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Items: 31


Risky business: linking Toxoplasma gondii infection and entrepreneurship behaviours across individuals and countries.

Johnson SK, Fitza MA, Lerner DA, Calhoun DM, Beldon MA, Chan ET, Johnson PTJ.

Proc Biol Sci. 2018 Jul 25;285(1883). pii: 20180822. doi: 10.1098/rspb.2018.0822.


Prevention of data duplication for high throughput sequencing repositories.

Gabdank I, Chan ET, Davidson JM, Hilton JA, Davis CA, Baymuradov UK, Narayanan A, Onate KC, Graham K, Miyasato SR, Dreszer TR, Strattan JS, Jolanki O, Tanaka FY, Hitz BC, Sloan CA, Cherry JM.

Database (Oxford). 2018 Jan 1;2018. doi: 10.1093/database/bay008.


Inductive modulation of tris(phosphinomethyl)phenylborate donation at group VI metals via borate phenyl substituent modification.

Fischer PJ, Senthil S, Stephan JT, Swift ML, Storlie MD, Chan ET, Vollmer MV, Young VG.

Dalton Trans. 2018 May 1;47(17):6166-6176. doi: 10.1039/c8dt00703a.


The Encyclopedia of DNA elements (ENCODE): data portal update.

Davis CA, Hitz BC, Sloan CA, Chan ET, Davidson JM, Gabdank I, Hilton JA, Jain K, Baymuradov UK, Narayanan AK, Onate KC, Graham K, Miyasato SR, Dreszer TR, Strattan JS, Jolanki O, Tanaka FY, Cherry JM.

Nucleic Acids Res. 2018 Jan 4;46(D1):D794-D801. doi: 10.1093/nar/gkx1081.


SnoVault and encodeD: A novel object-based storage system and applications to ENCODE metadata.

Hitz BC, Rowe LD, Podduturi NR, Glick DI, Baymuradov UK, Malladi VS, Chan ET, Davidson JM, Gabdank I, Narayana AK, Onate KC, Hilton J, Ho MC, Lee BT, Miyasato SR, Dreszer TR, Sloan CA, Strattan JS, Tanaka FY, Hong EL, Cherry JM.

PLoS One. 2017 Apr 12;12(4):e0175310. doi: 10.1371/journal.pone.0175310. eCollection 2017.


Principles of metadata organization at the ENCODE data coordination center.

Hong EL, Sloan CA, Chan ET, Davidson JM, Malladi VS, Strattan JS, Hitz BC, Gabdank I, Narayanan AK, Ho M, Lee BT, Rowe LD, Dreszer TR, Roe GR, Podduturi NR, Tanaka F, Hilton JA, Cherry JM.

Database (Oxford). 2016 Mar 15;2016. pii: baw001. doi: 10.1093/database/baw001. Print 2016.


ENCODE data at the ENCODE portal.

Sloan CA, Chan ET, Davidson JM, Malladi VS, Strattan JS, Hitz BC, Gabdank I, Narayanan AK, Ho M, Lee BT, Rowe LD, Dreszer TR, Roe G, Podduturi NR, Tanaka F, Hong EL, Cherry JM.

Nucleic Acids Res. 2016 Jan 4;44(D1):D726-32. doi: 10.1093/nar/gkv1160. Epub 2015 Nov 2.


Ontology application and use at the ENCODE DCC.

Malladi VS, Erickson DT, Podduturi NR, Rowe LD, Chan ET, Davidson JM, Hitz BC, Ho M, Lee BT, Miyasato S, Roe GR, Simison M, Sloan CA, Strattan JS, Tanaka F, Kent WJ, Cherry JM, Hong EL.

Database (Oxford). 2015 Mar 16;2015. pii: bav010. doi: 10.1093/database/bav010. Print 2015. Review.


Synergistic effects of proteasome inhibitor carfilzomib in combination with tyrosine kinase inhibitors in imatinib-sensitive and -resistant chronic myeloid leukemia models.

Crawford LJ, Chan ET, Aujay M, Holyoake TL, Melo JV, Jorgensen HG, Suresh S, Walker B, Irvine AE.

Oncogenesis. 2014 Mar 3;3:e90. doi: 10.1038/oncsis.2014.3.


Saccharomyces genome database provides new regulation data.

