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Items: 1 to 50 of 214

1.

Competing endogenous RNA network profiling reveals novel host dependency factors required for MERS-CoV propagation.

Zhang X, Chu H, Wen L, Shuai H, Yang D, Wang Y, Hou Y, Zhu Z, Yuan S, Yin F, Chan JF, Yuen KY.

Emerg Microbes Infect. 2020 Dec;9(1):733-746. doi: 10.1080/22221751.2020.1738277.

2.

Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility.

Chan JF, Zhang AJ, Yuan S, Poon VK, Chan CC, Lee AC, Chan WM, Fan Z, Tsoi HW, Wen L, Liang R, Cao J, Chen Y, Tang K, Luo C, Cai JP, Kok KH, Chu H, Chan KH, Sridhar S, Chen Z, Chen H, To KK, Yuen KY.

Clin Infect Dis. 2020 Mar 26. pii: ciaa325. doi: 10.1093/cid/ciaa325. [Epub ahead of print]

PMID:
32215622
3.

Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study.

To KK, Tsang OT, Leung WS, Tam AR, Wu TC, Lung DC, Yip CC, Cai JP, Chan JM, Chik TS, Lau DP, Choi CY, Chen LL, Chan WM, Chan KH, Ip JD, Ng AC, Poon RW, Luo CT, Cheng VC, Chan JF, Hung IF, Chen Z, Chen H, Yuen KY.

Lancet Infect Dis. 2020 Mar 23. pii: S1473-3099(20)30196-1. doi: 10.1016/S1473-3099(20)30196-1. [Epub ahead of print]

PMID:
32213337
4.

Improved molecular diagnosis of COVID-19 by the novel, highly sensitive and specific COVID-19-RdRp/Hel real-time reverse transcription-polymerase chain reaction assay validated in vitro and with clinical specimens.

Chan JF, Yip CC, To KK, Tang TH, Wong SC, Leung KH, Fung AY, Ng AC, Zou Z, Tsoi HW, Choi GK, Tam AR, Cheng VC, Chan KH, Tsang OT, Yuen KY.

J Clin Microbiol. 2020 Mar 4. pii: JCM.00310-20. doi: 10.1128/JCM.00310-20. [Epub ahead of print]

PMID:
32132196
5.

Escalating infection control response to the rapidly evolving epidemiology of the coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in Hong Kong.

Cheng VCC, Wong SC, Chen JHK, Yip CCY, Chuang VWM, Tsang OTY, Sridhar S, Chan JFW, Ho PL, Yuen KY.

Infect Control Hosp Epidemiol. 2020 Mar 5:1-6. doi: 10.1017/ice.2020.58. [Epub ahead of print]

PMID:
32131908
6.

Consistent detection of 2019 novel coronavirus in saliva.

To KK, Tsang OT, Chik-Yan Yip C, Chan KH, Wu TC, Chan JMC, Leung WS, Chik TS, Choi CY, Kandamby DH, Lung DC, Tam AR, Poon RW, Fung AY, Hung IF, Cheng VC, Chan JF, Yuen KY.

Clin Infect Dis. 2020 Feb 12. pii: ciaa149. doi: 10.1093/cid/ciaa149. [Epub ahead of print]

7.

Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan.

Chan JF, Kok KH, Zhu Z, Chu H, To KK, Yuan S, Yuen KY.

Emerg Microbes Infect. 2020 Jan 28;9(1):221-236. doi: 10.1080/22221751.2020.1719902. eCollection 2020. Erratum in: Emerg Microbes Infect. 2020 Dec;9(1):540.

8.

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.

Chan JF, Yuan S, Kok KH, To KK, Chu H, Yang J, Xing F, Liu J, Yip CC, Poon RW, Tsoi HW, Lo SK, Chan KH, Poon VK, Chan WM, Ip JD, Cai JP, Cheng VC, Chen H, Hui CK, Yuen KY.

