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Design, synthesis and biological evaluation of antimicrobial diarylimine and -amine compounds targeting the interaction between the bacterial NusB and NusE proteins.

Qiu Y, Chan ST, Lin L, Shek TL, Tsang TF, Barua N, Zhang Y, Ip M, Chan PK, Blanchard N, Hanquet G, Zuo Z, Yang X, Ma C.

Eur J Med Chem. 2019 Jun 3;178:214-231. doi: 10.1016/j.ejmech.2019.05.090. [Epub ahead of print]


Faecal microbiota transplantation for treatment of recurrent or refractory Clostridioides difficile infection in Hong Kong.

Lui RN, Wong SH, Lau LHS, Chan TT, Cheung KCY, Li A, Chin ML, Tang W, Ching JYL, Lam KLY, Chan PKS, Wu JCY, Sung JJY, Chan FKL, Ng SC.

Hong Kong Med J. 2019 Jun;25(3):178-182. doi: 10.12809/hkmj197855. Epub 2019 May 29.


Unicompartmental knee arthroplasties in Hong Kong: 15 years of experience in a teaching hospital.

Yung CS, Cheung MH, Fu HCH, Chan PK, Yan CH, Chiu KY.

J Orthop Surg (Hong Kong). 2019 May-Aug;27(2):2309499019850364. doi: 10.1177/2309499019850364.


Ten- to Sixteen-Year Follow-Up of Highly Cross-Linked Polyethylene in Total Hip Arthroplasty: What Factors Affect Wear?

Cheung A, Yan CH, Fu H, Cheung MH, Chan PK, Chiu KY.

J Arthroplasty. 2019 May 6. pii: S0883-5403(19)30409-7. doi: 10.1016/j.arth.2019.04.041. [Epub ahead of print]


Solution-Phase Epitaxial Growth of Perovskite Films on 2D Material Flakes for High-Performance Solar Cells.

Tang G, You P, Tai Q, Yang A, Cao J, Zheng F, Zhou Z, Zhao J, Chan PKL, Yan F.

Adv Mater. 2019 Jun;31(24):e1807689. doi: 10.1002/adma.201807689. Epub 2019 Apr 29.


Non-surgical treatment of knee osteoarthritis.

Kan HS, Chan PK, Chiu KY, Yan CH, Yeung SS, Ng YL, Shiu KW, Ho T.

Hong Kong Med J. 2019 Apr;25(2):127-133. doi: 10.12809/hkmj187600. Epub 2019 Mar 28. Review.


Liquid biopsy of HPV DNA in cervical cancer.

Cheung TH, Yim SF, Yu MY, Worley MJ Jr, Fiascone SJ, Chiu RWK, Lo KWK, Siu NSS, Wong MCS, Yeung ACM, Wong RRY, Chen ZG, Elias KM, Chung TKH, Berkowitz RS, Wong YF, Chan PKS.

J Clin Virol. 2019 May;114:32-36. doi: 10.1016/j.jcv.2019.03.005. Epub 2019 Mar 12.


Extended Experience in the Use of Antibiotic Lock for Eradication of Biofilm Bacteria on Tenckhoff Catheter.

Wong SS, Lau WY, Chan PK, Wan CK, Cheng YL.

Perit Dial Int. 2019 Mar-Apr;39(2):187-190. doi: 10.3747/pdi.2018.00098.


Small contact resistance and high-frequency operation of flexible low-voltage inverted coplanar organic transistors.

Borchert JW, Peng B, Letzkus F, Burghartz JN, Chan PKL, Zojer K, Ludwigs S, Klauk H.

Nat Commun. 2019 Mar 8;10(1):1119. doi: 10.1038/s41467-019-09119-8.


Gut mucosal virome alterations in ulcerative colitis.

Zuo T, Lu XJ, Zhang Y, Cheung CP, Lam S, Zhang F, Tang W, Ching JYL, Zhao R, Chan PKS, Sung JJY, Yu J, Chan FKL, Cao Q, Sheng JQ, Ng SC.

