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Adherence to the Malaysian clinical practice guideline for depression by general practitioners in private practice in Penang.

Ho KC, Russell V, Nyanti L, Chan MW, Hassali MA, Dawood OT, Subramaniam K, O'Brien FM.

Asian J Psychiatr. 2019 Dec 9;48:101899. doi: 10.1016/j.ajp.2019.101899. [Epub ahead of print]


Dendritic cell upregulation of programmed death ligand-1 via DNA demethylation inhibits experimental autoimmune encephalomyelitis.

Chang CB, Lee SP, Chen WM, Wang CM, Song YC, Chan MW, Wu SF.

J Autoimmun. 2019 Nov 28:102362. doi: 10.1016/j.jaut.2019.102362. [Epub ahead of print]


A Comparative Study of Respiratory Quality of Life among Firefighters, Traffic Police and Other Occupations in Malaysia.

Chean KY, Abdulrahman S, Chan MW, Tan KC.

Int J Occup Environ Med. 2019 Oct;10(4):203-215. doi: 10.15171/ijoem.2019.1657.


Editor's Note: Hemolytic E. coli Promotes Colonic Tumorigenesis in Females.

Jin Y, Tang S, Li W, Ng SC, Chan MWY, Sung JJY, Yu J.

Cancer Res. 2019 Oct 1;79(19):5126. doi: 10.1158/0008-5472.CAN-19-2442. No abstract available.


c-Myc Acts as a Competing Endogenous RNA to Sponge miR-34a, in the Upregulation of CD44, in Urothelial Carcinoma.

Chen PC, Yu CC, Huang WY, Huang WH, Chuang YM, Lin RI, Lin JMJ, Lin HY, Jou YC, Shen CH, Chan MWY.

Cancers (Basel). 2019 Sep 28;11(10). pii: E1457. doi: 10.3390/cancers11101457.


The mediating roles of social benefits and social influence on the relationships between collectivism, power distance, and influenza vaccination among Hong Kong nurses: A cross-sectional study.

Li KK, Chan MWH, Lee SS, Kwok KO.

Int J Nurs Stud. 2019 Nov;99:103359. doi: 10.1016/j.ijnurstu.2019.05.007. Epub 2019 May 21.


Multidisciplinary education approach to optimize phosphate control among hemodialysis patients.

Chan MW, Cheah HM, Mohd Padzil MB.

Int J Clin Pharm. 2019 Oct;41(5):1282-1289. doi: 10.1007/s11096-019-00878-4. Epub 2019 Jul 13.


Paired Box-1 (PAX1) Activates Multiple Phosphatases and Inhibits Kinase Cascades in Cervical Cancer.

Su PH, Lai HC, Huang RL, Chen LY, Wang YC, Wu TI, Chan MWY, Liao CC, Chen CW, Lin WY, Chang CC.

Sci Rep. 2019 Jun 24;9(1):9195. doi: 10.1038/s41598-019-45477-5.


Methylomics analysis identifies a putative STAT3 target, SPG20, as a noninvasive epigenetic biomarker for early detection of gastric cancer.

Wei KL, Chou JL, Chen YC, Jin H, Chuang YM, Wu CS, Chan MWY.

PLoS One. 2019 Jun 13;14(6):e0218338. doi: 10.1371/journal.pone.0218338. eCollection 2019.


Adolescent Internet Addiction in Hong Kong: Prevalence, Psychosocial Correlates, and Prevention.

Chung TWH, Sum SMY, Chan MWL.

J Adolesc Health. 2019 Jun;64(6S):S34-S43. doi: 10.1016/j.jadohealth.2018.12.016. Review.


A Prospective Study in the Treatment of Lentigines in Asian Skin Using 532 nm Picosecond Nd:YAG Laser.

Chan MWM, Shek SY, Yeung CK, Chan HH.

Lasers Surg Med. 2019 Nov;51(9):767-773. doi: 10.1002/lsm.23103. Epub 2019 May 21.


TET1 reprograms the epithelial ovarian cancer epigenome and reveals casein kinase 2α as a therapeutic target.

