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Maternal glycemia during pregnancy and offspring abdominal adiposity measured by MRI in the neonatal period and preschool years: The Growing Up in Singapore Towards healthy Outcomes (GUSTO) prospective mother-offspring birth cohort study.

Tint MT, Sadananthan SA, Soh SE, Aris IM, Michael N, Tan KH, Shek LPC, Yap F, Gluckman PD, Chong YS, Godfrey KM, Velan SS, Chan SY, Eriksson JG, Fortier MV, Zhang C, Lee YS.

Am J Clin Nutr. 2020 Mar 27. pii: nqaa055. doi: 10.1093/ajcn/nqaa055. [Epub ahead of print]


Reasons for voriconazole prophylaxis discontinuation in allogeneic hematopoietic cell transplant recipients: A real-life paradigm.

Chan SY, Hughes RM, Woo K, Perales MA, Neofytos D, Papanicolaou G.

Med Mycol. 2020 Mar 14. pii: myaa008. doi: 10.1093/mmy/myaa008. [Epub ahead of print]


Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension.

Saygin D, Tabib T, Bittar HET, Valenzi E, Sembrat J, Chan SY, Rojas M, Lafyatis R.

Pulm Circ. 2020 Feb 28;10(1). pii: ???. doi: 10.1177/2045894020908782. eCollection 2020 Jan-Mar.


Is breastfeeding associated with later child eating behaviours?

Pang WW, McCrickerd K, Quah PL, Fogel A, Aris IM, Yuan WL, Fok D, Chua MC, Lim SB, Shek LP, Chan SY, Tan KH, Yap F, Godfrey KM, Meaney MJ, Wlodek ME, Eriksson JG, Kramer MS, Forde CG, Chong MF, Chong YS.

Appetite. 2020 Mar 7;150:104653. doi: 10.1016/j.appet.2020.104653. [Epub ahead of print]


New flavonoid-based compound synthesis strategy for antihypertensive drug development.

Loh YC, Chan SY, Tew WY, Oo CW, Yam MF.

Life Sci. 2020 May 15;249:117512. doi: 10.1016/j.lfs.2020.117512. Epub 2020 Mar 5. Review.


Lower DLco% identifies exercise pulmonary hypertension in patients with parenchymal lung disease referred for dyspnea.

Zou RH, Wallace WD, Nouraie SM, Chan SY, Risbano MG.

Pulm Circ. 2020 Feb 19;10(1):2045894019891912. doi: 10.1177/2045894019891912. eCollection 2020 Jan-Mar.


Enhanced ultraviolet electroluminescence from ZnO nanoparticles via decoration of partially oxidized Al layer.

Chan SY, Wu SC, Wang CY, Hsu HC.

Opt Express. 2020 Feb 3;28(3):2799-2808. doi: 10.1364/OE.382340.


Outcomes of Pulmonary Arterial Hypertension are Improved in a Specialty Care Center.

Pi H, Kosanovich CM, Handen A, Tao M, Visina J, Vanspeybroeck G, Simon MA, Risbano MG, Desai A, Mathier MA, Rivera-Lebron BN, Nguyen Q, Kliner J, Nouraie M, Chan SY.

Chest. 2020 Feb 25. pii: S0012-3692(20)30334-2. doi: 10.1016/j.chest.2020.01.046. [Epub ahead of print]


Lipoprotein(a) the Insurgent: A New Insight into the Structure, Function, Metabolism, Pathogenicity, and Medications Affecting Lipoprotein(a) Molecule.

Jawi MM, Frohlich J, Chan SY.

J Lipids. 2020 Feb 1;2020:3491764. doi: 10.1155/2020/3491764. eCollection 2020. Review.


Locally invasive and obstructive colonic leiomyosarcoma: a diagnostic and therapeutic challenge.

Wong YC, Chan SY, Yuen KY, Chong LC.

Hong Kong Med J. 2020 Feb;26(1):73-75. doi: 10.12809/hkmj197873. No abstract available.


