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A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo.

Covés-Datson EM, King SR, Legendre M, Gupta A, Chan SM, Gitlin E, Kulkarni VV, Pantaleón García J, Smee DF, Lipka E, Evans SE, Tarbet EB, Ono A, Markovitz DM.

Proc Natl Acad Sci U S A. 2020 Jan 13. pii: 201915152. doi: 10.1073/pnas.1915152117. [Epub ahead of print]


Molecular characterisation of an avian influenza (H5N8) outbreak in backyard flocks in Al Ahsa, Eastern Saudi Arabia, 2017-2018.

Hemida MG, Chu D, Abdelaziz A, Alnaeem A, Chan SMS, Peiris M.

Vet Rec Open. 2019 Dec 1;6(1):e000362. doi: 10.1136/vetreco-2019-000362. eCollection 2019.


Optimal effect-site concentration of propofol for tracheal suctioning during emergence from ophthalmic surgery.

Hung NK, Lee MS, Lai HC, Huang YH, Lin BF, Chan SM, Wu ZF.

Medicine (Baltimore). 2020 Jan;99(1):e18669. doi: 10.1097/MD.0000000000018669.


Propofol-based total intravenous anesthesia is associated with better survival than desflurane anesthesia in intrahepatic cholangiocarcinoma surgery.

Lai HC, Lee MS, Lin KT, Chan SM, Chen JY, Lin YT, Wu ZF.

Medicine (Baltimore). 2019 Dec;98(51):e18472. doi: 10.1097/MD.0000000000018472.


Endoscopic management of Wirsungocele with recurrent acute pancreatitis.

Cheung RLY, Chan SM, Yip HC, Teoh AYB.

Endoscopy. 2019 Dec 2. doi: 10.1055/a-1046-1940. [Epub ahead of print] No abstract available.


Pneumococcal Pneumonia Resembling Acute Myocardial Infarction in an Adolescent Male.

Chiong YK, Tan I, Lim TC, Thong WY, Chan MY, Chan SM.

Pediatr Infect Dis J. 2020 Jan;39(1):81-84. doi: 10.1097/INF.0000000000002527.


Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response.

Sharon D, Cathelin S, Mirali S, Di Trani JM, Yanofsky DJ, Keon KA, Rubinstein JL, Schimmer AD, Ketela T, Chan SM.

Sci Transl Med. 2019 Oct 30;11(516). pii: eaax2863. doi: 10.1126/scitranslmed.aax2863.


Assessment of Sarcopenia Among Community-Dwelling At-Risk Frail Adults Aged 65 Years and Older Who Received Multidomain Lifestyle Interventions: A Secondary Analysis of a Randomized Clinical Trial.

Lu Y, Niti M, Yap KB, Tan CTY, Zin Nyunt MS, Feng L, Tan BY, Chan G, Khoo SA, Chan SM, Yap P, Larbi A, Ng TP.

JAMA Netw Open. 2019 Oct 2;2(10):e1913346. doi: 10.1001/jamanetworkopen.2019.13346.


New Service Model for Common Mental Disorders in Hong Kong: a Retrospective Outcome Study.

Lee WK, Lo A, Chong G, Chang SYS, Lu V, Yip PLI, Liu CMK, Leung M, Chung CM, Wong KY, Yeung YYE, Chan SMA, Ngai YS, Wong PS, Lo TL.

East Asian Arch Psychiatry. 2019 Sep;29(3):75-80. doi: 10.12809/eaap1822.


Cigarette Smoking Exacerbates Skeletal Muscle Injury Without Compromising its Regenerative Capacity.

Chan SM, Cerni C, Passey S, Seow HJ, Bernardo I, van der Poel C, Dobric A, Brassington K, Selemidis S, Bozinovski S, Vlahos R.

Am J Respir Cell Mol Biol. 2019 Aug 28. doi: 10.1165/rcmb.2019-0106OC. [Epub ahead of print]


Application of CRISPR-Cas9 Screening Technologies to Study Mitochondrial Biology in Healthy and Disease States.

Sharon D, Chan SM.

Adv Exp Med Biol. 2019;1158:269-277. doi: 10.1007/978-981-13-8367-0_15. Review.


Impact of preleukemic mutations and their persistence on hematologic recovery after induction chemotherapy for AML.

Murphy T, Zou J, Daher-Reyes GS, Arruda A, Gupta V, McNamara CJ, Minden MD, Schimmer AD, Sibai H, Yee KWL, Korulla M, Stockley T, Kamel-Reid S, Maze D, Tierens A, Bratman SV, Schuh AC, Chan SM.

Blood Adv. 2019 Aug 13;3(15):2307-2311. doi: 10.1182/bloodadvances.2019000306. No abstract available.


