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Items: 1 to 50 of 80

1.

SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player.

Zakrzewicz A, Richter K, Zakrzewicz D, Siebers K, Damm J, Agné A, Hecker A, McIntosh JM, Chamulitrat W, Krasteva-Christ G, Manzini I, Tikkanen R, Padberg W, Janciauskiene S, Grau V.

Front Immunol. 2019 Apr 4;10:664. doi: 10.3389/fimmu.2019.00664. eCollection 2019.

2.

Group VIA phospholipase A2 deficiency in mice chronically fed with high-fat-diet attenuates hepatic steatosis by correcting a defect of phospholipid remodeling.

Otto AC, Gan-Schreier H, Zhu X, Tuma-Kellner S, Staffer S, Ganzha A, Liebisch G, Chamulitrat W.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May;1864(5):662-676. doi: 10.1016/j.bbalip.2019.01.012. Epub 2019 Feb 5.

PMID:
30735855
3.

iPla2β deficiency in mice fed with MCD diet does not correct the defect of phospholipid remodeling but attenuates hepatocellular injury via an inhibition of lipid uptake genes.

Zhu X, Gan-Schreier H, Otto AC, Cheng Y, Staffer S, Tuma-Kellner S, Ganzha A, Liebisch G, Chamulitrat W.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May;1864(5):677-687. doi: 10.1016/j.bbalip.2019.02.003. Epub 2019 Feb 5.

PMID:
30735854
4.

Elevation of blood lipids in hepatocyte-specific fatty acid transport 4-deficient mice fed with high glucose diets.

Döring S, Seeßle J, Gan-Schreier H, Javaheri B, Jiao L, Cheng Y, Tuma-Kellner S, Liebisch G, Herrmann T, Stremmel W, Chamulitrat W.

Mol Genet Metab. 2019 Jan;126(1):30-38. doi: 10.1016/j.ymgme.2018.11.010. Epub 2018 Nov 23.

PMID:
30497809
5.

Bivalent Ligand UDCA-LPE Inhibits Pro-Fibrogenic Integrin Signalling by Inducing Lipid Raft-Mediated Internalization.

Su J, Gan-Schreier H, Goeppert B, Chamulitrat W, Stremmel W, Pathil A.

Int J Mol Sci. 2018 Oct 20;19(10). pii: E3254. doi: 10.3390/ijms19103254.

6.

Alpha-1 Antitrypsin Inhibits ATP-Mediated Release of Interleukin-1β via CD36 and Nicotinic Acetylcholine Receptors.

Siebers K, Fink B, Zakrzewicz A, Agné A, Richter K, Konzok S, Hecker A, Zukunft S, Küllmar M, Klein J, McIntosh JM, Timm T, Sewald K, Padberg W, Aggarwal N, Chamulitrat W, Santoso S, Xia W, Janciauskiene S, Grau V.

Front Immunol. 2018 Apr 25;9:877. doi: 10.3389/fimmu.2018.00877. eCollection 2018.

7.

Circulating Phospholipid Patterns in NAFLD Patients Associated with a Combination of Metabolic Risk Factors.

Tiwari-Heckler S, Gan-Schreier H, Stremmel W, Chamulitrat W, Pathil A.

Nutrients. 2018 May 21;10(5). pii: E649. doi: 10.3390/nu10050649.

8.

Anti-inflammatory properties of ursodeoxycholyl lysophosphatidylethanolamide in endotoxin-mediated inflammatory liver injury.

Ludwig JM, Zhang Y, Chamulitrat W, Stremmel W, Pathil A.

PLoS One. 2018 May 24;13(5):e0197836. doi: 10.1371/journal.pone.0197836. eCollection 2018.

9.

Diterpenoid trigonoreidon B isolated from Trigonostemon reidioides alleviates inflammation in models of LPS-stimulated murine macrophages and inflammatory liver injury in mice.

Utaipan T, Suksamrarn A, Kaemchantuek P, Chokchaisiri R, Stremmel W, Chamulitrat W, Chunglok W.

Biomed Pharmacother. 2018 May;101:961-971. doi: 10.1016/j.biopha.2018.02.144. Epub 2018 Mar 22.

PMID:
29635906
10.

Ursodeoxycholyl lysophosphatidylethanolamide negatively regulates TLR-mediated lipopolysaccharide response in human THP-1-derived macrophages.

Horvatova A, Utaipan T, Otto AC, Zhang Y, Gan-Schreier H, Pavek P, Pathil A, Stremmel W, Chamulitrat W.

Eur J Pharmacol. 2018 Apr 15;825:63-74. doi: 10.1016/j.ejphar.2018.02.030. Epub 2018 Feb 20.

PMID:
29475064
11.

