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Recent advances in microfluidic methods in cancer liquid biopsy.

Iliescu FS, Poenar DP, Yu F, Ni M, Chan KH, Cima I, Taylor HK, Cima I, Iliescu C.

Biomicrofluidics. 2019 Jul 23;13(4):041503. doi: 10.1063/1.5087690. eCollection 2019 Jul. Review.


Parental perspectives on decision-making about hypospadias surgery.

Chan KH, Panoch J, Carroll A, Wiehe S, Downs S, Cain MP, Frankel R.

J Pediatr Urol. 2019 May 2. pii: S1477-5131(19)30089-0. doi: 10.1016/j.jpurol.2019.04.017. [Epub ahead of print]


Image-Guided Ablation of Dental Calculus From Root Surfaces Using a DPSS Er:YAG Laser.

Fried WA, Chan KH, Darling CL, Curtis DA, Fried D.

Lasers Surg Med. 2019 Jun 24. doi: 10.1002/lsm.23122. [Epub ahead of print]


Community engagement of adolescents in the development of a patient-centered outcome tool for adolescents with a history of hypospadias repair.

Chan KH, Panoch J, Carroll A, Downs S, Cain MP, Frankel R, Cockrum B, Moore C, Wiehe S.

J Pediatr Urol. 2019 Apr 27. pii: S1477-5131(19)30083-X. doi: 10.1016/j.jpurol.2019.04.011. [Epub ahead of print]


Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling pathway.

Jian M, Kwan JS, Bunting M, Ng RC, Chan KH.

J Neuroinflammation. 2019 May 25;16(1):110. doi: 10.1186/s12974-019-1492-6.



Chan KH.

Urology. 2019 Jun;128:77. doi: 10.1016/j.urology.2019.01.047. No abstract available.


SMRT sequencing revealed the diversity and characteristics of defective interfering RNAs in influenza A (H7N9) virus infection.

Lui WY, Yuen CK, Li C, Wong WM, Lui PY, Lin CH, Chan KH, Zhao H, Chen H, To KKW, Zhang AJX, Yuen KY, Kok KH.

Emerg Microbes Infect. 2019;8(1):662-674. doi: 10.1080/22221751.2019.1611346.


Correction to "3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation".

Testa A, Lucas X, Castro GV, Chan KH, Wright JE, Runcie AC, Gadd MS, Harrison WTA, Ko EJ, Fletcher D, Ciulli A.

J Am Chem Soc. 2019 May 8;141(18):7644. doi: 10.1021/jacs.9b03833. Epub 2019 Apr 24. No abstract available.


A2ML1 and otitis media: novel variants, differential expression and relevant pathways.

Larson ED, Magno JPM, Steritz MJ, Llanes EGDV, Cardwell J, Pedro M, Roberts TB, Einarsdottir E, Rosanes RAQ, Greenlee C, Santos RAP, Yousaf A, Streubel SO, Santos ATR, Ruiz AG, Lagrana-Villagracia SM, Ray D, Yarza TKL, Scholes MA, Anderson CB, Acharya A; University of Washington Center for Mendelian Genomics, Gubbels SP, Bamshad MJ, Cass SP, Lee NR, Shaikh RS, Nickerson DA, Mohlke KL, Prager JD, Cruz TLG, Yoon PJ, Abes GT, Schwartz DA, Chan AL, Wine TM, Cutiongco-de la Paz EM, Friedman N, Kechris K, Kere J, Leal SM, Yang IV, Patel JA, Tantoco MLC, Riazuddin S, Chan KH, Mattila PS, Reyes-Quintos MRT, Ahmed ZM, Jenkins HA, Chonmaitree T, Hafrén L, Chiong CM, Santos-Cortez RLP.

Hum Mutat. 2019 Apr 22. doi: 10.1002/humu.23769. [Epub ahead of print]


Image guided laser ablation of demineralization from root surfaces.

Dhillon N, Chan KH, Yang VB, Fried D.

Proc SPIE Int Soc Opt Eng. 2019 Feb;10857. pii: 108570N. doi: 10.1117/12.2512938. Epub 2019 Feb 28.


