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Items: 1 to 50 of 731

1.

Revisiting oral fluoropyrimidine with cetuximab in metastatic colorectal cancer: Real-world data in Chinese population.

Lam KO, Fu MC, Lau KS, Lam KM, Choi CW, Chiu WH, Yuen CM, Kwok LH, Tam FK, Chan WL, Chan SY, Ho PY, Leung TW, Lee HF.

World J Gastrointest Oncol. 2019 Nov 15;11(11):1031-1042. doi: 10.4251/wjgo.v11.i11.1031.

2.

A network-based approach to uncover microRNA-mediated disease comorbidities and potential pathobiological implications.

Jin S, Zeng X, Fang J, Lin J, Chan SY, Erzurum SC, Cheng F.

NPJ Syst Biol Appl. 2019 Nov 13;5:41. doi: 10.1038/s41540-019-0115-2. eCollection 2019.

3.

Dopamine and cAMP-regulated phosphoprotein 32 kDa (DARPP-32) and survival in breast cancer: a retrospective analysis of protein and mRNA expression.

Kotecha S, Lebot MN, Sukkarn B, Ball G, Moseley PM, Chan SY, Green AR, Rakha E, Ellis IO, Martin SG, Storr SJ.

Sci Rep. 2019 Nov 18;9(1):16987. doi: 10.1038/s41598-019-53529-z.

4.

Formulation strategy of nitrofurantoin: co-crystal or solid dispersion?

Teoh XY, Bt Mahyuddin FN, Ahmad W, Chan SY.

Pharm Dev Technol. 2019 Nov 25:1-7. doi: 10.1080/10837450.2019.1689401. [Epub ahead of print]

PMID:
31690150
5.

PARP1 blockade is synthetically lethal in XRCC1 deficient sporadic epithelial ovarian cancers.

Ali R, Alabdullah M, Alblihy A, Miligy I, Mesquita KA, Chan SY, Moseley P, Rakha EA, Madhusudan S.

Cancer Lett. 2019 Oct 24. pii: S0304-3835(19)30538-5. doi: 10.1016/j.canlet.2019.10.035. [Epub ahead of print]

PMID:
31669203
6.

Were infections in migrants associated with the resurgence of measles epidemic during 2013-2014 in southern China? A retrospective data analysis.

Chong KC, Hu P, Chan SY, Liang W, Mohammad KN, Sun R, Wang MH, Zee BCY, Shi D, Zheng H.

Int J Infect Dis. 2019 Oct 18;90:77-83. doi: 10.1016/j.ijid.2019.10.014. [Epub ahead of print]

7.

Levothyroxine to increase live births in euthyroid women with thyroid antibodies trying to conceive: the TABLET RCT.

Dhillon-Smith RK, Middleton LJ, Sunner KK, Cheed V, Baker K, Farrell-Carver S, Bender-Atik R, Agrawal R, Bhatia K, Edi-Osagie E, Ghobara T, Gupta P, Jurkovic D, Khalaf Y, MacLean M, McCabe C, Mulbagal K, Nunes N, Overton C, Quenby S, Rai R, Raine-Fenning N, Robinson L, Ross J, Sizer A, Small R, Tan A, Underwood M, Kilby MD, Boelaert K, Daniels J, Thangaratinam S, Chan SY, Coomarasamy A.

Southampton (UK): NIHR Journals Library; 2019 Oct.

8.

Smart Phone APP to Restore Optimal Weight (SPAROW): protocol for a randomised controlled trial for women with recent gestational diabetes.

Lim K, Chi C, Chan SY, Lim SL, Ang SM, Yoong JS, Tsai C, Wong SR, Yew TW, Tai ES, Yong EL.

BMC Public Health. 2019 Oct 15;19(1):1287. doi: 10.1186/s12889-019-7691-3.

9.

Lrrc7 mutant mice model developmental emotional dysregulation that can be alleviated by mGluR5 allosteric modulation.

Chong CH, Li Q, Mak PHS, Ng CCP, Leung EHW, Tan VH, Chan AKW, McAlonan G, Chan SY.

Transl Psychiatry. 2019 Oct 3;9(1):244. doi: 10.1038/s41398-019-0580-9.

10.

Activation of The Metabolic Master Regulator PPARγ - A Potential PIOneering Therapy for Pulmonary Arterial Hypertension.

Hansmann G, Calvier L, Risbano MG, Chan SY.