Thickness of individual layers at the macula and associated factors: the Beijing Eye Study 2011.

Wang Q, Wei WB, Wang YX, Yan YN, Yang JY, Zhou WJ, Chan SY, Xu L, Jonas JB.

BMC Ophthalmol. 2020 Feb 12;20(1):49. doi: 10.1186/s12886-019-1296-6.


Robotic ileal interposition for long ureteric stricture.

Yee CH, Leung DKW, Chiu PKF, Tam MHM, Chan SYS, Teoh JYC, Chan CK, Wong JHM, Ng CF, Hou SSM.

Cent European J Urol. 2019;72(4):425-426. doi: 10.5173/ceju.2019.0037. Epub 2019 Dec 2. No abstract available.


Associations between early-life screen viewing and 24 hour movement behaviours: findings from a longitudinal birth cohort study.

Chen B, Bernard JY, Padmapriya N, Ning Y, Cai S, Lança C, Tan KH, Yap F, Chong YS, Shek L, Godfrey KM, Saw SM, Chan SY, Eriksson JG, Tan CS, Müller-Riemenschneider F.

Lancet Child Adolesc Health. 2020 Mar;4(3):201-209. doi: 10.1016/S2352-4642(19)30424-9. Epub 2020 Jan 28.


Sustainable Dissolution Performance of a Carrier Tailored Electrospun.

Teoh XY, Yeoh Y, Yoong LK, Chan SY.

Pharm Res. 2020 Jan 7;37(2):28. doi: 10.1007/s11095-019-2734-0.


Sleep architecture and homeostasis in children with epilepsy: a neurodevelopmental perspective.

Chan SY.

Dev Med Child Neurol. 2020 Apr;62(4):426-433. doi: 10.1111/dmcn.14437. Epub 2019 Dec 26. Review.


Antenatal sleep quality associated with perinatal outcomes in women of advanced maternal age.

Lee PY, Liu LH, Ho C, Ang AJF, Huang HX, Teoh OH, Tan KH, Lee YS, Yap F, Gooley JJ, Chan SY, Cai S.

Sleep Health. 2020 Feb;6(1):60-64. doi: 10.1016/j.sleh.2019.10.009. Epub 2019 Dec 16.


Recent innovations in artificial skin.

Low ZWK, Li Z, Owh C, Chee PL, Ye E, Dan K, Chan SY, Young DJ, Loh XJ.

Biomater Sci. 2020 Feb 4;8(3):776-797. doi: 10.1039/c9bm01445d. Review.


Revisiting oral fluoropyrimidine with cetuximab in metastatic colorectal cancer: Real-world data in Chinese population.

Lam KO, Fu MC, Lau KS, Lam KM, Choi CW, Chiu WH, Yuen CM, Kwok LH, Tam FK, Chan WL, Chan SY, Ho PY, Leung TW, Lee HF.

World J Gastrointest Oncol. 2019 Nov 15;11(11):1031-1042. doi: 10.4251/wjgo.v11.i11.1031.


A network-based approach to uncover microRNA-mediated disease comorbidities and potential pathobiological implications.

Jin S, Zeng X, Fang J, Lin J, Chan SY, Erzurum SC, Cheng F.

NPJ Syst Biol Appl. 2019 Nov 13;5:41. doi: 10.1038/s41540-019-0115-2. eCollection 2019.


Dopamine and cAMP-regulated phosphoprotein 32 kDa (DARPP-32) and survival in breast cancer: a retrospective analysis of protein and mRNA expression.

Kotecha S, Lebot MN, Sukkarn B, Ball G, Moseley PM, Chan SY, Green AR, Rakha E, Ellis IO, Martin SG, Storr SJ.

Sci Rep. 2019 Nov 18;9(1):16987. doi: 10.1038/s41598-019-53529-z.


Formulation strategy of nitrofurantoin: co-crystal or solid dispersion?

Teoh XY, Bt Mahyuddin FN, Ahmad W, Chan SY.

