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Items: 37

1.

GDC-0810 Pharmacokinetics and Transporter-Mediated Drug Interaction Evaluation with an Endogenous Biomarker in the First-in-Human, Dose Escalation Study.

Cheung KWK, Yoshida K, Cheeti S, Chen B, Morley R, Chan IT, Sahasranaman S, Liu L.

Drug Metab Dispos. 2019 Sep;47(9):966-973. doi: 10.1124/dmd.119.087924. Epub 2019 Jul 2.

PMID:
31266752
2.

Phase Ib study of the MEK inhibitor cobimetinib (GDC-0973) in combination with the PI3K inhibitor pictilisib (GDC-0941) in patients with advanced solid tumors.

Shapiro GI, LoRusso P, Kwak E, Pandya S, Rudin CM, Kurkjian C, Cleary JM, Pilat MJ, Jones S, de Crespigny A, Fredrickson J, Musib L, Yan Y, Wongchenko M, Hsieh HJ, Gates MR, Chan IT, Bendell J.

Invest New Drugs. 2019 Apr 24. doi: 10.1007/s10637-019-00776-6. [Epub ahead of print]

PMID:
31020608
3.

Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132.

Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, Chatrizeh M, Chase ME, Weis O, Zhou Y, Serhan CN, Zon LI.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9252-9257. doi: 10.1073/pnas.1806077115. Epub 2018 Aug 23.

4.

Emergence of G9P[8] rotaviruses in children with acute gastroenteritis in Thailand, 2015-2016.

Chan-It W, Chanta C.

J Med Virol. 2018 Mar;90(3):477-484. doi: 10.1002/jmv.24985. Epub 2017 Nov 14.

PMID:
29077213
5.

A first-in-human phase I study to evaluate the MEK1/2 inhibitor, cobimetinib, administered daily in patients with advanced solid tumors.

Rosen LS, LoRusso P, Ma WW, Goldman JW, Weise A, Colevas AD, Adjei A, Yazji S, Shen A, Johnston S, Hsieh HJ, Chan IT, Sikic BI.

Invest New Drugs. 2016 Oct;34(5):604-13. doi: 10.1007/s10637-016-0374-3. Epub 2016 Jul 16.

PMID:
27424159
6.

Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant.

Spoerke JM, Gendreau S, Walter K, Qiu J, Wilson TR, Savage H, Aimi J, Derynck MK, Chen M, Chan IT, Amler LC, Hampton GM, Johnston S, Krop I, Schmid P, Lackner MR.

Nat Commun. 2016 May 13;7:11579. doi: 10.1038/ncomms11579.

7.

Molecular epidemiology of norovirus associated with gastroenteritis and emergence of norovirus GII.4 variant 2012 in Japanese pediatric patients.

Thongprachum A, Chan-it W, Khamrin P, Saparpakorn P, Okitsu S, Takanashi S, Mizuguchi M, Hayakawa S, Maneekarn N, Ushijima H.

Infect Genet Evol. 2014 Apr;23:65-73. doi: 10.1016/j.meegid.2014.01.030. Epub 2014 Feb 4.

PMID:
24508246
8.

Impact of thyroid status and age on comprehensive geriatric assessment.

E Silva SO, Chan IT, Lobo Santos MA, Cohen M, de La Roque P Araujo M, da Silva Almeida J, Simões A, Givigi HR, Vaisman M, Paixão CM Jr, de Fatima Dos S Teixeira P.

Endocrine. 2014 Sep;47(1):255-65. doi: 10.1007/s12020-013-0077-x. Epub 2013 Nov 1.

9.

Absolute bioavailability and effect of formulation change, food, or elevated pH with rabeprazole on cobimetinib absorption in healthy subjects.

Musib L, Choo E, Deng Y, Eppler S, Rooney I, Chan IT, Dresser MJ.

Mol Pharm. 2013 Nov 4;10(11):4046-54. doi: 10.1021/mp400383x. Epub 2013 Sep 30.

