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Items: 1 to 50 of 794

1.

Are Surrogate Endpoints Unbiased Metrics in Clinical Benefit Scores of the ASCO Value Framework?

Cheng S, Cheung MC, Jiang DM, McDonald E, Arciero VS, Ezeife DA, Rahmadian A, Chambers A, Sabarre KA, Parmar A, Chan KKW.

J Natl Compr Canc Netw. 2019 Dec;17(12):1489-1496. doi: 10.6004/jnccn.2019.7333.

PMID:
31805528
2.

Peri-Infarct Quantification by Cardiac Magnetic Resonance to Predict Outcomes in Ischemic Cardiomyopathy: Prognostic Systematic Review and Meta-Analysis.

Haghbayan H, Lougheed N, Deva DP, Chan KKW, Lima JAC, Yan AT.

Circ Cardiovasc Imaging. 2019 Nov;12(11):e009156. doi: 10.1161/CIRCIMAGING.119.009156. Epub 2019 Nov 18.

PMID:
31735067
3.

Real-world outcomes of FOLFIRINOX vs gemcitabine and nab-paclitaxel in advanced pancreatic cancer: A population-based propensity score-weighted analysis.

Chan KKW, Guo H, Cheng S, Beca JM, Redmond-Misner R, Isaranuwatchai W, Qiao L, Earle C, Berry SR, Biagi JJ, Welch S, Meyers BM, Mittmann N, Coburn N, Arias J, Schwartz D, Dai WF, Gavura S, McLeod R, Kennedy ED.

Cancer Med. 2019 Nov 13. doi: 10.1002/cam4.2705. [Epub ahead of print]

4.

Value-based pricing: Toward achieving a balance between individual and population gains in health benefits.

Parmar A, Jiao T, Saluja R, Chan KKW.

Cancer Med. 2019 Nov 11. doi: 10.1002/cam4.2694. [Epub ahead of print]

5.

Cost-effectiveness analysis of selective first-line use of biologics for unresectable RAS wild-type left-sided metastatic colorectal cancer.

Wong WWL, Zargar M, Berry SR, Ko YJ, Riesco-Martínez M, Chan KKW.

Curr Oncol. 2019 Oct;26(5):e597-e609. doi: 10.3747/co.26.4843. Epub 2019 Oct 1.

6.

Novel Use of Hydrodissection for the Insertion of Suprapubic Catheter Under Ultrasound Guidance.

Chan KKC, Speirs A.

Urology. 2019 Nov 5. pii: S0090-4295(19)30945-8. doi: 10.1016/j.urology.2019.09.041. [Epub ahead of print]

PMID:
31704457
7.

Health technology assessment methodology in metastatic renal cell carcinoma.

Parmar A, Chan KKW.

Nat Rev Urol. 2019 Nov 6. doi: 10.1038/s41585-019-0257-4. [Epub ahead of print] No abstract available.

PMID:
31695143
8.

Patterns of Care and Costs for Older Patients With Colorectal Cancer at the End of Life: Descriptive Study of the United States and Canada.

Bremner KE, Yabroff KR, Coughlan D, Liu N, Zeruto C, Warren JL, de Oliveira C, Mariotto AB, Lam C, Barrett MJ, Chan KK, Hoch JS, Krahn MD.

J Oncol Pract. 2019 Oct 24:JOP1900061. doi: 10.1200/JOP.19.00061. [Epub ahead of print]

PMID:
31647697
9.

Aberrant upregulation of PDK1 in ovarian cancer cells impairs CD8+ T cell function and survival through elevation of PD-L1.

Wang JJ, Siu MK, Jiang YX, Leung TH, Chan DW, Cheng RR, Cheung AN, Ngan HY, Chan KK.

Oncoimmunology. 2019 Sep 5;8(11):e1659092. doi: 10.1080/2162402X.2019.1659092. eCollection 2019.

PMID:
31646108
10.

Evidence, values, and funding decisions in Canadian cancer systems.

Peacock SJ, Regier DA, Raymakers AJN, Chan KKW.