Lancet. 2020 Feb 15;395(10223):514-523. doi: 10.1016/S0140-6736(20)30154-9. Epub 2020 Jan 24.

9.

Transmission of rat hepatitis E virus infection to humans in Hong Kong: a clinical and epidemiological analysis.

Sridhar S, Yip CC, Wu S, Chew NF, Leung KH, Chan JF, Zhao PS, Chan WM, Poon RW, Tsoi HW, Cai JP, Chan HS, Leung AW, Tse CW, Zee JS, Tsang OT, Cheng VC, Lau SK, Woo PC, Tsang DN, Yuen KY.

Hepatology. 2020 Jan 20. doi: 10.1002/hep.31138. [Epub ahead of print]

PMID:
31960460
10.

Identification of a Novel Ichthyic Parvovirus in Marine Species in Hainan Island, China.

Du J, Wang W, Chan JF, Wang G, Huang Y, Yi Y, Zhu Z, Peng R, Hu X, Wu Y, Zeng J, Zheng J, Cui X, Niu L, Zhao W, Lu G, Yuen KY, Yin F.

Front Microbiol. 2019 Dec 5;10:2815. doi: 10.3389/fmicb.2019.02815. eCollection 2019.

11.

Lipidomic Profiling Reveals Significant Perturbations of Intracellular Lipid Homeostasis in Enterovirus-Infected Cells.

Yan B, Zou Z, Chu H, Chan G, Tsang JO, Lai PM, Yuan S, Yip CC, Yin F, Kao RY, Sze KH, Lau SK, Chan JF, Yuen KY.

Int J Mol Sci. 2019 Nov 26;20(23). pii: E5952. doi: 10.3390/ijms20235952.

12.

Evaluation of RealStar® Alpha Herpesvirus PCR Kit for Detection of HSV-1, HSV-2, and VZV in Clinical Specimens.

Yip CCY, Sridhar S, Leung KH, Cheng AKW, Chan KH, Chan JFW, Cheng VCC, Yuen KY.

Biomed Res Int. 2019 Oct 9;2019:5715180. doi: 10.1155/2019/5715180. eCollection 2019.

13.

Epidemiological and Clinical Characteristics of Human Hepegivirus 1 Infection in Patients With Hepatitis C.

Sridhar S, Yip CCY, Chew NFS, Wu S, Leung KH, Chan JFW, Cheng VCC, Yuen KY.

Open Forum Infect Dis. 2019 Jul 12;6(8):ofz329. doi: 10.1093/ofid/ofz329. eCollection 2019 Aug.

14.

Identification of a Novel Betacoronavirus (Merbecovirus) in Amur Hedgehogs from China.

Lau SKP, Luk HKH, Wong ACP, Fan RYY, Lam CSF, Li KSM, Ahmed SS, Chow FWN, Cai JP, Zhu X, Chan JFW, Lau TCK, Cao K, Li M, Woo PCY, Yuen KY.

Viruses. 2019 Oct 24;11(11). pii: E980. doi: 10.3390/v11110980.

15.

Genotyping of Enterocytozoon bieneusi among captive long-tailed macaques (Macaca fascicularis) in Hainan Province: High genetic diversity and zoonotic potential.

Zhao W, Zhou H, Jin H, Sun L, Li P, Liu M, Qiu M, Xu L, Li F, Ma T, Wang S, Yin F, Li L, Cui X, Chan JF, Lu G.

Acta Trop. 2020 Jan;201:105211. doi: 10.1016/j.actatropica.2019.105211. Epub 2019 Oct 7.

PMID:
31600522
16.

Activation of C-Type Lectin Receptor and (RIG)-I-Like Receptors Contributes to Proinflammatory Response in Middle East Respiratory Syndrome Coronavirus-Infected Macrophages.

Zhao X, Chu H, Wong BH, Chiu MC, Wang D, Li C, Liu X, Yang D, Poon VK, Cai J, Chan JF, To KK, Zhou J, Yuen KY.

