC, Nikitina-Zake L, Offit K, Olah E, Olopade OI, Ong KR, Osorio A, Ott CE, Palli D, Park SK, Parsons MT, Pedersen IS, Peissel B, Peixoto A, Pérez-Segura P, Peterlongo P, Petersen AH, Porteous ME, Pujana MA, Radice P, Ramser J, Rantala J, Rashid MU, Rhiem K, Rizzolo P, Robson ME, Rookus MA, Rossing CM, Ruddy KJ, Santos C, Saule C, Scarpitta R, Schmutzler RK, Schuster H, Senter L, Seynaeve CM, Shah PD, Sharma P, Shin VY, Silvestri V, Simard J, Singer CF, Skytte AB, Snape K, Solano AR, Soucy P, Southey MC, Spurdle AB, Steele L, Steinemann D, Stoppa-Lyonnet D, Stradella A, Sunde L, Sutter C, Tan YY, Teixeira MR, Teo SH, Thomassen M, Tibiletti MG, Tischkowitz M, Tognazzo S, Toland AE, Tommasi S, Torres D, Toss A, Trainer AH, Tung N, van Asperen CJ, van der Baan FH, van der Kolk LE, van der Luijt RB, van Hest LP, Varesco L, Varon-Mateeva R, Viel A, Vierstrate J, Villa R, von Wachenfeldt A, Wagner P, Wang-Gohrke S, Wappenschmidt B, Weitzel JN, Wieme G, Yadav S, Yannoukakos D, Yoon SY, Zanzottera C, Zorn KK, D'Amico AV, Freedman ML, Pomerantz MM, Chenevix-Trench G, Antoniou AC, Neuhausen SL, Ottini L, Nielsen HR, Rebbeck TR.

Cancer Res. 2019 Nov 13. doi: 10.1158/0008-5472.CAN-19-1840. [Epub ahead of print]


Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy.

Chowell D, Krishna C, Pierini F, Makarov V, Rizvi NA, Kuo F, Morris LGT, Riaz N, Lenz TL, Chan TA.

Nat Med. 2019 Nov;25(11):1715-1720. doi: 10.1038/s41591-019-0639-4. Epub 2019 Nov 7.


Organic Matter Amendment and Plant Colonization Drive Mineral Weathering, Organic Carbon Sequestration, and Water-Stable Aggregation in Magnetite Fe Ore Tailings.

Wu S, Liu Y, Bougoure JJ, Southam G, Chan TS, Lu YR, Haw SC, Nguyen TAH, You F, Huang L.

Environ Sci Technol. 2019 Dec 3;53(23):13720-13731. doi: 10.1021/acs.est.9b04526. Epub 2019 Nov 20.


Impact of emotion dysregulation and cognitive insight on psychotic and depressive symptoms during the early course of schizophrenia spectrum disorders.

Liu J, Chan TCT, Chong SA, Subramaniam M, Mahendran R.

Early Interv Psychiatry. 2019 Nov 6. doi: 10.1111/eip.12895. [Epub ahead of print]


Potential utility of metagenomic sequencing for improving etiologic diagnosis of infective endocarditis.

Chan WS, Au CH, Leung HC, Ho DN, Li D, Chan TL, Lam TW, Ma ES, Tang BS.

Future Cardiol. 2019 Nov;15(6):411-424. doi: 10.2217/fca-2018-0088. Epub 2019 Nov 6.


Obliquely Deposited Titanium Nitride Nanorod Arrays as Surface-Enhanced Raman Scattering Substrates.

Jen YJ, Lin MJ, Cheang HL, Chan TL.

Sensors (Basel). 2019 Nov 2;19(21). pii: E4765. doi: 10.3390/s19214765.


Advance Care Planning: A Communitarian Approach?

Chan TE.

J Law Med. 2019 Jul;26(4):896-921.


Transcription Factor Elf3 Modulates Vasopressin-Induced Aquaporin-2 Gene Expression in Kidney Collecting Duct Cells.

Lin ST, Ma CC, Kuo KT, Su YF, Wang WL, Chan TH, Su SH, Weng SC, Yang CH, Lin SL, Yu MJ.

Front Physiol. 2019 Oct 18;10:1308. doi: 10.3389/fphys.2019.01308. eCollection 2019.

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