Outcomes of an international multicenter registry on EUS-guided gallbladder drainage in patients at high risk for cholecystectomy.

Teoh AY, Perez-Miranda M, Kunda R, Lee SS, Irani S, Yeaton P, Sun S, Baron TH, Moon JH, Holt B, Khor CJL, Rerknimitr R, Bapaye A, Chan SM, Choi HJ, James TW, Kongkam P, Lee YN, Parekh P, Ridtitid W, Serna-Higuera C, Tan DMY, Torres-Yuste R.

Endosc Int Open. 2019 Aug;7(8):E964-E973. doi: 10.1055/a-0915-2098. Epub 2019 Jul 24.


Prospective multicenter international study on the outcomes of a newly developed self-approximating lumen-apposing metallic stent for drainage of pancreatic fluid collections and endoscopic necrosectomy.

Teoh AYB, Bapaye A, Lakhtakia S, Ratanachu T, Reknimitr R, Chan SM, Choi HJ, Gadhikar HP, Kongkam P, Korrapati SK, Lee YN, Medarapalem J, Ridtitid W, Moon JH.

Dig Endosc. 2019 Jul 25. doi: 10.1111/den.13494. [Epub ahead of print]


Propofol-based total intravenous anaesthesia is associated with better survival than desflurane anaesthesia in hepatectomy for hepatocellular carcinoma: a retrospective cohort study.

Lai HC, Lee MS, Lin C, Lin KT, Huang YH, Wong CS, Chan SM, Wu ZF.

Br J Anaesth. 2019 Aug;123(2):151-160. doi: 10.1016/j.bja.2019.04.057. Epub 2019 Jun 3.


Positive relationship between consumption of specific fish type and n-3 PUFA in milk of Hong Kong lactating mothers.

Wong VW, Ng YF, Chan SM, Su YX, Kwok KW, Chan HM, Cheung CL, Lee HW, Pak WY, Li SY, Wong MS.

Br J Nutr. 2019 Jun;121(12):1431-1440. doi: 10.1017/S0007114519000801. Epub 2019 Apr 12.


Optimizing survival outcomes with post-remission therapy in acute myeloid leukemia.

Medeiros BC, Chan SM, Daver NG, Jonas BA, Pollyea DA.

Am J Hematol. 2019 Jul;94(7):803-811. doi: 10.1002/ajh.25484. Epub 2019 May 1. Review.


Intracranial Hypotension and Cerebrospinal Fluid Leak.

Chan SM, Chodakiewitz YG, Maya MM, Schievink WI, Moser FG.

Neuroimaging Clin N Am. 2019 May;29(2):213-226. doi: 10.1016/j.nic.2019.01.002. Epub 2019 Feb 21. Review.


Effects of intraoperative propofol-based total intravenous anesthesia on postoperative pain in spine surgery: Comparison with desflurane anesthesia - a randomised trial.

Lin WL, Lee MS, Wong CS, Chan SM, Lai HC, Wu ZF, Lu CH.

Medicine (Baltimore). 2019 Mar;98(13):e15074. doi: 10.1097/MD.0000000000015074.


Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic strategies.

Chan SMH, Selemidis S, Bozinovski S, Vlahos R.

Pharmacol Ther. 2019 Jun;198:160-188. doi: 10.1016/j.pharmthera.2019.02.013. Epub 2019 Feb 26.


The HERV-K accessory protein Np9 controls viability and migration of teratocarcinoma cells.

Chan SM, Sapir T, Park SS, Rual JF, Contreras-Galindo R, Reiner O, Markovitz DM.

PLoS One. 2019 Feb 28;14(2):e0212970. doi: 10.1371/journal.pone.0212970. eCollection 2019.


The Association between Mushroom Consumption and Mild Cognitive Impairment: A Community-Based Cross-Sectional Study in Singapore.

Feng L, Cheah IK, Ng MM, Li J, Chan SM, Lim SL, Mahendran R, Kua EH, Halliwell B.

J Alzheimers Dis. 2019;68(1):197-203. doi: 10.3233/JAD-180959.


The successful application of high flow nasal cannula for awake craniotomy.

Lin YC, Liu YT, Wu ZF, Chan SM.

J Clin Anesth. 2019 Aug;55:140-141. doi: 10.1016/j.jclinane.2019.01.012. Epub 2019 Jan 15. No abstract available.


The Making of a Leukemic Stem Cell: A Novel Role for IKZF2 in AML Stemness and Differentiation.

Chan SM.

Cell Stem Cell. 2019 Jan 3;24(1):5-6. doi: 10.1016/j.stem.2018.12.007.


Per oral endoscopic tumor (POET) resection for treatment of upper gastrointestinal subepithelial tumors.