J Infect Dis. 2020 Feb 3;221(4):647-659. doi: 10.1093/infdis/jiz483.

17.

Nosocomial transmission of chickenpox and varicella zoster virus seroprevalence rate amongst healthcare workers in a teaching hospital in China.

Yang J, Liu J, Xing F, Ye H, Dai G, Liu M, Lo SK, Lau RW, Chiu KH, Chan JF, Yuen KY.

BMC Infect Dis. 2019 Jul 5;19(1):582. doi: 10.1186/s12879-019-4222-x.

18.

Diurnal Cortisol Variation According to High-Risk Occupational Specialty Within Police: Comparisons Between Frontline, Tactical Officers, and the General Population.

Planche K, Chan JF, Di Nota PM, Beston B, Boychuk E, Collins PI, Andersen JP.

J Occup Environ Med. 2019 Jun;61(6):e260-e265. doi: 10.1097/JOM.0000000000001591.

PMID:
31167225
19.

Molecular prevalence and subtyping of Cryptosporidium hominis among captive long-tailed macaques (Macaca fascicularis) and rhesus macaques (Macaca mulatta) from Hainan Island, southern China.

Zhao W, Zhou H, Jin H, Liu M, Qiu M, Li L, Yin F, Chan JF, Lu G.

Parasit Vectors. 2019 Apr 30;12(1):192. doi: 10.1186/s13071-019-3449-0.

20.

Screening of an FDA-Approved Drug Library with a Two-Tier System Identifies an Entry Inhibitor of Severe Fever with Thrombocytopenia Syndrome Virus.

Yuan S, Chan JF, Ye ZW, Wen L, Tsang TG, Cao J, Huang J, Chan CC, Chik KK, Choi GK, Cai JP, Yin F, Chu H, Liang M, Jin DY, Yuen KY.

Viruses. 2019 Apr 25;11(4). pii: E385. doi: 10.3390/v11040385.

21.

Case Study: Cognitive Restructuring Hypnosis for Chronic Pain in a Quadriplegic Patient.

de la Vega R, Mendoza ME, Chan JF, Jensen MP.

Am J Clin Hypn. 2019 Apr;61(4):394-408. doi: 10.1080/00029157.2018.1537973.

PMID:
31017549
22.

Improving the specific diagnosis of trematode, cestode and nematode infections by a multiplex single-tube real-time PCR assay.

Wong SSY, Poon RWS, To KKW, Chan JFW, Lu G, Xing F, Cheng VCC, Yuen KY.

J Clin Pathol. 2019 Jul;72(7):487-492. doi: 10.1136/jclinpath-2018-205590. Epub 2019 Apr 5.

PMID:
30952829
23.

Diversity of phenotypically non-dermatophyte, non-Aspergillus filamentous fungi causing nail infections: importance of accurate identification and antifungal susceptibility testing.

Tsang CC, Tang JYM, Chan KF, Lee CY, Chan JFW, Ngan AHY, Cheung M, Lau ECL, Li X, Ng RHY, Lai CKC, Fung KSC, Lau SKP, Woo PCY.

Emerg Microbes Infect. 2019;8(1):531-541. doi: 10.1080/22221751.2019.1598781.

24.

Donor-Derived Genotype 4 Hepatitis E Virus Infection, Hong Kong, China, 2018.

Sridhar S, Cheng VCC, Wong SC, Yip CCY, Wu S, Lo AWI, Leung KH, Mak WWN, Cai J, Li X, Chan JFW, Lau SKP, Woo PCY, Lai WM, Kwan TH, Au TWK, Lo CM, Wong SCY, Yuen KY.

Emerg Infect Dis. 2019 Mar;25(3):425-433. doi: 10.3201/eid2503.181563.

25.

Double bonds of unsaturated fatty acids differentially regulate mitochondrial cardiolipin remodeling.

Ting HC, Chen LT, Chen JY, Huang YL, Xin RC, Chan JF, Hsu YH.