Chen LY, Huang RL, Chan MW, Yan PS, Huang TS, Wu RC, Suryo Rahmanto Y, Su PH, Weng YC, Chou JL, Chao TK, Wang YC, Shih IM, Lai HC.

J Pathol. 2019 Jul;248(3):363-376. doi: 10.1002/path.5266. Epub 2019 Apr 23.


Recent progress on developing exogenous monocyte/macrophage-based therapies for inflammatory and degenerative diseases.

Chan MWY, Viswanathan S.

Cytotherapy. 2019 Apr;21(4):393-415. doi: 10.1016/j.jcyt.2019.02.002. Epub 2019 Mar 12. Review.


Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming.

Xiong L, Wu F, Wu Q, Xu L, Cheung OK, Kang W, Mok MT, Szeto LLM, Lun CY, Lung RW, Zhang J, Yu KH, Lee SD, Huang G, Wang CM, Liu J, Yu Z, Yu DY, Chou JL, Huang WH, Feng B, Cheung YS, Lai PB, Tan P, Wong N, Chan MW, Huang TH, Yip KY, Cheng AS, To KF.

Nat Commun. 2019 Jan 18;10(1):335. doi: 10.1038/s41467-018-08245-z.


ZNF671 DNA methylation as a molecular predictor for the early recurrence of serous ovarian cancer.

Mase S, Shinjo K, Totani H, Katsushima K, Arakawa A, Takahashi S, Lai HC, Lin RI, Chan MWY, Sugiura-Ogasawara M, Kondo Y.

Cancer Sci. 2019 Mar;110(3):1105-1116. doi: 10.1111/cas.13936. Epub 2019 Jan 31.


E2F6 functions as a competing endogenous RNA, and transcriptional repressor, to promote ovarian cancer stemness.

Cheng FHC, Lin HY, Hwang TW, Chen YC, Huang RL, Chang CB, Yang W, Lin RI, Lin CW, Chen GCW, Mai SY, Lin JMJ, Chuang YM, Chou JL, Kuo LW, Li C, Cheng ASL, Lai HC, Wu SF, Tsai JC, Chan MWY.

Cancer Sci. 2019 Mar;110(3):1085-1095. doi: 10.1111/cas.13920. Epub 2019 Jan 25.


Project Octo-Pills-Engaging community pharmacists in the care of patients from a tertiary hospital: A pilot study.

Neo ZY, Low YT, Ong KY, Chong JBK, Lim KW, Chan MW, Lim AZN, Mamun K, Chen LL.

Int J Health Plann Manage. 2019 Jan;34(1):e976-e986. doi: 10.1002/hpm.2718. Epub 2018 Nov 29.


GATA3 as a master regulator and therapeutic target in ovarian high-grade serous carcinoma stem cells.

Chen HJ, Huang RL, Liew PL, Su PH, Chen LY, Weng YC, Chang CC, Wang YC, Chan MW, Lai HC.

Int J Cancer. 2018 Dec 15;143(12):3106-3119. doi: 10.1002/ijc.31750. Epub 2018 Oct 3.


Neonatal Dexamethasone Treatment Suppresses Hippocampal Estrogen Receptor α Expression in Adolescent Female Rats.

Chiu HF, Chan MWY, Cheng CY, Chou JL, Lin JM, Yang YL, Lu KT.

Mol Neurobiol. 2019 Mar;56(3):2224-2233. doi: 10.1007/s12035-018-1214-6. Epub 2018 Jul 13.


Epigenetic Biomarkers in Cancer.

Cheng YY, Jin HC, Chan MWY, Chu WK, Grusch M.

Dis Markers. 2018 Feb 20;2018:4987103. doi: 10.1155/2018/4987103. eCollection 2018. No abstract available.


DNA Methylation as a Noninvasive Epigenetic Biomarker for the Detection of Cancer.

Leygo C, Williams M, Jin HC, Chan MWY, Chu WK, Grusch M, Cheng YY.

Dis Markers. 2017;2017:3726595. doi: 10.1155/2017/3726595. Epub 2017 Sep 5. Review.


