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Items: 45

1.

Do immune cells lead the way in subchondral bone disturbance in osteoarthritis?

Weber A, Chan PMB, Wen C.

Prog Biophys Mol Biol. 2017 Dec 22. pii: S0079-6107(17)30181-5. doi: 10.1016/j.pbiomolbio.2017.12.004. [Epub ahead of print] Review.

PMID:
29277342
2.

Is subchondral bone cyst formation in non-load-bearing region of osteoarthritic knee a vascular problem?

Chan PMB, Wen C, Yang WC, Yan C, Chiu K.

Med Hypotheses. 2017 Nov;109:80-83. doi: 10.1016/j.mehy.2017.09.027. Epub 2017 Sep 28.

PMID:
29150301
3.

Majority of flat epithelial atypia diagnosed on biopsy do not require surgical excision.

Chan PMY, Chotai N, Lai ES, Sin PY, Chen J, Lu SQ, Goh MH, Chong BK, Ho BCS, Tan EY.

Breast. 2018 Feb;37:13-17. doi: 10.1016/j.breast.2017.10.005. Epub 2017 Oct 15.

PMID:
29040892
4.

Mastectomy rates remain high in Singapore and are not associated with poorer survival after adjusting for age.

Chan PM, Choo BA, Zhang T, Seah MD, Chen JJ, Lu SQ, Tan EY.

Springerplus. 2015 Nov 10;4:685. doi: 10.1186/s40064-015-1460-2. eCollection 2015.

5.
6.

An interconnected hierarchical model of cell death regulation by the BCL-2 family.

Chen HC, Kanai M, Inoue-Yamauchi A, Tu HC, Huang Y, Ren D, Kim H, Takeda S, Reyna DE, Chan PM, Ganesan YT, Liao CP, Gavathiotis E, Hsieh JJ, Cheng EH.

Nat Cell Biol. 2015 Oct;17(10):1270-81. doi: 10.1038/ncb3236. Epub 2015 Sep 7.

7.

Extent of margin involvement, lymphovascular invasion, and extensive intraductal component predict for residual disease after wide local excision for breast cancer.

Alrahbi S, Chan PM, Ho BC, Seah MD, Chen JJ, Tan EY.

Clin Breast Cancer. 2015 Jun;15(3):219-26. doi: 10.1016/j.clbc.2014.12.004. Epub 2014 Dec 24.

PMID:
25576998
8.

Limiting the use of primary endocrine therapy in elderly women with breast cancer.

Chan SW, Chan PM, Seah MD, Chen JJ, Tan EY.

Ann Acad Med Singapore. 2014 Sep;43(9):469-72.

9.

Adopting ambulatory breast cancer surgery as the standard of care in an asian population.

Ng YY, Chan PM, Chen JJ, Seah MD, Teo C, Tan EY.

Int J Breast Cancer. 2014;2014:672743. doi: 10.1155/2014/672743. Epub 2014 Aug 12.

10.

The use of traditional Chinese medicine among breast cancer patients: implications for the clinician.

Wong KY, Tan EY, Chen JJ, Teo C, Chan PM.

Ann Acad Med Singapore. 2014 Feb;43(2):74-8.

11.

Catalytic reduction of hydrazine to ammonia by a mononuclear iron(II) complex on a tris(thiolato)phosphine platform.

Chang YH, Chan PM, Tsai YF, Lee GH, Hsu HF.

Inorg Chem. 2014 Jan 21;53(2):664-6. doi: 10.1021/ic402108w. Epub 2013 Dec 30.

PMID:
24377381
12.

Sentinel Lymph Node Biopsy Should Be Included with the Initial Surgery for High-Risk Ductal Carcinoma-In-Situ.

Tan EY, Lo ZW, Ang CH, Teo C, Seah MD, Chen JJ, Chan PM.

Int Sch Res Notices. 2014 Oct 29;2014:624185. doi: 10.1155/2014/624185. eCollection 2014.

13.

Amauroderma rugosum (Blume & T. Nees) Torrend: Nutritional Composition and Antioxidant and Potential Anti-Inflammatory Properties.

Chan PM, Kanagasabapathy G, Tan YS, Sabaratnam V, Kuppusamy UR.

Evid Based Complement Alternat Med. 2013;2013:304713. doi: 10.1155/2013/304713. Epub 2013 Nov 25.

14.