Lipids Health Dis. 2019 Feb 14;18(1):53. doi: 10.1186/s12944-019-0990-y.

26.

Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus as a Host-Targeting Antiviral Strategy.

Zhu Z, Chu H, Wen L, Yuan S, Chik KK, Yuen TT, Yip CC, Wang D, Zhou J, Yin F, Jin DY, Kok KH, Yuen KY, Chan JF.

Int J Mol Sci. 2019 Jan 17;20(2). pii: E392. doi: 10.3390/ijms20020392.

27.

Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication.

Yan B, Chu H, Yang D, Sze KH, Lai PM, Yuan S, Shuai H, Wang Y, Kao RY, Chan JF, Yuen KY.

Viruses. 2019 Jan 16;11(1). pii: E73. doi: 10.3390/v11010073.

28.

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target.

Yuan S, Chu H, Chan JF, Ye ZW, Wen L, Yan B, Lai PM, Tee KM, Huang J, Chen D, Li C, Zhao X, Yang D, Chiu MC, Yip C, Poon VK, Chan CC, Sze KH, Zhou J, Chan IH, Kok KH, To KK, Kao RY, Lau JY, Jin DY, Perlman S, Yuen KY.

Nat Commun. 2019 Jan 10;10(1):120. doi: 10.1038/s41467-018-08015-x.

29.

Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins.

Lau SKP, Fan RYY, Luk HKH, Zhu L, Fung J, Li KSM, Wong EYM, Ahmed SS, Chan JFW, Kok RKH, Chan KH, Wernery U, Yuen KY, Woo PCY.

Emerg Microbes Infect. 2018 Dec 10;7(1):209. doi: 10.1038/s41426-018-0208-9.

30.

Identification and characterization of GLDC as host susceptibility gene to severe influenza.

Zhou J, Wang D, Wong BH, Li C, Poon VK, Wen L, Zhao X, Chiu MC, Liu X, Ye Z, Yuan S, Sze KH, Chan JF, Chu H, To KK, Yuen KY.

EMBO Mol Med. 2019 Jan;11(1). pii: e9528. doi: 10.15252/emmm.201809528.

31.

Rat Hepatitis E Virus as Cause of Persistent Hepatitis after Liver Transplant.

Sridhar S, Yip CCY, Wu S, Cai J, Zhang AJ, Leung KH, Chung TWH, Chan JFW, Chan WM, Teng JLL, Au-Yeung RKH, Cheng VCC, Chen H, Lau SKP, Woo PCY, Xia NS, Lo CM, Yuen KY.

Emerg Infect Dis. 2018 Dec;24(12):2241-2250. doi: 10.3201/eid2412.180937.

32.

Emergence of Cytomegalovirus Mononucleosis Syndrome Among Young Adults in Hong Kong Linked to Falling Seroprevalence: Results of a 14-Year Seroepidemiological Study.

Sridhar S, Chung TWH, Chan JFW, Cheng VCC, Lau SKP, Yuen KY, Woo PCY.

Open Forum Infect Dis. 2018 Oct 20;5(10):ofy262. doi: 10.1093/ofid/ofy262. eCollection 2018 Oct.

33.

The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy.

Chan JF, Zhu Z, Chu H, Yuan S, Chik KK, Chan CC, Poon VK, Yip CC, Zhang X, Tsang JO, Zou Z, Tee KM, Shuai H, Lu G, Yuen KY.

Antiviral Res. 2018 Dec;160:38-47. doi: 10.1016/j.antiviral.2018.10.007. Epub 2018 Oct 13.

34.

Comparative evaluation of a laboratory-developed real-time PCR assay and RealStar® Adenovirus PCR Kit for quantitative detection of human adenovirus.

Wong SSY, Yip CCY, Sridhar S, Leung KH, Cheng AKW, Fung AMY, Lam HY, Chan KH, Chan JFW, Cheng VCC, Tang BSF, Yuen KY.