Epigenetic silencing of the dual-role signal mediator, ANGPTL4 in tumor tissues and its overexpression in the urothelial carcinoma microenvironment.

Hsieh HY, Jou YC, Tung CL, Tsai YS, Wang YH, Chi CL, Lin RI, Hung SK, Chuang YM, Wu SF, Li C, Shen CH, Chan MWY, Hsu CD.

Oncogene. 2018 Feb 1;37(5):673-686. doi: 10.1038/onc.2017.375. Epub 2017 Oct 16.


Irradiation enhanced risks of hospitalised pneumonopathy in lung cancer patients: a population-based surgical cohort study.

Hung SK, Chen YC, Chiou WY, Lai CL, Lee MS, Lo YC, Chen LC, Huang LW, Chien NC, Li SC, Liu DW, Hsu FC, Tsai SJ, Chan MW, Lin HY.

BMJ Open. 2017 Sep 27;7(9):e015022. doi: 10.1136/bmjopen-2016-015022.


Venous, Arterialized-Venous, or Capillary Glucose Reference Measurements for the Accuracy Assessment of a Continuous Glucose Monitoring System.

Kropff J, van Steen SC, deGraaff P, Chan MW, van Amstel RBE, DeVries JH.

Diabetes Technol Ther. 2017 Nov;19(11):609-617. doi: 10.1089/dia.2017.0189. Epub 2017 Aug 22.


Hard clam extracts induce atypical apoptosis in human gastric cancer cells.

Song EJ, Chan MWY, Shin JW, Chen CC.

Exp Ther Med. 2017 Aug;14(2):1409-1418. doi: 10.3892/etm.2017.4630. Epub 2017 Jun 20.


Safety of Acupuncture: Overview of Systematic Reviews.

Chan MWC, Wu XY, Wu JCY, Wong SYS, Chung VCH.

Sci Rep. 2017 Jun 13;7(1):3369. doi: 10.1038/s41598-017-03272-0.


Dust mite allergen-specific immunotherapy increases IL4 DNA methylation and induces Der p-specific T cell tolerance in children with allergic asthma.

Wang CM, Chang CB, Chan MW, Wen ZH, Wu SF.

Cell Mol Immunol. 2018 Nov;15(11):963-972. doi: 10.1038/cmi.2017.26. Epub 2017 Jun 26.


Morphologic and topographic radiologic features of human papillomavirus-related and -unrelated oropharyngeal carcinoma.

Chan MW, Yu E, Bartlett E, O'Sullivan B, Su J, Waldron J, Ringash J, Bratman SV, Chen YA, Irish J, Kim J, Gullane P, Gilbert R, Chepeha D, Perez-Ordonez B, Weinreb I, Hansen A, Tong L, Xu W, Huang SH.

Head Neck. 2017 Aug;39(8):1524-1534. doi: 10.1002/hed.24764. Epub 2017 Jun 5.


18F-FDG uptake in the colon is modulated by metformin but not associated with core body temperature and energy expenditure.

Bahler L, Holleman F, Chan MW, Booij J, Hoekstra JB, Verberne HJ.

PLoS One. 2017 May 2;12(5):e0176242. doi: 10.1371/journal.pone.0176242. eCollection 2017.


Single vagus nerve stimulation reduces early postprandial C-peptide levels but not other hormones or postprandial metabolism.

Tang MW, van Nierop FS, Koopman FA, Eggink HM, Gerlag DM, Chan MW, Zitnik R, Vaz FM, Romijn JA, Tak PP, Soeters MR.

Clin Rheumatol. 2018 Feb;37(2):505-514. doi: 10.1007/s10067-017-3618-5. Epub 2017 Apr 8.


Recurrent Tongue Masses in a Young Boy.

Chan MW, Gopwani P.

JAMA Pediatr. 2017 Jun 1;171(6):593-594. doi: 10.1001/jamapediatrics.2017.0288. No abstract available.


Radiologic Differences between Human Papillomavirus-Related and Human Papillomavirus-Unrelated Oropharyngeal Carcinoma on Diffusion-Weighted Imaging.

