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Plasma Amyloid Beta and Tau Levels Are Predictors of Post-stroke Cognitive Impairment: A Longitudinal Study.

Chi NF, Chao SP, Huang LK, Chan L, Chen YR, Chiou HY, Hu CJ.

Front Neurol. 2019 Jul 2;10:715. doi: 10.3389/fneur.2019.00715. eCollection 2019.


Correction to: The early identification of disease progression in patients with suspected infection presenting to the emergency department: a multi-centre derivation and validation study.

Saeed K, Wilson DC, Bloos F, Schuetz P, van der Does Y, Melander O, Hausfater P, Legramante JM, Claessens YE, Amin D, Rosenqvist M, White G, Mueller B, Limper M, Callejo CC, Brandi A, Macchi MA, Cortes N, Kutz A, Patka P, Yañez MC, Bernardini S, Beau N, Dryden M, van Gorp ECM, Minieri M, Chan L, Rood PPM, Del Castillo JG.

Crit Care. 2019 Jul 15;23(1):255. doi: 10.1186/s13054-019-2536-0.


IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion.

Chan LC, Li CW, Xia W, Hsu JM, Lee HH, Cha JH, Wang HL, Yang WH, Yen EY, Chang WC, Zha Z, Lim SO, Lai YJ, Liu C, Liu J, Dong Q, Yang Y, Sun L, Wei Y, Nie L, Hsu JL, Li H, Ye Q, Hassan MM, Amin HM, Kaseb AO, Lin X, Wang SC, Hung MC.

J Clin Invest. 2019 Jul 15;130. pii: 126022. doi: 10.1172/JCI126022. eCollection 2019 Jul 15.


Proteomic profiling in liver cancer: another new page.

Chan LK, Ng IO.

Transl Gastroenterol Hepatol. 2019 Jun 21;4:47. doi: 10.21037/tgh.2019.06.03. eCollection 2019. No abstract available.


Tris(8-Hydroxyquinoline)iron induces apoptotic cell death via oxidative stress and by activating death receptor signaling pathway in human head and neck carcinoma cells.

Chan LP, Tseng YP, Ding HY, Pan SM, Chiang FY, Wang LF, Chou TH, Lien PJ, Liu C, Kuo PL, Liang CH.

Phytomedicine. 2019 Jun 30;63:153005. doi: 10.1016/j.phymed.2019.153005. [Epub ahead of print]


Archives Seeks to Improve Abstract Reporting Quality.

Heinemann AW, Chan L, Hoenig HM.

Arch Phys Med Rehabil. 2019 Jun 15. pii: S0003-9993(19)30394-6. doi: 10.1016/j.apmr.2019.05.027. [Epub ahead of print] No abstract available.


Impact of a Probiotic Product on Bowel Habits and Microbial Profile in Subjects with Functional Constipation: A Randomized Controlled Trial.

Martoni CJ, Evans M, Chow CT, Chan LS, Leyer G.

J Dig Dis. 2019 Jul 4. doi: 10.1111/1751-2980.12797. [Epub ahead of print]


Antiparkinsonism anticholinergics increase dementia risk in patients with Parkinson's disease.

Hong CT, Chan L, Wu D, Chen WT, Chien LN.

Parkinsonism Relat Disord. 2019 Jun 25. pii: S1353-8020(19)30285-8. doi: 10.1016/j.parkreldis.2019.06.022. [Epub ahead of print]


Association between Ambulatory Status and Functional Disability in Elderly People with Dementia.

Lee HH, Hong CT, Wu D, Chi WC, Yen CF, Liao HF, Chan L, Liou TH.

Int J Environ Res Public Health. 2019 Jun 19;16(12). pii: E2168. doi: 10.3390/ijerph16122168.


Rey Tangled Line Test: A measure of processing speed in TBI.

Joseph AC, Peterson HA, Garcia KM, McNally SM, Mburu TK, Lippa SM, Dsurney J, Chan L.

