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Prenatal diagnosis of pathogenic genomic imbalance in fetuses with increased nuchal translucency but normal karyotyping using chromosomal microarray.

Leung TY, Au Yeung KC, Leung WC, Leung KY, Lo TK, To WWK, Lau WL, Chan LW, Sahota DS, Choy RKW.

Hong Kong Med J. 2019 Aug;25 Suppl 5(4):30-32. No abstract available.


The applications of metabolomics in the molecular diagnostics of cancer.

Cheung PK, Ma MH, Tse HF, Yeung KF, Tsang HF, Chu MKM, Kan CM, Cho WCS, Ng LBW, Chan LWC, Wong SCC.

Expert Rev Mol Diagn. 2019 Aug 15. doi: 10.1080/14737159.2019.1656530. [Epub ahead of print]


Computer-aided design of mastoparan-like peptides enables the generation of non-toxic variants with extended antibacterial properties.

Oshiro KGN, Cândido ES, Chan LY, Torres MT, Monges BED, Rodrigues SG, Porto WF, Ribeiro SM, Troeira Henriques S, Lu TK, de la Fuente-Nunez C, Craik DJ, Franco OL, Cardoso MH.

J Med Chem. 2019 Aug 14. doi: 10.1021/acs.jmedchem.9b00915. [Epub ahead of print]


The Association of Fenofibrate with Kidney Tubular Injury in a Subgroup of Participants in the ACCORD Trial.

Chauhan K, Nadkarni GN, Debnath N, Chan L, Saha A, Garg AX, Parikh CR, Coca SG.

Clin J Am Soc Nephrol. 2019 Aug 13. pii: CJN.00370119. doi: 10.2215/CJN.00370119. [Epub ahead of print] No abstract available.


Causative Factors for Complications in Transpalatal Advancement.

Chan L, Kitpornchai L, Mackay S.

Ann Otol Rhinol Laryngol. 2019 Aug 13:3489419867969. doi: 10.1177/0003489419867969. [Epub ahead of print]


Stability and Turnover of the ACTH Receptor Complex.

Clark AJL, Chan L.

Front Endocrinol (Lausanne). 2019 Jul 26;10:491. doi: 10.3389/fendo.2019.00491. eCollection 2019. Review.


Socio-ecological influences on political ideology.

Conway LG 3rd, Chan L, Woodard SR.

Curr Opin Psychol. 2019 Jul 15;32:76-80. doi: 10.1016/j.copsyc.2019.06.034. [Epub ahead of print] Review.


Resilience: insights from medical educators.

Chan L, Dennis AA.

Clin Teach. 2019 Aug;16(4):384-389. doi: 10.1111/tct.13058.


Rationale for targeting BCL6 in MLL-rearranged acute lymphoblastic leukemia.

Hurtz C, Chan LN, Geng H, Ballabio E, Xiao G, Deb G, Khoury H, Chen CW, Armstrong SA, Chen J, Ernst P, Melnick A, Milne T, Müschen M.

Genes Dev. 2019 Aug 8. doi: 10.1101/gad.327593.119. [Epub ahead of print]


Crucifera sulforaphane (SFN) inhibits the growth of nasopharyngeal carcinoma through DNA methyltransferase 1 (DNMT1)/Wnt inhibitory factor 1 (WIF1) axis.

Chen L, Chan LS, Lung HL, Yip TTC, Ngan RKC, Wong JWC, Lo KW, Ng WT, Lee AWM, Tsao GSW, Lung ML, Mak NK.

Phytomedicine. 2019 Jul 29;63:153058. doi: 10.1016/j.phymed.2019.153058. [Epub ahead of print]


Distribution of Neuroendocrine Marker-Positive Cells in Colorectal Cancer Tissue and Normal Mucosal Tissue: Consideration of Histogenesis of Neuroendocrine Cancer.

Ogimi T, Sadahiro S, Kamei Y, Chan LF, Miyakita H, Saito G, Okada K, Suzuki T, Kajiwara H.