Virol J. 2018 Sep 27;15(1):149. doi: 10.1186/s12985-018-1059-7.

35.

Omega-3 and omega-6 fatty acid differentially impact cardiolipin remodeling in activated macrophage.

Chang WH, Ting HC, Chen WW, Chan JF, Hsu YH.

Lipids Health Dis. 2018 Aug 28;17(1):201. doi: 10.1186/s12944-018-0845-y.

36.

Human tryptophanyl-tRNA synthetase is an IFN-γ-inducible entry factor for Enterovirus.

Yeung ML, Jia L, Yip CCY, Chan JFW, Teng JLL, Chan KH, Cai JP, Zhang C, Zhang AJ, Wong WM, Kok KH, Lau SKP, Woo PCY, Lo JYC, Jin DY, Shih SR, Yuen KY.

J Clin Invest. 2018 Nov 1;128(11):5163-5177. doi: 10.1172/JCI99411. Epub 2018 Oct 15.

37.

Fatal pancytopenia due to albendazole treatment for strongyloidiasis.

Xing F, Ye H, Yang J, Chan JF, Seto WK, Pai PM, Yuen KY, Hung DL.

IDCases. 2018 Apr 4;12:112-116. doi: 10.1016/j.idcr.2018.04.002. eCollection 2018.

38.

Differentiated human airway organoids to assess infectivity of emerging influenza virus.

Zhou J, Li C, Sachs N, Chiu MC, Wong BH, Chu H, Poon VK, Wang D, Zhao X, Wen L, Song W, Yuan S, Wong KK, Chan JF, To KK, Chen H, Clevers H, Yuen KY.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6822-6827. doi: 10.1073/pnas.1806308115. Epub 2018 Jun 11.

39.

Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells.

Chu H, Chan CM, Zhang X, Wang Y, Yuan S, Zhou J, Au-Yeung RK, Sze KH, Yang D, Shuai H, Hou Y, Li C, Zhao X, Poon VK, Leung SP, Yeung ML, Yan J, Lu G, Jin DY, Gao GF, Chan JF, Yuen KY.

J Biol Chem. 2018 Jul 27;293(30):11709-11726. doi: 10.1074/jbc.RA118.001897. Epub 2018 Jun 10.

40.

USE OF NEUROFEEDBACK AND MINDFULNESS TO ENHANCE RESPONSE TO HYPNOSIS TREATMENT IN INDIVIDUALS WITH MULTIPLE SCLEROSIS: Results From a Pilot Randomized Clinical Trial.

Jensen MP, Battalio SL, Chan JF, Edwards KA, Day MA, Sherlin LH, Ehde DM.

Int J Clin Exp Hypn. 2018 Jul-Sep;66(3):231-264. doi: 10.1080/00207144.2018.1460546.

PMID:
29856281
41.

Immunization With a Novel Human Type 5 Adenovirus-Vectored Vaccine Expressing the Premembrane and Envelope Proteins of Zika Virus Provides Consistent and Sterilizing Protection in Multiple Immunocompetent and Immunocompromised Animal Models.

Guo Q, Chan JF, Poon VK, Wu S, Chan CC, Hou L, Yip CC, Ren C, Cai JP, Zhao M, Zhang AJ, Song X, Chan KH, Wang B, Kok KH, Wen Y, Yuen KY, Chen W.

J Infect Dis. 2018 Jul 2;218(3):365-377. doi: 10.1093/infdis/jiy187.

PMID:
29617816
42.

Phosphatidylglycerol Incorporates into Cardiolipin to Improve Mitochondrial Activity and Inhibits Inflammation.

Chen WW, Chao YJ, Chang WH, Chan JF, Hsu YH.

Sci Rep. 2018 Mar 20;8(1):4919. doi: 10.1038/s41598-018-23190-z.

43.