PMID:
24010577
10.

Genetic analysis and homology modeling of capsid protein of norovirus GII.14.

Chan-It W, Thongprachum A, Okitsu S, Mizuguchi M, Ushijima H.

J Med Virol. 2014 Feb;86(2):329-34. doi: 10.1002/jmv.23720. Epub 2013 Sep 5.

PMID:
24009213
11.

Emergence of norovirus GII/4 2006a and 2006b variants in hospitalized children with acute gastroenteritis in Thailand.

Thongprachum A, Khamrin P, Chan-It W, Malasao R, Chaimongkol N, Okitsu S, Mizuguchi M, Maneekarn N, Hayakawa S, Ushijima H.

Clin Lab. 2013;59(3-4):271-6.

PMID:
23724614
12.

Reemergence of new variant G3 rotavirus in Japanese pediatric patients, 2009-2011.

Thongprachum A, Chan-it W, Khamrin P, Okitsu S, Nishimura S, Kikuta H, Yamamoto A, Sugita K, Baba T, Mizuguchi M, Maneekarn N, Hayakawa S, Ushijima H.

Infect Genet Evol. 2013 Jan;13:168-74. doi: 10.1016/j.meegid.2012.09.010. Epub 2012 Oct 31.

PMID:
23123146
13.

Dogs are more sensitive to antagonists of inhibitor of apoptosis proteins than rats and humans: a translational toxicokinetic/toxicodynamic analysis.

Wong H, Budha NR, West K, Blackwood E, Ware JA, Yu R, Darbonne WC, Gould SE, Steigerwalt R, Erickson R, Hop CE, LoRusso P, Eckhardt SG, Wagner A, Chan IT, Mamounas M, Flygare JA, Fairbrother WJ.

Toxicol Sci. 2012 Nov;130(1):205-13. doi: 10.1093/toxsci/kfs235. Epub 2012 Jul 28.

PMID:
22843607
14.

Emergence of a new norovirus GII.6 variant in Japan, 2008-2009.

Chan-It W, Thongprachum A, Khamrin P, Kobayashi M, Okitsu S, Mizuguchi M, Ushijima H.

J Med Virol. 2012 Jul;84(7):1089-96. doi: 10.1002/jmv.23309.

PMID:
22585727
15.

Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).

Flygare JA, Beresini M, Budha N, Chan H, Chan IT, Cheeti S, Cohen F, Deshayes K, Doerner K, Eckhardt SG, Elliott LO, Feng B, Franklin MC, Reisner SF, Gazzard L, Halladay J, Hymowitz SG, La H, LoRusso P, Maurer B, Murray L, Plise E, Quan C, Stephan JP, Young SG, Tom J, Tsui V, Um J, Varfolomeev E, Vucic D, Wagner AJ, Wallweber HJ, Wang L, Ware J, Wen Z, Wong H, Wong JM, Wong M, Wong S, Yu R, Zobel K, Fairbrother WJ.

J Med Chem. 2012 May 10;55(9):4101-13. doi: 10.1021/jm300060k. Epub 2012 Mar 28.

16.

Detection and genetic characterization of norovirus infections in children with acute gastroenteritis in Japan, 2007-2009.

Chan-It W, Thongprachum A, Okitsu S, Nishimura S, Kikuta H, Baba T, Yamamoto A, Sugita K, Hashira S, Tajima T, Mizuguchi M, Ushijima H.

Clin Lab. 2011;57(3-4):213-20.

PMID:
21500729
17.

Seasonal pattern and genotype distribution of sapovirus infection in Japan, 2003-2009.

Dey SK, Phathammavong O, Nguyen TD, Thongprachum A, Chan-It W, Okitsu S, Mizuguchi M, Ushijima H.

Epidemiol Infect. 2012 Jan;140(1):74-7. doi: 10.1017/S0950268811000240. Epub 2011 Mar 4.

PMID:
21371364
18.

