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Items: 1 to 50 of 85

1.

WRN helicase is a synthetic lethal target in microsatellite unstable cancers.

Chan EM, Shibue T, McFarland JM, Gaeta B, Ghandi M, Dumont N, Gonzalez A, McPartlan JS, Li T, Zhang Y, Bin Liu J, Lazaro JB, Gu P, Piett CG, Apffel A, Ali SO, Deasy R, Keskula P, Ng RWS, Roberts EA, Reznichenko E, Leung L, Alimova M, Schenone M, Islam M, Maruvka YE, Liu Y, Roper J, Raghavan S, Giannakis M, Tseng YY, Nagel ZD, D'Andrea A, Root DE, Boehm JS, Getz G, Chang S, Golub TR, Tsherniak A, Vazquez F, Bass AJ.

Nature. 2019 Apr;568(7753):551-556. doi: 10.1038/s41586-019-1102-x. Epub 2019 Apr 10.

PMID:
30971823
2.

MoS2 Liquid Cell Electron Microscopy Through Clean and Fast Polymer-Free MoS2 Transfer.

Yang J, Choi MK, Sheng Y, Jung J, Bustillo K, Chen T, Lee SW, Ercius P, Kim JH, Warner JH, Chan EM, Zheng H.

Nano Lett. 2019 Mar 13;19(3):1788-1795. doi: 10.1021/acs.nanolett.8b04821. Epub 2019 Feb 14.

PMID:
30741548
3.

Upconverting nanoparticle micro-lightbulbs designed for deep tissue optical stimulation and imaging.

Chamanzar M, Garfield DJ, Iafrati J, Chan EM, Sohal V, Cohen BE, Schuck PJ, Maharbiz MM.

Biomed Opt Express. 2018 Aug 20;9(9):4359-4371. doi: 10.1364/BOE.9.004359. eCollection 2018 Sep 1.

4.

Evaluation of "Colorful Life": A Multi-Addiction Expressive Arts Intervention Program for Adolescents of Addicted Parents and Parents with Addiction.

Leung H, Shek DTL, Yu L, Wu FKY, Law MYM, Chan EML, Lo CKM.

Int J Ment Health Addict. 2018;16(6):1343-1356. doi: 10.1007/s11469-018-9899-3. Epub 2018 Jun 5.

5.

Apparent self-heating of individual upconverting nanoparticle thermometers.

Pickel AD, Teitelboim A, Chan EM, Borys NJ, Schuck PJ, Dames C.

Nat Commun. 2018 Nov 21;9(1):4907. doi: 10.1038/s41467-018-07361-0.

6.

Dynamics of Nanoscale Dendrite Formation in Solution Growth Revealed Through in Situ Liquid Cell Electron Microscopy.

Hauwiller MR, Zhang X, Liang WI, Chiu CH, Zhang Q, Zheng W, Ophus C, Chan EM, Czarnik C, Pan M, Ross FM, Wu WW, Chu YH, Asta M, Voorhees PW, Alivisatos AP, Zheng H.

Nano Lett. 2018 Oct 10;18(10):6427-6433. doi: 10.1021/acs.nanolett.8b02819. Epub 2018 Sep 28.

PMID:
30256644
7.

Low irradiance multiphoton imaging with alloyed lanthanide nanocrystals.

Tian B, Fernandez-Bravo A, Najafiaghdam H, Torquato NA, Altoe MVP, Teitelboim A, Tajon CA, Tian Y, Borys NJ, Barnard ES, Anwar M, Chan EM, Schuck PJ, Cohen BE.

Nat Commun. 2018 Aug 6;9(1):3082. doi: 10.1038/s41467-018-05577-8.

8.

Facile transformation of imine covalent organic frameworks into ultrastable crystalline porous aromatic frameworks.

Li X, Zhang C, Cai S, Lei X, Altoe V, Hong F, Urban JJ, Ciston J, Chan EM, Liu Y.

Nat Commun. 2018 Jul 31;9(1):2998. doi: 10.1038/s41467-018-05462-4.

9.

Including gaming disorder in the ICD-11: The need to do so from a clinical and public health perspective.