Ageing sensitized by iPLA2β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids.

Jiao L, Gan-Schreier H, Zhu X, Wei W, Tuma-Kellner S, Liebisch G, Stremmel W, Chamulitrat W.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Dec;1862(12):1520-1533. doi: 10.1016/j.bbalip.2017.09.001. Epub 2017 Sep 6.

PMID:
28888832
12.

Ursodeoxycholyl Lysophosphatidylethanolamide Protects Against CD95/FAS-Induced Fulminant Hepatitis.

Utaipan T, Otto AC, Gan-Schreier H, Chunglok W, Pathil A, Stremmel W, Chamulitrat W.

Shock. 2017 Aug;48(2):251-259. doi: 10.1097/SHK.0000000000000831.

PMID:
28060213
13.

Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor.

Carazo A, Hyrsova L, Dusek J, Chodounska H, Horvatova A, Berka K, Bazgier V, Gan-Schreier H, Chamulitrat W, Kudova E, Pavek P.

Toxicol Lett. 2017 Jan 4;265:86-96. doi: 10.1016/j.toxlet.2016.11.013. Epub 2016 Nov 18.

PMID:
27871908
14.

iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling.

Deng X, Wang J, Jiao L, Utaipan T, Tuma-Kellner S, Schmitz G, Liebisch G, Stremmel W, Chamulitrat W.

Biochim Biophys Acta. 2016 May;1861(5):449-61. doi: 10.1016/j.bbalip.2016.02.004. Epub 2016 Feb 9.

PMID:
26873633
15.

Deficiency of iPLA₂β Primes Immune Cells for Proinflammation: Potential Involvement in Age-Related Mesenteric Lymph Node Lymphoma.

Inhoffen J, Tuma-Kellner S, Straub B, Stremmel W, Chamulitrat W.

Cancers (Basel). 2015 Dec 9;7(4):2427-42. doi: 10.3390/cancers7040901.

16.

Deficiency of Group VIA Phospholipase A2 (iPLA2β) Renders Susceptibility for Chemical-Induced Colitis.

Jiao L, Inhoffen J, Gan-Schreier H, Tuma-Kellner S, Stremmel W, Sun Z, Chamulitrat W.

Dig Dis Sci. 2015 Dec;60(12):3590-602. doi: 10.1007/s10620-015-3807-5. Epub 2015 Jul 17.

PMID:
26182903
17.

Ursodeoxycholyl Lysophosphatidylethanolamide modifies aberrant lipid profiles in NAFLD.

Pathil A, Liebisch G, Okun JG, Chamulitrat W, Schmitz G, Stremmel W.

Eur J Clin Invest. 2015 Sep;45(9):925-31. doi: 10.1111/eci.12486. Epub 2015 Jul 14.

PMID:
26108973
18.

Sensitization to autoimmune hepatitis in group VIA calcium-independent phospholipase A2-null mice led to duodenal villous atrophy with apoptosis, goblet cell hyperplasia and leaked bile acids.

Jiao L, Gan-Schreier H, Tuma-Kellner S, Stremmel W, Chamulitrat W.

Biochim Biophys Acta. 2015 Aug;1852(8):1646-57. doi: 10.1016/j.bbadis.2015.04.025. Epub 2015 May 7.

19.

Palmitate activation by fatty acid transport protein 4 as a model system for hepatocellular apoptosis and steatosis.

Seeßle J, Liebisch G, Schmitz G, Stremmel W, Chamulitrat W.

Biochim Biophys Acta. 2015 May;1851(5):549-65. doi: 10.1016/j.bbalip.2015.01.004. Epub 2015 Jan 17.

PMID:
25603556
20.

Ursodeoxycholyl lysophosphatidylethanolamide protects against hepatic ischemia and reperfusion injury in mice.

Wang J, Deng X, Yi S, Pathil A, Zhang W, Setchell K, Stremmel W, Chamulitrat W.

Shock. 2015 Apr;43(4):379-86. doi: 10.1097/SHK.0000000000000312.

PMID:
25526375
21.

Ursodeoxycholyl lysophosphatidylethanolamide inhibits cholestasis- and hypoxia-induced apoptosis by upregulating antiapoptosis proteins.

Sellinger M, Xu W, Pathil A, Stremmel W, Chamulitrat W.

Exp Biol Med (Maywood). 2015 Feb;240(2):252-60. doi: 10.1177/1535370214547157. Epub 2014 Aug 14.

22.

Ursodeoxycholyl lysophosphatidylethanolamide attenuates hepatofibrogenesis by impairment of TGF-β1/Smad2/3 signalling.

Pathil A, Mueller J, Ludwig JM, Wang J, Warth A, Chamulitrat W, Stremmel W.

