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Items: 1 to 50 of 75

1.

VISTA expressed in tumour cells regulates T cell function.

Mulati K, Hamanishi J, Matsumura N, Chamoto K, Mise N, Abiko K, Baba T, Yamaguchi K, Horikawa N, Murakami R, Taki M, Budiman K, Zeng X, Hosoe Y, Azuma M, Konishi I, Mandai M.

Br J Cancer. 2018 Nov 9. doi: 10.1038/s41416-018-0313-5. [Epub ahead of print]

PMID:
30382166
2.

PPAR-Induced Fatty Acid Oxidation in T Cells Increases the Number of Tumor-Reactive CD8+ T Cells and Facilitates Anti-PD-1 Therapy.

Chowdhury PS, Chamoto K, Kumar A, Honjo T.

Cancer Immunol Res. 2018 Nov;6(11):1375-1387. doi: 10.1158/2326-6066.CIR-18-0095. Epub 2018 Aug 24.

PMID:
30143538
3.

Combination therapy strategies for improving PD-1 blockade efficacy: a new era in cancer immunotherapy.

Chowdhury PS, Chamoto K, Honjo T.

J Intern Med. 2018 Feb;283(2):110-120. doi: 10.1111/joim.12708. Epub 2017 Nov 16. Review.

PMID:
29071761
4.

Metabolic shift induced by systemic activation of T cells in PD-1-deficient mice perturbs brain monoamines and emotional behavior.

Miyajima M, Zhang B, Sugiura Y, Sonomura K, Guerrini MM, Tsutsui Y, Maruya M, Vogelzang A, Chamoto K, Honda K, Hikida T, Ito S, Qin H, Sanuki R, Suzuki K, Furukawa T, Ishihama Y, Matsuda F, Suematsu M, Honjo T, Fagarasan S.

Nat Immunol. 2017 Dec;18(12):1342-1352. doi: 10.1038/ni.3867. Epub 2017 Oct 23.

PMID:
29058703
5.

Role of PD-1 in Immunity and Diseases.

Chamoto K, Al-Habsi M, Honjo T.

Curr Top Microbiol Immunol. 2017;410:75-97. doi: 10.1007/82_2017_67.

PMID:
28929192
6.

HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway.

Yamashita Y, Anczurowski M, Nakatsugawa M, Tanaka M, Kagoya Y, Sinha A, Chamoto K, Ochi T, Guo T, Saso K, Butler MO, Minden MD, Kislinger T, Hirano N.

Nat Commun. 2017 May 10;8:15244. doi: 10.1038/ncomms15244.

7.

Correction: Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs.

Chamoto K, Guo T, Scally SW, Kagoya Y, Anczurowski M, Wang CH, Rahman MA, Saso K, Butler MO, Chiu PPL, Julien JP, Hirano N.

J Immunol. 2017 May 1;198(9):3757. doi: 10.4049/jimmunol.1700296. No abstract available.

8.

Cancer immunotherapies targeting the PD-1 signaling pathway.

Iwai Y, Hamanishi J, Chamoto K, Honjo T.

J Biomed Sci. 2017 Apr 4;24(1):26. doi: 10.1186/s12929-017-0329-9. Review.

9.

Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity.

Chamoto K, Chowdhury PS, Kumar A, Sonomura K, Matsuda F, Fagarasan S, Honjo T.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E761-E770. doi: 10.1073/pnas.1620433114. Epub 2017 Jan 17.

10.

Erratum to: Role of PD-1 in Immunity and Diseases.

Chamoto K, Al-Habsi M, Honjo T.

Curr Top Microbiol Immunol. 2017;410:E1. doi: 10.1007/978-3-319-68929-6_69. No abstract available.

PMID:
29492725
11.

Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs.

Chamoto K, Guo T, Scally SW, Kagoya Y, Anczurowski M, Wang CH, Rahman MA, Saso K, Butler MO, Chiu PP, Julien JP, Hirano N.

J Immunol. 2017 Feb 1;198(3):1056-1065. doi: 10.4049/jimmunol.1601556. Epub 2016 Dec 21. Erratum in: J Immunol. 2017 May 1;198(9):3757.

12.