Impact of inter-genotypic recombination and probe cross-reactivity on the performance of the Abbott RealTime HCV Genotype II assay for hepatitis C genotyping.

Sridhar S, Yip CCY, Chan JFW, To KKW, Cheng VCC, Yuen KY.

Diagn Microbiol Infect Dis. 2018 May;91(1):34-37. doi: 10.1016/j.diagmicrobio.2017.12.024. Epub 2018 Jan 11.

PMID:
29434000
44.

Receptor Usage of a Novel Bat Lineage C Betacoronavirus Reveals Evolution of Middle East Respiratory Syndrome-Related Coronavirus Spike Proteins for Human Dipeptidyl Peptidase 4 Binding.

Lau SKP, Zhang L, Luk HKH, Xiong L, Peng X, Li KSM, He X, Zhao PS, Fan RYY, Wong ACP, Ahmed SS, Cai JP, Chan JFW, Sun Y, Jin D, Chen H, Lau TCK, Kok RKH, Li W, Yuen KY, Woo PCY.

J Infect Dis. 2018 Jun 20;218(2):197-207. doi: 10.1093/infdis/jiy018.

45.

Evaluation of the molecular Xpert Xpress Flu/RSV assay vs. Alere i Influenza A & B assay for rapid detection of influenza viruses.

Chen JH, Lam HY, Yip CC, Cheng VC, Chan JF, Leung TH, Sridhar S, Chan KH, Tang BS, Yuen KY.

Diagn Microbiol Infect Dis. 2018 Mar;90(3):177-180. doi: 10.1016/j.diagmicrobio.2017.11.010. Epub 2017 Nov 24.

PMID:
29262988
46.

Clinical characteristics and molecular epidemiology of hepatitis E in Shenzhen, China: a shift toward foodborne transmission of hepatitis E virus infection.

Sridhar S, Lo SK, Xing F, Yang J, Ye H, Chan JF, Teng JL, Huang C, Yip CC, Lau SK, Woo PC.

Emerg Microbes Infect. 2017 Dec 20;6(12):e115. doi: 10.1038/emi.2017.107.

47.

Yeast identification by sequencing, biochemical kits, MALDI-TOF MS and rep-PCR DNA fingerprinting.

Zhao Y, Tsang CC, Xiao M, Chan JFW, Lau SKP, Kong F, Xu Y, Woo PCY.

Med Mycol. 2018 Oct 1;56(7):816-827. doi: 10.1093/mmy/myx118.

PMID:
29228397
48.

Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus.

Zhou J, Li C, Zhao G, Chu H, Wang D, Yan HH, Poon VK, Wen L, Wong BH, Zhao X, Chiu MC, Yang D, Wang Y, Au-Yeung RKH, Chan IH, Sun S, Chan JF, To KK, Memish ZA, Corman VM, Drosten C, Hung IF, Zhou Y, Leung SY, Yuen KY.

Sci Adv. 2017 Nov 15;3(11):eaao4966. doi: 10.1126/sciadv.aao4966. eCollection 2017 Nov.

49.

Japanese Encephalitis Virus Transmitted Via Blood Transfusion, Hong Kong, China.

Cheng VCC, Sridhar S, Wong SC, Wong SCY, Chan JFW, Yip CCY, Chau CH, Au TWK, Hwang YY, Yau CSW, Lo JYC, Lee CK, Yuen KY.

Emerg Infect Dis. 2018 Jan;24(1). doi: 10.3201/eid2401.171297. Epub 2018 Jan 17.

50.

Genotype 4 hepatitis E virus is a cause of chronic hepatitis in renal transplant recipients in Hong Kong.

Sridhar S, Chan JFW, Yap DYH, Teng JLL, Huang C, Yip CCY, Hung IFN, Tang SCW, Lau SKP, Woo PCY, Yuen KY.

J Viral Hepat. 2018 Feb;25(2):209-213. doi: 10.1111/jvh.12799. Epub 2017 Nov 13. No abstract available.

PMID:
28984015

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