Oncology. 2019 Aug 7:1-7. doi: 10.1159/000501521. [Epub ahead of print]


Copper Deficiency in Liver Diseases: A Case Series and Pathophysiological Considerations.

Yu L, Liou IW, Biggins SW, Yeh M, Jalikis F, Chan LN, Burkhead J.

Hepatol Commun. 2019 Jun 26;3(8):1159-1165. doi: 10.1002/hep4.1393. eCollection 2019 Aug.


Trends and Racial Disparities of Palliative Care Use among Hospitalized Patients with ESKD on Dialysis.

Wen Y, Jiang C, Koncicki HM, Horowitz CR, Cooper RS, Saha A, Coca SG, Nadkarni GN, Chan L.

J Am Soc Nephrol. 2019 Aug 6. pii: ASN.2018121256. doi: 10.1681/ASN.2018121256. [Epub ahead of print]


Electrochemical characteristics of microelectrode designed for electrical stimulation.

Cui H, Xie X, Xu S, Chan LLH, Hu Y.

Biomed Eng Online. 2019 Aug 1;18(1):86. doi: 10.1186/s12938-019-0704-8.


The Association between Mortality-to-Incidence Ratios and Health Expenditures in Brain and Nervous System Cancers.

Lee TH, Sung WW, Chan L, Lee HL, Chen SL, Huang YH, Kwan AL.

Int J Environ Res Public Health. 2019 Jul 31;16(15). pii: E2739. doi: 10.3390/ijerph16152739.


Differentiating Parkinson's disease motor subtypes using automated volume-based morphometry incorporating white matter and deep gray nuclear lesion load.

Fang E, Ann CN, Maréchal B, Lim JX, Tan SYZ, Li H, Gan J, Tan EK, Chan LL.

J Magn Reson Imaging. 2019 Jul 31. doi: 10.1002/jmri.26887. [Epub ahead of print]


Effect of Roughness on the Dispersion of Dry Powders for Inhalation: a Dynamic Visualization Perspective.

Kou X, Heng PWS, Chan LW, Wereley ST, Carvajal MT.

AAPS PharmSciTech. 2019 Jul 30;20(7):271. doi: 10.1208/s12249-019-1482-0.


Survival benefit of adjuvant radiotherapy in elderly patients with WHO grade Ⅲ meningioma.

Zhou H, Bai HX, Chan L, Zhang PJ, Karakousis G, Huang R, Xiao B, Yang L.

World Neurosurg. 2019 Jul 26. pii: S1878-8750(19)32046-7. doi: 10.1016/j.wneu.2019.07.140. [Epub ahead of print]


Divergent Effects of Resveratrol on Rat Cardiac Fibroblasts and Cardiomyocytes.

Lieben Louis X, Meikle Z, Chan L, DeGagne G, Cummer R, Meikle S, Krishnan S, Yu L, Netticadan T, Wigle JT.

Molecules. 2019 Jul 17;24(14). pii: E2604. doi: 10.3390/molecules24142604.


Plasma Amyloid Beta and Tau Levels Are Predictors of Post-stroke Cognitive Impairment: A Longitudinal Study.

Chi NF, Chao SP, Huang LK, Chan L, Chen YR, Chiou HY, Hu CJ.

Front Neurol. 2019 Jul 2;10:715. doi: 10.3389/fneur.2019.00715. eCollection 2019.


Correction to: The early identification of disease progression in patients with suspected infection presenting to the emergency department: a multi-centre derivation and validation study.

Saeed K, Wilson DC, Bloos F, Schuetz P, van der Does Y, Melander O, Hausfater P, Legramante JM, Claessens YE, Amin D, Rosenqvist M, White G, Mueller B, Limper M, Callejo CC, Brandi A, Macchi MA, Cortes N, Kutz A, Patka P, Yañez MC, Bernardini S, Beau N, Dryden M, van Gorp ECM, Minieri M, Chan L, Rood PPM, Del Castillo JG.