Healthc Manage Forum. 2019 Nov;32(6):293-298. doi: 10.1177/0840470419870831. Epub 2019 Sep 4.

PMID:
31645144
11.

Impact of Increasing Wait Times on Overall Mortality of Chimeric Antigen Receptor T-Cell Therapy in Large B-Cell Lymphoma: A Discrete Event Simulation Model.

Tully S, Feng Z, Grindrod K, McFarlane T, Chan KKW, Wong WWL.

JCO Clin Cancer Inform. 2019 Oct;3:1-9. doi: 10.1200/CCI.19.00086.

12.

Spatial, Temporal and Genetic Dynamics Characteristics of Influenza B Viruses in China, 1973-2018.

Li X, Chan KKY, Xu B, Lu M, Xu B.

Virol Sin. 2019 Oct 21. doi: 10.1007/s12250-019-00161-w. [Epub ahead of print]

PMID:
31637629
13.

Pelvic Exenteration for Advanced Nonrectal Pelvic Malignancy.

PelvExCollaborative.

Ann Surg. 2019 Nov;270(5):899-905. doi: 10.1097/SLA.0000000000003533.

PMID:
31634184
14.

Correcting the Conclusion in a Study of Frameworks for Measurement of Absolute or Clinical Benefit-In Reply.

Saluja R, Cheung M, Chan KKW.

JAMA Oncol. 2019 Oct 17:1. doi: 10.1001/jamaoncol.2019.4132. [Epub ahead of print] No abstract available.

PMID:
31621814
15.

Eosinophilic Fasciitis Following Checkpoint Inhibitor Therapy: Four Cases and a Review of Literature.

Chan KK, Magro C, Shoushtari A, Rudin C, Rotemberg V, Rossi A, Lezcano C, Carrino J, Fernandez D, Postow MA, Apollo A, Lacouture ME, Bass AR.

Oncologist. 2019 Oct 15. pii: theoncologist.2019-0508. doi: 10.1634/theoncologist.2019-0508. [Epub ahead of print] Review.

PMID:
31615951
16.

Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma.

Chan KK, Wong ES, Wong IT, Cheung CL, Wong OG, Ngan HY, Cheung AN.

BMC Cancer. 2019 Oct 15;19(1):953. doi: 10.1186/s12885-019-6206-z.

17.

Factors associated with endocrine therapy adherence among post-menopausal women treated for early-stage breast cancer in Ontario, Canada.

Blanchette PS, Lam M, Richard L, Allen B, Shariff SZ, Vandenberg T, Pritchard KI, Chan KKW, Louie AV, Desautels D, Raphael J, Earle CC.

Breast Cancer Res Treat. 2019 Oct 1. doi: 10.1007/s10549-019-05430-6. [Epub ahead of print]

PMID:
31571072
18.

Quantitation of N6-Formyl-lysine Adduct Following Aristolochic Acid Exposure in Cells and Rat Tissues by Liquid Chromatography-Tandem Mass Spectrometry Coupled with Stable Isotope-Dilution Method.

Zhao Y, Chan CK, Chan KKJ, Chan W.

Chem Res Toxicol. 2019 Oct 21;32(10):2086-2094. doi: 10.1021/acs.chemrestox.9b00272. Epub 2019 Sep 13.

PMID:
31476867
19.

Liquid chromatography-tandem mass spectrometry analysis of aristolochic acids in soil samples collected from Serbia: Link to Balkan endemic nephropathy.

Chan CK, Chan KKJ, Pavlović NM, Chan W.

Rapid Commun Mass Spectrom. 2019 Aug 7. doi: 10.1002/rcm.8547. [Epub ahead of print]

PMID:
31392776
20.

Changing outcomes following pelvic exenteration for locally advanced and recurrent rectal cancer.

PelvEx Collaborative.

BJS Open. 2019 Mar 6;3(4):516-520. doi: 10.1002/bjs5.50153. eCollection 2019 Aug.

21.

Predictive biomarkers and tumor microenvironment in female genital melanomas: a multi-institutional study of 55 cases.