Am J Respir Cell Mol Biol. 2019 Oct 2. doi: 10.1165/rcmb.2019-0226PS. [Epub ahead of print]

PMID:
31577451
11.

Negative plasma Epstein-Barr virus DNA nasopharyngeal carcinoma in an endemic region and its influence on liquid biopsy screening programmes.

Nicholls JM, Lee VH, Chan SK, Tsang KC, Choi CW, Kwong DL, Lam KO, Chan SY, Tong CC, So TH, Leung TW, Luk MY, Khong PL, Lee AW.

Br J Cancer. 2019 Oct;121(8):690-698. doi: 10.1038/s41416-019-0575-6. Epub 2019 Sep 17.

PMID:
31527689
12.

NFU1, Iron-Sulfur Biogenesis, and Pulmonary Arterial Hypertension: A (Metabolic) Shift in our Thinking.

Culley MK, Perk D, Chan SY.

Am J Respir Cell Mol Biol. 2019 Sep 17. doi: 10.1165/rcmb.2019-0309ED. [Epub ahead of print] No abstract available.

PMID:
31526282
13.

A dual-action chitosan-based nanogel system of triclosan and flurbiprofen for localised treatment of periodontitis.

Aminu N, Chan SY, Yam MF, Toh SM.

Int J Pharm. 2019 Oct 30;570:118659. doi: 10.1016/j.ijpharm.2019.118659. Epub 2019 Sep 4.

PMID:
31493495
14.

Cross-Cultural Adaptation and Validation of the Hong Kong Version of the Knee Injury and Osteoarthritis Outcome Score (HK-KOOS) for Patients with Knee Osteoarthritis.

Cheng ASK, Chan KC, Chan SY, Fan MK, Fung MK, Lee OY, Kwok CTT, Wong JKK.

Occup Ther Int. 2019 Aug 14;2019:8270637. doi: 10.1155/2019/8270637. eCollection 2019.

15.

An enzymatic assay for quantification of inositol in human term placental tissue.

Islam MO, Selvam P, Appukuttan Pillai R, Watkins OC, Chan SY.

Anal Biochem. 2019 Dec 1;586:113409. doi: 10.1016/j.ab.2019.113409. Epub 2019 Aug 27.

PMID:
31469978
16.

Ocular Axial Length and Diabetic Retinopathy: The Kailuan Eye Study.

Wang Q, Wang YX, Wu SL, Chen SH, Yan YN, Yang MC, Yang JY, Zhou WJ, Chan SY, Zhang XH, Yang X, Lei YH, Qin SQ, Chen MX, Jonas JB, Wei WB.

Invest Ophthalmol Vis Sci. 2019 Aug 1;60(10):3689-3695. doi: 10.1167/iovs.19-27531.

PMID:
31469896
17.

Motivations and Barriers Associated With Physician Volunteerism for an International Telemedicine Organization.

Kim EJ, Fox S, Moretti ME, Turner M, Girard TD, Chan SY.

Front Public Health. 2019 Aug 13;7:224. doi: 10.3389/fpubh.2019.00224. eCollection 2019.

18.

Socio-demographic and maternal predictors of adherence to 24-hour movement guidelines in Singaporean children.

Chen B, Bernard JY, Padmapriya N, Yao J, Goh C, Tan KH, Yap F, Chong YS, Shek L, Godfrey KM, Chan SY, Eriksson JG, Müller-Riemenschneider F.

Int J Behav Nutr Phys Act. 2019 Aug 22;16(1):70. doi: 10.1186/s12966-019-0834-1.

19.

Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor β (RARβ).

Liu HJ, Lam HC, Baglini CV, Nijmeh J, Cottrill AA, Chan SY, Henske EP.

Oncogene. 2019 Dec;38(49):7367-7383. doi: 10.1038/s41388-019-0957-5. Epub 2019 Aug 16.

PMID:
31420607
20.

Television viewing and child cognition in a longitudinal birth cohort in Singapore: the role of maternal factors.

Aishworiya R, Cai S, Chen HY, Phua DY, Broekman BFP, Daniel LM, Chong YS, Shek LP, Yap F, Chan SY, Meaney MJ, Law EC.

BMC Pediatr. 2019 Aug 16;19(1):286. doi: 10.1186/s12887-019-1651-z.

21.

Development of a prediction model for breast cancer based on the national cancer registry in Taiwan.

Huang CC, Chan SY, Lee WC, Chiang CJ, Lu TP, Cheng SH.