Chiu PWY, Yip HC, Teoh AYB, Wong VWY, Chan SM, Wong SKH, Ng EKW.

Surg Endosc. 2019 Apr;33(4):1326-1333. doi: 10.1007/s00464-018-06627-4. Epub 2019 Jan 2.


How I do it: Flexible 3-D endoscope for endoscopic submucosal dissection.

Chiu PWY, Yip HC, Xia XF, Chan SM, Ng EKW, Lau JYW.

Dig Endosc. 2019 May;31(3):323-328. doi: 10.1111/den.13315. Epub 2019 Mar 21.


Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia.

Bhatt DL, Steg PG, Miller M, Brinton EA, Jacobson TA, Ketchum SB, Doyle RT Jr, Juliano RA, Jiao L, Granowitz C, Tardif JC, Ballantyne CM; REDUCE-IT Investigators.

N Engl J Med. 2019 Jan 3;380(1):11-22. doi: 10.1056/NEJMoa1812792. Epub 2018 Nov 10.


Idiopathic granulomatous mastitis: a 10-year study from a multicentre clinical database.

Co M, Cheng VCC, Wei J, Wong SCY, Chan SMS, Shek T, Kwong A.

Pathology. 2018 Dec;50(7):742-747. doi: 10.1016/j.pathol.2018.08.010. Epub 2018 Oct 30.


Ethnic disparities in relationships of obesity indices with telomere length in Asians with type 2 diabetes.

Gurung RL, M Y, Liu S, Liu JJ, Chan SM, Moh MC, Ang K, Tang WE, Sum CF, Tavintharan S, Lim SC; SMART2D Study.

J Diabetes. 2019 May;11(5):386-393. doi: 10.1111/1753-0407.12864. Epub 2018 Nov 8.


Comparing monovalent and combination hepatitis B vaccine outcomes in children delivered by mothers with chronic hepatitis B.

Lee LY, Chan SM, Ong C, M Aw M, Wong F, Saw S, Lee GH, Thoon KC, Phua KB.

J Paediatr Child Health. 2019 Mar;55(3):327-332. doi: 10.1111/jpc.14194. Epub 2018 Aug 30.


Baicalein attenuates neuropathic pain and improves sciatic nerve function recovery in rats with partial sciatic nerve transection.

Lai HC, Lu CH, Wong CS, Lin BF, Chan SM, Kuo CY, Wu ZF.

J Chin Med Assoc. 2018 Nov;81(11):955-963. doi: 10.1016/j.jcma.2018.03.014. Epub 2018 Aug 20.


Lifestyle intervention in obese Chinese adolescents with non-alcoholic fatty liver disease: a randomised controlled study.

Chan DF, Nelson EA, Li AM, Woo J, Sea MM, Chan RS, Chu WC, Chan M, So HK.

Hong Kong Med J. 2018 Aug;24 Suppl 4(4):12-15. No abstract available.


A diagnosis of Stevens-Johnson Syndrome (SJS) in a patient presenting with superficial keratitis.

Chan F, Benson MD, Plemel DJA, Mahmood MN, Chan SM.

Am J Ophthalmol Case Rep. 2018 Jun 19;11:167-169. doi: 10.1016/j.ajoc.2018.06.004. eCollection 2018 Sep.


Vitamin D deficiency among healthy infants in Hong Kong: a pilot study.

Chan KC, Tam WH, Chan MH, Chan RS, Li AM.

Hong Kong Med J. 2018 Jun;24 Suppl 3(3):32-35. No abstract available.


The Relationship Between Postoperative Pneumonia and Endotracheal Suctioning Under General Anesthesia in Ophthalmic Surgery: A Retrospective Study.

Lai HC, Pao SI, Huang YS, Chan SM, Lin BF, Wu ZF.

Asian J Anesthesiol. 2018 Mar;56(1):33-38. doi: 10.6859/aja.201803_56(1).0004.


AML refractory to primary induction with Ida-FLAG has a poor clinical outcome.

Kavanagh S, Heath E, Hurren R, Gronda M, Barghout SH, Liyanage SU, Siriwardena TP, Claudio J, Zhang T, Sukhai M, Stockley TL, Kamel-Reid S, Rostom A, Lutynski A, Khalaf D, Rydlewski A, Chan SM, Gupta V, Maze D, Sibai H, Schuh AC, Yee K, Minden MD, Schimmer AD.

Leuk Res. 2018 May;68:22-28. doi: 10.1016/j.leukres.2018.02.012. Epub 2018 Feb 20.


The inositol-requiring enzyme 1 (IRE1α) RNAse inhibitor, 4µ8C, is also a potent cellular antioxidant.

