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The Mutation-Associated Neoantigen Functional Expansion of Specific T cells (MANAFEST) assay: a sensitive platform for monitoring antitumor immunity.

Danilova L, Anagnostou V, Caushi JX, Sidhom JW, Guo H, Chan HY, Suri P, Tam AJ, Zhang J, El Asmar M, Marrone KA, Naidoo J, Brahmer JR, Forde PM, Baras AS, Cope L, Velculescu VE, Pardoll D, Housseau F, Smith KN.

Cancer Immunol Res. 2018 Jun 12. pii: canimm.0129.2018. doi: 10.1158/2326-6066.CIR-18-0129. [Epub ahead of print]


Quick screen of patients' numeracy and document literacy skills: the factor structure of the Newest Vital Sign.

Huang YM, Shiyanbola OO, Smith PD, Chan HY.

Patient Prefer Adherence. 2018 May 17;12:853-859. doi: 10.2147/PPA.S165994. eCollection 2018.


OpenSim as a preliminary kinematic testing platform for the development of total knee arthroplasty implants.

Chan HY, Walker PS.

J Biomech. 2018 May 18. pii: S0021-9290(18)30365-8. doi: 10.1016/j.jbiomech.2018.05.014. [Epub ahead of print]


Neoadjuvant PD-1 Blockade in Resectable Lung Cancer.

Forde PM, Chaft JE, Smith KN, Anagnostou V, Cottrell TR, Hellmann MD, Zahurak M, Yang SC, Jones DR, Broderick S, Battafarano RJ, Velez MJ, Rekhtman N, Olah Z, Naidoo J, Marrone KA, Verde F, Guo H, Zhang J, Caushi JX, Chan HY, Sidhom JW, Scharpf RB, White J, Gabrielson E, Wang H, Rosner GL, Rusch V, Wolchok JD, Merghoub T, Taube JM, Velculescu VE, Topalian SL, Brahmer JR, Pardoll DM.

N Engl J Med. 2018 May 24;378(21):1976-1986. doi: 10.1056/NEJMoa1716078. Epub 2018 Apr 16.


Neuronal adaptor FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating ELMO1.

Li W, Tam KMV, Chan WWR, Koon AC, Ngo JCK, Chan HYE, Lau KF.

J Biol Chem. 2018 May 18;293(20):7674-7688. doi: 10.1074/jbc.RA117.000505. Epub 2018 Apr 3.


Sophora flavescens protects against mycobacterial Trehalose Dimycolate-induced lung granuloma by inhibiting inflammation and infiltration of macrophages.

Liu D, Chan BC, Cheng L, Tsang MS, Zhu J, Wong CW, Jiao D, Chan HY, Leung PC, Lam CW, Wong CK.

Sci Rep. 2018 Mar 2;8(1):3903. doi: 10.1038/s41598-018-22286-w.


Acoustic characteristics of highly distinguishable Cantonese entering and non-entering tones.

Wong P, Chan HY.

J Acoust Soc Am. 2018 Feb;143(2):765. doi: 10.1121/1.5021251.


Association between dehydration on admission and postoperative complications in older persons undergoing orthopaedic surgery.

Chan HYL, Cheng A, Cheung SSS, Pang WW, Ma WY, Mok LC, Wong WK, Lee DTF.

J Clin Nurs. 2018 Mar 1. doi: 10.1111/jocn.14336. [Epub ahead of print]


Transitions of Developmental Trajectories of Depressive Symptoms Between Junior and Senior High School Among Youths in Taiwan: Linkages to Symptoms in Young Adulthood.

Wang YL, Chan HY, Chen PC.

J Abnorm Child Psychol. 2018 Feb 21. doi: 10.1007/s10802-018-0408-8. [Epub ahead of print]


Comparison of the outcome measures from different pathways post total knee arthroplasty.

Chan HY, Sultana R, Yeo SJ, Chia SL, Pang HN, Lo NN.

Singapore Med J. 2018 Jan 26. doi: 10.11622/smedj.2018011. [Epub ahead of print]


Statistical Design of Experiment (DoE) based development and optimization of DB213 in situ thermosensitive gel for intranasal delivery.

Wang Q, Wong CH, Chan HYE, Lee WY, Zuo Z.

Int J Pharm. 2018 Mar 25;539(1-2):50-57. doi: 10.1016/j.ijpharm.2018.01.032. Epub 2018 Jan 31.