Rumpf HJ, Achab S, Billieux J, Bowden-Jones H, Carragher N, Demetrovics Z, Higuchi S, King DL, Mann K, Potenza M, Saunders JB, Abbott M, Ambekar A, Aricak OT, Assanangkornchai S, Bahar N, Borges G, Brand M, Chan EM, Chung T, Derevensky J, Kashef AE, Farrell M, Fineberg NA, Gandin C, Gentile DA, Griffiths MD, Goudriaan AE, Grall-Bronnec M, Hao W, Hodgins DC, Ip P, Király O, Lee HK, Kuss D, Lemmens JS, Long J, Lopez-Fernandez O, Mihara S, Petry NM, Pontes HM, Rahimi-Movaghar A, Rehbein F, Rehm J, Scafato E, Sharma M, Spritzer D, Stein DJ, Tam P, Weinstein A, Wittchen HU, Wölfling K, Zullino D, Poznyak V.

J Behav Addict. 2018 Sep 1;7(3):556-561. doi: 10.1556/2006.7.2018.59. Epub 2018 Jul 16.

10.

Effectiveness of a multidisciplinary approach to geriatric hip fractures in improving clinical outcomes and cost of care.

Leung FK, Lau TW, Yuen GW, Chan EM, Chan P, Lam RY.

Hong Kong Med J. 2018 Feb;24 Suppl 2(1):45-47. No abstract available.

11.

Continuous-wave upconverting nanoparticle microlasers.

Fernandez-Bravo A, Yao K, Barnard ES, Borys NJ, Levy ES, Tian B, Tajon CA, Moretti L, Altoe MV, Aloni S, Beketayev K, Scotognella F, Cohen BE, Chan EM, Schuck PJ.

Nat Nanotechnol. 2018 Jul;13(7):572-577. doi: 10.1038/s41565-018-0161-8. Epub 2018 Jun 18.

PMID:
29915271
12.

Macrophage-mediated delivery of light activated nitric oxide prodrugs with spatial, temporal and concentration control.

Evans MA, Huang PJ, Iwamoto Y, Ibsen KN, Chan EM, Hitomi Y, Ford PC, Mitragotri S.

Chem Sci. 2018 Mar 16;9(15):3729-3741. doi: 10.1039/c8sc00015h. eCollection 2018 Apr 21.

13.

The Making and Breaking of Lead-Free Double Perovskite Nanocrystals of Cesium Silver-Bismuth Halide Compositions.

Bekenstein Y, Dahl JC, Huang J, Osowiecki WT, Swabeck JK, Chan EM, Yang P, Alivisatos AP.

Nano Lett. 2018 Jun 13;18(6):3502-3508. doi: 10.1021/acs.nanolett.8b00560. Epub 2018 May 7.

PMID:
29719146
14.

Accessing valley degree of freedom in bulk Tin(II) sulfide at room temperature.

Lin S, Carvalho A, Yan S, Li R, Kim S, Rodin A, Carvalho L, Chan EM, Wang X, Castro Neto AH, Yao J.

Nat Commun. 2018 Apr 13;9(1):1455. doi: 10.1038/s41467-018-03897-3.

15.

Phase 1 and pharmacokinetic study of LY3007113, a p38 MAPK inhibitor, in patients with advanced cancer.

Goldman JW, Rosen LS, Tolcher AW, Papadopoulos K, Beeram M, Shi P, Pitou C, Bell R, Kulanthaivel P, Zhang X, Fink A, Chan EM, Shahir A, Farrington D, Patnaik A.

Invest New Drugs. 2018 Aug;36(4):629-637. doi: 10.1007/s10637-017-0532-2. Epub 2017 Dec 1.

16.

Multifunctional Magnetic and Upconverting Nanobeads as Dual Modal Imaging Tools.

Materia ME, Pernia Leal M, Scotto M, Balakrishnan PB, Kumar Avugadda S, García-Martín ML, Cohen BE, Chan EM, Pellegrino T.

Bioconjug Chem. 2017 Nov 15;28(11):2707-2714. doi: 10.1021/acs.bioconjchem.7b00432. Epub 2017 Nov 2.

17.
18.

A Population Pharmacokinetic and Pharmacodynamic Analysis of Abemaciclib in a Phase I Clinical Trial in Cancer Patients.

Tate SC, Sykes AK, Kulanthaivel P, Chan EM, Turner PK, Cronier DM.

Clin Pharmacokinet. 2018 Mar;57(3):335-344. doi: 10.1007/s40262-017-0559-8.

19.

Direct Evidence for Coupled Surface and Concentration Quenching Dynamics in Lanthanide-Doped Nanocrystals.

Johnson NJ, He S, Diao S, Chan EM, Dai H, Almutairi A.

J Am Chem Soc. 2017 Mar 1;139(8):3275-3282. doi: 10.1021/jacs.7b00223. Epub 2017 Feb 17.

PMID:
28169535
20.