Immune checkpoint inhibitors targeting programmed cell death-1 (PD-1) in cancer therapy.

Hatae R, Chamoto K.

Rinsho Ketsueki. 2016;57(10):2224-2231. Japanese.

PMID:
27795534
13.

Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors.

Guo T, Chamoto K, Nakatsugawa M, Ochi T, Yamashita Y, Anczurowski M, Butler MO, Hirano N.

PLoS One. 2016 May 23;11(5):e0156114. doi: 10.1371/journal.pone.0156114. eCollection 2016.

14.

CD4(+) and CD8(+) TCRβ repertoires possess different potentials to generate extraordinarily high-avidity T cells.

Nakatsugawa M, Rahman MA, Yamashita Y, Ochi T, Wnuk P, Tanaka S, Chamoto K, Kagoya Y, Saso K, Guo T, Anczurowski M, Butler MO, Hirano N.

Sci Rep. 2016 Mar 31;6:23821. doi: 10.1038/srep23821.

15.

CDR3β sequence motifs regulate autoreactivity of human invariant NKT cell receptors.

Chamoto K, Guo T, Imataki O, Tanaka M, Nakatsugawa M, Ochi T, Yamashita Y, Saito AM, Saito TI, Butler MO, Hirano N.

J Autoimmun. 2016 Apr;68:39-51. doi: 10.1016/j.jaut.2015.12.005. Epub 2015 Dec 31.

16.

Adoptive T Cell Therapy Targeting CD1 and MR1.

Guo T, Chamoto K, Hirano N.

Front Immunol. 2015 May 20;6:247. doi: 10.3389/fimmu.2015.00247. eCollection 2015. Review.

17.

Optimization of T-cell Reactivity by Exploiting TCR Chain Centricity for the Purpose of Safe and Effective Antitumor TCR Gene Therapy.

Ochi T, Nakatsugawa M, Chamoto K, Tanaka S, Yamashita Y, Guo T, Fujiwara H, Yasukawa M, Butler MO, Hirano N.

Cancer Immunol Res. 2015 Sep;3(9):1070-81. doi: 10.1158/2326-6066.CIR-14-0222. Epub 2015 May 5.

18.

Specific roles of each TCR hemichain in generating functional chain-centric TCR.

Nakatsugawa M, Yamashita Y, Ochi T, Tanaka S, Chamoto K, Guo T, Butler MO, Hirano N.

J Immunol. 2015 Apr 1;194(7):3487-500. doi: 10.4049/jimmunol.1401717. Epub 2015 Feb 20.

19.

Alveolar epithelial dynamics in postpneumonectomy lung growth.

Chamoto K, Gibney BC, Ackermann M, Lee GS, Konerding MA, Tsuda A, Mentzer SJ.

Anat Rec (Hoboken). 2013 Mar;296(3):495-503. doi: 10.1002/ar.22659.

20.

Migration of CD11b+ accessory cells during murine lung regeneration.

Chamoto K, Gibney BC, Lee GS, Ackermann M, Konerding MA, Tsuda A, Mentzer SJ.

Stem Cell Res. 2013 May;10(3):267-77. doi: 10.1016/j.scr.2012.12.006. Epub 2013 Jan 5.

21.

Detection of murine post-pneumonectomy lung regeneration by 18FDG PET imaging.

Gibney BC, Park MA, Chamoto K, Ysasi A, Konerding MA, Tsuda A, Mentzer SJ.

EJNMMI Res. 2012 Sep 21;2(1):48. doi: 10.1186/2191-219X-2-48.

22.

Mechanostructural adaptations preceding postpneumonectomy lung growth.

Gibney BC, Houdek JP, Chamoto K, Lee GS, Ackermann M, Lin M, Collings-Simpson D, Konerding MA, Tsuda A, Mentzer SJ.

Exp Lung Res. 2012 Oct;38(8):396-405. doi: 10.3109/01902148.2012.715364. Epub 2012 Aug 20.

23.

Alveolar macrophage dynamics in murine lung regeneration.

Chamoto K, Gibney BC, Ackermann M, Lee GS, Lin M, Konerding MA, Tsuda A, Mentzer SJ.

J Cell Physiol. 2012 Sep;227(9):3208-15. doi: 10.1002/jcp.24009.