Chan SMH, Lowe MP, Bernard A, Miller AA, Herbert TP.

Biochem J. 2018 Mar 9;475(5):923-929. doi: 10.1042/BCJ20170678.


3',4'-dihydroxyflavonol ameliorates endoplasmic reticulum stress-induced apoptosis and endothelial dysfunction in mice.

Lau YS, Mustafa MR, Choy KW, Chan SMH, Potocnik S, Herbert TP, Woodman OL.

Sci Rep. 2018 Jan 29;8(1):1818. doi: 10.1038/s41598-018-19584-8.


A "Stone in the Pond" Approach to Contact Tracing: Responding to a Large-Scale, Nosocomial Tuberculosis Exposure in a Moderate TB-Burden Setting.

Bagdasarian N, Chan HC, Ang S, Isa MS, Chan SM, Fisher DA.

Infect Control Hosp Epidemiol. 2017 Dec;38(12):1509-1511. doi: 10.1017/ice.2017.228. Epub 2017 Nov 28.


Recurrent Mycobacterium fortuitum insulin injection site abscesses.

Han VX, Loke KY, Chan SM.

J Paediatr Child Health. 2018 Mar;54(3):316-318. doi: 10.1111/jpc.13788. Epub 2017 Nov 23. No abstract available.


Moderate iodine deficiency among pregnant women in Hong Kong: revisit the problem after two decades.

Tam WH, Chan RS, Chan MH, Yuen LY, Li L, Sea MM, Woo J.

Hong Kong Med J. 2017 Dec;23(6):586-93. doi: 10.12809/hkmj176841. Epub 2017 Nov 10.


Cognitive Effects of Multi-Domain Interventions Among Pre-Frail and Frail Community-Living Older Persons: Randomized Controlled Trial.

Ng TP, Ling LHA, Feng L, Nyunt MSZ, Feng L, Niti M, Tan BY, Chan G, Khoo SA, Chan SM, Yap P, Yap KB.

J Gerontol A Biol Sci Med Sci. 2018 May 9;73(6):806-812. doi: 10.1093/gerona/glx207.


Multi-Domains Lifestyle Interventions Reduces Depressive Symptoms among Frail and Pre-Frail Older Persons: Randomized Controlled Trial.

Ng TP, Nyunt MSZ, Feng L, Feng L, Niti M, Tan BY, Chan G, Khoo SA, Chan SM, Yap P, Yap KB.

J Nutr Health Aging. 2017;21(8):918-926. doi: 10.1007/s12603-016-0867-y.


Patients with Primary Immunodeficiencies Are a Reservoir of Poliovirus and a Risk to Polio Eradication.

Aghamohammadi A, Abolhassani H, Kutukculer N, Wassilak SG, Pallansch MA, Kluglein S, Quinn J, Sutter RW, Wang X, Sanal O, Latysheva T, Ikinciogullari A, Bernatowska E, Tuzankina IA, Costa-Carvalho BT, Franco JL, Somech R, Karakoc-Aydiner E, Singh S, Bezrodnik L, Espinosa-Rosales FJ, Shcherbina A, Lau YL, Nonoyama S, Modell F, Modell V; JMF Centers Network Investigators and Study Collaborators, Barbouche MR, McKinlay MA.

Front Immunol. 2017 Jun 13;8:685. doi: 10.3389/fimmu.2017.00685. eCollection 2017.


Angiotensin II Causes β-Cell Dysfunction Through an ER Stress-Induced Proinflammatory Response.

Chan SMH, Lau YS, Miller AA, Ku JM, Potocnik S, Ye JM, Woodman OL, Herbert TP.

Endocrinology. 2017 Oct 1;158(10):3162-3173. doi: 10.1210/en.2016-1879.


Can we now recommend OTSC as first-line therapy in case of non-variceal upper gastrointestinal bleeding?

Chan SM, Lau JY.

Endosc Int Open. 2017 Sep;5(9):E883-E885. doi: 10.1055/s-0043-111722. Epub 2017 Sep 12. No abstract available.


A46 MERS-CoV in Arabian camels in Africa and Central Asia.

Chu DKW, Chan SMS, Perera RAPM, Miguel E, Roger F, Chevalier V, Poon LLM, Peiris M.

Virus Evol. 2017 Mar 5;3(Suppl 1). pii: vew036.045. doi: 10.1093/ve/vew036.045. eCollection 2017 Mar. No abstract available.


Levobuipivacaine-Induced Dissemination of A549 Lung Cancer Cells.

Chan SM, Lin BF, Wong CS, Chuang WT, Chou YT, Wu ZF.

Sci Rep. 2017 Aug 17;7(1):8646. doi: 10.1038/s41598-017-08885-z.

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