Costanzo MC, Engel SR, Wong ED, Lloyd P, Karra K, Chan ET, Weng S, Paskov KM, Roe GR, Binkley G, Hitz BC, Cherry JM.

Nucleic Acids Res. 2014 Jan;42(Database issue):D717-25. doi: 10.1093/nar/gkt1158. Epub 2013 Nov 21.


Reactive glia show increased immunoproteasome activity in Alzheimer's disease.

Orre M, Kamphuis W, Dooves S, Kooijman L, Chan ET, Kirk CJ, Dimayuga Smith V, Koot S, Mamber C, Jansen AH, Ovaa H, Hol EM.

Brain. 2013 May;136(Pt 5):1415-31. doi: 10.1093/brain/awt083. Epub 2013 Apr 19.


Overcoming bortezomib resistance in human B cells by anti-CD20/rituximab-mediated complement-dependent cytotoxicity and epoxyketone-based irreversible proteasome inhibitors.

Verbrugge SE, Al M, Assaraf YG, Niewerth D, van Meerloo J, Cloos J, van der Veer M, Scheffer GL, Peters GJ, Chan ET, Anderl JL, Kirk CJ, Zweegman S, Dijkmans BA, Lems WF, Scheper RJ, de Gruijl TD, Jansen G.

Exp Hematol Oncol. 2013 Jan 10;2(1):2. doi: 10.1186/2162-3619-2-2.


The next generation proteasome inhibitors carfilzomib and oprozomib activate prosurvival autophagy via induction of the unfolded protein response and ATF4.

Zang Y, Thomas SM, Chan ET, Kirk CJ, Freilino ML, DeLancey HM, Grandis JR, Li C, Johnson DE.

Autophagy. 2012 Dec;8(12):1873-4. doi: 10.4161/auto.22185. Epub 2012 Sep 20.


Carfilzomib and ONX 0912 inhibit cell survival and tumor growth of head and neck cancer and their activities are enhanced by suppression of Mcl-1 or autophagy.

Zang Y, Thomas SM, Chan ET, Kirk CJ, Freilino ML, DeLancey HM, Grandis JR, Li C, Johnson DE.

Clin Cancer Res. 2012 Oct 15;18(20):5639-49. doi: 10.1158/1078-0432.CCR-12-1213. Epub 2012 Aug 28.


Considerations for creating and annotating the budding yeast Genome Map at SGD: a progress report.

Chan ET, Cherry JM.

Database (Oxford). 2012 Mar 20;2012:bar057. doi: 10.1093/database/bar057. Print 2012.


Inactivating PSMB5 mutations and P-glycoprotein (multidrug resistance-associated protein/ATP-binding cassette B1) mediate resistance to proteasome inhibitors: ex vivo efficacy of (immuno)proteasome inhibitors in mononuclear blood cells from patients with rheumatoid arthritis.

Verbrugge SE, Assaraf YG, Dijkmans BA, Scheffer GL, Al M, den Uyl D, Oerlemans R, Chan ET, Kirk CJ, Peters GJ, van der Heijden JW, de Gruijl TD, Scheper RJ, Jansen G.

J Pharmacol Exp Ther. 2012 Apr;341(1):174-82. doi: 10.1124/jpet.111.187542. Epub 2012 Jan 10.


Saccharomyces Genome Database: the genomics resource of budding yeast.

Cherry JM, Hong EL, Amundsen C, Balakrishnan R, Binkley G, Chan ET, Christie KR, Costanzo MC, Dwight SS, Engel SR, Fisk DG, Hirschman JE, Hitz BC, Karra K, Krieger CJ, Miyasato SR, Nash RS, Park J, Skrzypek MS, Simison M, Weng S, Wong ED.

Nucleic Acids Res. 2012 Jan;40(Database issue):D700-5. doi: 10.1093/nar/gkr1029. Epub 2011 Nov 21.


Proteasome-based mechanisms of intrinsic and acquired bortezomib resistance in non-small cell lung cancer.

de Wilt LH, Jansen G, Assaraf YG, van Meerloo J, Cloos J, Schimmer AD, Chan ET, Kirk CJ, Peters GJ, Kruyt FA.

Biochem Pharmacol. 2012 Jan 15;83(2):207-17. doi: 10.1016/j.bcp.2011.10.009. Epub 2011 Oct 18.


Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells.