Crit Care. 2019 Jul 15;23(1):255. doi: 10.1186/s13054-019-2536-0.


IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion.

Chan LC, Li CW, Xia W, Hsu JM, Lee HH, Cha JH, Wang HL, Yang WH, Yen EY, Chang WC, Zha Z, Lim SO, Lai YJ, Liu C, Liu J, Dong Q, Yang Y, Sun L, Wei Y, Nie L, Hsu JL, Li H, Ye Q, Hassan MM, Amin HM, Kaseb AO, Lin X, Wang SC, Hung MC.

J Clin Invest. 2019 Jul 15;129(8):3324-3338. doi: 10.1172/JCI126022. eCollection 2019 Jul 15.


Proteomic profiling in liver cancer: another new page.

Chan LK, Ng IO.

Transl Gastroenterol Hepatol. 2019 Jun 21;4:47. doi: 10.21037/tgh.2019.06.03. eCollection 2019. No abstract available.


Tris(8-Hydroxyquinoline)iron induces apoptotic cell death via oxidative stress and by activating death receptor signaling pathway in human head and neck carcinoma cells.

Chan LP, Tseng YP, Ding HY, Pan SM, Chiang FY, Wang LF, Chou TH, Lien PJ, Liu C, Kuo PL, Liang CH.

Phytomedicine. 2019 Jun 30;63:153005. doi: 10.1016/j.phymed.2019.153005. [Epub ahead of print]


Archives Seeks to Improve Abstract Reporting Quality.

Heinemann AW, Chan L, Hoenig HM.

Arch Phys Med Rehabil. 2019 Jun 15. pii: S0003-9993(19)30394-6. doi: 10.1016/j.apmr.2019.05.027. [Epub ahead of print] No abstract available.


Impact of a probiotic product on bowel habits and microbial profile in participants with functional constipation: A randomized controlled trial.

Martoni CJ, Evans M, Chow CT, Chan LS, Leyer G.

J Dig Dis. 2019 Jul 4. doi: 10.1111/1751-2980.12797. [Epub ahead of print]


Neurocognitive Driving Rehabilitation in Virtual Environments (NeuroDRIVE): A pilot clinical trial for chronic traumatic brain injury.

Ettenhofer ML, Guise B, Brandler B, Bittner K, Gimbel SI, Cordero E, Nelson Schmitt S, Williams K, Cox D, Roy MJ, Chan L.

NeuroRehabilitation. 2019;44(4):531-544. doi: 10.3233/NRE-192718.


Antiparkinsonism anticholinergics increase dementia risk in patients with Parkinson's disease.

Hong CT, Chan L, Wu D, Chen WT, Chien LN.

Parkinsonism Relat Disord. 2019 Jun 25. pii: S1353-8020(19)30285-8. doi: 10.1016/j.parkreldis.2019.06.022. [Epub ahead of print]


Association between Ambulatory Status and Functional Disability in Elderly People with Dementia.

Lee HH, Hong CT, Wu D, Chi WC, Yen CF, Liao HF, Chan L, Liou TH.

Int J Environ Res Public Health. 2019 Jun 19;16(12). pii: E2168. doi: 10.3390/ijerph16122168.


Rey Tangled Line Test: A measure of processing speed in TBI.

Joseph AC, Peterson HA, Garcia KM, McNally SM, Mburu TK, Lippa SM, Dsurney J, Chan L.

Rehabil Psychol. 2019 Jun 27. doi: 10.1037/rep0000284. [Epub ahead of print]


Dementia-Related Functional Disability in Moderate to Advanced Parkinson's Disease: Assessment Using the World Health Organization Disability Assessment Schedule 2.0.

Chen JH, Hong CT, Wu D, Chi WC, Yen CF, Liao HF, Chan L, Liou TH.

Int J Environ Res Public Health. 2019 Jun 24;16(12). pii: E2230. doi: 10.3390/ijerph16122230.