24.

Spatial dependence of alveolar angiogenesis in post-pneumonectomy lung growth.

Konerding MA, Gibney BC, Houdek JP, Chamoto K, Ackermann M, Lee GS, Lin M, Tsuda A, Mentzer SJ.

Angiogenesis. 2012 Mar;15(1):23-32. doi: 10.1007/s10456-011-9236-y. Epub 2011 Oct 4.

25.

CD34+ progenitor to endothelial cell transition in post-pneumonectomy angiogenesis.

Chamoto K, Gibney BC, Lee GS, Lin M, Collings-Simpson D, Voswinckel R, Konerding MA, Tsuda A, Mentzer SJ.

Am J Respir Cell Mol Biol. 2012 Mar;46(3):283-9. doi: 10.1165/rcmb.2011-0249OC. Epub 2011 Sep 15.

26.

Angiogenesis gene expression in murine endothelial cells during post-pneumonectomy lung growth.

Lin M, Chamoto K, Gibney BC, Lee GS, Collings-Simpson D, Houdek J, Konerding MA, Tsuda A, Mentzer SJ.

Respir Res. 2011 Jul 27;12:98. doi: 10.1186/1465-9921-12-98.

27.

Dynamic determination of oxygenation and lung compliance in murine pneumonectomy.

Gibney BC, Lee GS, Houdek JP, Lin M, Miele LF, Chamoto K, Konerding MA, Tsuda A, Mentzer SJ.

Exp Lung Res. 2011 Jun;37(5):301-9. doi: 10.3109/01902148.2011.561399. Epub 2011 May 16.

28.

Cross-circulation and cell distribution kinetics in parabiotic mice.

Gibney BC, Chamoto K, Lee GS, Simpson DC, Miele LF, Tsuda A, Konerding MA, Wagers A, Mentzer SJ.

J Cell Physiol. 2012 Feb;227(2):821-8. doi: 10.1002/jcp.22796.

29.

Blockade of IL-6-signaling inhibits the pathogenesis of CD4+ T cell-mediated lethal graft-versus-host reaction against minor histocompatibility antigen.

Noguchi D, Wakita D, Ohkuri T, Tajima M, Chamoto K, Kitamura H, Nishimura T.

Immunol Lett. 2011 May;136(2):146-55. doi: 10.1016/j.imlet.2011.01.004. Epub 2011 Jan 20.

PMID:
21256159
30.

Toll-like receptor-dependent IL-12 production by dendritic cells is required for activation of natural killer cell-mediated Type-1 immunity induced by Chrysanthemum coronarium L.

Tanaka S, Koizumi S, Masuko K, Makiuchi N, Aoyagi Y, Quivy E, Mitamura R, Kano T, Ohkuri T, Wakita D, Chamoto K, Kitamura H, Nishimura T.

Int Immunopharmacol. 2011 Feb;11(2):226-32. doi: 10.1016/j.intimp.2010.11.026. Epub 2010 Dec 7.

PMID:
21144920
31.

The extract of Japanese soybean, Kurosengoku activates the production of IL-12 and IFN-γ by DC or NK1.1(+) cells in a TLR4- and TLR2-dependent manner.

Tanaka S, Koizumi S, Makiuchi N, Aoyagi Y, Quivy E, Mitamura R, Kano T, Wakita D, Chamoto K, Kitamura H, Nishimura T.

Cell Immunol. 2011;266(2):135-42. doi: 10.1016/j.cellimm.2010.09.009. Epub 2010 Oct 1.

PMID:
20971456
32.

1α,25-Dihydroxyvitamin D3 and all-trans retinoic acid synergistically inhibit the differentiation and expansion of Th17 cells.

Ikeda U, Wakita D, Ohkuri T, Chamoto K, Kitamura H, Iwakura Y, Nishimura T.

Immunol Lett. 2010 Nov 30;134(1):7-16. doi: 10.1016/j.imlet.2010.07.002. Epub 2010 Jul 23.

PMID:
20655952
33.

A T(h)17-polarized cell population that has infiltrated the lung requires cells that convert to IFN-{gamma} production in order to induce airway hyperresponsiveness.

