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Items: 1 to 50 of 196

1.

Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma.

Wang X, Blackaby W, Allen V, Chan GKY, Chang JH, Chiang PC, Diène C, Drummond J, Do S, Fan E, Harstad EB, Hodges A, Hu H, Jia W, Kofie W, Kolesnikov A, Lyssikatos JP, Ly J, Matteucci M, Moffat JG, Munugalavadla V, Murray J, Nash D, Noland CL, Del Rosario G, Ross L, Rouse C, Sharpe A, Slaga D, Sun M, Tsui V, Wallweber H, Yu SF, Ebens AJ.

J Med Chem. 2019 Feb 20. doi: 10.1021/acs.jmedchem.8b01857. [Epub ahead of print]

PMID:
30715878
2.

Isoorientin derived from Gentiana veitchiorum Hemsl. flowers inhibits melanogenesis by down-regulating MITF-induced tyrosinase expression.

Wu QY, Wong ZC, Wang C, Fung AH, Wong EO, Chan GK, Dong TT, Chen Y, Tsim KW.

Phytomedicine. 2018 Dec 10;57:129-136. doi: 10.1016/j.phymed.2018.12.006. [Epub ahead of print]

PMID:
30668315
3.

Health Emergency Disaster Risk Management of Public Transport Systems: A Population-Based Study after the 2017 Subway Fire in Hong Kong, China.

Chan EYY, Huang Z, Hung KKC, Chan GKW, Lam HCY, Lo ESK, Yeung MPS.

Int J Environ Res Public Health. 2019 Jan 15;16(2). pii: E228. doi: 10.3390/ijerph16020228.

4.

The electronic complexity of the ground-state of the FeMo cofactor of nitrogenase as relevant to quantum simulations.

Li Z, Li J, Dattani NS, Umrigar CJ, Chan GK.

J Chem Phys. 2019 Jan 14;150(2):024302. doi: 10.1063/1.5063376.

PMID:
30646701
5.

Inhibiting Wee1 and ATR kinases produces tumor-selective synthetic lethality and suppresses metastasis.

Bukhari AB, Lewis CW, Pearce JJ, Luong D, Chan GK, Gamper AM.

J Clin Invest. 2019 Feb 18. pii: 122622. doi: 10.1172/JCI122622. [Epub ahead of print]

6.

Multifocal multiphoton volumetric imaging approach for high-speed time-resolved Förster resonance energy transfer imaging in vivo.

Poland SP, Chan GK, Levitt JA, Krstajić N, Erdogan AT, Henderson RK, Parsons M, Ameer-Beg SM.

Opt Lett. 2018 Dec 15;43(24):6057-6060. doi: 10.1364/OL.43.006057.

PMID:
30548010
7.

Binding of Resveratrol to Vascular Endothelial Growth Factor Suppresses Angiogenesis by Inhibiting the Receptor Signaling.

Hu WH, Duan R, Xia YT, Xiong QP, Wang HY, Chan GK, Liu SY, Dong TT, Qin QW, Tsim KW.

J Agric Food Chem. 2019 Jan 30;67(4):1127-1137. doi: 10.1021/acs.jafc.8b05977. Epub 2019 Jan 17.

PMID:
30525561
8.

Primary Care 2.0: Design of a Transformational Team-Based Practice Model to Meet the Quadruple Aim.

Brown-Johnson CG, Chan GK, Winget M, Shaw JG, Patton K, Hussain R, Olayiwola JN, Chang SI, Mahoney M.

Am J Med Qual. 2018 Nov 9:1062860618802365. doi: 10.1177/1062860618802365. [Epub ahead of print]

PMID:
30409021
9.

A Time-Dependent Formulation of Coupled-Cluster Theory for Many-Fermion Systems at Finite Temperature.

White AF, Chan GK.

J Chem Theory Comput. 2018 Nov 13;14(11):5690-5700. doi: 10.1021/acs.jctc.8b00773. Epub 2018 Oct 15.

PMID:
30260642
10.

Kindlin-1 Regulates Epidermal Growth Factor Receptor Signaling.

Michael M, Begum R, Chan GK, Whitewood AJ, Matthews DR, Goult BT, McGrath JA, Parsons M.

J Invest Dermatol. 2019 Feb;139(2):369-379. doi: 10.1016/j.jid.2018.08.020. Epub 2018 Sep 21.

11.

Complete digestion of edible bird's nest releases free N-acetylneuraminic acid and small peptides: an efficient method to improve functional properties.

Wong ZCF, Chan GKL, Wu KQY, Poon KKM, Chen Y, Dong TTX, Tsim KWK.