Consensus statements on the clinical understanding and use of milnacipran in Hong Kong.

Lee WK, Au Yeung KL, Lam HB, Wong CK, Au MK, Chan HYK, Cheung YWE, Chui WH, Wong TCV, Fu CK, Sham SK, Mak KY.

Hum Psychopharmacol. 2018 Mar;33(2):e2651. doi: 10.1002/hup.2651. Epub 2018 Jan 17. Review.


Staff preparedness for providing palliative and end-of-life care in long-term care homes: Instrument development and validation.

Chan HY, Chun GK, Man CW, Leung EM.

Geriatr Gerontol Int. 2018 May;18(5):745-749. doi: 10.1111/ggi.13244. Epub 2018 Jan 16.


Switching antipsychotic treatment to aripiprazole in psychotic patients with neuroleptic-induced tardive dyskinesia: a 24-week follow-up study.

Chan CH, Chan HY, Chen YC.

Int Clin Psychopharmacol. 2018 May;33(3):155-162. doi: 10.1097/YIC.0000000000000208.


A peptidylic inhibitor for neutralizing expanded CAG RNA-induced nucleolar stress in polyglutamine diseases.

Zhang Q, Chen ZS, An Y, Liu H, Hou Y, Li W, Lau KF, Koon AC, Ngo JCK, Chan HYE.

RNA. 2018 Apr;24(4):486-498. doi: 10.1261/rna.062703.117. Epub 2018 Jan 2.


MicroRNAs regulate the sesquiterpenoid hormonal pathway in Drosophila and other arthropods.

Qu Z, Bendena WG, Nong W, Siggens KW, Noriega FG, Kai ZP, Zang YY, Koon AC, Chan HYE, Chan TF, Chu KH, Lam HM, Akam M, Tobe SS, Lam Hui JH.

Proc Biol Sci. 2017 Dec 20;284(1869). pii: 20171827. doi: 10.1098/rspb.2017.1827.


The association between rehabilitation programs and metabolic syndrome in chronic inpatients with schizophrenia.

Lin YC, Lai CL, Chan HY.

Psychiatry Res. 2017 Dec 2;260:227-232. doi: 10.1016/j.psychres.2017.11.081. [Epub ahead of print]


Risk factors for readmission in schizophrenia patients following involuntary admission.

Hung YY, Chan HY, Pan YJ.

PLoS One. 2017 Oct 26;12(10):e0186768. doi: 10.1371/journal.pone.0186768. eCollection 2017.


A nonpharmacological approach to improve sleep quality in older adults.

Rawtaer I, Mahendran R, Chan HY, Lei F, Kua EH.

Asia Pac Psychiatry. 2018 Jun;10(2):e12301. doi: 10.1111/appy.12301. Epub 2017 Oct 10.


Development and Evaluation of Multimedia Interventions to Promote Breast and Cervical Health among South Asian Women in Hong Kong: A Project Protocol.

So WKW, Chan DNS, Rana T, Law BMH, Leung DYP, Chan HYL, Ng CC, Chair SY, Chan CWH.

Asia Pac J Oncol Nurs. 2017 Oct-Dec;4(4):361-365. doi: 10.4103/apjon.apjon_37_17.


Human papillomavirus infection and squamous cell carcinoma in Hong Kong: a case-control study.

Chan PK, To KF, Tsang SH, Lau CH, Kwong WH, Chan YH.

Hong Kong Med J. 2017 Aug;23 Suppl 5(4):8-11. No abstract available.


A brain-targeting lipidated peptide for neutralizing RNA-mediated toxicity in Polyglutamine Diseases.

Zhang Q, Yang M, Sørensen KK, Madsen CS, Boesen JT, An Y, Peng SH, Wei Y, Wang Q, Jensen KJ, Zuo Z, Chan HYE, Ngo JCK.

Sci Rep. 2017 Sep 21;7(1):12077. doi: 10.1038/s41598-017-11695-y.


Effects of horticultural therapy on elderly' health: protocol of a randomized controlled trial.

Chan HY, Ho RC, Mahendran R, Ng KS, Tam WW, Rawtaer I, Tan CH, Larbi A, Feng L, Sia A, Ng MK, Gan GL, Kua EH.

BMC Geriatr. 2017 Aug 29;17(1):192. doi: 10.1186/s12877-017-0588-z.