Gut. 2019 Jul;68(7):1169-1179. doi: 10.1136/gutjnl-2018-318131. Epub 2019 Mar 6.


Impact of Preservation Method and 16S rRNA Hypervariable Region on Gut Microbiota Profiling.

Chen Z, Hui PC, Hui M, Yeoh YK, Wong PY, Chan MCW, Wong MCS, Ng SC, Chan FKL, Chan PKS.

mSystems. 2019 Feb 26;4(1). pii: e00271-18. doi: 10.1128/mSystems.00271-18. eCollection 2019 Jan-Feb.


The Extended C-Terminal Region of Influenza C Virus Nucleoprotein Is Important for Nuclear Import and Ribonucleoprotein Activity.

Tang YS, Lo CY, Mok CK, Chan PK, Shaw PC.

J Virol. 2019 Apr 17;93(9). pii: e02048-18. doi: 10.1128/JVI.02048-18. Print 2019 May 1.


Role of polycyclic aromatic hydrocarbons as a co-factor in human papillomavirus-mediated carcinogenesis.

Zhang C, Luo Y, Zhong R, Law PTY, Boon SS, Chen Z, Wong CH, Chan PKS.

BMC Cancer. 2019 Feb 11;19(1):138. doi: 10.1186/s12885-019-5347-4.


Human Cardiac Ventricular-Like Organoid Chambers and Tissue Strips From Pluripotent Stem Cells as a Two-Tiered Assay for Inotropic Responses.

Keung W, Chan PKW, Backeris PC, Lee EK, Wong N, Wong AOT, Wong GKY, Chan CWY, Fermini B, Costa KD, Li RA.

Clin Pharmacol Ther. 2019 Feb 5. doi: 10.1002/cpt.1385. [Epub ahead of print]


Are reusable blood collection tube holders the culprit for nosocomial hepatitis C virus transmission?

Tsang DNC, Ip M, Chan PKS, Ching PTY, Lam HS, Seto WH.

Infect Control Hosp Epidemiol. 2019 Feb;40(2):250-251. doi: 10.1017/ice.2018.302. No abstract available.


Oncogenicitiy Comparison of Human Papillomavirus Type 52 E6 Variants.

Lai TO, Boon SS, Law PT, Chen Z, Thomas M, Banks L, Chan PK.

J Gen Virol. 2019 Mar;100(3):484-496. doi: 10.1099/jgv.0.001222. Epub 2019 Jan 24.


Economic Analysis of Herpes Zoster in a Hospital Setting in Hong Kong.

Ming WK, Yu WY, Tsang OT, Chan PK, You JH.

Acta Derm Venereol. 2019 May 1;99(6):616-617. doi: 10.2340/00015555-3118. No abstract available.


Impact of inter- and intra-individual variation, sample storage and sampling fraction on human stool microbial community profiles.

Yeoh YK, Chen Z, Hui M, Wong MCS, Ho WCS, Chin ML, Ng SC, Chan FKL, Chan PKS.

PeerJ. 2019 Jan 11;7:e6172. doi: 10.7717/peerj.6172. eCollection 2019.


Systematic review with meta-analysis: review of donor features, procedures and outcomes in 168 clinical studies of faecal microbiota transplantation.

Lai CY, Sung J, Cheng F, Tang W, Wong SH, Chan PKS, Kamm MA, Sung JJY, Kaplan G, Chan FKL, Ng SC.

Aliment Pharmacol Ther. 2019 Feb;49(4):354-363. doi: 10.1111/apt.15116. Epub 2019 Jan 9. Review.


Optimal gender-specific age for cost-effective vaccination with adjuvanted herpes zoster subunit vaccine in Chinese adults.

You JHS, Ming WK, Tsang OT, Chan PK.

PLoS One. 2019 Jan 4;14(1):e0210005. doi: 10.1371/journal.pone.0210005. eCollection 2019.