Breast Cancer Res. 2019 Aug 13;21(1):92. doi: 10.1186/s13058-019-1172-6.

22.

ERCC1 Is a Predictor of Anthracycline Resistance and Taxane Sensitivity in Early Stage or Locally Advanced Breast Cancers.

Abdel-Fatah TMA, Ali R, Sadiq M, Moseley PM, Mesquita KA, Ball G, Green AR, Rakha EA, Chan SYT, Madhusudan S.

Cancers (Basel). 2019 Aug 10;11(8). pii: E1149. doi: 10.3390/cancers11081149.

23.

Myo-inositol alters 13C-labeled fatty acid metabolism in human placental explants.

Watkins OC, Islam MO, Selvam P, Pillai RA, Cazenave-Gassiot A, Bendt AK, Karnani N, Godfrey KM, Lewis RM, Wenk MR, Chan SY.

J Endocrinol. 2019 Aug 1. pii: JOE-19-0267.R1. doi: 10.1530/JOE-19-0267. [Epub ahead of print]

PMID:
31404911
24.

Advancing Care for Head and Neck Cancers in a Multidisciplinary Tumour Board in the East.

Lee VHF, Chan JYW, Vardhanabhuti V, Kwong DLW, Leung TW, Chan SY, Tong CC, Xu ZY, Shen L, Lee AWM.

Clin Oncol (R Coll Radiol). 2019 Aug;31(8):549-559. doi: 10.1016/j.clon.2019.05.023.

PMID:
31279432
25.

Indirect Chronic Effects of an Oleuropein-Rich Olive Leaf Extract on Sucrase-Isomaltase In Vitro and In Vivo.

Pyner A, Chan SY, Tumova S, Kerimi A, Williamson G.

Nutrients. 2019 Jul 1;11(7). pii: E1505. doi: 10.3390/nu11071505.

26.

Inhibition of CHK 1 (Checkpoint Kinase 1) Elicits Therapeutic Effects in Pulmonary Arterial Hypertension.

Bourgeois A, Bonnet S, Breuils-Bonnet S, Habbout K, Paradis R, Tremblay E, Lampron MC, Orcholski ME, Potus F, Bertero T, Peterlini T, Chan SY, Norris KA, Paulin R, Provencher S, Boucherat O.

Arterioscler Thromb Vasc Biol. 2019 Aug;39(8):1667-1681. doi: 10.1161/ATVBAHA.119.312537. Epub 2019 May 16.

27.

The molecular rationale for therapeutic targeting of glutamine metabolism in pulmonary hypertension.

Bertero T, Perk D, Chan SY.

Expert Opin Ther Targets. 2019 Jun;23(6):511-524. doi: 10.1080/14728222.2019.1615438. Epub 2019 May 11.

PMID:
31055988
28.

Optical coherent tomographic angiographic pattern of the deep choroidal layer and choriocapillaris after photodynamic therapy for central serous chorioretinopathy.

Chan SY, Pan CT, Wang Q, Shi XH, Jonas JB, Wei WB.

Graefes Arch Clin Exp Ophthalmol. 2019 Jul;257(7):1365-1372. doi: 10.1007/s00417-019-04318-x. Epub 2019 Apr 29.

PMID:
31037490
29.

Does an assessment aid improve Glasgow Coma Scale scoring by helicopter rescuers in Hong Kong: A randomised controlled trial.

Chan SY, Tsang CH, Woo WWK, Yeung CY, Leung LY, Lo RSL, Hung KKC, Graham CA.

Australas Emerg Care. 2018 Aug;21(3):105-110. doi: 10.1016/j.auec.2018.06.001. Epub 2018 Jun 25.

PMID:
30998881
30.

Iron status and risk factors of iron deficiency among pregnant women in Singapore: a cross-sectional study.

Loy SL, Lim LM, Chan SY, Tan PT, Chee YL, Quah PL, Chan JKY, Tan KH, Yap F, Godfrey KM, Shek LP, Chong MF, Kramer MS, Chong YS, Chi C.

BMC Public Health. 2019 Apr 11;19(1):397. doi: 10.1186/s12889-019-6736-y.

31.

A Point Prevalence Study of Antimicrobial Use and Practice Among Nursing Homes in Singapore.

Selcuk A, Yap KZ, Wong CL, Yang JX, Yong PC, Chan SY, Teng CB.

Drugs Aging. 2019 Jun;36(6):559-570. doi: 10.1007/s40266-019-00651-2.