Yu Y, Tse KY, Lee HHY, Chow KL, Tsang HW, Wong RWC, Cheung ETY, Cheuk W, Lee VWK, Chan WK, Wong AST, Loong HHF, Chan KKL, Ngan HYS, Cheung ANY, Ip PPC.

Mod Pathol. 2019 Aug 5. doi: 10.1038/s41379-019-0345-2. [Epub ahead of print]

PMID:
31383965
22.

Targeting of lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases in ovarian cancer cells.

Chen RR, Yung MMH, Xuan Y, Zhan S, Leung LL, Liang RR, Leung THY, Yang H, Xu D, Sharma R, Chan KKL, Ngu SF, Ngan HYS, Chan DW.

Commun Biol. 2019 Jul 31;2:281. doi: 10.1038/s42003-019-0508-1. eCollection 2019.

23.

Reliability of Oncology Value Framework Outputs: Concordance Between Independent Research Groups.

Del Paggio JC, Cheng S, Booth CM, Cheung MC, Chan KKW.

JNCI Cancer Spectr. 2018 Dec 13;2(3):pky050. doi: 10.1093/jncics/pky050. eCollection 2018 Jul.

24.

Neuraminidase Inhibitors and Hospital Length of Stay: A Meta-analysis of Individual Participant Data to Determine Treatment Effectiveness Among Patients Hospitalized With Nonfatal 2009 Pandemic Influenza A(H1N1) Virus Infection.

Venkatesan S, Myles PR, Bolton KJ, Muthuri SG, Al Khuwaitir T, Anovadiya AP, Azziz-Baumgartner E, Bajjou T, Bassetti M, Beovic B, Bertisch B, Bonmarin I, Booy R, Borja-Aburto VH, Burgmann H, Cao B, Carratala J, Chinbayar T, Cilloniz C, Denholm JT, Dominguez SR, Duarte PAD, Dubnov-Raz G, Fanella S, Gao Z, Gérardin P, Giannella M, Gubbels S, Herberg J, Higuera Iglesias AL, Hoeger PH, Hu XY, Islam QT, Jiménez MF, Keijzers G, Khalili H, Kusznierz G, Kuzman I, Langenegger E, Lankarani KB, Leo YS, Libster RP, Linko R, Madanat F, Maltezos E, Mamun A, Manabe T, Metan G, Mickiene A, Mikić D, Mohn KGI, Oliva ME, Ozkan M, Parekh D, Paul M, Rath BA, Refaey S, Rodríguez AH, Sertogullarindan B, Skręt-Magierło J, Somer A, Talarek E, Tang JW, To K, Tran D, Uyeki TM, Vaudry W, Vidmar T, Zarogoulidis P; PRIDE Consortium Investigators , Nguyen-Van-Tam JS.

J Infect Dis. 2019 Jul 17. pii: jiz152. doi: 10.1093/infdis/jiz152. [Epub ahead of print]

PMID:
31314899
25.

Carbon Dot-functionalized Interferometric Optical Fiber Sensor for Detection of Ferric Ions in Biological Samples.

Yap SHK, Chan KK, Zhang G, Tjin SC, Yong KT.

ACS Appl Mater Interfaces. 2019 Aug 7;11(31):28546-28553. doi: 10.1021/acsami.9b08934. Epub 2019 Jul 26.

PMID:
31309830
27.

Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery.

Panwar N, Soehartono AM, Chan KK, Zeng S, Xu G, Qu J, Coquet P, Yong KT, Chen X.

Chem Rev. 2019 Aug 28;119(16):9559-9656. doi: 10.1021/acs.chemrev.9b00099. Epub 2019 Jul 9.

PMID:
31287663
28.

Palliative pelvic exenteration: A systematic review of patient-centered outcomes.

PelvEx Collaborative.

Eur J Surg Oncol. 2019 Oct;45(10):1787-1795. doi: 10.1016/j.ejso.2019.06.011. Epub 2019 Jun 14. Review.

PMID:
31255441
29.

CD71+ Population Enriched by HPV-E6 Protein Promotes Cancer Aggressiveness and Radioresistance in Cervical Cancer Cells.