Oncogenic comparison of human papillomavirus type 58 E7 variants.

Law PT, Boon SS, Hu C, Lung RW, Cheung GP, Ho WC, Chen Z, Massimi P, Thomas M, Pim D, Banks L, Chan PK.

J Cell Mol Med. 2019 Feb;23(2):1517-1527. doi: 10.1111/jcmm.14059. Epub 2018 Dec 21.


Recombinant DENV 2 NS5: An effective antigen for diagnosis of DENV infection.

Zhang T, Wang ML, Zhang GR, Liu W, Xiao XQ, Yang YS, Li JT, Xun ZM, Li DY, Chan PKS.

J Virol Methods. 2019 Mar;265:35-41. doi: 10.1016/j.jviromet.2018.12.005. Epub 2018 Dec 16.


Higher Viral Load of Emerging Norovirus GII.P16-GII.2 than Pandemic GII.4 and Epidemic GII.17, Hong Kong, China.

Cheung SKC, Kwok K, Zhang LY, Mohammad KN, Lui GCY, Lee N, Nelson EAS, Lai RWM, Leung TF, Chan PKS, Chan MC.

Emerg Infect Dis. 2019 Jan;25(1):119-122. doi: 10.3201/eid2501.180395.


Complete Genome Sequences of Six Novel Macaca mulatta Papillomavirus Types Isolated from Genital Sites of Rhesus Monkeys in Hong Kong SAR, China.

Long T, Wong PY, Ho WCS, Burk RD, Chan PKS, Chen Z.

Microbiol Resour Announc. 2018 Dec 6;7(22). pii: e01414-18. doi: 10.1128/MRA.01414-18. eCollection 2018 Dec.


MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

Kalkat M, Resetca D, Lourenco C, Chan PK, Wei Y, Shiah YJ, Vitkin N, Tong Y, Sunnerhagen M, Done SJ, Boutros PC, Raught B, Penn LZ.

Mol Cell. 2018 Dec 6;72(5):836-848.e7. doi: 10.1016/j.molcel.2018.09.031. Epub 2018 Nov 8.


Niche adaptation and viral transmission of human papillomaviruses from archaic hominins to modern humans.

Chen Z, DeSalle R, Schiffman M, Herrero R, Wood CE, Ruiz JC, Clifford GM, Chan PKS, Burk RD.

PLoS Pathog. 2018 Nov 1;14(11):e1007352. doi: 10.1371/journal.ppat.1007352. eCollection 2018 Nov.


Diversity of macaque microbiota compared to the human counterparts.

Chen Z, Yeoh YK, Hui M, Wong PY, Chan MCW, Ip M, Yu J, Burk RD, Chan FKL, Chan PKS.

Sci Rep. 2018 Oct 22;8(1):15573. doi: 10.1038/s41598-018-33950-6.


Comparison of high-flow nasal cannula versus oxygen face mask for environmental bacterial contamination in critically ill pneumonia patients: a randomized controlled crossover trial.

Leung CCH, Joynt GM, Gomersall CD, Wong WT, Lee A, Ling L, Chan PKS, Lui PCW, Tsoi PCY, Ling CM, Hui M.

J Hosp Infect. 2019 Jan;101(1):84-87. doi: 10.1016/j.jhin.2018.10.007. Epub 2018 Oct 15.


Diagnostic Outcomes of Childhood ADHD in Chinese Adults.

Mak ADP, Chan AKW, Chan PKL, Tang CP, Lai K, Wong S, Leung P, Hung SF, Lam LCW, Lee S.

J Atten Disord. 2018 Sep 27:1087054718802015. doi: 10.1177/1087054718802015. [Epub ahead of print]


Inch-Scale Grain Boundary Free Organic Crystals Developed by Nucleation Seed-Controlled Shearing Method.

Zhou Z, Zhang Z, Wu Q, Ji X, Wang J, Zeng X, Feng SP, Chan PKL.