Precise Tuning of Surface Quenching for Luminescence Enhancement in Core-Shell Lanthanide-Doped Nanocrystals.

Fischer S, Bronstein ND, Swabeck JK, Chan EM, Alivisatos AP.

Nano Lett. 2016 Nov 9;16(11):7241-7247. Epub 2016 Oct 13.

PMID:
27726405
21.

Gambling related family coping and the impact of problem gambling on families in Hong Kong.

Chan EM, Dowling NA, Jackson AC, Shek DT.

Asian J Gambl Issues Public Health. 2016;6(1):1. Epub 2016 Mar 31.

22.

Energy-Looping Nanoparticles: Harnessing Excited-State Absorption for Deep-Tissue Imaging.

Levy ES, Tajon CA, Bischof TS, Iafrati J, Fernandez-Bravo A, Garfield DJ, Chamanzar M, Maharbiz MM, Sohal VS, Schuck PJ, Cohen BE, Chan EM.

ACS Nano. 2016 Sep 27;10(9):8423-33. doi: 10.1021/acsnano.6b03288. Epub 2016 Sep 7.

PMID:
27603228
23.

Phase 1 study of abemaciclib, an inhibitor of CDK 4 and 6, as a single agent for Japanese patients with advanced cancer.

Fujiwara Y, Tamura K, Kondo S, Tanabe Y, Iwasa S, Shimomura A, Kitano S, Ogasawara K, Turner PK, Mori J, Asou H, Chan EM, Yamamoto N.

Cancer Chemother Pharmacol. 2016 Aug;78(2):281-8. doi: 10.1007/s00280-016-3085-8. Epub 2016 Jun 16.

PMID:
27312735
24.

Efficacy and Safety of Abemaciclib, an Inhibitor of CDK4 and CDK6, for Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Other Solid Tumors.

Patnaik A, Rosen LS, Tolaney SM, Tolcher AW, Goldman JW, Gandhi L, Papadopoulos KP, Beeram M, Rasco DW, Hilton JF, Nasir A, Beckmann RP, Schade AE, Fulford AD, Nguyen TS, Martinez R, Kulanthaivel P, Li LQ, Frenzel M, Cronier DM, Chan EM, Flaherty KT, Wen PY, Shapiro GI.

Cancer Discov. 2016 Jul;6(7):740-53. doi: 10.1158/2159-8290.CD-16-0095. Epub 2016 May 23.

25.

Far-field optical nanothermometry using individual sub-50 nm upconverting nanoparticles.

Kilbane JD, Chan EM, Monachon C, Borys NJ, Levy ES, Pickel AD, Urban JJ, Schuck PJ, Dames C.

Nanoscale. 2016 Jun 2;8(22):11611-6. doi: 10.1039/c6nr01479h.

PMID:
27216164
26.

A first-in-human phase I study of the oral Notch inhibitor, LY900009, in patients with advanced cancer.

Pant S, Jones SF, Kurkjian CD, Infante JR, Moore KN, Burris HA, McMeekin DS, Benhadji KA, Patel BKR, Frenzel MJ, Kursar JD, Zamek-Gliszczynski MJ, Yuen ESM, Chan EM, Bendell JC.

Eur J Cancer. 2016 Mar;56:1-9. doi: 10.1016/j.ejca.2015.11.021. Epub 2016 Jan 19.

27.

Dye-Sensitized Core/Active Shell Upconversion Nanoparticles for Optogenetics and Bioimaging Applications.

Wu X, Zhang Y, Takle K, Bilsel O, Li Z, Lee H, Zhang Z, Li D, Fan W, Duan C, Chan EM, Lois C, Xiang Y, Han G.

ACS Nano. 2016 Jan 26;10(1):1060-6. doi: 10.1021/acsnano.5b06383. Epub 2016 Jan 11.

28.

A First-in-Human Phase I Study of the Oral p38 MAPK Inhibitor, Ralimetinib (LY2228820 Dimesylate), in Patients with Advanced Cancer.

Patnaik A, Haluska P, Tolcher AW, Erlichman C, Papadopoulos KP, Lensing JL, Beeram M, Molina JR, Rasco DW, Arcos RR, Kelly CS, Wijayawardana SR, Zhang X, Stancato LF, Bell R, Shi P, Kulanthaivel P, Pitou C, Mulle LB, Farrington DL, Chan EM, Goetz MP.

Clin Cancer Res. 2016 Mar 1;22(5):1095-102. doi: 10.1158/1078-0432.CCR-15-1718. Epub 2015 Nov 18. Erratum in: Clin Cancer Res. 2016 May 15;22(10 ):2596.

