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A rapid methods development workflow for high-throughput quantitative proteomic applications.

Chen Y, Vu J, Thompson MG, Sharpless WA, Chan LJG, Gin JW, Keasling JD, Adams PD, Petzold CJ.

PLoS One. 2019 Feb 14;14(2):e0211582. doi: 10.1371/journal.pone.0211582. eCollection 2019.


The early identification of disease progression in patients with suspected infection presenting to the emergency department: a multi-centre derivation and validation study.

Saeed K, Wilson DC, Bloos F, Schuetz P, van der Does Y, Melander O, Hausfater P, Legramante JM, Claessens YE, Amin D, Rosenqvist M, White G, Mueller B, Limper M, Callejo CC, Brandi A, Macchi MA, Cortes N, Kutz A, Patka P, Yañez MC, Bernardini S, Beau N, Dryden M, van Gorp ECM, Minieri M, Chan L, Rood PPM, Del Castillo JG.

Crit Care. 2019 Feb 8;23(1):40. doi: 10.1186/s13054-019-2329-5.


Evidence for an Integrated Gene Repression Mechanism Based on mRNA Isoform Toggling in Human Cells.

Hollerer I, Barker JC, Jorgensen V, Tresenrider A, Dugast-Darzacq C, Chan LY, Darzacq X, Tjian R, Ünal E, Brar GA.

G3 (Bethesda). 2019 Feb 5. pii: g3.200802.2018. doi: 10.1534/g3.118.200802. [Epub ahead of print]


Association Between Net Vertebral Artery Flow Volume and Non-AF Stroke: A Retrospective 2-Year Analysis.

Lee HH, Huang LK, Chang HJ, Wu D, Chi NF, Chan L, Hu CJ, Chen CC.

Front Neurol. 2019 Jan 18;9:1198. doi: 10.3389/fneur.2018.01198. eCollection 2018.


Gene therapy for neuropathic pain using dorsal root ganglion-targeted helper-dependent adenoviral vectors with GAD67 expression.

Ogawa N, Terashima T, Oka K, Chan L, Kojima H.

Pain Rep. 2018 Oct 15;3(6):e695. doi: 10.1097/PR9.0000000000000695. eCollection 2018 Nov.


Discovery and Characterization of Cyclic and Acyclic Trypsin Inhibitors from Momordica dioica.

Du J, Chan LY, Poth AG, Craik DJ.

J Nat Prod. 2019 Jan 23. doi: 10.1021/acs.jnatprod.8b00716. [Epub ahead of print]


Racial trauma, microaggressions, and becoming racially innocuous: The role of acculturation and White supremacist ideology.

Liu WM, Liu RZ, Garrison YL, Kim JYC, Chan L, Ho YCS, Yeung CW.

Am Psychol. 2019 Jan;74(1):143-155. doi: 10.1037/amp0000368.


Miniaturized pH Holographic Sensors for the Monitoring of Lactobacillus casei Shirota Growth in a Microfluidic Chip.

Chan LCZ, Khalili Moghaddam G, Wang Z, Lowe CR.

ACS Sens. 2019 Jan 31. doi: 10.1021/acssensors.8b01470. [Epub ahead of print]


Diagnostic accuracy of the T-MACS decision aid with a contemporary point-of-care troponin assay.

Body R, Almashali M, Morris N, Moss P, Jarman H, Appelboam A, Parris R, Chan L, Walker A, Harrison M, Wootten A, McDowell G.

Heart. 2019 Jan 12. pii: heartjnl-2018-313825. doi: 10.1136/heartjnl-2018-313825. [Epub ahead of print]


In Pursuit of Excellence Reconsidered: Expertise and Expert Performance in the Teaching, Learning, and Application of Anatomy.

Lachman N, Chan LK, Evans DJR, Wilson TD, Pawlina W.

Anat Sci Educ. 2019 Jan;12(1):3-5. doi: 10.1002/ase.1850. No abstract available.