Detection of human parechovirus in stool samples collected from children with acute gastroenteritis in Japan during 2007-2008.

Pham NT, Chan-It W, Khamrin P, Nishimura S, Kikuta H, Sugita K, Baba T, Yamamoto A, Shimizu H, Okitsu S, Mizuguchi M, Ushijima H.

J Med Virol. 2011 Feb;83(2):331-6. doi: 10.1002/jmv.21740.

PMID:
21181931
19.

Human bocavirus infection in children with acute gastroenteritis in Japan and Thailand.

Pham NT, Trinh QD, Chan-It W, Khamrin P, Nishimura S, Sugita K, Maneekarn N, Okitsu S, Mizuguchi M, Ushijima H.

J Med Virol. 2011 Feb;83(2):286-90. doi: 10.1002/jmv.21876.

PMID:
21181924
20.

Detection and genetic characterization of rotavirus infections in non-hospitalized children with acute gastroenteritis in Japan, 2007-2009.

Chan-it W, Thongprachum A, Dey SK, Phan TG, Khamrin P, Okitsu S, Nishimura S, Kobayashi M, Kikuta H, Baba T, Yamamoto A, Sugita K, Hashira S, Tajima T, Ishida S, Mizuguchi M, Ushijima H.

Infect Genet Evol. 2011 Mar;11(2):415-22. doi: 10.1016/j.meegid.2010.11.018. Epub 2010 Dec 9.

PMID:
21145986
21.

Comparison of the rapid methods for screening of group a rotavirus in stool samples.

Khamrin P, Tran DN, Chan-it W, Thongprachum A, Okitsu S, Maneekarn N, Ushijima H.

J Trop Pediatr. 2011 Oct;57(5):375-7. doi: 10.1093/tropej/fmq101. Epub 2010 Oct 28.

PMID:
21030457
22.

A novel RT-multiplex PCR for detection of Aichi virus, human parechovirus, enteroviruses, and human bocavirus among infants and children with acute gastroenteritis.

Pham NT, Trinh QD, Chan-It W, Khamrin P, Shimizu H, Okitsu S, Mizuguchi M, Ushijima H.

J Virol Methods. 2010 Oct;169(1):193-7. doi: 10.1016/j.jviromet.2010.07.038. Epub 2010 Aug 4.

PMID:
20691209
23.

Epidemiology and molecular characterization of sapovirus and astrovirus in Japan, 2008-2009.

Chan-it W, Thongprachum A, Okitsu S, Mizuguchi M, Ushijima H.

Jpn J Infect Dis. 2010 Jul;63(4):302-3. No abstract available.

24.

Evaluation of the newly developed immunochromatography test kit for rapid detection and differentiation of norovirus GI and GII.

Khamrin P, Chan-it W, Satou K, Nanba Y, Yamashita Y, Okitsu S, Maneekarn N, Ushijima H.

J Trop Pediatr. 2010 Oct;56(5):368-9. doi: 10.1093/tropej/fmp134. Epub 2010 Jan 19. No abstract available.

PMID:
20085965
25.

Evaluation of a rapid immunochromatography strip test for detection of astrovirus in stool specimens.

Khamrin P, Dey SK, Chan-it W, Thongprachum A, Satou K, Okitsu S, Maneekarn N, Ushijima H.

J Trop Pediatr. 2010 Apr;56(2):129-31. doi: 10.1093/tropej/fmp055. Epub 2009 Jul 3. No abstract available.

PMID:
19578128
26.

Immunochromatography test for rapid detection of norovirus in fecal specimens.

Khamrin P, Takanashi S, Chan-It W, Kobayashi M, Nishimura S, Katsumata N, Okitsu S, Maneekarn N, Nishio O, Ushijima H.

J Virol Methods. 2009 May;157(2):219-22. doi: 10.1016/j.jviromet.2008.12.012. Epub 2009 Jan 10.

PMID:
19138707
27.