Franke NE, Niewerth D, Assaraf YG, van Meerloo J, Vojtekova K, van Zantwijk CH, Zweegman S, Chan ET, Kirk CJ, Geerke DP, Schimmer AD, Kaspers GJ, Jansen G, Cloos J.

Leukemia. 2012 Apr;26(4):757-68. doi: 10.1038/leu.2011.256. Epub 2011 Sep 23.


RNAcontext: a new method for learning the sequence and structure binding preferences of RNA-binding proteins.

Kazan H, Ray D, Chan ET, Hughes TR, Morris Q.

PLoS Comput Biol. 2010 Jul 1;6:e1000832. doi: 10.1371/journal.pcbi.1000832.


Conservation and regulatory associations of a wide affinity range of mouse transcription factor binding sites.

Jaeger SA, Chan ET, Berger MF, Stottmann R, Hughes TR, Bulyk ML.

Genomics. 2010 Apr;95(4):185-95. doi: 10.1016/j.ygeno.2010.01.002. Epub 2010 Jan 15.


Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins.

Ray D, Kazan H, Chan ET, Peña Castillo L, Chaudhry S, Talukder S, Blencowe BJ, Morris Q, Hughes TR.

Nat Biotechnol. 2009 Jul;27(7):667-70. doi: 10.1038/nbt.1550. Epub 2009 Jun 28.


Diversity and complexity in DNA recognition by transcription factors.

Badis G, Berger MF, Philippakis AA, Talukder S, Gehrke AR, Jaeger SA, Chan ET, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang CF, Coburn D, Newburger DE, Morris Q, Hughes TR, Bulyk ML.

Science. 2009 Jun 26;324(5935):1720-3. doi: 10.1126/science.1162327. Epub 2009 May 14.


Conservation of core gene expression in vertebrate tissues.

Chan ET, Quon GT, Chua G, Babak T, Trochesset M, Zirngibl RA, Aubin J, Ratcliffe MJ, Wilde A, Brudno M, Morris QD, Hughes TR.

J Biol. 2009;8(3):33. doi: 10.1186/jbiol130. Epub 2009 Apr 16.


A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters.

Badis G, Chan ET, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson CD, Gossett AJ, Hasinoff MJ, Warren CL, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo ZX, Clarke ND, Lieb JD, Ansari AZ, Nislow C, Hughes TR.

Mol Cell. 2008 Dec 26;32(6):878-87. doi: 10.1016/j.molcel.2008.11.020.


Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences.

Berger MF, Badis G, Gehrke AR, Talukder S, Philippakis AA, Peña-Castillo L, Alleyne TM, Mnaimneh S, Botvinnik OB, Chan ET, Khalid F, Zhang W, Newburger D, Jaeger SA, Morris QD, Bulyk ML, Hughes TR.

Cell. 2008 Jun 27;133(7):1266-76. doi: 10.1016/j.cell.2008.05.024.


Identifying transcription factor functions and targets by phenotypic activation.

Chua G, Morris QD, Sopko R, Robinson MD, Ryan O, Chan ET, Frey BJ, Andrews BJ, Boone C, Hughes TR.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12045-50. Epub 2006 Jul 31.


Toward implementation of a regional quality assurance program in cytopathology: the Hong Kong experience.

Ng WK, Chiu CS, Cheng Y, Chan ET, Chiu FL, Collins RJ; Cytology Quality Assurance Program Working Group, Hong Kong College of Pathologists.

Acta Cytol. 2006 Mar-Apr;50(2):164-77.


Diffusion tensor imaging (DTI) of rodent brains in vivo using a 1.5T clinical MR scanner.

Lee FK, Fang MR, Antonio GE, Yeung DK, Chan ET, Zhang LH, Yew DT, Ahuja AT.

J Magn Reson Imaging. 2006 May;23(5):747-51.


Zonal distribution of cysteine uptake in the perfused rat liver.

Saiki H, Chan ET, Wong E, Yamamuro W, Ookhtens M, Kaplowitz N.

J Biol Chem. 1992 Jan 5;267(1):192-6.


Effect of phorone and allopurinol on ischemia-reperfusion injury in gastrointestinal mucosa of the rat.

Yasue N, Chan ET, Kaplowitz N, Guth PH.

Pharmacology. 1992;44(6):334-43.


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