Rehabil Psychol. 2019 Jun 27. doi: 10.1037/rep0000284. [Epub ahead of print]


Dementia-Related Functional Disability in Moderate to Advanced Parkinson's Disease: Assessment Using the World Health Organization Disability Assessment Schedule 2.0.

Chen JH, Hong CT, Wu D, Chi WC, Yen CF, Liao HF, Chan L, Liou TH.

Int J Environ Res Public Health. 2019 Jun 24;16(12). pii: E2230. doi: 10.3390/ijerph16122230.


The oncological survival and prognosis of individuals receiving PD-1 inhibitor with and without immunologic cutaneous adverse events.

Chan L, Hwang SJE, Kyaw M, Byth K, Carlino MS, Chou S, Fernandez-Penas P.

J Am Acad Dermatol. 2019 Jun 21. pii: S0190-9622(19)31024-2. doi: 10.1016/j.jaad.2019.06.035. [Epub ahead of print]


The Work Disability Functional Assessment Battery (WD-FAB).

Jette AM, Ni P, Rasch E, Marfeo E, McDonough C, Brandt D, Kazis L, Chan L.

Phys Med Rehabil Clin N Am. 2019 Aug;30(3):561-572. doi: 10.1016/j.pmr.2019.03.004. Epub 2019 May 11. Review.


Clinical Features of High-Grade Extremity and Trunk Sarcomas in Patients Aged 80 Years and Older: Why Are Outcomes Inferior?

Imanishi J, Chan LWM, Broadhead ML, Pang G, Ngan SY, Slavin J, Sharp S, Choong PFM.

Front Surg. 2019 May 31;6:29. doi: 10.3389/fsurg.2019.00029. eCollection 2019.


Position Statement on Secukinumab in the Management of Plaque Psoriasis: The Malaysian Perspective.

Johar A, Thevarajah S, Heng A, Chan LC, Ch'ng CC, Mohd Safdar NA, Muniandy P, Taib T, Tan WC, Tey KE.

Dermatol Res Pract. 2019 May 12;2019:8923168. doi: 10.1155/2019/8923168. eCollection 2019. Review.


How do you treat traumatic brain injury? One symptom at a time.

Brody DL, Chan L, Cizza G.

Ann Neurol. 2019 Jun 17. doi: 10.1002/ana.25529. [Epub ahead of print] No abstract available.


Prognostic Factors for Combined Ranibizumab and Prompt Verteporfin Photodynamic Therapy for Polypoidal Choroidal Vasculopathy.

Hsia Y, Chan LW, Yang CH, Yang CM, Hsieh YT.

Photodiagnosis Photodyn Ther. 2019 Jun 10. pii: S1572-1000(19)30169-3. doi: 10.1016/j.pdpdt.2019.06.004. [Epub ahead of print]


Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancer.

Ho DW, Tsui YM, Sze KM, Chan LK, Cheung TT, Lee E, Sham PC, Tsui SK, Lee TK, Ng IO.

Cancer Lett. 2019 Sep 10;459:176-185. doi: 10.1016/j.canlet.2019.06.002. Epub 2019 Jun 10.


ACTH signalling and adrenal development: lessons from mouse models.

Novoselova T, King P, Guasti L, Metherell LA, Clark AJL, Chan LF.

Endocr Connect. 2019 Jun 1. pii: EC-19-0190.R1. doi: 10.1530/EC-19-0190. [Epub ahead of print] Review.


Magnetic Foreign Body Ingestion in Children: The Attractive Hazards.

Lin A, Chan LCN, Hon KLE, Tsui SYB, Pang KKY, Cheung HM, Leung AKC.

Case Rep Pediatr. 2019 Apr 28;2019:3549242. doi: 10.1155/2019/3549242. eCollection 2019.


Early biochemical predictors of survival in intermediate and high-risk prostate cancer treated with radiation and androgen deprivation therapy.