Molecular characterization of VP4, VP6, VP7, NSP4, and NSP5/6 genes identifies an unusual G3P[10] human rotavirus strain.

Khamrin P, Maneekarn N, Peerakome S, Malasao R, Thongprachum A, Chan-It W, Mizuguchi M, Okitsu S, Ushijima H.

J Med Virol. 2009 Jan;81(1):176-82. doi: 10.1002/jmv.21336.

PMID:
19031442
28.

A simple screening assay for receptor switching of avian influenza viruses.

Suptawiwat O, Kongchanagul A, Chan-It W, Thitithanyanont A, Wiriyarat W, Chaichuen K, Songserm T, Suzuki Y, Puthavathana P, Auewarakul P.

J Clin Virol. 2008 Jun;42(2):186-9. doi: 10.1016/j.jcv.2008.01.014. Epub 2008 Mar 17.

PMID:
18343718
29.

Multiple combinations of P[13]-like genotype with G3, G4, and G5 in porcine rotaviruses.

Chan-It W, Khamrin P, Saekhow P, Pantip C, Thongprachum A, Peerakome S, Ushijima H, Maneekarn N.

J Clin Microbiol. 2008 Apr;46(4):1169-73. doi: 10.1128/JCM.00856-07. Epub 2008 Jan 30.

30.

WITHDRAWN: Molecular Characterization of VP4 and VP7 Genes of Nontypeable Strains Identifies a Novel P[28] Genotype in Porcine Rotaviruses.

Chan-It W, Khamrin P, Saekhow P, Pantip C, Thongprachum A, Peerakome S, Ushijima H, Maneekarn N.

J Clin Microbiol. 2007 Apr 19. [Epub ahead of print]

PMID:
17409206
31.

Novel porcine rotavirus of genotype P[27] shares new phylogenetic lineage with G2 porcine rotavirus strain.

Khamrin P, Maneekarn N, Peerakome S, Chan-it W, Yagyu F, Okitsu S, Ushijima H.

Virology. 2007 May 10;361(2):243-52. Epub 2007 Jan 9.

32.

Detection of rare G3P[19] porcine rotavirus strains in Chiang Mai, Thailand, provides evidence for origin of the VP4 genes of Mc323 and Mc345 human rotaviruses.

Maneekarn N, Khamrin P, Chan-it W, Peerakome S, Sukchai S, Pringprao K, Ushijima H.

J Clin Microbiol. 2006 Nov;44(11):4113-9. Epub 2006 Sep 20.

33.

Oncogenic K-ras cooperates with PML-RAR alpha to induce an acute promyelocytic leukemia-like disease.

Chan IT, Kutok JL, Williams IR, Cohen S, Moore S, Shigematsu H, Ley TJ, Akashi K, Le Beau MM, Gilliland DG.

Blood. 2006 Sep 1;108(5):1708-15. Epub 2006 May 4.

34.

Oncogenic K-ras in mouse models of myeloproliferative disease and acute myeloid leukemia.

Chan IT, Gilliland DG.

Cell Cycle. 2004 May;3(5):536-7. Epub 2004 May 5.

PMID:
15020845
35.

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease.

Chan IT, Kutok JL, Williams IR, Cohen S, Kelly L, Shigematsu H, Johnson L, Akashi K, Tuveson DA, Jacks T, Gilliland DG.

J Clin Invest. 2004 Feb;113(4):528-38.

36.

Structure of the P22 att site. Conservation and divergence in the lambda motif of recombinogenic complexes.

Smith-Mungo L, Chan IT, Landy A.

J Biol Chem. 1994 Aug 12;269(32):20798-805.

37.

Thymic selection of cytotoxic T cells independent of CD8 alpha-Lck association.

Chan IT, Limmer A, Louie MC, Bullock ED, Fung-Leung WP, Mak TW, Loh DY.

Science. 1993 Sep 17;261(5128):1581-4.

PMID:
8372352

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