A spatio-temporal understanding of growth regulation during the salt stress response in Arabidopsis.

Geng Y, Wu R, Wee CW, Xie F, Wei X, Chan PM, Tham C, Duan L, Dinneny JR.

Plant Cell. 2013 Jun;25(6):2132-54. doi: 10.1105/tpc.113.112896. Epub 2013 Jun 28.

15.

PUMA and BIM are required for oncogene inactivation-induced apoptosis.

Bean GR, Ganesan YT, Dong Y, Takeda S, Liu H, Chan PM, Huang Y, Chodosh LA, Zambetti GP, Hsieh JJ, Cheng EH.

Sci Signal. 2013 Mar 26;6(268):ra20. doi: 10.1126/scisignal.2003483.

16.

Endodermal ABA signaling promotes lateral root quiescence during salt stress in Arabidopsis seedlings.

Duan L, Dietrich D, Ng CH, Chan PM, Bhalerao R, Bennett MJ, Dinneny JR.

Plant Cell. 2013 Jan;25(1):324-41. doi: 10.1105/tpc.112.107227. Epub 2013 Jan 22.

17.

Achieving breast cancer surgery in a single setting with intraoperative frozen section analysis of the sentinel lymph node.

Lu Q, Tan EY, Ho B, Teo C, Seah MD, Chen JJ, Chan PM.

Clin Breast Cancer. 2013 Apr;13(2):140-5. doi: 10.1016/j.clbc.2012.11.005. Epub 2012 Dec 5.

PMID:
23218472
18.

Advanced breast cancer-are we doing enough?

Pek CH, Tan EY, Chen JJ, Ho PW, Teo C, Earnest A, Chan PM.

Breast J. 2012 Nov-Dec;18(6):644-6. doi: 10.1111/tbj.12020. Epub 2012 Sep 26. No abstract available.

PMID:
23009636
19.

Surgical excision of intraductal breast papilloma diagnosed on core biopsy.

Lu Q, Tan EY, Ho B, Chen JJ, Chan PM.

ANZ J Surg. 2012 Mar;82(3):168-72. doi: 10.1111/j.1445-2197.2011.05969.x. Epub 2012 Jan 17.

PMID:
22510128
20.

PAKs in human disease.

Chan PM, Manser E.

Prog Mol Biol Transl Sci. 2012;106:171-87. doi: 10.1016/B978-0-12-396456-4.00011-0. Review.

PMID:
22340718
21.
22.

Predictors of nonsentinel nodal involvement to aid intraoperative decision making in breast cancer patients with positive sentinel lymph nodes.

Tan EY, Ho B, Chen JJ, Ho PW, Teo C, Earnest A, Chan PM.

ISRN Oncol. 2011;2011:539503. doi: 10.5402/2011/539503. Epub 2011 Aug 16.

23.
24.

Galactosylated cellulosic sponge for multi-well drug safety testing.

Nugraha B, Hong X, Mo X, Tan L, Zhang W, Chan PM, Kang CH, Wang Y, Beng LT, Sun W, Choudhury D, Robens JM, McMillian M, Silva J, Dallas S, Tan CH, Yue Z, Yu H.

Biomaterials. 2011 Oct;32(29):6982-94. doi: 10.1016/j.biomaterials.2011.05.087. Epub 2011 Jul 8.

PMID:
21741702
25.

PTB domain-directed substrate targeting in a tyrosine kinase from the unicellular choanoflagellate Monosiga brevicollis.

Prieto-Echagüe V, Chan PM, Craddock BP, Manser E, Miller WT.

PLoS One. 2011 Apr 26;6(4):e19296. doi: 10.1371/journal.pone.0019296.

26.

Differential signaling of Flt3 activating mutations in acute myeloid leukemia: a working model.

Chan PM.

Protein Cell. 2011 Feb;2(2):108-15. doi: 10.1007/s13238-011-1020-7. Epub 2011 Feb 25. Review.

27.

A robust protocol to map binding sites of the 14-3-3 interactome: Cdc25C requires phosphorylation of both S216 and S263 to bind 14-3-3.

Chan PM, Ng YW, Manser E.

Mol Cell Proteomics. 2011 Mar;10(3):M110.005157. doi: 10.1074/mcp.M110.005157. Epub 2010 Dec 28.

28.

Why an A-loop phospho-mimetic fails to activate PAK1: understanding an inaccessible kinase state by molecular dynamics simulations.