Respiratory virus infection among hospitalized adult patients with or without clinically apparent respiratory infection: a prospective cohort study.

To KKW, Chan KH, Ho J, Pang PKP, Ho DTY, Chang ACH, Seng CW, Yip CCY, Cheng VCC, Hung IFN, Yuen KY.

Clin Microbiol Infect. 2019 Apr 18. pii: S1198-743X(19)30183-1. doi: 10.1016/j.cmi.2019.04.012. [Epub ahead of print]


Selective removal of dental calculus with a diode-pumped Er:YAG laser.

Fried WA, Chan KH, Darling CL, Fried D.

Proc SPIE Int Soc Opt Eng. 2019 Feb;10857. pii: 108570M. doi: 10.1117/12.2512937. Epub 2019 Feb 28.


Prevalence of Postconcussion Syndrome after Mild Traumatic Brain Injury in Young Adults from a Single Neurosurgical Center in East Coast of Malaysia.

Balakrishnan B, Rus RM, Chan KH, Martin AG, Awang MS.

Asian J Neurosurg. 2019 Jan-Mar;14(1):201-205. doi: 10.4103/ajns.AJNS_49_18.


The contrast of demineralization on tooth occlusal surfaces from 405 to 1950-nm with varying depth.

Mohajerani N, Chan KH, Yang VB, Fried D, Darling CL.

Proc SPIE Int Soc Opt Eng. 2019 Feb;10857. pii: 108570O. doi: 10.1117/12.2512941. Epub 2019 Feb 28.


Health Economic Analysis of Rivaroxaban and Warfarin for Venous Thromboembolism Management in Chinese Patients.

Fung KP, Chan KH, Ng V, Tsui PT, You JHS.

Cardiovasc Drugs Ther. 2019 Jun;33(3):331-337. doi: 10.1007/s10557-019-06872-2.


Catheter Ablation for Atrial Fibrillation in Heart Failure: Ready for Mainstream Adoption, or Is More Evidence Needed?

Moore BM, Chan KH, Sy RW.

Heart Lung Circ. 2019 May;28(5):665-666. doi: 10.1016/j.hlc.2019.02.006. Epub 2019 Feb 25. No abstract available.


Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection.

Liu L, Wei Q, Lin Q, Fang J, Wang H, Kwok H, Tang H, Nishiura K, Peng J, Tan Z, Wu T, Cheung KW, Chan KH, Alvarez X, Qin C, Lackner A, Perlman S, Yuen KY, Chen Z.

JCI Insight. 2019 Feb 21;4(4). pii: 123158. doi: 10.1172/jci.insight.123158. eCollection 2019 Feb 21.


Cost-Effectiveness Analysis of the Management of Distal Ureteral Stones in Children.

Chan KH, Whittam BM, Krambeck A, Downs SM, Misseri R, Cain MP, Bennett WE.

Urology. 2019 May;127:107-112. doi: 10.1016/j.urology.2019.02.007. Epub 2019 Feb 18.


Effects of foot progression angle adjustment on external knee adduction moment and knee adduction angular impulse during stair ascent and descent.

Wang S, Chan KHC, Lam RHM, Yuen DNS, Fan CKM, Chu TTC, Baur H, Cheung RTH.

Hum Mov Sci. 2019 Apr;64:213-220. doi: 10.1016/j.humov.2019.02.004. Epub 2019 Feb 20.


Large-scale otoscopic and audiometric population assessment: A pilot study.

Chan KH, Dreith S, Uhler KM, Tallo V, Lucero M, De Jesus J, Simões EA.

Int J Pediatr Otorhinolaryngol. 2019 Feb;117:148-152. doi: 10.1016/j.ijporl.2018.11.033. Epub 2018 Nov 30.


The Contemporary Era of Sudden Cardiac Death and Ventricular Arrhythmias: Basic Concepts, Recent Developments and Future Directions.

Haqqani HM, Chan KH, Kumar S, Denniss AR, Gregory AT.

Heart Lung Circ. 2019 Jan;28(1):1-5. doi: 10.1016/S1443-9506(18)31972-3. No abstract available.


Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins.