29.

Rationally Designed Energy Transfer in Upconverting Nanoparticles.

Chan EM, Levy ES, Cohen BE.

Adv Mater. 2015 Oct 14;27(38):5753-61. doi: 10.1002/adma.201500248. Epub 2015 Mar 24.

PMID:
25809982
30.

Amplifying the red-emission of upconverting nanoparticles for biocompatible clinically used prodrug-induced photodynamic therapy.

Punjabi A, Wu X, Tokatli-Apollon A, El-Rifai M, Lee H, Zhang Y, Wang C, Liu Z, Chan EM, Duan C, Han G.

ACS Nano. 2014 Oct 28;8(10):10621-30. doi: 10.1021/nn505051d. Epub 2014 Oct 7.

31.
32.

The CDK4/6 inhibitor LY2835219 overcomes vemurafenib resistance resulting from MAPK reactivation and cyclin D1 upregulation.

Yadav V, Burke TF, Huber L, Van Horn RD, Zhang Y, Buchanan SG, Chan EM, Starling JJ, Beckmann RP, Peng SB.

Mol Cancer Ther. 2014 Oct;13(10):2253-63. doi: 10.1158/1535-7163.MCT-14-0257. Epub 2014 Aug 13.

33.

Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine.

Gelbert LM, Cai S, Lin X, Sanchez-Martinez C, Del Prado M, Lallena MJ, Torres R, Ajamie RT, Wishart GN, Flack RS, Neubauer BL, Young J, Chan EM, Iversen P, Cronier D, Kreklau E, de Dios A.

Invest New Drugs. 2014 Oct;32(5):825-37. doi: 10.1007/s10637-014-0120-7. Epub 2014 Jun 13.

34.

Semi-mechanistic pharmacokinetic/pharmacodynamic modeling of the antitumor activity of LY2835219, a new cyclin-dependent kinase 4/6 inhibitor, in mice bearing human tumor xenografts.

Tate SC, Cai S, Ajamie RT, Burke T, Beckmann RP, Chan EM, De Dios A, Wishart GN, Gelbert LM, Cronier DM.

Clin Cancer Res. 2014 Jul 15;20(14):3763-74. doi: 10.1158/1078-0432.CCR-13-2846. Epub 2014 May 21.

35.

Engineering bright sub-10-nm upconverting nanocrystals for single-molecule imaging.

Gargas DJ, Chan EM, Ostrowski AD, Aloni S, Altoe MV, Barnard ES, Sanii B, Urban JJ, Milliron DJ, Cohen BE, Schuck PJ.

Nat Nanotechnol. 2014 Apr;9(4):300-5. doi: 10.1038/nnano.2014.29. Epub 2014 Mar 16.

PMID:
24633523
36.

Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.

Zhu Z, Aref AR, Cohoon TJ, Barbie TU, Imamura Y, Yang S, Moody SE, Shen RR, Schinzel AC, Thai TC, Reibel JB, Tamayo P, Godfrey JT, Qian ZR, Page AN, Maciag K, Chan EM, Silkworth W, Labowsky MT, Rozhansky L, Mesirov JP, Gillanders WE, Ogino S, Hacohen N, Gaudet S, Eck MJ, Engelman JA, Corcoran RB, Wong KK, Hahn WC, Barbie DA.

Cancer Discov. 2014 Apr;4(4):452-65. doi: 10.1158/2159-8290.CD-13-0646. Epub 2014 Jan 20.

37.

Characterization of LY2228820 dimesylate, a potent and selective inhibitor of p38 MAPK with antitumor activity.

Campbell RM, Anderson BD, Brooks NA, Brooks HB, Chan EM, De Dios A, Gilmour R, Graff JR, Jambrina E, Mader M, McCann D, Na S, Parsons SH, Pratt SE, Shih C, Stancato LF, Starling JJ, Tate C, Velasco JA, Wang Y, Ye XS.

Mol Cancer Ther. 2014 Feb;13(2):364-74. doi: 10.1158/1535-7163.MCT-13-0513. Epub 2013 Dec 19.

38.

Ultralow thermal conductivity in polycrystalline CdSe thin films with controlled grain size.

Feser JP, Chan EM, Majumdar A, Segalman RA, Urban JJ.

Nano Lett. 2013 May 8;13(5):2122-7. doi: 10.1021/nl400531f. Epub 2013 Apr 29.

PMID:
23617743
39.

Early-onset Lafora body disease.