ACS Appl Mater Interfaces. 2018 Oct 17;10(41):35395-35403. doi: 10.1021/acsami.8b09655. Epub 2018 Oct 5.


Surveillance of human- and swine-origin influenza in Hong Kong children.

Leung TF, Chan PK, Hon KL, Li AM.

Hong Kong Med J. 2018 Oct;24 Suppl 6(5):16-18. No abstract available.


Influenza surveillance and vaccination in Hong Kong children.

Leung TF, Chan PK, Hon KL, Li AM, Cheng FW.

Hong Kong Med J. 2018 Oct;24 Suppl 6(5):8-11. No abstract available.


Frequent Genetic Mismatch between Vaccine Strains and Circulating Seasonal Influenza Viruses, Hong Kong, China, 1996-2012.

Chan MCW, Wang MH, Chen Z, Hui DSC, Kwok AK, Yeung ACM, Liu KM, Yeoh YK, Lee N, Chan PKS.

Emerg Infect Dis. 2018 Oct;24(10):1825-1834. doi: 10.3201/eid2410.180652.


Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection.

Zuo T, Wong SH, Cheung CP, Lam K, Lui R, Cheung K, Zhang F, Tang W, Ching JYL, Wu JCY, Chan PKS, Sung JJY, Yu J, Chan FKL, Ng SC.

Nat Commun. 2018 Sep 10;9(1):3663. doi: 10.1038/s41467-018-06103-6.


MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability.

Dingar D, Tu WB, Resetca D, Lourenco C, Tamachi A, De Melo J, Houlahan KE, Kalkat M, Chan PK, Boutros PC, Raught B, Penn LZ.

Nat Commun. 2018 Aug 29;9(1):3502. doi: 10.1038/s41467-018-05660-0.


A Pilot Study of the Effectiveness of Lithium Versus Quetiapine Immediate Release Monotherapy in Patients With Bipolar Spectrum Disorders.

Gao K, Goto T, Yuan C, Brownrigg B, Conroy C, Chan PK, Serrano MB, Ganocy SJ, Fang F, Calabrese JR.

J Clin Psychopharmacol. 2018 Oct;38(5):422-434. doi: 10.1097/JCP.0000000000000927.


First case of neurofibromatosis with posterior reversible encephalopathy syndrome showing spinal cord involvement.

Chan PKJ, Tse KS, Fok WSE, Poon WL.

Indian J Radiol Imaging. 2018 Apr-Jun;28(2):161-164. doi: 10.4103/ijri.IJRI_320_17.


Prevalence and Epidemiologic Profile of Oral Infection with Alpha, Beta, and Gamma Papillomaviruses in an Asian Chinese Population.

Wong MCS, Vlantis AC, Liang M, Wong PY, Ho WCS, Boon SS, Sze RKH, Leung C, Chan PKS, Chen Z.

J Infect Dis. 2018 Jul 2;218(3):388-397. doi: 10.1093/infdis/jiy160.


Potential cost-effectiveness of adjuvanted herpes zoster subunit vaccine for older adults in Hong Kong.

You JHS, Ming WK, Lee CF, Tsang OT, Chan PK.

Vaccine. 2018 Jul 25;36(31):4610-4620. doi: 10.1016/j.vaccine.2018.06.049. Epub 2018 Jun 27.


Smart Surgical Catheter for C-Reactive Protein Sensing Based on an Imperceptible Organic Transistor.

Ji X, Zhou P, Zhong L, Xu A, Tsang ACO, Chan PKL.

Adv Sci (Weinh). 2018 May 2;5(6):1701053. doi: 10.1002/advs.201701053. eCollection 2018 Jun.


ICTV Virus Taxonomy Profile: Papillomaviridae.

Van Doorslaer K, Chen Z, Bernard HU, Chan PKS, DeSalle R, Dillner J, Forslund O, Haga T, McBride AA, Villa LL, Burk RD, Ictv Report Consortium.