Pharm Dev Technol. 2020 Feb;25(2):245-251. doi: 10.1080/10837450.2019.1689401. Epub 2019 Nov 25.


PARP1 blockade is synthetically lethal in XRCC1 deficient sporadic epithelial ovarian cancers.

Ali R, Alabdullah M, Alblihy A, Miligy I, Mesquita KA, Chan SY, Moseley P, Rakha EA, Madhusudan S.

Cancer Lett. 2020 Jan 28;469:124-133. doi: 10.1016/j.canlet.2019.10.035. Epub 2019 Oct 24.


Were infections in migrants associated with the resurgence of measles epidemic during 2013-2014 in southern China? A retrospective data analysis.

Chong KC, Hu P, Chan SY, Liang W, Mohammad KN, Sun R, Wang MH, Zee BCY, Shi D, Zheng H.

Int J Infect Dis. 2020 Jan;90:77-83. doi: 10.1016/j.ijid.2019.10.014. Epub 2019 Oct 18.


Levothyroxine to increase live births in euthyroid women with thyroid antibodies trying to conceive: the TABLET RCT.

Dhillon-Smith RK, Middleton LJ, Sunner KK, Cheed V, Baker K, Farrell-Carver S, Bender-Atik R, Agrawal R, Bhatia K, Edi-Osagie E, Ghobara T, Gupta P, Jurkovic D, Khalaf Y, MacLean M, McCabe C, Mulbagal K, Nunes N, Overton C, Quenby S, Rai R, Raine-Fenning N, Robinson L, Ross J, Sizer A, Small R, Tan A, Underwood M, Kilby MD, Boelaert K, Daniels J, Thangaratinam S, Chan SY, Coomarasamy A.

Southampton (UK): NIHR Journals Library; 2019 Oct.


Smart Phone APP to Restore Optimal Weight (SPAROW): protocol for a randomised controlled trial for women with recent gestational diabetes.

Lim K, Chi C, Chan SY, Lim SL, Ang SM, Yoong JS, Tsai C, Wong SR, Yew TW, Tai ES, Yong EL.

BMC Public Health. 2019 Oct 15;19(1):1287. doi: 10.1186/s12889-019-7691-3.


Lrrc7 mutant mice model developmental emotional dysregulation that can be alleviated by mGluR5 allosteric modulation.

Chong CH, Li Q, Mak PHS, Ng CCP, Leung EHW, Tan VH, Chan AKW, McAlonan G, Chan SY.

Transl Psychiatry. 2019 Oct 3;9(1):244. doi: 10.1038/s41398-019-0580-9.


Activation of the Metabolic Master Regulator PPARγ: A Potential PIOneering Therapy for Pulmonary Arterial Hypertension.

Hansmann G, Calvier L, Risbano MG, Chan SY.

Am J Respir Cell Mol Biol. 2020 Feb;62(2):143-156. doi: 10.1165/rcmb.2019-0226PS.


Negative plasma Epstein-Barr virus DNA nasopharyngeal carcinoma in an endemic region and its influence on liquid biopsy screening programmes.

Nicholls JM, Lee VH, Chan SK, Tsang KC, Choi CW, Kwong DL, Lam KO, Chan SY, Tong CC, So TH, Leung TW, Luk MY, Khong PL, Lee AW.

Br J Cancer. 2019 Oct;121(8):690-698. doi: 10.1038/s41416-019-0575-6. Epub 2019 Sep 17.


NFU1, Iron-Sulfur Biogenesis, and Pulmonary Arterial Hypertension: A (Metabolic) Shift in Our Thinking.

Culley MK, Perk D, Chan SY.

Am J Respir Cell Mol Biol. 2020 Feb;62(2):136-138. doi: 10.1165/rcmb.2019-0309ED. No abstract available.


A dual-action chitosan-based nanogel system of triclosan and flurbiprofen for localised treatment of periodontitis.

Aminu N, Chan SY, Yam MF, Toh SM.

Int J Pharm. 2019 Oct 30;570:118659. doi: 10.1016/j.ijpharm.2019.118659. Epub 2019 Sep 4.