Leung TH, Tang HW, Siu MK, Chan DW, Chan KK, Cheung AN, Ngan HY.

Mol Cancer Res. 2019 Sep;17(9):1867-1880. doi: 10.1158/1541-7786.MCR-19-0068. Epub 2019 Jun 24.

PMID:
31235657
30.

Impact of smoking on health system costs among cancer patients in a retrospective cohort study in Ontario, Canada.

Isaranuwatchai W, de Oliveira C, Mittmann N, Evans WKB, Peter A, Truscott R, Chan KK.

BMJ Open. 2019 Jun 21;9(6):e026022. doi: 10.1136/bmjopen-2018-026022.

31.

Hexokinase 2 Regulates Ovarian Cancer Cell Migration, Invasion and Stemness via FAK/ERK1/2/MMP9/NANOG/SOX9 Signaling Cascades.

Siu MKY, Jiang YX, Wang JJ, Leung THY, Han CY, Tsang BK, Cheung ANY, Ngan HYS, Chan KKL.

Cancers (Basel). 2019 Jun 12;11(6). pii: E813. doi: 10.3390/cancers11060813.

32.

Assessment of left ventricular function by CMR versus MUGA scans in breast cancer patients receiving trastuzumab: a prospective observational study.

Dhir V, Yan AT, Nisenbaum R, Sloninko J, Connelly KA, Barfett J, Haq R, Kirpalani A, Chan KKW, Petrella TM, Brezden-Masley C.

Int J Cardiovasc Imaging. 2019 Nov;35(11):2085-2093. doi: 10.1007/s10554-019-01648-z. Epub 2019 Jun 13.

PMID:
31197526
33.

Estimating hazard ratios from published Kaplan-Meier survival curves: A methods validation study.

Saluja R, Cheng S, Delos Santos KA, Chan KKW.

Res Synth Methods. 2019 Sep;10(3):465-475. doi: 10.1002/jrsm.1362. Epub 2019 Jun 24.

PMID:
31134735
34.

The impact of pricing strategy on the costs of oral anti-cancer drugs.

Truong J, Chan KKW, Mai H, Chambers A, Sabharwal M, Trudeau ME, Cheung MC.

Cancer Med. 2019 Jul;8(8):3770-3781. doi: 10.1002/cam4.2269. Epub 2019 May 27.

35.

Underuse of ECG monitoring in oncology patients receiving QT-interval prolonging drugs.

Pezo RC, Yan AT, Earle C, Chan KK.

Heart. 2019 Nov;105(21):1649-1655. doi: 10.1136/heartjnl-2018-314674. Epub 2019 May 25.

PMID:
31129611
37.

The economic impact of the transition from branded to generic oncology drugs.

Cheung WY, Kornelsen EA, Mittmann N, Leighl NB, Cheung M, Chan KK, Bradbury PA, Ng RCH, Chen BE, Ding K, Pater JL, Tu D, Hay AE.

Curr Oncol. 2019 Apr;26(2):89-93. doi: 10.3747/co.26.4395. Epub 2019 Apr 1.

38.

Special supplement on Canadian cancer costing research.

Peacock S, Chan KKW.

Curr Oncol. 2019 Apr;26(2):85-86. doi: 10.3747/co.26.5057. Epub 2019 Apr 1. No abstract available.

39.

Cost-effectiveness of docetaxel in high-volume hormone-sensitive metastatic prostate cancer.

Beca J, Majeed H, Chan KKW, Hotte SJ, Loblaw A, Hoch JS.

Can Urol Assoc J. 2019 Apr 26:396-403. doi: 10.5489/cuaj.5889. [Epub ahead of print]

PMID:
31039109
40.

The impact of experienced discrimination and self-stigma on sleep and health-related quality of life among individuals with mental disorders in Hong Kong.

Chan KKS, Fung WTW.

Qual Life Res. 2019 Aug;28(8):2171-2182. doi: 10.1007/s11136-019-02181-1. Epub 2019 Apr 16.

PMID:
30993603
41.

Author Correction: A randomized controlled trial of an ambulatory approach versus the hospital-based approach in managing suspected obstructive sleep apnea syndrome.