J Gen Virol. 2018 Aug;99(8):989-990. doi: 10.1099/jgv.0.001105. Epub 2018 Jun 21.


Erratum for Chen et al., "Complete Genome Sequence of a Novel Human Papillomavirus Isolated from Oral Rinse".

Chen Z, Wong MCS, Wong PY, Ho WCS, Liang M, Yeung ACM, Chan PKS.

Genome Announc. 2018 May 31;6(22). pii: e00485-18. doi: 10.1128/genomeA.00485-18. No abstract available.


Dual-Gated Transistor Platform for On-Site Detection of Lead Ions at Trace Levels.

Venkatesh S, Li T, Wang XS, Yeung CC, Pei K, Sun QJ, Wu W, Li RKY, Lam MHW, Chan PKL, Wylie JJ, Roy VAL.

Anal Chem. 2018 Jun 19;90(12):7399-7405. doi: 10.1021/acs.analchem.8b00841. Epub 2018 May 29.


Three decades of neonatal vaccination has greatly reduced antenatal prevalence of hepatitis B virus infection among gravidae covered by the program.

Lao TT, Sahota DS, Chan PKS.

J Infect. 2018 Jun;76(6):543-549. doi: 10.1016/j.jinf.2018.04.003. Epub 2018 May 6.


Influenza vaccine effectiveness in hospitalised Hong Kong children: Feasibility of estimates from routine surveillance data.

Yeung KHT, Chan KCC, Chan PKS, Lam DSY, Sham PCO, Yau YS, Chan WH, Chiu WK, Ng KL, Ng DKK, Chan IMC, Nelson EAS.

Vaccine. 2018 Jun 7;36(24):3477-3485. doi: 10.1016/j.vaccine.2018.04.081. Epub 2018 May 5.


Age-specific seroprevalence of dengue infection in Hong Kong.

Lee P, Yeung ACM, Chen Z, Chan MCW, Sze KH, Chan PKS.

J Med Virol. 2018 Sep;90(9):1427-1430. doi: 10.1002/jmv.25216. Epub 2018 May 25.


Alterations in Enteric Virome Are Associated With Colorectal Cancer and Survival Outcomes.

Nakatsu G, Zhou H, Wu WKK, Wong SH, Coker OO, Dai Z, Li X, Szeto CH, Sugimura N, Lam TY, Yu AC, Wang X, Chen Z, Wong MC, Ng SC, Chan MTV, Chan PKS, Chan FKL, Sung JJ, Yu J.

Gastroenterology. 2018 Aug;155(2):529-541.e5. doi: 10.1053/j.gastro.2018.04.018. Epub 2018 Apr 22.


Bacteriology and risk factors associated with periprosthetic joint infection after primary total knee arthroplasty: retrospective study of 2543 cases.

Siu KT, Ng FY, Chan PK, Fu HC, Yan CH, Chiu KY.

Hong Kong Med J. 2018 Apr;24(2):152-157. doi: 10.12809/hkmj176885.


Corrigendum to "General distress is more important than PTSD's cognitions and mood alterations factor in accounting for PTSD and depression's comorbidity" [J. Affect. Disord. 211 (2017) 118-123].

Byllesby BM, Elhai JD, Tamburrino M, Fine TH, Cohen G, Sampson L, Shirley E, Chan PK, Liberzon I, Galea S, Calabrese JR.

J Affect Disord. 2018 Jul;234:289. doi: 10.1016/j.jad.2018.03.004. Epub 2018 Mar 21. No abstract available.


Uptake of human papillomavirus (HPV) vaccination in Hong Kong: Facilitators and barriers among adolescent girls and their parents.

Yuen WWY, Lee A, Chan PKS, Tran L, Sayko E.

PLoS One. 2018 Mar 15;13(3):e0194159. doi: 10.1371/journal.pone.0194159. eCollection 2018.

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