Lau SKP, Fan RYY, Luk HKH, Zhu L, Fung J, Li KSM, Wong EYM, Ahmed SS, Chan JFW, Kok RKH, Chan KH, Wernery U, Yuen KY, Woo PCY.

Emerg Microbes Infect. 2018 Dec 10;7(1):209. doi: 10.1038/s41426-018-0208-9.


Optic neuritis as the initial clinical presentation of limbic encephalitis: a case report.

Cheung SSL, Lau GKK, Chan KH, Wong IYH, Lai JSM, Tang WK, Shih KC.

J Med Case Rep. 2018 Dec 3;12(1):357. doi: 10.1186/s13256-018-1893-7.


Catheter Ablation of Post-Infarct VT: Mechanisms, Strategies and Outcomes.

Emami M, Morton JB, Chan KH, Roberts-Thomson KC.

Heart Lung Circ. 2019 Jan;28(1):76-83. doi: 10.1016/j.hlc.2018.10.003. Epub 2018 Oct 15. Review.


Initial collection of an inadequate 24-hour urine sample in children does not predict subsequent inadequate collections.

Chan KH, Moser EA, Whittam BM, Misseri R, Cain MP, Krambeck A, Schwaderer A.

J Pediatr Urol. 2019 Feb;15(1):74.e1-74.e7. doi: 10.1016/j.jpurol.2018.10.019. Epub 2018 Oct 28.


C-Terminal Residue of Ultrashort Peptides Impacts on Molecular Self-Assembly, Hydrogelation, and Interaction with Small-Molecule Drugs.

Chan KH, Lee WH, Ni M, Loo Y, Hauser CAE.

Sci Rep. 2018 Nov 20;8(1):17127. doi: 10.1038/s41598-018-35431-2.


Clinical outcomes one year and beyond after combination sirolimus eluting endothelial progenitor cell capture stenting during primary percutaneous coronary intervention in ST-segment elevation myocardial infarction.

Sim HW, Thong EH, Tan HC, Low AF, Lee CH, Chan MY, Tay EL, Loh PH, Chan KH, Loh JP.

Cardiovasc Revasc Med. 2018 Nov 7. pii: S1553-8389(18)30493-7. doi: 10.1016/j.carrev.2018.11.004. [Epub ahead of print]


FUT2 Variants Confer Susceptibility to Familial Otitis Media.

Santos-Cortez RLP, Chiong CM, Frank DN, Ryan AF, Giese APJ, Bootpetch Roberts T, Daly KA, Steritz MJ, Szeremeta W, Pedro M, Pine H, Yarza TKL, Scholes MA, Llanes EGDV, Yousaf S, Friedman N, Tantoco MLC, Wine TM, Labra PJ, Benoit J, Ruiz AG, de la Cruz RAR, Greenlee C, Yousaf A, Cardwell J, Nonato RMA, Ray D, Ong KMC, So E, Robertson CE, Dinwiddie J, Lagrana-Villagracia SM; University of Washington Center for Mendelian Genomics (UWCMG), Gubbels SP, Shaikh RS, Cass SP, Einarsdottir E, Lee NR, Schwartz DA, Gloria-Cruz TLI, Bamshad MJ, Yang IV, Kere J, Abes GT, Prager JD, Riazuddin S, Chan AL, Yoon PJ, Nickerson DA, Cutiongco-de la Paz EM, Streubel SO, Reyes-Quintos MRT, Jenkins HA, Mattila P, Chan KH, Mohlke KL, Leal SM, Hafrén L, Chonmaitree T, Sale MM, Ahmed ZM.

Am J Hum Genet. 2018 Nov 1;103(5):679-690. doi: 10.1016/j.ajhg.2018.09.010. Epub 2018 Oct 25.


Effects of 4-Week Creatine Supplementation Combined with Complex Training on Muscle Damage and Sport Performance.

Wang CC, Fang CC, Lee YH, Yang MT, Chan KH.

Nutrients. 2018 Nov 2;10(11). pii: E1640. doi: 10.3390/nu10111640.


Sudden Cardiac Death and Ventricular Arrhythmias in Hypertrophic Cardiomyopathy.