PMID:
30972716
32.

Agreement between capillary and venous lactate in emergency department patients: prospective observational study.

Graham CA, Leung LY, Lo RS, Lee KH, Yeung CY, Chan SY, Cattermole GN, Hung KK.

BMJ Open. 2019 Apr 3;9(4):e026109. doi: 10.1136/bmjopen-2018-026109.

33.

Metabolism of 13C-Labeled Fatty Acids in Term Human Placental Explants by Liquid Chromatography-Mass Spectrometry.

Watkins OC, Islam MO, Selvam P, Pillai RA, Cazenave-Gassiot A, Bendt AK, Karnani N, Godfrey KM, Lewis RM, Wenk MR, Chan SY.

Endocrinology. 2019 Jun 1;160(6):1394-1408. doi: 10.1210/en.2018-01020.

PMID:
30920585
34.

Spontaneous cutaneous adverse drug reaction reports-An analysis of a 10-year dataset in Singapore.

Wong SX, Tham MY, Goh CL, Cheong HH, Chan SY.

Pharmacol Res Perspect. 2019 Mar 13;7(2):e00469. doi: 10.1002/prp2.469. eCollection 2019 Apr.

35.

Localization of Corneal Neovascularization Using Optical Coherence Tomography Angiography.

Chan SY, Pan CT, Feng Y.

Cornea. 2019 Jul;38(7):888-895. doi: 10.1097/ICO.0000000000001931.

PMID:
30908339
36.

Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception.

Dhillon-Smith RK, Middleton LJ, Sunner KK, Cheed V, Baker K, Farrell-Carver S, Bender-Atik R, Agrawal R, Bhatia K, Edi-Osagie E, Ghobara T, Gupta P, Jurkovic D, Khalaf Y, MacLean M, McCabe C, Mulbagal K, Nunes N, Overton C, Quenby S, Rai R, Raine-Fenning N, Robinson L, Ross J, Sizer A, Small R, Tan A, Underwood M, Kilby MD, Boelaert K, Daniels J, Thangaratinam S, Chan SY, Coomarasamy A.

N Engl J Med. 2019 Apr 4;380(14):1316-1325. doi: 10.1056/NEJMoa1812537. Epub 2019 Mar 23.

PMID:
30907987
37.

Rice starch thin films as a potential buccal delivery system: Effect of plasticiser and drug loading on drug release profile.

Chan SY, Goh CF, Lau JY, Tiew YC, Balakrishnan T.

Int J Pharm. 2019 May 1;562:203-211. doi: 10.1016/j.ijpharm.2019.03.044. Epub 2019 Mar 20.

PMID:
30904726
38.

Associations of physical activity levels and screen time with oral glucose tolerance test profiles in Singaporean women of reproductive age actively trying to conceive: the S-PRESTO study.

Bernard JY, Ng S, Natarajan P, Loy SL, Aris IM, Tint MT, Chong YS, Shek L, Chan J, Godfrey KM, Khoo CM, Leow MK, Müller-Riemenschneider F, Chan SY.

Diabet Med. 2019 Jul;36(7):888-897. doi: 10.1111/dme.13948. Epub 2019 Apr 7.

PMID:
30888073
39.

Real-world treatment patterns and outcomes in refractory metastatic colorectal cancer.

Chiang CL, Choi HC, Lam KO, Chan BY, Lee SF, Yeung SY, Lau KS, Chan SY, Choy TS, Yuen KK.

Asia Pac J Clin Oncol. 2019 Mar;15 Suppl 2:5-13. doi: 10.1111/ajco.13114. Epub 2019 Mar 19.

PMID:
30887726
40.

Distinct plasma gradients of microRNA-204 in the pulmonary circulation of patients suffering from WHO Groups I and II pulmonary hypertension.

Estephan LE, Genuardi MV, Kosanovich CM, Risbano MG, Zhang Y, Petro N, Watson A, Al Aaraj Y, Sembrat JC, Rojas M, Goncharov DA, Simon MA, Goncharova EA, Vaidya A, Smith A, Mazurek J, Han Y, Chan SY.

Pulm Circ. 2019 Apr-Jun;9(2):2045894019840646. doi: 10.1177/2045894019840646.

41.

Structural instability of lamin A tail domain modulates its assembly and higher order function in Emery-Dreifuss muscular dystrophy.