Patel MA, Kollmeier M, McBride S, Gorovets D, Varghese M, Chan L, Knezevic A, Zhang Z, Zelefsky MJ.

Radiother Oncol. 2019 Jun 6;140:34-40. doi: 10.1016/j.radonc.2019.04.003. [Epub ahead of print]


Near infrared spectroscopy for rapid and in-line detection of particle size distribution variability in lactose during mixing.

Lee WB, Widjaja E, Heng PWS, Chan LW.

Int J Pharm. 2019 Jul 20;566:454-462. doi: 10.1016/j.ijpharm.2019.06.002. Epub 2019 Jun 3.


Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa.

Lwin SM, Syed F, Di WL, Kadiyirire T, Liu L, Guy A, Petrova A, Abdul-Wahab A, Reid F, Phillips R, Elstad M, Georgiadis C, Aristodemou S, Lovell PA, McMillan JR, Mee J, Miskinyte S, Titeux M, Ozoemena L, Pramanik R, Serrano S, Rowles R, Maurin C, Orrin E, Martinez-Queipo M, Rashidghamat E, Tziotzios C, Onoufriadis A, Chen M, Chan L, Farzaneh F, Del Rio M, Tolar J, Bauer JW, Larcher F, Antoniou MN, Hovnanian A, Thrasher AJ, Mellerio JE, Qasim W, McGrath JA.

JCI Insight. 2019 Jun 6;4(11). pii: 126243. doi: 10.1172/jci.insight.126243. eCollection 2019 Jun 6.


Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression.

Hu Q, Ye Y, Chan LC, Li Y, Liang K, Lin A, Egranov SD, Zhang Y, Xia W, Gong J, Pan Y, Chatterjee SS, Yao J, Evans KW, Nguyen TK, Park PK, Liu J, Coarfa C, Donepudi SR, Putluri V, Putluri N, Sreekumar A, Ambati CR, Hawke DH, Marks JR, Gunaratne PH, Caudle AS, Sahin AA, Hortobagyi GN, Meric-Bernstam F, Chen L, Yu D, Hung MC, Curran MA, Han L, Lin C, Yang L.

Nat Immunol. 2019 Jul;20(7):835-851. doi: 10.1038/s41590-019-0400-7. Epub 2019 Jun 3.


Prevalence of cognitive impairment using the Montreal Cognitive Assessment questionnaire among patients with systemic lupus erythematosus: a cross-sectional study at two tertiary centres in Malaysia.

Kanapathy A, Nik Jaafar NR, Shaharir SS, Chan LF, Rozita M, Ch'ng SS.

Lupus. 2019 Jun;28(7):854-861. doi: 10.1177/0961203319852153. Epub 2019 Jun 4.


Ethyl acetate extract of Nepenthes adrianii x clipeata induces antiproliferation, apoptosis, and DNA damage against oral cancer cells through oxidative stress.

Tang JY, Peng SY, Cheng YB, Wang CL, Farooqi AA, Yu TJ, Hou MF, Wang SC, Yen CH, Chan LP, Ou-Yang F, Chang HW.

Environ Toxicol. 2019 Aug;34(8):891-901. doi: 10.1002/tox.22748. Epub 2019 Jun 3.


Focus Quality Assessment of High-Throughput Whole Slide Imaging in Digital Pathology.

Hosseini MS, Brawley-Hayes JAZ, Zhang Y, Chan L, Plataniotis KN, Damaskinos S.

IEEE Trans Med Imaging. 2019 May 29. doi: 10.1109/TMI.2019.2919722. [Epub ahead of print]


Stem Cell Replacement Therapies in Parkinson's Disease.

Zeng L, Chan LL, Lim EC, Tan EK.

Ann Acad Med Singapore. 2019 Apr;48(4):112-114. No abstract available.


The interaction of assembly protein AP180 and clathrin is inhibited by multi-site phospho-mimetics.

Moshkanbaryans L, Chan LS, Engholm-Keller K, Wark JR, Robinson PJ, Graham ME.