Moore B, Semsarian C, Chan KH, Sy RW.

Heart Lung Circ. 2019 Jan;28(1):146-154. doi: 10.1016/j.hlc.2018.07.019. Epub 2018 Sep 24. Review.


Generalizing polygenic risk scores from Europeans to Hispanics/Latinos.

Grinde KE, Qi Q, Thornton TA, Liu S, Shadyab AH, Chan KHK, Reiner AP, Sofer T.

Genet Epidemiol. 2019 Feb;43(1):50-62. doi: 10.1002/gepi.22166. Epub 2018 Oct 15.


Ten-year risk prediction models of complications and mortality of Chinese patients with diabetes mellitus in primary care in Hong Kong: a study protocol.

Wan EYF, Yu EYT, Chin WY, Fung CSC, Kwok RLP, Chao DVK, Chan KH, Hui EM, Tsui WWS, Tan KCB, Fong DYT, Lam CLK.

BMJ Open. 2018 Oct 15;8(10):e023070. doi: 10.1136/bmjopen-2018-023070.


Use of a DPSS Er:YAG laser for the selective removal of composite from tooth surfaces.

Fried WA, Chan KH, Darling CL, Fried D.

Biomed Opt Express. 2018 Sep 27;9(10):5026-5036. doi: 10.1364/BOE.9.005026. eCollection 2018 Oct 1.


A wobbling tachycardia: What is the mechanism?

Moore BM, Sy RW, Chan KH.

Heart Rhythm. 2018 Oct;15(10):1583-1584. doi: 10.1016/j.hrthm.2018.06.015. No abstract available.


Comparative evaluation of a laboratory-developed real-time PCR assay and RealStar® Adenovirus PCR Kit for quantitative detection of human adenovirus.

Wong SSY, Yip CCY, Sridhar S, Leung KH, Cheng AKW, Fung AMY, Lam HY, Chan KH, Chan JFW, Cheng VCC, Tang BSF, Yuen KY.

Virol J. 2018 Sep 27;15(1):149. doi: 10.1186/s12985-018-1059-7.


Solid Fuel Use and Risks of Respiratory Diseases. A Cohort Study of 280,000 Chinese Never-Smokers.

Chan KH, Kurmi OP, Bennett DA, Yang L, Chen Y, Tan Y, Pei P, Zhong X, Chen J, Zhang J, Kan H, Peto R, Lam KBH, Chen Z; China Kadoorie Biobank Collaborative Group.

Am J Respir Crit Care Med. 2019 Feb 1;199(3):352-361. doi: 10.1164/rccm.201803-0432OC.


Influenza-like illness and viral aetiology in Hong Kong children.

Cowling BJ, Chan KH, Peiris JS.

Hong Kong Med J. 2018 Oct;24 Suppl 6(5):12-15. No abstract available.


Switching to peginterferon for chronic hepatitis B patients with hepatitis B e antigen seroconversion on entecavir - A prospective study.

Chan HLY, Chan FWS, Hui AJ, Li MKK, Chan KH, Wong GLH, Loo CK, Chim AML, Tse CH, Wong VWS.

J Viral Hepat. 2019 Jan;26(1):126-135. doi: 10.1111/jvh.13000. Epub 2018 Oct 18.


The clinical, biochemical, and ultrasonographic characteristics of patients with hidradenitis suppurativa in Northern Peninsular Malaysia: a multicenter study.

Loo CH, Tan WC, Tang JJ, Khor YH, Manikam MT, Low DE, Chan KH, Chan KH, Teoh YM, Sohot NQA, Tang MM, Chan LC.

Int J Dermatol. 2018 Dec;57(12):1454-1463. doi: 10.1111/ijd.14210. Epub 2018 Sep 4.


The ability of a limited metabolic assessment to identify pediatric stone formers with metabolic abnormalities.

Chan KH, Moser EA, Whittam BM, Misseri R, Cain MP, Krambeck A.

J Pediatr Urol. 2018 Aug;14(4):331.e1-331.e6. doi: 10.1016/j.jpurol.2018.08.005. Epub 2018 Aug 7.


Significant Medical and Surgical Morbidity in Perianal Crohn's Disease: Results from a Territory-Wide Study.