Mio M, Sugiki T, Matsuda C, Mitsuhashi H, Kojima C, Chan SY, Hayashi YK, Mio K.

Biochem Biophys Res Commun. 2019 Apr 23;512(1):22-28. doi: 10.1016/j.bbrc.2019.02.138. Epub 2019 Mar 7.

PMID:
30853177
42.

Phonon confinement and size effect in Raman spectra of ZnO nanoparticles.

Korepanov VI, Chan SY, Hsu HC, Hamaguchi HO.

Heliyon. 2019 Feb 19;5(2):e01222. doi: 10.1016/j.heliyon.2019.e01222. eCollection 2019 Feb.

43.

SHON expression predicts response and relapse risk of breast cancer patients after anthracycline-based combination chemotherapy or tamoxifen treatment.

Abdel-Fatah TMA, Broom RJ, Lu J, Moseley PM, Huang B, Li L, Liu S, Chen L, Ma RZ, Cao W, Wang X, Li Y, Perry JK, Aleskandarany M, Nolan CC, Rakha EA, Lobie PE, Chan SYT, Ellis IO, Hwang LA, Lane DP, Green AR, Liu DX.

Br J Cancer. 2019 Apr;120(7):728-745. doi: 10.1038/s41416-019-0405-x. Epub 2019 Feb 28.

PMID:
30816325
44.

Nutrients or nursing? Understanding how breast milk feeding affects child cognition.

Pang WW, Tan PT, Cai S, Fok D, Chua MC, Lim SB, Shek LP, Chan SY, Tan KH, Yap F, Gluckman PD, Godfrey KM, Meaney MJ, Broekman BFP, Kramer MS, Chong YS, Rifkin-Graboi A.

Eur J Nutr. 2019 Feb 26. doi: 10.1007/s00394-019-01929-2. [Epub ahead of print]

PMID:
30809702
45.

ERCC1-XPF deficiency is a predictor of olaparib induced synthetic lethality and platinum sensitivity in epithelial ovarian cancers.

Mesquita KA, Alabdullah M, Griffin M, Toss MS, Fatah TMAA, Alblihy A, Moseley P, Chan SYT, Rakha EA, Madhusudan S.

Gynecol Oncol. 2019 May;153(2):416-424. doi: 10.1016/j.ygyno.2019.02.014. Epub 2019 Feb 21.

PMID:
30797591
46.

The Search for Disease-Modifying Therapies in Pulmonary Hypertension.

Woodcock CC, Chan SY.

J Cardiovasc Pharmacol Ther. 2019 Jul;24(4):334-354. doi: 10.1177/1074248419829172. Epub 2019 Feb 17.

47.

BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.

Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, Wendell SG, Mullett SJ, Sembrat J, Rojas M, Khan OF, Dahlman JE, Sugahara M, Kagiyama N, Satoh T, Zhang M, Feng N, Gorcsan J 3rd, Vargas SO, Haley KJ, Kumar R, Graham BB, Langer R, Anderson DG, Wang B, Shiva S, Bertero T, Chan SY.

Circulation. 2019 May 7;139(19):2238-2255. doi: 10.1161/CIRCULATIONAHA.118.035889.

PMID:
30759996
48.

Effects of herbal medicine for xerostomia in head and neck cancer patients: an observational study in a tertiary cancer hospital.

Lim RJ, Nik Nabil WN, Chan SY, Wong YF, Han LX, Gong JY, Ho KL, Shew YS, Xu L.

Support Care Cancer. 2019 Sep;27(9):3491-3498. doi: 10.1007/s00520-019-4646-2. Epub 2019 Jan 24.

PMID:
30675667
49.

Association of Elective and Emergency Cesarean Delivery With Early Childhood Overweight at 12 Months of Age.

Cai M, Loy SL, Tan KH, Godfrey KM, Gluckman PD, Chong YS, Shek LP, Cheung YB, Lek N, Lee YS, Chan SY, Chan JKY, Yap F, Ang SB.

JAMA Netw Open. 2018 Nov 2;1(7):e185025. doi: 10.1001/jamanetworkopen.2018.5025.

50.

qSOFA is a Poor Predictor of Short-Term Mortality in All Patients: A Systematic Review of 410,000 Patients.

Lo RSL, Leung LY, Brabrand M, Yeung CY, Chan SY, Lam CCY, Hung KKC, Graham CA.

J Clin Med. 2019 Jan 8;8(1). pii: E61. doi: 10.3390/jcm8010061. Review.

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