AF-6 Protects Against Dopaminergic Dysfunction and Mitochondrial Abnormalities in Drosophila Models of Parkinson's Disease.

Basil AH, Sim JPL, Lim GGY, Lin S, Chan HY, Engelender S, Lim KL.

Front Cell Neurosci. 2017 Aug 10;11:241. doi: 10.3389/fncel.2017.00241. eCollection 2017.


An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos.

Lee WJ, Chatterjee S, Yap SP, Lim SL, Xing X, Kraus P, Sun W, Hu X, Sivakamasundari V, Chan HY, Kolatkar PR, Prabhakar S, Lufkin T.

Biomed Res Int. 2017;2017:8932583. doi: 10.1155/2017/8932583. Epub 2017 May 28.


Conformational flexibility in the RNA stem-loop structures formed by CAG repeats.

Guo P, Chan HYE, Lam SL.

FEBS Lett. 2017 Jun;591(12):1752-1760. doi: 10.1002/1873-3468.12672. Epub 2017 May 27.


Common urological problems in children: inguinoscrotal pathologies.

Chan IH, Wong KK.

Hong Kong Med J. 2017 Jun;23(3):272-81. doi: 10.12809/hkmj165061. Epub 2017 May 5. Review.


Significant positive association of endotoxemia with histological severity in 237 patients with non-alcoholic fatty liver disease.

Pang J, Xu W, Zhang X, Wong GL, Chan AW, Chan HY, Tse CH, Shu SS, Choi PC, Chan HL, Yu J, Wong VW.

Aliment Pharmacol Ther. 2017 Jul;46(2):175-182. doi: 10.1111/apt.14119. Epub 2017 May 2.


Transformation of excess mortality in people with schizophrenia and bipolar disorder in Taiwan.

Pan YJ, Yeh LL, Chan HY, Chang CK.

Psychol Med. 2017 Oct;47(14):2483-2493. doi: 10.1017/S0033291717001040. Epub 2017 Apr 26.


Posterior reversible encephalopathy syndrome in a postpartum hemorrhagic woman without hypertension: A case report.

Lio CF, Lee YH, Chan HY, Yu CC, Peng NJ, Chan HP.

Medicine (Baltimore). 2017 Apr;96(16):e6690. doi: 10.1097/MD.0000000000006690.


Drosophila melanogaster As a Model Organism to Study RNA Toxicity of Repeat Expansion-Associated Neurodegenerative and Neuromuscular Diseases.

Koon AC, Chan HY.

Front Cell Neurosci. 2017 Mar 21;11:70. doi: 10.3389/fncel.2017.00070. eCollection 2017. Review.


Best practices to prevent transmission and control outbreaks of hand, foot, and mouth disease in childcare facilities: a systematic review.

Chan JH, Law CK, Hamblion E, Fung H, Rudge J.

Hong Kong Med J. 2017 Apr;23(2):177-90. doi: 10.12809/hkmj166098. Epub 2017 Mar 17. Review.


A cross-sectional study on compliance with topical glaucoma medication and its associated socioeconomic burden for a Chinese population.

Lui MH, Lam JC, Kwong YL, Wong TS, Cheung PL, Lai SS, Yuen PL, Lam WY, Chan HY, Wong YF, Lai JS, Shih KC.

Int J Ophthalmol. 2017 Feb 18;10(2):293-299. doi: 10.18240/ijo.2017.02.18. eCollection 2017.


Expanded polyalanine tracts function as nuclear export signals and promote protein mislocalization via eEF1A1 factor.

Li L, Ng NK, Koon AC, Chan HY.

J Biol Chem. 2017 Apr 7;292(14):5784-5800. doi: 10.1074/jbc.M116.763599. Epub 2017 Feb 28.


A Nuanced Look at Women in STEM Fields at Two-Year Colleges: Factors That Shape Female Students' Transfer Intent.

Wang X, Chan HY, Soffa SJ, Nachman BR.

Front Psychol. 2017 Feb 6;8:146. doi: 10.3389/fpsyg.2017.00146. eCollection 2017.


Minimal Clinically Important Differences for American Orthopaedic Foot & Ankle Society Score in Hallux Valgus Surgery.

Chan HY, Chen JY, Zainul-Abidin S, Ying H, Koo K, Rikhraj IS.

Foot Ankle Int. 2017 May;38(5):551-557. doi: 10.1177/1071100716688724. Epub 2017 Feb 13.