Mak WY, Mak OS, Lee CK, Tang W, Leung WK, Wong MTL, Sze ASF, Li M, Leung CM, Lo FH, Lam BCY, Chan KH, Shan EHS, Tsang SWC, Hui AJ, Chow WH, Chan FKL, Sung JJY, Ng SC.

J Crohns Colitis. 2018 Nov 28;12(12):1392-1398. doi: 10.1093/ecco-jcc/jjy120.


Human tryptophanyl-tRNA synthetase is an IFN-γ-inducible entry factor for Enterovirus.

Yeung ML, Jia L, Yip CCY, Chan JFW, Teng JLL, Chan KH, Cai JP, Zhang C, Zhang AJ, Wong WM, Kok KH, Lau SKP, Woo PCY, Lo JYC, Jin DY, Shih SR, Yuen KY.

J Clin Invest. 2018 Nov 1;128(11):5163-5177. doi: 10.1172/JCI99411. Epub 2018 Oct 15.


In-built thermo-mechanical cooperative feedback mechanism for self-propelled multimodal locomotion and electricity generation.

Wang XQ, Tan CF, Chan KH, Lu X, Zhu L, Kim SW, Ho GW.

Nat Commun. 2018 Aug 24;9(1):3438. doi: 10.1038/s41467-018-06011-9.


Development and validation of a tool to identify barriers to starting insulin treatment in patients with type-2 diabetes mellitus.

Fu SN, Chin WY, Wong CK, Yeung VT, Yiu MP, Tsui HY, Chan KH.

Hong Kong Med J. 2018 Aug;24 Suppl 4(4):24-29. No abstract available.


Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016.

So RT, Perera RA, Oladipo JO, Chu DK, Kuranga SA, Chan KH, Lau EH, Cheng SM, Poon LL, Webby RJ, Peiris M.

Euro Surveill. 2018 Aug;23(32). doi: 10.2807/1560-7917.ES.2018.23.32.1800175.


Author Reply.

Chan KH, Shah A, Moser EA, Szymanski K, Whittam BM, Misseri R, Kaefer M, Rink R, Cain MP.

Urology. 2018 Aug;118:170-171. doi: 10.1016/j.urology.2017.08.065. No abstract available.


National Heart Foundation of Australia and the Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the Diagnosis and Management of Atrial Fibrillation 2018.

NHFA CSANZ Atrial Fibrillation Guideline Working Group, Brieger D, Amerena J, Attia J, Bajorek B, Chan KH, Connell C, Freedman B, Ferguson C, Hall T, Haqqani H, Hendriks J, Hespe C, Hung J, Kalman JM, Sanders P, Worthington J, Yan TD, Zwar N.

Heart Lung Circ. 2018 Oct;27(10):1209-1266. doi: 10.1016/j.hlc.2018.06.1043. No abstract available.


Dornase Alfa Ototoxic Effects in Animals and Efficacy in the Treatment of Clogged Tympanostomy Tubes in Children: A Preclinical Study and a Randomized Clinical Trial.

Chan KH, Allen GC, Kelley PE, Streubel SO, Friedman NR, Yoon P, Gao D, Ruiz AG, Jung TTK.

JAMA Otolaryngol Head Neck Surg. 2018 Sep 1;144(9):776-780. doi: 10.1001/jamaoto.2018.1101.


National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian clinical guidelines for the diagnosis and management of atrial fibrillation 2018.

Brieger D, Amerena J, Attia JR, Bajorek B, Chan KH, Connell C, Freedman B, Ferguson C, Hall T, Haqqani HM, Hendriks J, Hespe CM, Hung J, Kalman JM, Sanders P, Worthington J, Yan T, Zwar NA.

Med J Aust. 2018 Oct 15;209(8):356-362. Epub 2018 Aug 2.


Selective Ablation of Carious Lesions using an Integrated Near-IR Imaging System and a Novel 9.3-µm CO2 Laser.

Chan KH, Fried NM, Fried D.

Proc SPIE Int Soc Opt Eng. 2018 Feb;10473. pii: 104730E. doi: 10.1117/12.2296025.

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