Neurochem Int. 2019 May 23;129:104474. doi: 10.1016/j.neuint.2019.104474. [Epub ahead of print]


Block of NF-kB signaling accelerates MYC-driven hepatocellular carcinogenesis and modifies the tumor phenotype towards combined hepatocellular cholangiocarcinoma.

He J, Gerstenlauer M, Chan LK, Leithäuser F, Yeh MM, Wirth T, Maier HJ.

Cancer Lett. 2019 Aug 28;458:113-122. doi: 10.1016/j.canlet.2019.05.023. Epub 2019 May 22.


Symptom Profile of Chronic Rhinosinusitis Versus Obstructive Sleep Apnea in a Tertiary Rhinology Clinic.

Ji K, Risoli TJ, Kuchibhatla M, Chan L, Hachem RA, Jang DW.

Ann Otol Rhinol Laryngol. 2019 May 22:3489419851527. doi: 10.1177/0003489419851527. [Epub ahead of print]


Bayesian optimization for conformer generation.

Chan L, Hutchison GR, Morris GM.

J Cheminform. 2019 May 21;11(1):32. doi: 10.1186/s13321-019-0354-7.


Metformin reverses PARP inhibitors-induced epithelial-mesenchymal transition and PD-L1 upregulation in triple-negative breast cancer.

Han Y, Li CW, Hsu JM, Hsu JL, Chan LC, Tan X, He GJ.

Am J Cancer Res. 2019 Apr 1;9(4):800-815. eCollection 2019.


Tropism of influenza B viruses in human respiratory tract explants and airway organoids.

Bui CHT, Ng MMT, Cheung MC, Ng KC, Chan MPK, Chan LLY, Fong JHM, Nicholls JM, Peiris JSM, Chan RWY, Chan MCW.

Eur Respir J. 2019 May 16. pii: 1900008. doi: 10.1183/13993003.00008-2019. [Epub ahead of print]


Taxonomy and toxicity of Prorocentrum from Perhentian Islands (Malaysia), with a description of a non-toxigenic species Prorocentrum malayense sp. nov. (Dinophyceae).

Lim ZF, Luo Z, Lee LK, Hii KS, Teng ST, Chan LL, Chomérat N, Krock B, Gu H, Lim PT, Leaw CP.

Harmful Algae. 2019 Mar;83:95-108. doi: 10.1016/j.hal.2019.01.007. Epub 2019 Mar 15.


Amelioration of Endoplasmic Reticulum Stress by Mesenchymal Stem Cells Via Hepatocyte Growth Factor/c-Met Signaling in Obesity-Associated Kidney Injury.

Li B, Leung JCK, Chan LYY, Yiu WH, Li Y, Lok SWY, Liu WH, Chan KW, Tse HF, Lai KN, Tang SCW.

Stem Cells Transl Med. 2019 May 3. doi: 10.1002/sctm.18-0265. [Epub ahead of print]


Pre-clinical Safety and Efficacy of Lentiviral Vector-Mediated Ex Vivo Stem Cell Gene Therapy for the Treatment of Mucopolysaccharidosis IIIA.

Ellison SM, Liao A, Wood S, Taylor J, Youshani AS, Rowlston S, Parker H, Armant M, Biffi A, Chan L, Farzaneh F, Wynn R, Jones SA, Heal P, Gaspar HB, Bigger BW.

Mol Ther Methods Clin Dev. 2019 Apr 6;13:399-413. doi: 10.1016/j.omtm.2019.04.001. eCollection 2019 Jun 14.


Transplantation and diabetes (Transdiab): a pilot randomised controlled trial of metformin in impaired glucose tolerance after kidney transplantation.

Alnasrallah B, Goh TL, Chan LW, Manley P, Pilmore H.

BMC Nephrol. 2019 Apr 29;20(1):147. doi: 10.1186/s12882-019-1321-2.