Hui DS, Ng SS, To KW, Ko FW, Ngai J, Chan KKP, Yip WH, Chan TO, Yiu K, Tam WWS.

Sci Rep. 2019 Apr 2;9(1):5595. doi: 10.1038/s41598-019-41389-6.

42.

A spatialized digital database for all bird species in China.

Dai S, Feng D, Chan KKY, Gong P, Xu B.

Sci China Life Sci. 2019 May;62(5):661-667. doi: 10.1007/s11427-018-9419-2. Epub 2019 Mar 12.

PMID:
30900164
43.

Ambulatory Toxicity Management (AToM) Pilot: results of a pilot study of a pro-active, telephone-based intervention to improve toxicity management during chemotherapy for breast cancer.

Krzyzanowska MK, MacKay C, Han H, Eberg M, Gandhi S, Laferriere NB, Powis M, Howell D, Atzema CL, Chan KKW, Kukreti V, Mitchell S, Nayer M, Pasetka M, Knittel-Keren D, Redwood E.

Pilot Feasibility Stud. 2019 Mar 8;5:39. doi: 10.1186/s40814-019-0404-y. eCollection 2019.

44.

Conditional approval of cancer drugs in Canada: accountability and impact on public funding.

Andersen SK, Penner N, Chambers A, Trudeau ME, Chan KKW, Cheung MC.

Curr Oncol. 2019 Feb;26(1):e100-e105. doi: 10.3747/co.26.4397. Epub 2019 Feb 1.

45.

Anticancer drugs approved by the Food and Drug Administration for gastrointestinal malignancies: Clinical benefit and price considerations.

Jiang DM, Chan KKW, Jang RW, Booth C, Liu G, Amir E, Mason R, Everest L, Elimova E.

Cancer Med. 2019 Apr;8(4):1584-1593. doi: 10.1002/cam4.2058. Epub 2019 Mar 7.

46.

Deregulated GATA6 modulates stem cell-like properties and metabolic phenotype in hepatocellular carcinoma.

Tan HW, Leung CO, Chan KK, Ho DW, Leung MS, Wong CM, Ng IO, Lo RC.

Int J Cancer. 2019 Oct 1;145(7):1860-1873. doi: 10.1002/ijc.32248. Epub 2019 Mar 28.

PMID:
30834518
47.

Thrombolysis in Myocardial Infarction Risk Score for Secondary Prevention of Recurrent Cardiovascular Events in a Real-World Cohort of Post-Acute Myocardial Infarction Patients.

Huang D, Cheng YY, Wong YA, Yung SA, Tam CF, Chan KK, Lam CS, Yiu KH, Hai JJ, Lau CP, Chan EW, Chiang CE, Wong KL, Cheung T, Cheung BM, Feng YQ, Tan N, Chen JY, Yue WS, Hu HX, Chen L, Tse HF, Chan PH, Siu CW.

Circ J. 2019 Mar 25;83(4):809-817. doi: 10.1253/circj.CJ-18-0308. Epub 2019 Feb 22.

48.

Use of Berlin questionnaire in comparison to polysomnography and home sleep study in patients with obstructive sleep apnea.

Ng SS, Tam W, Chan TO, To KW, Ngai J, Chan KKP, Yip WH, Lo RL, Yiu K, Ko FW, Hui DS.

Respir Res. 2019 Feb 22;20(1):40. doi: 10.1186/s12931-019-1009-y.

49.

A maximum curvature method for estimating epidemic onset of seasonal influenza in Japan.

Cai J, Zhang B, Xu B, Chan KKY, Chowell G, Tian H, Xu B.

BMC Infect Dis. 2019 Feb 20;19(1):181. doi: 10.1186/s12879-019-3777-x.

50.

Effects of mother-offspring and father-offspring dynamics on emerging adults' adjustment: The mediating role of emotion regulation.

Cheung RYM, Leung MC, Chan KKS, Lam CB.

PLoS One. 2019 Feb 13;14(2):e0212331. doi: 10.1371/journal.pone.0212331. eCollection 2019.

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