Br J Pharmacol. 2014 Nov;171(22):5113-26. doi: 10.1111/bph.12837. Epub 2014 Sep 5.

23.

Plasma membrane phospholipase A2 controls hepatocellular fatty acid uptake and is responsive to pharmacological modulation: implications for nonalcoholic steatohepatitis.

Stremmel W, Staffer S, Wannhoff A, Pathil A, Chamulitrat W.

FASEB J. 2014 Jul;28(7):3159-70. doi: 10.1096/fj.14-249763. Epub 2014 Apr 9.

PMID:
24719358
24.

Study designs to investigate Nox1 acceleration of neoplastic progression in immortalized human epithelial cells by selection of differentiation resistant cells.

Sattayakhom A, Chunglok W, Ittarat W, Chamulitrat W.

Redox Biol. 2013 Dec 21;2:140-7. doi: 10.1016/j.redox.2013.12.010. eCollection 2014. Review.

25.

Ursodeoxycholyl lysophosphatidylethanolamide inhibits lipoapoptosis by shifting fatty acid pools toward monosaturated and polyunsaturated fatty acids in mouse hepatocytes.

Chamulitrat W, Liebisch G, Xu W, Gan-Schreier H, Pathil A, Schmitz G, Stremmel W.

Mol Pharmacol. 2013 Nov;84(5):696-709. doi: 10.1124/mol.113.088039. Epub 2013 Aug 23.

PMID:
23974795
26.

Hepatoprotectant ursodeoxycholyl lysophosphatidylethanolamide increasing phosphatidylcholine levels as a potential therapy of acute liver injury.

Chamulitrat W, Zhang W, Xu W, Pathil A, Setchell K, Stremmel W.

Front Physiol. 2012 Feb 20;3:24. doi: 10.3389/fphys.2012.00024. eCollection 2012.

27.

Role of myocyte enhancing factor 2B in epithelial myofibroblast transition of human gingival keratinocytes.

Sun Q, Sattayakhom A, Backs J, Stremmel W, Chamulitrat W.

Exp Biol Med (Maywood). 2012 Feb;237(2):178-85. doi: 10.1258/ebm.2011.011261. Epub 2012 Feb 2.

PMID:
22302709
28.

Ursodeoxycholyl lysophosphatidylethanolamide improves steatosis and inflammation in murine models of nonalcoholic fatty liver disease.

Pathil A, Mueller J, Warth A, Chamulitrat W, Stremmel W.

Hepatology. 2012 May;55(5):1369-78. doi: 10.1002/hep.25531. Epub 2012 Mar 18.

PMID:
22183915
29.

Redox regulation of cytokeratin 18 protein by NADPH oxidase 1 in preneoplastic human epithelial cells.

Sattayakhom A, Ittiwat W, Stremmel W, Chamulitrat W.

J Cancer Res Clin Oncol. 2011 Nov;137(11):1669-78. doi: 10.1007/s00432-011-1041-x. Epub 2011 Aug 30.

PMID:
21877197
30.

Adipocyte-specific inactivation of Acyl-CoA synthetase fatty acid transport protein 4 (Fatp4) in mice causes adipose hypertrophy and alterations in metabolism of complex lipids under high fat diet.

Lenz LS, Marx J, Chamulitrat W, Kaiser I, Gröne HJ, Liebisch G, Schmitz G, Elsing C, Straub BK, Füllekrug J, Stremmel W, Herrmann T.

J Biol Chem. 2011 Oct 14;286(41):35578-87. doi: 10.1074/jbc.M111.226530. Epub 2011 Jul 31.

31.

Comparison of different bile acid-phospholipid conjugates in acute hepatitis.

Pathil A, Warth A, Chamulitrat W, Stremmel W.

Eur J Clin Invest. 2012 Feb;42(2):130-8. doi: 10.1111/j.1365-2362.2011.02563.x. Epub 2011 Jun 27.

PMID:
21707612
32.

The synthetic bile acid-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide suppresses TNFα-induced liver injury.

Pathil A, Warth A, Chamulitrat W, Stremmel W.

J Hepatol. 2011 Apr;54(4):674-84. doi: 10.1016/j.jhep.2010.07.028. Epub 2010 Sep 27.

PMID:
21146893
33.

Role of gp91phox homolog nox1 in induction of premalignant spindle phenotypes of HPV 16 E6/E7-immortalized human keratinocytes.

Chamulitrat W.

ScientificWorldJournal. 2010 Jul 19;10:1435-49. doi: 10.1100/tsw.2010.131. Review.

34.

Bile salt-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide as a hepatoprotective agent.

Chamulitrat W, Burhenne J, Rehlen T, Pathil A, Stremmel W.