Cross-Cultural Adaptation and Validation of the Hong Kong Version of the Knee Injury and Osteoarthritis Outcome Score (HK-KOOS) for Patients with Knee Osteoarthritis.

Cheng ASK, Chan KC, Chan SY, Fan MK, Fung MK, Lee OY, Kwok CTT, Wong JKK.

Occup Ther Int. 2019 Aug 14;2019:8270637. doi: 10.1155/2019/8270637. eCollection 2019.


An enzymatic assay for quantification of inositol in human term placental tissue.

Islam MO, Selvam P, Appukuttan Pillai R, Watkins OC, Chan SY.

Anal Biochem. 2019 Dec 1;586:113409. doi: 10.1016/j.ab.2019.113409. Epub 2019 Aug 27.


Ocular Axial Length and Diabetic Retinopathy: The Kailuan Eye Study.

Wang Q, Wang YX, Wu SL, Chen SH, Yan YN, Yang MC, Yang JY, Zhou WJ, Chan SY, Zhang XH, Yang X, Lei YH, Qin SQ, Chen MX, Jonas JB, Wei WB.

Invest Ophthalmol Vis Sci. 2019 Aug 1;60(10):3689-3695. doi: 10.1167/iovs.19-27531.


Motivations and Barriers Associated With Physician Volunteerism for an International Telemedicine Organization.

Kim EJ, Fox S, Moretti ME, Turner M, Girard TD, Chan SY.

Front Public Health. 2019 Aug 13;7:224. doi: 10.3389/fpubh.2019.00224. eCollection 2019.


Socio-demographic and maternal predictors of adherence to 24-hour movement guidelines in Singaporean children.

Chen B, Bernard JY, Padmapriya N, Yao J, Goh C, Tan KH, Yap F, Chong YS, Shek L, Godfrey KM, Chan SY, Eriksson JG, Müller-Riemenschneider F.

Int J Behav Nutr Phys Act. 2019 Aug 22;16(1):70. doi: 10.1186/s12966-019-0834-1.


Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor β (RARβ).

Liu HJ, Lam HC, Baglini CV, Nijmeh J, Cottrill AA, Chan SY, Henske EP.

Oncogene. 2019 Dec;38(49):7367-7383. doi: 10.1038/s41388-019-0957-5. Epub 2019 Aug 16.


Television viewing and child cognition in a longitudinal birth cohort in Singapore: the role of maternal factors.

Aishworiya R, Cai S, Chen HY, Phua DY, Broekman BFP, Daniel LM, Chong YS, Shek LP, Yap F, Chan SY, Meaney MJ, Law EC.

BMC Pediatr. 2019 Aug 16;19(1):286. doi: 10.1186/s12887-019-1651-z.


Development of a prediction model for breast cancer based on the national cancer registry in Taiwan.

Huang CC, Chan SY, Lee WC, Chiang CJ, Lu TP, Cheng SH.

Breast Cancer Res. 2019 Aug 13;21(1):92. doi: 10.1186/s13058-019-1172-6.


ERCC1 Is a Predictor of Anthracycline Resistance and Taxane Sensitivity in Early Stage or Locally Advanced Breast Cancers.

Abdel-Fatah TMA, Ali R, Sadiq M, Moseley PM, Mesquita KA, Ball G, Green AR, Rakha EA, Chan SYT, Madhusudan S.

Cancers (Basel). 2019 Aug 10;11(8). pii: E1149. doi: 10.3390/cancers11081149.


Myo-inositol alters 13C-labeled fatty acid metabolism in human placental explants.

Watkins OC, Islam MO, Selvam P, Pillai RA, Cazenave-Gassiot A, Bendt AK, Karnani N, Godfrey KM, Lewis RM, Wenk MR, Chan SY.

J Endocrinol. 2019 Aug 1. pii: JOE-19-0267.R1. doi: 10.1530/JOE-19-0267. [Epub ahead of print]


Advancing Care for Head and Neck Cancers in a Multidisciplinary Tumour Board in the East.