Chan MW, Higgins K, Enepekides D, Poon I, Symons SP, Moineddin R, Weinreb I, Shearkhani O, Chen A, Beelen J, Chan A, Maralani PJ.

ORL J Otorhinolaryngol Relat Spec. 2016;78(6):344-352. doi: 10.1159/000458446. Epub 2017 Mar 1.


SH2B1 modulates chromatin state and MyoD occupancy to enhance expressions of myogenic genes.

Chen KW, Chang YJ, Yeh CM, Lian YL, Chan MW, Kao CF, Chen L.

Biochim Biophys Acta Gene Regul Mech. 2017 Feb;1860(2):270-281. doi: 10.1016/j.bbagrm.2016.12.007. Epub 2016 Dec 27.


The effect of multimedia replacing text in resident clinical decision-making assessment.

Chang TP, Schrager SM, Rake AJ, Chan MW, Pham PK, Christman G.

Adv Health Sci Educ Theory Pract. 2017 Oct;22(4):901-914. doi: 10.1007/s10459-016-9719-0. Epub 2016 Oct 17.


Aberrant JAK/STAT Signaling Suppresses TFF1 and TFF2 through Epigenetic Silencing of GATA6 in Gastric Cancer.

Wu CS, Wei KL, Chou JL, Lu CK, Hsieh CC, Lin JM, Deng YF, Hsu WT, Wang HM, Leung CH, Ma DL, Li C, Chan MW.

Int J Mol Sci. 2016 Sep 2;17(9). pii: E1467. doi: 10.3390/ijms17091467.


Significant symptoms alleviation and tumor volume reduction after combined simultaneously integrated inner-escalated boost and volumetric-modulated arc radiotherapy in a patient with unresectable bulky hepatocellular carcinoma: A care-compliant case report.

Lin YH, Hung SK, Chiou WY, Lee MS, Shen BJ, Chen LC, Liu DW, Tsai WT, Lin PH, Shih YT, Hsu FC, Tsai SJ, Chan MW, Lin HY.

Medicine (Baltimore). 2016 Aug;95(34):e4717. doi: 10.1097/MD.0000000000004717.


Epigenetic silencing of the NR4A3 tumor suppressor, by aberrant JAK/STAT signaling, predicts prognosis in gastric cancer.

Yeh CM, Chang LY, Lin SH, Chou JL, Hsieh HY, Zeng LH, Chuang SY, Wang HW, Dittner C, Lin CY, Lin JM, Huang YT, Ng EK, Cheng AS, Wu SF, Lin J, Yeh KT, Chan MW.

Sci Rep. 2016 Aug 16;6:31690. doi: 10.1038/srep31690.


Hemolytic E. coli Promotes Colonic Tumorigenesis in Females.

Jin Y, Tang S, Li W, Ng SC, Chan MW, Sung JJ, Yu J.

Cancer Res. 2016 May 15;76(10):2891-900. doi: 10.1158/0008-5472.CAN-15-2083. Epub 2016 Mar 24. Erratum in: Cancer Res. 2019 Oct 1;79(19):5126.


Guizhi Fuling Wan as a Novel Agent for Intravesical Treatment for Bladder Cancer in a Mouse Model.

Lu CC, Shen CH, Chang CB, Hsieh HY, Wu JD, Tseng LH, Hwang DW, Chen SY, Wu SF, Chan MWY, Hsu CD.

Mol Med. 2016 Sep;22:64-73. doi: 10.2119/molmed.2015.00085. Epub 2016 Jan 13.


Dysregulated Lysine Acetyltransferase 2B Promotes Inflammatory Bowel Disease Pathogenesis Through Transcriptional Repression of Interleukin-10.

Bai AH, Wu WK, Xu L, Wong SH, Go MY, Chan AW, Harbord M, Zhang S, Chen M, Wu JC, Chan MW, Chan MT, Chan FK, Sung JJ, Yu J, Cheng AS, Ng SC.

J Crohns Colitis. 2016 Jun;10(6):726-34. doi: 10.1093/ecco-jcc/jjw020. Epub 2016 Jan 22.


Oncogene-tumor suppressor gene feedback interactions and their control.