Hepatology. 2009 Jul;50(1):143-54. doi: 10.1002/hep.22955.

PMID:
19496180
35.

Human papillomavirus 16 E6/E7-immortalized human gingival keratinocytes with epithelial mesenchymal transition acquire increased expression of cIAP-1, Bclx and p27(Kip1).

Chamulitrat W, Sattayakhom A, Herold-Mende C, Stremmel W.

Exp Dermatol. 2009 Dec;18(12):1067-9. doi: 10.1111/j.1600-0625.2009.00888.x. Erratum in: Exp Dermatol. 2010 Aug;19(8):772. Herold-Mended, Christel [corrected to Herold-Mende, Christel].

PMID:
19397698
36.

2,3-dehydrosilybin is a better DNA topoisomerase I inhibitor than its parental silybin.

Thongphasuk P, Stremmel W, Chamulitrat W.

Chemotherapy. 2009;55(1):42-8. doi: 10.1159/000175466. Epub 2008 Nov 21.

PMID:
19023201
37.

Triterpene saponins from Chenopodium quinoa Willd.

Kuljanabhagavad T, Thongphasuk P, Chamulitrat W, Wink M.

Phytochemistry. 2008 Jun;69(9):1919-26. doi: 10.1016/j.phytochem.2008.03.001. Epub 2008 Apr 29.

PMID:
18452959
38.

Significantly greater antioxidant anticancer activities of 2,3-dehydrosilybin than silybin.

Huber A, Thongphasuk P, Erben G, Lehmann WD, Tuma S, Stremmel W, Chamulitrat W.

Biochim Biophys Acta. 2008 May;1780(5):837-47. doi: 10.1016/j.bbagen.2007.12.012. Epub 2008 Jan 3.

PMID:
18222181
39.

Discrimination of epithelium-like and fibroblast-like phenotypes derived from ethanol-treated immortalised human gingival keratinocytes in epithelial equivalents.

Müssig E, Steinberg T, Kohl A, Chamulitrat W, Komposch G, Tomakidi P.

Cell Tissue Res. 2008 Apr;332(1):57-71. doi: 10.1007/s00441-007-0551-y. Epub 2008 Jan 10.

PMID:
18188601
40.

Potent direct or TNF-alpha-promoted anticancer effects of 2,3-dehydrosilybin: comparison study with silybin.

Thongphasuk P, Stremmel W, Chamulitrat W.

Chemotherapy. 2008;54(1):23-30. Epub 2007 Dec 7.

PMID:
18063863
41.

Nox1 induces differentiation resistance in immortalized human keratinocytes generating cells that express simple epithelial keratins.

Chamulitrat W, Huber A, Riedel HD, Stremmel W.

J Invest Dermatol. 2007 Sep;127(9):2171-83. Epub 2007 Apr 26.

42.

Human gingival mucosal keratinocytes exhibiting anchorage-independent growth express increased inducible nitric oxide synthase: regulation by MAP kinases.

Chunglok W, Ittarat W, Tomakidi P, Schmidt R, Stremmel W, Chamulitrat W.

Nitric Oxide. 2004 Nov;11(3):237-46.

PMID:
15566970
43.

A constitutive NADPH oxidase-like system containing gp91phox homologs in human keratinocytes.

Chamulitrat W, Stremmel W, Kawahara T, Rokutan K, Fujii H, Wingler K, Schmidt HH, Schmidt R.

J Invest Dermatol. 2004 Apr;122(4):1000-9.

44.

Association of gp91phox homolog Nox1 with anchorage-independent growth and MAP kinase-activation of transformed human keratinocytes.

Chamulitrat W, Schmidt R, Tomakidi P, Stremmel W, Chunglok W, Kawahara T, Rokutan K.

Oncogene. 2003 Sep 4;22(38):6045-53.

PMID:
12955083
45.

Epithelium and fibroblast-like phenotypes derived from HPV16 E6/E7-immortalized human gingival keratinocytes following chronic ethanol treatment.

Chamulitrat W, Schmidt R, Chunglok W, Kohl A, Tomakidi P.

Eur J Cell Biol. 2003 Jun;82(6):313-22.

PMID:
12868599
46.

A comparison of the NADPH oxidase in human sperm and white blood cells.

Armstrong JS, Bivalacqua TJ, Chamulitrat W, Sikka S, Hellstrom WJ.

Int J Androl. 2002 Aug;25(4):223-9.

PMID:
12121572
47.
48.

Desulfonation of a colitis inducer 2,4,6-trinitrobenzene sulfonic acid produces sulfite radical.

Chamulitrat W.

Biochim Biophys Acta. 1999 Oct 18;1472(1-2):368-75.

PMID:
10572958
50.

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