Left Ventricular Function Before and After Aerobic Exercise Training in Women With Pulmonary Arterial Hypertension.

Woolstenhulme JG, Guccione AA, Herrick JE, Collins JP, Nathan SD, Chan L, Keyser RE.

J Cardiopulm Rehabil Prev. 2019 Jan 7. doi: 10.1097/HCR.0000000000000397. [Epub ahead of print]


Plasma endostatin predicts kidney outcomes in patients with type 2 diabetes.

Chauhan K, Verghese DA, Rao V, Chan L, Parikh CR, Coca SG, Nadkarni GN.

Kidney Int. 2019 Feb;95(2):439-446. doi: 10.1016/j.kint.2018.09.019. Epub 2018 Dec 24.


Falls in nursing homes: challenges from a nursing perspective.

Chan DKY, Chan LKM.

Br J Community Nurs. 2019 Jan 2;24(1):6-9. doi: 10.12968/bjcn.2019.24.1.6. No abstract available.


MRI-guided adaptive brachytherapy for locally advanced cervix cancer: Treatment outcomes from a single institution in Hong Kong.

Wu PY, Wong TPW, Yip YYC, Chang TYA, Chan LKL, Lee MCH, Law LYA, Yeung MWR, Soong SI.

Brachytherapy. 2018 Dec 20. pii: S1538-4721(18)30622-6. doi: 10.1016/j.brachy.2018.11.007. [Epub ahead of print]


Psychometric Evaluation of the Improved Work-Disability Functional Assessment Battery.

Meterko M, Marino M, Ni P, Marfeo E, McDonough CM, Jette A, Peterik K, Rasch E, Brandt DE, Chan L.

Arch Phys Med Rehabil. 2018 Dec 19. pii: S0003-9993(18)31526-0. doi: 10.1016/j.apmr.2018.09.125. [Epub ahead of print]


Are the cardioprotective effects of the phytoestrogen resveratrol sex dependent?

Lieben Louis X, Raj P, Chan L, Zieroth S, Netticadan T, Wigle JT.

Can J Physiol Pharmacol. 2018 Dec 21. doi: 10.1139/cjpp-2018-0544. [Epub ahead of print]


APOBEC3B promotes hepatocarcinogenesis and metastasis through novel deaminase-independent activity.

Ma W, Ho DW, Sze KM, Tsui YM, Chan LK, Lee JM, Ng IO.

Mol Carcinog. 2018 Dec 21. doi: 10.1002/mc.22956. [Epub ahead of print]


The Wnt modulator ICG‑001 mediates the inhibition of nasopharyngeal carcinoma cell migration in vitro via the miR‑150/CD44 axis.

Chan LS, Man OY, Kwok HH, Chen L, Chan KC, Lung HL, Ngan RK, Wong RN, Lo KW, Lee AW, Tsao GS, Kahn M, Lung ML, Mak NK.

Int J Oncol. 2019 Mar;54(3):1010-1020. doi: 10.3892/ijo.2018.4664. Epub 2018 Dec 12.


Compulsory Admission in Hong Kong: Balance between Paternalism and Patient Liberty.

Siu BW, Fistein EC, Leung HW, Chan LS, Yan CK, Lai AC, Yuen KK, Ng KK.

East Asian Arch Psychiatry. 2018 Dec;28(4):122-128.


Is It Actionable? An Evaluation of the Rapid PCR-Based Blood Culture Identification Panel on the Management of Gram-Positive and Gram-Negative Blood Stream Infections.

Tseng AS, Kasule SN, Rice F, Mi L, Chan L, Seville MT, Grys TE.

Open Forum Infect Dis. 2018 Dec 11;5(12):ofy308. doi: 10.1093/ofid/ofy308. eCollection 2018 Dec.


The orphan nuclear receptor EAR-2 (NR2F6) inhibits hematopoietic cell differentiation and induces myeloid dysplasia in vivo.