Turnbull J, Girard JM, Lohi H, Chan EM, Wang P, Tiberia E, Omer S, Ahmed M, Bennett C, Chakrabarty A, Tyagi A, Liu Y, Pencea N, Zhao X, Scherer SW, Ackerley CA, Minassian BA.

Brain. 2012 Sep;135(Pt 9):2684-98. doi: 10.1093/brain/aws205.

40.

Quantum dot photoluminescence quenching by Cr(III) complexes. Photosensitized reactions and evidence for a FRET mechanism.

Burks PT, Ostrowski AD, Mikhailovsky AA, Chan EM, Wagenknecht PS, Ford PC.

J Am Chem Soc. 2012 Aug 15;134(32):13266-75. doi: 10.1021/ja300771w. Epub 2012 Aug 1.

PMID:
22808899
41.

Associations between pathological gambling and psychiatric comorbidity among help-seeking populations in Hong Kong.

Shek DT, Chan EM, Wong RH.

ScientificWorldJournal. 2012;2012:571434. doi: 10.1100/2012/571434. Epub 2012 Jun 18.

42.

Combinatorial discovery of lanthanide-doped nanocrystals with spectrally pure upconverted emission.

Chan EM, Han G, Goldberg JD, Gargas DJ, Ostrowski AD, Schuck PJ, Cohen BE, Milliron DJ.

Nano Lett. 2012 Jul 11;12(7):3839-45. doi: 10.1021/nl3017994. Epub 2012 Jun 19.

PMID:
22713101
43.

Dual-emitting quantum dot/quantum rod-based nanothermometers with enhanced response and sensitivity in live cells.

Albers AE, Chan EM, McBride PM, Ajo-Franklin CM, Cohen BE, Helms BA.

J Am Chem Soc. 2012 Jun 13;134(23):9565-8. doi: 10.1021/ja302290e. Epub 2012 Jun 1.

PMID:
22642769
44.

Concentrating and recycling energy in lanthanide codopants for efficient and spectrally pure emission: the case of NaYF4:Er3+/Tm3+ upconverting nanocrystals.

Chan EM, Gargas DJ, Schuck PJ, Milliron DJ.

J Phys Chem B. 2012 Sep 6;116(35):10561-70. doi: 10.1021/jp302401j. Epub 2012 May 14.

PMID:
22551408
45.

Controlled synthesis and single-particle imaging of bright, sub-10 nm lanthanide-doped upconverting nanocrystals.

Ostrowski AD, Chan EM, Gargas DJ, Katz EM, Han G, Schuck PJ, Milliron DJ, Cohen BE.

ACS Nano. 2012 Mar 27;6(3):2686-92. doi: 10.1021/nn3000737. Epub 2012 Feb 22.

PMID:
22339653
46.

Focusing nanocrystal size distributions via production control.

Clark MD, Kumar SK, Owen JS, Chan EM.

Nano Lett. 2011 May 11;11(5):1976-80. doi: 10.1021/nl200286j. Epub 2011 Apr 8.

PMID:
21476514
47.

Thrice weekly azacitidine does not improve hematological responses in lower-risk myelodysplastic syndromes: a study of the Hoosier Oncology Group.

Sayar H, Chan RJ, Orschell CM, Chan EM, Yu Z, Hood D, Plett A, Yang Z, Hui CL, Nabinger SC, Kohlbacher KJ, West ES, Walter A, Sampson C, Wu J, Cripe LD.

Leuk Res. 2011 Aug;35(8):1108-10. doi: 10.1016/j.leukres.2011.02.025. Epub 2011 Mar 21.

PMID:
21420732
48.

Precursor conversion kinetics and the nucleation of cadmium selenide nanocrystals.

Owen JS, Chan EM, Liu H, Alivisatos AP.

J Am Chem Soc. 2010 Dec 29;132(51):18206-13. doi: 10.1021/ja106777j. Epub 2010 Dec 3.

PMID:
21128655
49.

Hopefulness predicts resilience after hereditary colorectal cancer genetic testing: a prospective outcome trajectories study.

Ho SM, Ho JW, Bonanno GA, Chu AT, Chan EM.

BMC Cancer. 2010 Jun 11;10:279. doi: 10.1186/1471-2407-10-279.

50.

Reproducible, high-throughput synthesis of colloidal nanocrystals for optimization in multidimensional parameter space.

Chan EM, Xu C, Mao AW, Han G, Owen JS, Cohen BE, Milliron DJ.

Nano Lett. 2010 May 12;10(5):1874-85. doi: 10.1021/nl100669s.

PMID:
20387807

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