Food Funct. 2018 Oct 17;9(10):5139-5149. doi: 10.1039/c8fo00991k.

PMID:
30206602
12.

Development of Hospice and Palliative Medicine Knowledge and Skills for Emergency Medicine Residents: Using the Accreditation Council for Graduate Medical Education Milestone Framework.

Shoenberger J, Lamba S, Goett R, DeSandre P, Aberger K, Bigelow S, Brandtman T, Chan GK, Zalenski R, Wang D, Rosenberg M, Jubanyik K.

AEM Educ Train. 2018 Mar 22;2(2):130-145. doi: 10.1002/aet2.10088. eCollection 2018 Apr.

PMID:
30051080
13.

The Promotion of 'Grab Bags' as a Disaster Risk Reduction Strategy.

Pickering CJ, O'Sullivan TL, Morris A, Mark C, McQuirk D, Chan EY, Guy E, Chan GK, Reddin K, Throp R, Tsuzuki S, Yeung T, Murray V.

PLoS Curr. 2018 Jul 6;10. pii: ecurrents.dis.223ac4322834aa0bb0d6824ee424e7f8. doi: 10.1371/currents.dis.223ac4322834aa0bb0d6824ee424e7f8.

14.

Polydatin suppresses VEGF-induced angiogenesis through binding with VEGF and inhibiting its receptor signaling.

Hu WH, Wang HY, Kong XP, Xiong QP, Poon KK, Xu L, Duan R, Chan GK, Dong TT, Tsim KW.

FASEB J. 2019 Jan;33(1):532-544. doi: 10.1096/fj.201800750R. Epub 2018 Jul 10.

PMID:
29989844
15.

A Perturbative Density Matrix Renormalization Group Algorithm for Large Active Spaces.

Guo S, Li Z, Chan GK.

J Chem Theory Comput. 2018 Aug 14;14(8):4063-4071. doi: 10.1021/acs.jctc.8b00273. Epub 2018 Jul 2.

PMID:
29927592
16.

Communication: An efficient stochastic algorithm for the perturbative density matrix renormalization group in large active spaces.

Guo S, Li Z, Chan GK.

J Chem Phys. 2018 Jun 14;148(22):221104. doi: 10.1063/1.5031140.

PMID:
29907045
17.

Exact Fluctuations of Nonequilibrium Steady States from Approximate Auxiliary Dynamics.

Ray U, Chan GK, Limmer DT.

Phys Rev Lett. 2018 May 25;120(21):210602. doi: 10.1103/PhysRevLett.120.210602.

18.

Electron paramagnetic resonance g-tensors from state interaction spin-orbit coupling density matrix renormalization group.

Sayfutyarova ER, Chan GK.

J Chem Phys. 2018 May 14;148(18):184103. doi: 10.1063/1.5020079.

PMID:
29764129
19.

The Fate of Atomic Spin in Atomic Scattering off Surfaces.

Kretchmer JS, Chan GK.

J Phys Chem Lett. 2018 Jun 7;9(11):2863-2868. doi: 10.1021/acs.jpclett.8b00932. Epub 2018 May 17.

PMID:
29763324
20.

Origin of Red Color in Edible Bird's Nests Directed by the Binding of Fe Ions to Acidic Mammalian Chitinase-like Protein.

Wong ZCF, Chan GKL, Dong TTX, Tsim KWK.

J Agric Food Chem. 2018 Jun 6;66(22):5644-5653. doi: 10.1021/acs.jafc.8b01500. Epub 2018 May 23.

PMID:
29751728
21.

Quality Control on Herbal Medicine and Its Application.

Chan GK, Wu R, Chen VP, Zhu KY, Du Y.

Evid Based Complement Alternat Med. 2018 Mar 15;2018:3294398. doi: 10.1155/2018/3294398. eCollection 2018. No abstract available.

22.

Quercetin Potentiates the NGF-Induced Effects in Cultured PC 12 Cells: Identification by HerboChips Showing a Binding with NGF.

Chan GKL, Hu WWH, Zheng ZX, Huang M, Lin YXY, Wang CY, Gong AGW, Yang XY, Tsim KWK, Dong TTX.

Evid Based Complement Alternat Med. 2018 Feb 28;2018:1502457. doi: 10.1155/2018/1502457. eCollection 2018.

23.

The extract of Polygoni Cuspidati Rhizoma et Radix suppresses the vascular endothelial growth factor-induced angiogenesis.

Hu WH, Chan GK, Lou JS, Wu QY, Wang HY, Duan R, Cheng MY, Dong TT, Tsim KW.