Ichim CV, Dervovic DD, Chan LSA, Robertson CJ, Chesney A, Reis MD, Wells RA.

Biomark Res. 2018 Dec 7;6:36. doi: 10.1186/s40364-018-0149-4. eCollection 2018.


Lentiviral Vector Purification Using Genetically Encoded Biotin Mimic in Packaging Cell.

Mekkaoui L, Parekh F, Kotsopoulou E, Darling D, Dickson G, Cheung GW, Chan L, MacLellan-Gibson K, Mattiuzzo G, Farzaneh F, Takeuchi Y, Pule M.

Mol Ther Methods Clin Dev. 2018 Oct 23;11:155-165. doi: 10.1016/j.omtm.2018.10.008. eCollection 2018 Dec 14.


Groundwater Irrigation and Arsenic Speciation in Rice in Cambodia.

Murphy T, Phan K, Yumvihoze E, Irvine K, Wilson K, Lean D, Ty B, Poulain A, Laird B, Chan LHM.

J Health Pollut. 2018 Sep 10;8(19):180911. doi: 10.5696/2156-9614-8.19.180911. eCollection 2018 Sep.


Effects of Arsenic, Iron and Fertilizers in Soil on Rice in Cambodia.

Murphy T, Phan K, Yumvihoze E, Irvine K, Wilson K, Lean D, Poulain A, Laird B, Chan LHM.

J Health Pollut. 2018 Sep 10;8(19):180910. doi: 10.5696/2156-9614-8.19.180910. eCollection 2018 Sep.


Measuring Work Related Physical and Mental Health Function: Updating the Work Disability Functional Assessment Battery (WD-FAB) using Item Response Theory.

Marfeo EE, McDonough C, Ni P, Peterik K, Porcino J, Meterko M, Rasch E, Kazis L, Chan L.

J Occup Environ Med. 2018 Dec 11. doi: 10.1097/JOM.0000000000001521. [Epub ahead of print]


Probing the impact of HPMC viscosity grade and proportion on the physical properties of co-freeze-dried mannitol-HPMC tableting excipients using multivariate analysis methods.

Siow CRS, Tang DS, Heng PWS, Chan LW.

Int J Pharm. 2019 Feb 10;556:246-262. doi: 10.1016/j.ijpharm.2018.11.071. Epub 2018 Dec 7.


Plasma miR-1290 Is a Novel and Specific Biomarker for Early Diagnosis of Necrotizing Enterocolitis-Biomarker Discovery with Prospective Cohort Evaluation.

Ng PC, Chan KYY, Yuen TP, Sit T, Lam HS, Leung KT, Wong RPO, Chan LCN, Pang YLI, Cheung HM, Chu WCW, Li K.

J Pediatr. 2019 Feb;205:83-90.e10. doi: 10.1016/j.jpeds.2018.09.031. Epub 2018 Oct 24.


Association of Central Venous Oxygen Saturation Variability and Mortality in Hemodialysis Patients.

Zhang H, Campos I, Chan L, Meyring-Wösten A, Tapia Silva LM, Rivera Fuentes L, Preciado P, Thijssen S, Kooman JP, van der Sande FM, Kotanko P.

Blood Purif. 2018 Dec 6:1-8. doi: 10.1159/000494630. [Epub ahead of print]


Manilkara zapota (L.) P. Royen Leaf Water Extract Induces Apoptosis in Human Hepatocellular Carcinoma (HepG2) Cells via ERK1/2/Akt1/JNK1 Signaling Pathways.

Tan BL, Norhaizan ME, Chan LC.

Evid Based Complement Alternat Med. 2018 Nov 5;2018:7826576. doi: 10.1155/2018/7826576. eCollection 2018.


Serum lipid level is not associated with symptomatic intracerebral hemorrhage after intravenous thrombolysis for acute ischemic stroke.