Cardiovascular Risk Reduction with Icosapent Ethyl.

Chan LN.

N Engl J Med. 2019 Apr 25;380(17):1677. doi: 10.1056/NEJMc1902165. No abstract available.


Short Cationic Peptide Derived from Archaea with Dual Antibacterial Properties and Anti-Infective Potential.

Cândido ES, Cardoso MH, Chan LY, Torres MDT, Oshiro KGN, Porto WF, Ribeiro SM, Haney EF, Hancock REW, Lu TK, de la Fuente-Nunez C, Craik DJ, Franco OL.

ACS Infect Dis. 2019 Jul 12;5(7):1081-1086. doi: 10.1021/acsinfecdis.9b00073. Epub 2019 May 1.


Microbiota-Produced N-Formyl Peptide fMLF Promotes Obesity-Induced Glucose Intolerance.

Wollam J, Riopel M, Xu YJ, Johnson AMF, Ofrecio JM, Ying W, El Ouarrat D, Chan LS, Han AW, Mahmood NA, Ryan CN, Lee YS, Watrous JD, Chordia MD, Pan D, Jain M, Olefsky JM.

Diabetes. 2019 Jul;68(7):1415-1426. doi: 10.2337/db18-1307. Epub 2019 Apr 22.


An in vitro functional assay to measure the biological activity of TB vaccine candidate H4-IC31.

Ming M, Bernardo L, Williams K, Kolattukudy P, Kapoor N, Chan LG, Pagnon A, Piras F, Su J, Gajewska B, Salha D, Gisonni-Lex L.

Vaccine. 2019 May 16;37(22):2960-2966. doi: 10.1016/j.vaccine.2019.04.035. Epub 2019 Apr 19.


Risk assessment of the tropism & pathogenesis of the highly pathogenic avian influenza A/H7N9 virus using ex vivo & in vitro cultures of human respiratory tract.

Chan LLY, Hui KPY, Kuok DIT, Bui CHT, Ng KC, Mok CKP, Yang ZF, Guan W, Poon LLM, Zhong N, Peiris JSM, Nicholls JM, Chan MCW.

J Infect Dis. 2019 Apr 18. pii: jiz165. doi: 10.1093/infdis/jiz165. [Epub ahead of print]


Asymptomatic Prostate Cancer Brain Metastases on 68Ga-PSMA PET/CT.

Yin C, Ho B, Chan L, Emmett L.

Clin Nucl Med. 2019 Jun;44(6):e382-e384. doi: 10.1097/RLU.0000000000002548.


X-ray radiolytic labeling reveals the molecular basis of orange carotenoid protein photoprotection and its interactions with fluorescence recovery protein.

Gupta S, Sutter M, Remesh SG, Dominguez-Martin MA, Bao H, Feng XA, Chan LG, Petzold CJ, Kerfeld CA, Ralston CY.

J Biol Chem. 2019 May 31;294(22):8848-8860. doi: 10.1074/jbc.RA119.007592. Epub 2019 Apr 12.


Primary Care Provider Perceptions of Pharmacist Services in an Urban, Safety Net Health System.

McNamara A, Chan LLS, Wong SL.

J Pharm Pract. 2019 Apr 12:897190019838422. doi: 10.1177/0897190019838422. [Epub ahead of print]


Structure-Function Relationships in PMA and PMAT Series Copolymers for Polymer Solar Cells.

Chen JH, Liu CK, Chang WC, Sah PT, Chan LH.

Polymers (Basel). 2018 Apr 1;10(4). pii: E384. doi: 10.3390/polym10040384.


Conformational Dynamics of the HIV-Vif Protein Complex.

Ball KA, Chan LM, Stanley DJ, Tierney E, Thapa S, Ta HM, Burton L, Binning JM, Jacobson MP, Gross JD.

Biophys J. 2019 Apr 23;116(8):1432-1445. doi: 10.1016/j.bpj.2019.03.014. Epub 2019 Mar 23.


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