Ng YW, Raghunathan D, Chan PM, Baskaran Y, Smith DJ, Lee CH, Verma C, Manser E.

Structure. 2010 Jul 14;18(7):879-90. doi: 10.1016/j.str.2010.04.011.

29.

Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling.

Pao-Chun L, Chan PM, Chan W, Manser E.

J Biol Chem. 2009 Dec 11;284(50):34954-63. doi: 10.1074/jbc.M109.072660. Epub 2009 Oct 8.

30.

Rethinking undertreatment in elderly breast cancer patients.

Seah MD, Chan PM.

Asian J Surg. 2009 Apr;32(2):71-5. doi: 10.1016/S1015-9584(09)60013-0.

31.

PAK is regulated by PI3K, PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced p38 pathway.

Chan PM, Lim L, Manser E.

J Biol Chem. 2008 Sep 5;283(36):24949-61. doi: 10.1074/jbc.M801728200. Epub 2008 Jun 27.

32.

Differential gene expression in the striatum of mice with very low expression of the vesicular monoamine transporter type 2 gene.

Colebrooke RE, Chan PM, Lynch PJ, Mooslehner K, Emson PC.

Brain Res. 2007 Jun 4;1152:10-6. Epub 2007 Mar 15.

PMID:
17433807
33.

Teaching chronic obstructive airway disease patients using a metered-dose inhaler.

Luk HH, Chan PM, Lam FF, Lau KY, Chiu SY, Fung YL, Pang J.

Chin Med J (Engl). 2006 Oct 5;119(19):1669-72. No abstract available.

PMID:
17042981
34.

Presynaptic control of striatal dopamine neurotransmission in adult vesicular monoamine transporter 2 (VMAT2) mutant mice.

Patel J, Mooslehner KA, Chan PM, Emson PC, Stamford JA.

J Neurochem. 2003 May;85(4):898-910.

35.

Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region.

Chan PM, Ilangumaran S, La Rose J, Chakrabartty A, Rottapel R.

Mol Cell Biol. 2003 May;23(9):3067-78.

36.

Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: potential mouse model for parkinsonism.

Mooslehner KA, Chan PM, Xu W, Liu L, Smadja C, Humby T, Allen ND, Wilkinson LS, Emson PC.

Mol Cell Biol. 2001 Aug;21(16):5321-31.

37.

Embryonic XMab21l2 expression is required for gastrulation and subsequent neural development.

Lau GT, Wong OG, Chan PM, Kok KH, Wong RL, Chin KT, Lin MC, Kung HF, Chow KL.

Biochem Biophys Res Commun. 2001 Feb 9;280(5):1378-84.

PMID:
11162683
38.

Investigating the substrate specificity of the HER2/Neu tyrosine kinase using peptide libraries.

Chan PM, Nestler HP, Miller WT.

Cancer Lett. 2000 Nov 28;160(2):159-69.

PMID:
11053645
39.
40.

Splenic actinomycosis.

Chan PM, Chong SM, Ng BK, Chan ST.

J R Coll Surg Edinb. 1999 Oct;44(5):344-5.

PMID:
10550960
41.

Engineering the substrate specificity of the Abl tyrosine kinase.

Till JH, Chan PM, Miller WT.

J Biol Chem. 1999 Feb 19;274(8):4995-5003.

42.

Use of peptide libraries to determine optimal substrates of tyrosine kinases.

Chan PM, Miller WT.

Methods Mol Biol. 1998;84:75-86. No abstract available.

PMID:
9666442
43.

Amino-terminal sequence determinants for substrate recognition by platelet-derived growth factor receptor tyrosine kinase.

Chan PM, Keller PR, Connors RW, Leopold WR, Miller WT.

FEBS Lett. 1996 Sep 30;394(2):121-5.

44.

Factors influencing myeloid stem cell (CFU-C) survival after cryopreservation of human marrow and chronic granulocytic leukemia cells.

Ma DD, Johnson LA, Chan PM, Biggs JC.

Cryobiology. 1982 Feb;19(1):1-9. No abstract available.

PMID:
6950875
45.

Patterns of recurrence following curative resection alone for adenocarcinoma of the rectum and sigmoid colon.

Rao AR, Kagan AR, Chan PM, Gilbert HA, Nussbaum H, Hintz BL.

Cancer. 1981 Sep 15;48(6):1492-5.

PMID:
7272970

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