Lin TC, Lin YK, Chen CI, Chan L, Chi NF, Yuan RY, Sheu JJ, Wei CR, Tsai JP, Yeh TH.

PeerJ. 2018 Nov 23;6:e6021. doi: 10.7717/peerj.6021. eCollection 2018.


Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate.

Cheng Z, Mugler CF, Keskin A, Hodapp S, Chan LY, Weis K, Mertins P, Regev A, Jovanovic M, Brar GA.

Mol Cell. 2019 Jan 3;73(1):36-47.e10. doi: 10.1016/j.molcel.2018.10.032. Epub 2018 Nov 29.


Palmitoylation stabilizes PD-L1 to promote breast tumor growth.

Yang Y, Hsu JM, Sun L, Chan LC, Li CW, Hsu JL, Wei Y, Xia W, Hou J, Qiu Y, Hung MC.

Cell Res. 2019 Jan;29(1):83-86. doi: 10.1038/s41422-018-0124-5. Epub 2018 Dec 4. No abstract available.


Energy requirements for ICU burn patients in whom the total body surface area affected exceeds 50 percent: a practical equation.

Chan LC, Lee MS, Ou YN, Cheng HL, Wang CH.

Asia Pac J Clin Nutr. 2018;27(6):1182-1189. doi: 10.6133/apjcn.201811_27(6).0003.


Bioconversion of cheese whey permeate into fungal oil by Mucor circinelloides.

Chan LG, Cohen JL, Ozturk G, Hennebelle M, Taha AY, L N de Moura Bell JM.

J Biol Eng. 2018 Nov 14;12:25. doi: 10.1186/s13036-018-0116-5. eCollection 2018.


A high-throughput inhibition assay to study MERS-CoV antibody interactions using image cytometry.

Rosen O, Chan LL, Abiona OM, Gough P, Wang L, Shi W, Zhang Y, Wang N, Kong WP, McLellan JS, Graham BS, Corbett KS.

J Virol Methods. 2019 Mar;265:77-83. doi: 10.1016/j.jviromet.2018.11.009. Epub 2018 Nov 20.


Designing multifunctional cancer-targeted nanosystem for magnetic resonance molecular imaging-guided theranostics of lung cancer.

Gao P, Mei C, He L, Xiao Z, Chan L, Zhang D, Shi C, Chen T, Luo L.

Drug Deliv. 2018 Nov;25(1):1811-1825. doi: 10.1080/10717544.2018.1494224.


Low Cholesterol Levels Increase Symptomatic Intracranial Hemorrhage Rates After Intravenous Thrombolysis: A Multicenter Cohort Validation Study.

Lin SF, Chao AC, Hu HH, Lin RT, Chen CH, Chan L, Lin HJ, Sun Y, Lin YY, Chen PL, Lin SK, Wei CY, Lin YT, Lee JT, Bai CH; Taiwan Thrombolytic Therapy for Acute Ischemic Stroke (TTT-AIS) Study Group.

J Atheroscler Thromb. 2018 Nov 21. doi: 10.5551/jat.46151. [Epub ahead of print]


More Frequent Nutrition Counseling Limits Weight Loss and Improves Energy Intake During Oncology Management: A Longitudinal Inpatient Study in Taiwan.

Yang YC, Lee MS, Cheng HL, Chou HY, Chan LC.

Nutr Cancer. 2018 Nov 21:1-9. doi: 10.1080/01635581.2018.1516791. [Epub ahead of print]


Cerebral Motor Functional Connectivity at the Acute Stage: An Outcome Predictor of Ischemic Stroke.

Chi NF, Ku HL, Chen DY, Tseng YC, Chen CJ, Lin YC, Hsieh YC, Chan L, Chiou HY, Hsu CY, Hu CJ.

Sci Rep. 2018 Nov 14;8(1):16803. doi: 10.1038/s41598-018-35192-y.