Aguda BD, del Rosario RC, Chan MW.

Math Biosci Eng. 2015 Dec;12(6):1277-88. doi: 10.3934/mbe.2015.12.1277.


Patterns of epidural progression following postoperative spine stereotactic body radiotherapy: implications for clinical target volume delineation.

Chan MW, Thibault I, Atenafu EG, Yu E, John Cho BC, Letourneau D, Lee Y, Yee A, Fehlings MG, Sahgal A.

J Neurosurg Spine. 2016 Apr;24(4):652-9. doi: 10.3171/2015.6.SPINE15294. Epub 2015 Dec 18.


Cyproheptadine exhibits antitumor activity in urothelial carcinoma cells by targeting GSK3β to suppress mTOR and β-catenin signaling pathways.

Hsieh HY, Shen CH, Lin RI, Feng YM, Huang SY, Wang YH, Wu SF, Hsu CD, Chan MW.

Cancer Lett. 2016 Jan 1;370(1):56-65. doi: 10.1016/j.canlet.2015.09.018. Epub 2015 Oct 21.


Methylomics analysis identifies ZNF671 as an epigenetically repressed novel tumor suppressor and a potential non-invasive biomarker for the detection of urothelial carcinoma.

Yeh CM, Chen PC, Hsieh HY, Jou YC, Lin CT, Tsai MH, Huang WY, Wang YT, Lin RI, Chen SS, Tung CL, Wu SF, Chang DC, Shen CH, Hsu CD, Chan MW.

Oncotarget. 2015 Oct 6;6(30):29555-72. doi: 10.18632/oncotarget.4986.


Epigenetic silencing of GDF1 disrupts SMAD signaling to reinforce gastric cancer development.

Yang W, Mok MT, Li MS, Kang W, Wang H, Chan AW, Chou JL, Chen J, Ng EK, To KF, Yu J, Chan MW, Chan FK, Sung JJ, Cheng AS.

Oncogene. 2016 Apr 21;35(16):2133-44. doi: 10.1038/onc.2015.276. Epub 2015 Jul 27.


Global profiling of histone modifications in the polyomavirus BK virion minichromosome.

Fang CY, Shen CH, Wang M, Chen PL, Chan MW, Hsu PH, Chang D.

Virology. 2015 Sep;483:1-12. doi: 10.1016/j.virol.2015.04.009. Epub 2015 May 15.


The effect of a virtual ward program on emergency services utilization and quality of life in frail elderly patients after discharge: a pilot study.

Leung DY, Lee DT, Lee IF, Lam LW, Lee SW, Chan MW, Lam YM, Leung SH, Chiu PC, Ho NK, Ip MF, Hui MM.

Clin Interv Aging. 2015 Feb 3;10:413-20. doi: 10.2147/CIA.S68937. eCollection 2015.


Hypermethylation of the TGF-β target, ABCA1 is associated with poor prognosis in ovarian cancer patients.

Chou JL, Huang RL, Shay J, Chen LY, Lin SJ, Yan PS, Chao WT, Lai YH, Lai YL, Chao TK, Lee CI, Tai CK, Wu SF, Nephew KP, Huang TH, Lai HC, Chan MW.

Clin Epigenetics. 2015 Jan 14;7:1. doi: 10.1186/s13148-014-0036-2. eCollection 2015.


DNA methylation profiles and biomarkers of oral squamous cell carcinoma.

Li YF, Hsiao YH, Lai YH, Chen YC, Chen YJ, Chou JL, Chan MW, Lin YH, Tsou YA, Tsai MH, Tai CK.

Epigenetics. 2015;10(3):229-36. doi: 10.1080/15592294.2015.1006506.


A mathematical model of bimodal epigenetic control of miR-193a in ovarian cancer stem cells.

Cheng FH, Aguda BD, Tsai JC, Kochańczyk M, Lin JM, Chen GC, Lai HC, Nephew KP, Hwang TW, Chan MW.

PLoS One. 2014 Dec 29;9(12):e116050. doi: 10.1371/journal.pone.0116050. eCollection 2014.

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