Semiautomated Alignment of High-Throughput Metabolite Profiles with Chemometric Tools.

Wu ZY, Zeng ZD, Xiao ZD, Mok DK, Liang YZ, Chau FT, Chan HY.

J Anal Methods Chem. 2017;2017:9402045. doi: 10.1155/2017/9402045. Epub 2017 Jan 12.


Atomization of High-Viscosity Fluids for Aromatherapy Using Micro-heaters for Heterogeneous Bubble Nucleation.

Law J, Kong KW, Chan HY, Sun W, Li WJ, Chau EB, Chan GK.

Sci Rep. 2017 Jan 11;7:40289. doi: 10.1038/srep40289.


Time to Discontinuation of Second-Generation Antipsychotics Versus Haloperidol and Sulpiride in People With Schizophrenia: A Naturalistic, Comparative Study.

Chan HY, Pan YJ, Chen JJ, Chen CH.

J Clin Psychopharmacol. 2017 Feb;37(1):13-20. doi: 10.1097/JCP.0000000000000623.


Effects of mind-body exercises on the physiological and psychosocial well-being of individuals with Parkinson's disease: A systematic review and meta-analysis.

Kwok JY, Choi KC, Chan HY.

Complement Ther Med. 2016 Dec;29:121-131. doi: 10.1016/j.ctim.2016.09.016. Epub 2016 Sep 22.


Three-year mortality in relation to early hospitalization and number of outpatient clinic visits in people with newly diagnosed bipolar disorder.

Pan YJ, Yeh LL, Chen YC, Chan HY.

Gen Hosp Psychiatry. 2016 Nov - Dec;43:32-37. doi: 10.1016/j.genhosppsych.2016.08.007. Epub 2016 Sep 9.


Five-year outcomes of western mental health training for Traditional Chinese Medicine practitioners.

Lam TP, Mak KY, Lam KF, Chan HY, Sun KS.

BMC Psychiatry. 2016 Oct 26;16(1):363.


Emotion regulation and emotional distress: The mediating role of hope on reappraisal and anxiety/depression in newly diagnosed cancer patients.

Peh CX, Liu J, Bishop GD, Chan HY, Chua SM, Kua EH, Mahendran R.

Psychooncology. 2017 Aug;26(8):1191-1197. doi: 10.1002/pon.4297. Epub 2016 Oct 24.


Tai chi qigong as a means to improve night-time sleep quality among older adults with cognitive impairment: a pilot randomized controlled trial.

Chan AW, Yu DS, Choi KC, Lee DT, Sit JW, Chan HY.

Clin Interv Aging. 2016 Sep 16;11:1277-1286. eCollection 2016.


An Age-Friendly Living Environment as Seen by Chinese Older Adults: A "Photovoice" Study.

Chan AW, Chan HY, Chan IK, Cheung BY, Lee DT.

Int J Environ Res Public Health. 2016 Sep 13;13(9). pii: E913. doi: 10.3390/ijerph13090913.


Secondary Metabolites of the Endophytic Fungus Lachnum abnorme from Ardisia cornudentata.

Chang HS, Lin CH, Chen YS, Wang HC, Chan HY, Hsieh SY, Wu HC, Cheng MJ, Yuan GF, Lin SY, Lin YJ, Chen IS.

Int J Mol Sci. 2016 Sep 8;17(9). pii: E1512. doi: 10.3390/ijms17091512.


Quality of life and palliative care needs of elderly patients with advanced heart failure.

Chan HY, Yu DS, Leung DY, Chan AW, Hui E.

J Geriatr Cardiol. 2016 Jul;13(5):420-4. doi: 10.11909/j.issn.1671-5411.2016.05.016.


Evaluation of a tablet-based instruction of breathing technique in patients with COPD.

Chan HY, Dai YT, Hou IC.

Int J Med Inform. 2016 Oct;94:263-70. doi: 10.1016/j.ijmedinf.2016.06.018. Epub 2016 Aug 2.


Concurrent fatty liver increases risk of hepatocellular carcinoma among patients with chronic hepatitis B.

Chan AW, Wong GL, Chan HY, Tong JH, Yu YH, Choi PC, Chan HL, To KF, Wong VW.

J Gastroenterol Hepatol. 2017 Mar;32(3):667-676. doi: 10.1111/jgh.13536.


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