Is Ketamine the Future Clozapine for Depression? A Case Series and Literature Review on Maintenance Ketamine in Treatment-resistant Depression With Suicidal Behavior.

Chan LF, Eu CL, Soh SY, Maniam T, Shahidii Kadir Z, Chong BTW, Loo JL, Sharip S, Wong VCW, Loo TH, Ng YP, Kahn DA.

J Psychiatr Pract. 2018 Jul;24(4):279-291. doi: 10.1097/PRA.0000000000000316.


Sequentially Triggered Delivery System of Black Phosphorus Quantum Dots with Surface Charge-Switching Ability for Precise Tumor Radiosensitization.

Chan L, Gao P, Zhou W, Mei C, Huang Y, Yu XF, Chu PK, Chen T.

ACS Nano. 2018 Nov 12. doi: 10.1021/acsnano.8b06483. [Epub ahead of print]


Understanding the Alkylation of a Phenol by 1-(3-Chloropropyl)pyrrolidine: Evidence for the Intermediacy of an Azetidinium Ion.

Ashworth IW, Chan LC, Cox BG, McFarlane IM, Phillips AR.

J Org Chem. 2018 Nov 13. doi: 10.1021/acs.joc.8b02458. [Epub ahead of print]


Heterohexamers Formed by CcmK3 and CcmK4 Increase the Complexity of Beta Carboxysome Shells.

Sommer M, Sutter M, Gupta S, Kirst H, Turmo A, Lechno-Yossef S, Burton RL, Saechao C, Sloan NB, Cheng X, Chan LG, Petzold CJ, Fuentes-Cabrera M, Ralston CY, Kerfeld CA.

Plant Physiol. 2019 Jan;179(1):156-167. doi: 10.1104/pp.18.01190. Epub 2018 Nov 2.


Discovery and Characterization of Cyclotides from Rinorea Species.

Niyomploy P, Chan LY, Harvey PJ, Poth AG, Colgrave ML, Craik DJ.

J Nat Prod. 2018 Nov 26;81(11):2512-2520. doi: 10.1021/acs.jnatprod.8b00572. Epub 2018 Nov 2.


Evaluation of the quality of acute pain management in a pediatric surgical setting: Validation of a parent proxy modified version of the revised American Pain Society Patient Outcome Questionnaire.

Chaw S, Lo Y, Shariffuddin II, Wong J, Lee J, Leong DW, Ng KW, Chan L.

Paediatr Anaesth. 2019 Jan;29(1):68-76. doi: 10.1111/pan.13528. Epub 2018 Oct 31.


Measuring the profiles of the security needs of forensic psychiatric inpatients: Validation of the See, Think, Act Scale.

Siu BW, Au-Yeung CC, Chan AW, Chan LS, Yuen KK, Leung HW, Yan CK, Ng KK, Lai ACH, Tighe J.

Asia Pac Psychiatry. 2018 Oct 31:e12341. doi: 10.1111/appy.12341. [Epub ahead of print]


Generation and characterization of pathogenic Mab21l2(R51C) mouse model.

Tsang SW, Guo Y, Chan LH, Huang Y, Chow KL.

Genesis. 2018 Dec;56(11-12):e23261. doi: 10.1002/dvg.23261. Epub 2018 Nov 29.


Low-density lipoprotein level on admission is not associated with postintravenous thrombolysis intracranial hemorrhage in patients with acute ischemic stroke.

Hong CT, Chiu WT, Chi NF, Lai LY, Hu CJ, Hu HH, Chan L.

J Investig Med. 2018 Oct 26. pii: jim-2018-000827. doi: 10.1136/jim-2018-000827. [Epub ahead of print]


Spinal Ewing Sarcoma Metastatic to Bilateral Orbits.

Chan L, Megalla M, Kim JM, Pointdujour-Lim R.

Ophthalmic Plast Reconstr Surg. 2018 Nov/Dec;34(6):e206-e208. doi: 10.1097/IOP.0000000000001249.


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