Phytomedicine. 2018 Mar 15;42:135-143. doi: 10.1016/j.phymed.2018.03.029. Epub 2018 Mar 17.

PMID:
29655679
24.

Importance sampling large deviations in nonequilibrium steady states. I.

Ray U, Chan GK, Limmer DT.

J Chem Phys. 2018 Mar 28;148(12):124120. doi: 10.1063/1.5003151.

PMID:
29604886
25.

Quantum Simulation of Electronic Structure with Linear Depth and Connectivity.

Kivlichan ID, McClean J, Wiebe N, Gidney C, Aspuru-Guzik A, Chan GK, Babbush R.

Phys Rev Lett. 2018 Mar 16;120(11):110501. doi: 10.1103/PhysRevLett.120.110501.

PMID:
29601758
26.

Effect of curcumin on amyloid-like aggregates generated from methionine-oxidized apolipoprotein A-I.

Krishnamoorthy A, Tavoosi N, Chan GKL, Liu J, Ren G, Cavigiolio G, Ryan RO.

FEBS Open Bio. 2018 Jan 10;8(2):302-310. doi: 10.1002/2211-5463.12372. eCollection 2018 Feb.

27.

A real-time extension of density matrix embedding theory for non-equilibrium electron dynamics.

Kretchmer JS, Chan GK.

J Chem Phys. 2018 Feb 7;148(5):054108. doi: 10.1063/1.5012766.

PMID:
29421885
28.

Methionine oxidized apolipoprotein A-I at the crossroads of HDL biogenesis and amyloid formation.

Witkowski A, Chan GKL, Boatz JC, Li NJ, Inoue AP, Wong JC, van der Wel PCA, Cavigiolio G.

FASEB J. 2018 Jun;32(6):3149-3165. doi: 10.1096/fj.201701127R. Epub 2018 Jan 17.

PMID:
29401604
29.

Lowering of the complexity of quantum chemistry methods by choice of representation.

Mardirossian N, McClain JD, Chan GK.

J Chem Phys. 2018 Jan 28;148(4):044106. doi: 10.1063/1.5007779.

PMID:
29390857
30.

Medical and health risks associated with communicable diseases of Rohingya refugees in Bangladesh 2017.

Chan EYY, Chiu CP, Chan GKW.

Int J Infect Dis. 2018 Mar;68:39-43. doi: 10.1016/j.ijid.2018.01.001. Epub 2018 Jan 9.

31.

Stripe order in the underdoped region of the two-dimensional Hubbard model.

Zheng BX, Chung CM, Corboz P, Ehlers G, Qin MP, Noack RM, Shi H, White SR, Zhang S, Chan GK.

Science. 2017 Dec 1;358(6367):1155-1160. doi: 10.1126/science.aam7127.

PMID:
29191901
32.

Ginkgetin induces autophagic cell death through p62/SQSTM1-mediated autolysosome formation and redox setting in non-small cell lung cancer.

Lou JS, Bi WC, Chan GKL, Jin Y, Wong CW, Zhou ZY, Wang HY, Yao P, Dong TTX, Tsim KWK.

Oncotarget. 2017 Oct 16;8(54):93131-93148. doi: 10.18632/oncotarget.21862. eCollection 2017 Nov 3.

33.

Gaussian and plane-wave mixed density fitting for periodic systems.

Sun Q, Berkelbach TC, McClain JD, Chan GK.

J Chem Phys. 2017 Oct 28;147(16):164119. doi: 10.1063/1.4998644.

PMID:
29096515
34.

Time-Step Targeting Time-Dependent and Dynamical Density Matrix Renormalization Group Algorithms with ab Initio Hamiltonians.

Ronca E, Li Z, Jimenez-Hoyos CA, Chan GK.

J Chem Theory Comput. 2017 Nov 14;13(11):5560-5571. doi: 10.1021/acs.jctc.7b00682. Epub 2017 Oct 13.

PMID:
28953377
35.

Automated Construction of Molecular Active Spaces from Atomic Valence Orbitals.

Sayfutyarova ER, Sun Q, Chan GK, Knizia G.

J Chem Theory Comput. 2017 Sep 12;13(9):4063-4078. doi: 10.1021/acs.jctc.7b00128. Epub 2017 Aug 29.

PMID:
28731706
37.

Spin-Projected Matrix Product States: Versatile Tool for Strongly Correlated Systems.

Li Z, Chan GK.

J Chem Theory Comput. 2017 Jun 13;13(6):2681-2695. doi: 10.1021/acs.jctc.7b00270. Epub 2017 May 16.