The oncological survival and prognosis of individuals receiving PD-1 inhibitor with and without immunologic cutaneous adverse events.

Chan L, Hwang SJE, Kyaw M, Byth K, Carlino MS, Chou S, Fernandez-Penas P.

J Am Acad Dermatol. 2019 Jun 21. pii: S0190-9622(19)31024-2. doi: 10.1016/j.jaad.2019.06.035. [Epub ahead of print]


The Work Disability Functional Assessment Battery (WD-FAB).

Jette AM, Ni P, Rasch E, Marfeo E, McDonough C, Brandt D, Kazis L, Chan L.

Phys Med Rehabil Clin N Am. 2019 Aug;30(3):561-572. doi: 10.1016/j.pmr.2019.03.004. Epub 2019 May 11. Review.


Clinical Features of High-Grade Extremity and Trunk Sarcomas in Patients Aged 80 Years and Older: Why Are Outcomes Inferior?

Imanishi J, Chan LWM, Broadhead ML, Pang G, Ngan SY, Slavin J, Sharp S, Choong PFM.

Front Surg. 2019 May 31;6:29. doi: 10.3389/fsurg.2019.00029. eCollection 2019.


Position Statement on Secukinumab in the Management of Plaque Psoriasis: The Malaysian Perspective.

Johar A, Thevarajah S, Heng A, Chan LC, Ch'ng CC, Mohd Safdar NA, Muniandy P, Taib T, Tan WC, Tey KE.

Dermatol Res Pract. 2019 May 12;2019:8923168. doi: 10.1155/2019/8923168. eCollection 2019. Review.


How do you treat traumatic brain injury? One symptom at a time.

Brody DL, Chan L, Cizza G.

Ann Neurol. 2019 Sep;86(3):329-331. doi: 10.1002/ana.25529. Epub 2019 Jul 2. No abstract available.


Prognostic Factors for Combined Ranibizumab and Prompt Verteporfin Photodynamic Therapy for Polypoidal Choroidal Vasculopathy.

Hsia Y, Chan LW, Yang CH, Yang CM, Hsieh YT.

Photodiagnosis Photodyn Ther. 2019 Jun 10. pii: S1572-1000(19)30169-3. doi: 10.1016/j.pdpdt.2019.06.004. [Epub ahead of print]


Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancer.

Ho DW, Tsui YM, Sze KM, Chan LK, Cheung TT, Lee E, Sham PC, Tsui SK, Lee TK, Ng IO.

Cancer Lett. 2019 Sep 10;459:176-185. doi: 10.1016/j.canlet.2019.06.002. Epub 2019 Jun 10.


ACTH signalling and adrenal development: lessons from mouse models.

Novoselova T, King P, Guasti L, Metherell LA, Clark AJL, Chan LF.

Endocr Connect. 2019 Jun 1. pii: EC-19-0190.R1. doi: 10.1530/EC-19-0190. [Epub ahead of print] Review.


Magnetic Foreign Body Ingestion in Children: The Attractive Hazards.

Lin A, Chan LCN, Hon KLE, Tsui SYB, Pang KKY, Cheung HM, Leung AKC.

Case Rep Pediatr. 2019 Apr 28;2019:3549242. doi: 10.1155/2019/3549242. eCollection 2019.


Early biochemical predictors of survival in intermediate and high-risk prostate cancer treated with radiation and androgen deprivation therapy.

Patel MA, Kollmeier M, McBride S, Gorovets D, Varghese M, Chan L, Knezevic A, Zhang Z, Zelefsky MJ.

Radiother Oncol. 2019 Jun 6;140:34-40. doi: 10.1016/j.radonc.2019.04.003. [Epub ahead of print]


Near infrared spectroscopy for rapid and in-line detection of particle size distribution variability in lactose during mixing.

Lee WB, Widjaja E, Heng PWS, Chan LW.

Int J Pharm. 2019 Jul 20;566:454-462. doi: 10.1016/j.ijpharm.2019.06.002. Epub 2019 Jun 3.


Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa.

Lwin SM, Syed F, Di WL, Kadiyirire T, Liu L, Guy A, Petrova A, Abdul-Wahab A, Reid F, Phillips R, Elstad M, Georgiadis C, Aristodemou S, Lovell PA, McMillan JR, Mee J, Miskinyte S, Titeux M, Ozoemena L, Pramanik R, Serrano S, Rowles R, Maurin C, Orrin E, Martinez-Queipo M, Rashidghamat E, Tziotzios C, Onoufriadis A, Chen M, Chan L, Farzaneh F, Del Rio M, Tolar J, Bauer JW, Larcher F, Antoniou MN, Hovnanian A, Thrasher AJ, Mellerio JE, Qasim W, McGrath JA.

JCI Insight. 2019 Jun 6;4(11). pii: 126243. doi: 10.1172/jci.insight.126243. eCollection 2019 Jun 6.


Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression.

Hu Q, Ye Y, Chan LC, Li Y, Liang K, Lin A, Egranov SD, Zhang Y, Xia W, Gong J, Pan Y, Chatterjee SS, Yao J, Evans KW, Nguyen TK, Park PK, Liu J, Coarfa C, Donepudi SR, Putluri V, Putluri N, Sreekumar A, Ambati CR, Hawke DH, Marks JR, Gunaratne PH, Caudle AS, Sahin AA, Hortobagyi GN, Meric-Bernstam F, Chen L, Yu D, Hung MC, Curran MA, Han L, Lin C, Yang L.

Nat Immunol. 2019 Jul;20(7):835-851. doi: 10.1038/s41590-019-0400-7. Epub 2019 Jun 3.


Prevalence of cognitive impairment using the Montreal Cognitive Assessment questionnaire among patients with systemic lupus erythematosus: a cross-sectional study at two tertiary centres in Malaysia.

Kanapathy A, Nik Jaafar NR, Shaharir SS, Chan LF, Rozita M, Ch'ng SS.

Lupus. 2019 Jun;28(7):854-861. doi: 10.1177/0961203319852153. Epub 2019 Jun 4.


Ethyl acetate extract of Nepenthes adrianii x clipeata induces antiproliferation, apoptosis, and DNA damage against oral cancer cells through oxidative stress.

Tang JY, Peng SY, Cheng YB, Wang CL, Farooqi AA, Yu TJ, Hou MF, Wang SC, Yen CH, Chan LP, Ou-Yang F, Chang HW.

Environ Toxicol. 2019 Aug;34(8):891-901. doi: 10.1002/tox.22748. Epub 2019 Jun 3.


Focus Quality Assessment of High-Throughput Whole Slide Imaging in Digital Pathology.

Hosseini MS, Brawley-Hayes JAZ, Zhang Y, Chan L, Plataniotis KN, Damaskinos S.

IEEE Trans Med Imaging. 2019 May 29. doi: 10.1109/TMI.2019.2919722. [Epub ahead of print]


Stem Cell Replacement Therapies in Parkinson's Disease.

Zeng L, Chan LL, Lim EC, Tan EK.

Ann Acad Med Singapore. 2019 Apr;48(4):112-114. No abstract available.


The interaction of assembly protein AP180 and clathrin is inhibited by multi-site phospho-mimetics.

Moshkanbaryans L, Chan LS, Engholm-Keller K, Wark JR, Robinson PJ, Graham ME.

Neurochem Int. 2019 May 23;129:104474. doi: 10.1016/j.neuint.2019.104474. [Epub ahead of print]


Block of NF-kB signaling accelerates MYC-driven hepatocellular carcinogenesis and modifies the tumor phenotype towards combined hepatocellular cholangiocarcinoma.

He J, Gerstenlauer M, Chan LK, Leithäuser F, Yeh MM, Wirth T, Maier HJ.

Cancer Lett. 2019 Aug 28;458:113-122. doi: 10.1016/j.canlet.2019.05.023. Epub 2019 May 22.

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