Lee VHF, Chan JYW, Vardhanabhuti V, Kwong DLW, Leung TW, Chan SY, Tong CC, Xu ZY, Shen L, Lee AWM.

Clin Oncol (R Coll Radiol). 2019 Aug;31(8):549-559. doi: 10.1016/j.clon.2019.05.023.


Indirect Chronic Effects of an Oleuropein-Rich Olive Leaf Extract on Sucrase-Isomaltase In Vitro and In Vivo.

Pyner A, Chan SY, Tumova S, Kerimi A, Williamson G.

Nutrients. 2019 Jul 1;11(7). pii: E1505. doi: 10.3390/nu11071505.


Inhibition of CHK 1 (Checkpoint Kinase 1) Elicits Therapeutic Effects in Pulmonary Arterial Hypertension.

Bourgeois A, Bonnet S, Breuils-Bonnet S, Habbout K, Paradis R, Tremblay E, Lampron MC, Orcholski ME, Potus F, Bertero T, Peterlini T, Chan SY, Norris KA, Paulin R, Provencher S, Boucherat O.

Arterioscler Thromb Vasc Biol. 2019 Aug;39(8):1667-1681. doi: 10.1161/ATVBAHA.119.312537. Epub 2019 May 16.


The molecular rationale for therapeutic targeting of glutamine metabolism in pulmonary hypertension.

Bertero T, Perk D, Chan SY.

Expert Opin Ther Targets. 2019 Jun;23(6):511-524. doi: 10.1080/14728222.2019.1615438. Epub 2019 May 11. Review.


Optical coherent tomographic angiographic pattern of the deep choroidal layer and choriocapillaris after photodynamic therapy for central serous chorioretinopathy.

Chan SY, Pan CT, Wang Q, Shi XH, Jonas JB, Wei WB.

Graefes Arch Clin Exp Ophthalmol. 2019 Jul;257(7):1365-1372. doi: 10.1007/s00417-019-04318-x. Epub 2019 Apr 29.


Does an assessment aid improve Glasgow Coma Scale scoring by helicopter rescuers in Hong Kong: A randomised controlled trial.

Chan SY, Tsang CH, Woo WWK, Yeung CY, Leung LY, Lo RSL, Hung KKC, Graham CA.

Australas Emerg Care. 2018 Aug;21(3):105-110. doi: 10.1016/j.auec.2018.06.001. Epub 2018 Jun 25.


Iron status and risk factors of iron deficiency among pregnant women in Singapore: a cross-sectional study.

Loy SL, Lim LM, Chan SY, Tan PT, Chee YL, Quah PL, Chan JKY, Tan KH, Yap F, Godfrey KM, Shek LP, Chong MF, Kramer MS, Chong YS, Chi C.

BMC Public Health. 2019 Apr 11;19(1):397. doi: 10.1186/s12889-019-6736-y.


A Point Prevalence Study of Antimicrobial Use and Practice Among Nursing Homes in Singapore.

Selcuk A, Yap KZ, Wong CL, Yang JX, Yong PC, Chan SY, Teng CB.

Drugs Aging. 2019 Jun;36(6):559-570. doi: 10.1007/s40266-019-00651-2.


Agreement between capillary and venous lactate in emergency department patients: prospective observational study.

Graham CA, Leung LY, Lo RS, Lee KH, Yeung CY, Chan SY, Cattermole GN, Hung KK.

BMJ Open. 2019 Apr 3;9(4):e026109. doi: 10.1136/bmjopen-2018-026109.


Metabolism of 13C-Labeled Fatty Acids in Term Human Placental Explants by Liquid Chromatography-Mass Spectrometry.

Watkins OC, Islam MO, Selvam P, Pillai RA, Cazenave-Gassiot A, Bendt AK, Karnani N, Godfrey KM, Lewis RM, Wenk MR, Chan SY.

Endocrinology. 2019 Jun 1;160(6):1394-1408. doi: 10.1210/en.2018-01020.


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