PMID:
28467847
38.

Balancing the Training of Future Cardiologists With the Provision of Team-Based Care.

Fernandes SM, Larsen RL, Chan GK.

JAMA Cardiol. 2017 Jun 1;2(6):589-590. doi: 10.1001/jamacardio.2017.0555. No abstract available.

PMID:
28467549
39.

Gaussian-Based Coupled-Cluster Theory for the Ground-State and Band Structure of Solids.

McClain J, Sun Q, Chan GK, Berkelbach TC.

J Chem Theory Comput. 2017 Mar 14;13(3):1209-1218. doi: 10.1021/acs.jctc.7b00049. Epub 2017 Mar 1.

PMID:
28218843
40.

Trauma advanced practice provider programme development in an academic setting to optimize care coordination.

Woodfall MC, Browder TD, Alfaro JM, Claudius MA, Chan GK, Robinson DG, Spain DA.

Trauma Surg Acute Care Open. 2017 Jan 27;2(1):e000068. doi: 10.1136/tsaco-2016-000068. eCollection 2017.

41.

Atomization of High-Viscosity Fluids for Aromatherapy Using Micro-heaters for Heterogeneous Bubble Nucleation.

Law J, Kong KW, Chan HY, Sun W, Li WJ, Chau EB, Chan GK.

Sci Rep. 2017 Jan 11;7:40289. doi: 10.1038/srep40289.

42.

Quantum Embedding Theories.

Sun Q, Chan GK.

Acc Chem Res. 2016 Dec 20;49(12):2705-2712. Epub 2016 Nov 7.

PMID:
27993005
43.

Authentication of Acori Tatarinowii Rhizoma (Shi Chang Pu) and its adulterants by morphological distinction, chemical composition and ITS sequencing.

Lam KY, Ku CF, Wang HY, Chan GK, Yao P, Lin HQ, Dong TT, Zhang HJ, Tsim KW.

Chin Med. 2016 Sep 26;11:41. eCollection 2016.

44.

From plane waves to local Gaussians for the simulation of correlated periodic systems.

Booth GH, Tsatsoulis T, Chan GK, Grüneis A.

J Chem Phys. 2016 Aug 28;145(8):084111. doi: 10.1063/1.4961301.

PMID:
27586908
45.

Yu Ping Feng San reverses cisplatin-induced multi-drug resistance in lung cancer cells via regulating drug transporters and p62/TRAF6 signalling.

Lou JS, Yan L, Bi CW, Chan GK, Wu QY, Liu YL, Huang Y, Yao P, Du CY, Dong TT, Tsim KW.

Sci Rep. 2016 Aug 25;6:31926. doi: 10.1038/srep31926.

46.

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.

Lim SP, Noble CG, Seh CC, Soh TS, El Sahili A, Chan GK, Lescar J, Arora R, Benson T, Nilar S, Manjunatha U, Wan KF, Dong H, Xie X, Shi PY, Yokokawa F.

PLoS Pathog. 2016 Aug 8;12(8):e1005737. doi: 10.1371/journal.ppat.1005737. eCollection 2016 Aug.

47.

Indication of nerve growth factor binding components from herbal extracts by HerboChip: a platform for drug screening on a chip.

Lee PS, Zhang LM, Yan AL, Lam KY, Dong TT, Lin H, Chan GK, Tsim KW.

Chin Med. 2016 Jul 23;11:34. doi: 10.1186/s13020-016-0107-8. eCollection 2016.

48.

Matrix product operators, matrix product states, and ab initio density matrix renormalization group algorithms.

Chan GK, Keselman A, Nakatani N, Li Z, White SR.

J Chem Phys. 2016 Jul 7;145(1):014102. doi: 10.1063/1.4955108.

PMID:
27394094
49.

Clivorine, an otonecine pyrrolizidine alkaloid from Ligularia species, impairs neuronal differentiation via NGF-induced signaling pathway in cultured PC12 cells.

Xiong A, Yan AL, Bi CW, Lam KY, Chan GK, Lau KK, Dong TT, Lin H, Yang L, Wang Z, Tsim KW.

Phytomedicine. 2016 Aug 15;23(9):931-8. doi: 10.1016/j.phymed.2016.06.006. Epub 2016 Jun 10.

PMID:
27387401
50.

A state interaction spin-orbit coupling density matrix renormalization group method.

Sayfutyarova ER, Chan GK.

J Chem Phys. 2016 Jun 21;144(23):234301. doi: 10.1063/1.4953445.

PMID:
27334156

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