Ashino S, Wakita D, Shiohama Y, Iwakura Y, Chamoto K, Ohkuri T, Kitamura H, Nishimura T.

Int Immunol. 2010 Jun;22(6):503-13. doi: 10.1093/intimm/dxq034. Epub 2010 May 25.

PMID:
20501609
34.

Tumor-infiltrating IL-17-producing gammadelta T cells support the progression of tumor by promoting angiogenesis.

Wakita D, Sumida K, Iwakura Y, Nishikawa H, Ohkuri T, Chamoto K, Kitamura H, Nishimura T.

Eur J Immunol. 2010 Jul;40(7):1927-37. doi: 10.1002/eji.200940157.

35.

Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy.

Takeshima T, Chamoto K, Wakita D, Ohkuri T, Togashi Y, Shirato H, Kitamura H, Nishimura T.

Cancer Res. 2010 Apr 1;70(7):2697-706. doi: 10.1158/0008-5472.CAN-09-2982. Epub 2010 Mar 9.

36.

3-Methylcholanthrene-induced transforming growth factor-beta-producing carcinomas, but not sarcomas, are refractory to regulatory T cell-depletion therapy.

Chamoto K, Wakita D, Ohkuri T, Uchinami Y, Matsushima K, Kitamura H, Nishimura T.

Cancer Sci. 2010 Apr;101(4):855-61. doi: 10.1111/j.1349-7006.2009.01469.x. Epub 2009 Dec 11.

37.

Inhibition of phosphodiesterase 7A ameliorates Concanavalin A-induced hepatitis in mice.

Goto M, Tanaka Y, Murakawa M, Kadoshima-Yamaoka K, Inoue H, Murafuji H, Nagahira A, Kanki S, Hayashi Y, Nagahira K, Ogata A, Miura K, Nakatsuka T, Chamoto K, Fukuda Y, Nishimura T.

Int Immunopharmacol. 2009 Oct;9(11):1347-51. doi: 10.1016/j.intimp.2009.08.002. Epub 2009 Aug 8.

PMID:
19671449
38.

IFN-gamma-dependent type 1 immunity is crucial for immunosurveillance against squamous cell carcinoma in a novel mouse carcinogenesis model.

Wakita D, Chamoto K, Ohkuri T, Narita Y, Ashino S, Sumida K, Nishikawa H, Shiku H, Togashi Y, Kitamura H, Nishimura T.

Carcinogenesis. 2009 Aug;30(8):1408-15. doi: 10.1093/carcin/bgp144. Epub 2009 Jun 9.

PMID:
19509217
39.

Phosphodiesterase 7A inhibitor ASB16165 suppresses proliferation and cytokine production of NKT cells.

Goto M, Murakawa M, Kadoshima-Yamaoka K, Tanaka Y, Inoue H, Murafuji H, Hayashi Y, Miura K, Nakatsuka T, Nagahira K, Chamoto K, Fukuda Y, Nishimura T.

Cell Immunol. 2009;258(2):147-51. doi: 10.1016/j.cellimm.2009.04.005. Epub 2009 May 27.

PMID:
19477436
40.

Identification of novel helper epitopes of MAGE-A4 tumour antigen: useful tool for the propagation of Th1 cells.

Ohkuri T, Wakita D, Chamoto K, Togashi Y, Kitamura H, Nishimura T.

Br J Cancer. 2009 Apr 7;100(7):1135-43. doi: 10.1038/sj.bjc.6604966. Epub 2009 Mar 10.

41.
42.

Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells.

Chamoto K, Takeshima T, Wakita D, Ohkuri T, Ashino S, Omatsu T, Shirato H, Kitamura H, Togashi Y, Nishimura T.

Cancer Sci. 2009 May;100(5):934-9. doi: 10.1111/j.1349-7006.2009.01114.x. Epub 2009 Feb 24.

43.

ASB16165, a novel inhibitor for phosphodiesterase 7A (PDE7A), suppresses IL-12-induced IFN-gamma production by mouse activated T lymphocytes.

Kadoshima-Yamaoka K, Murakawa M, Goto M, Tanaka Y, Inoue H, Murafuji H, Nagahira A, Hayashi Y, Nagahira K, Miura K, Nakatsuka T, Chamoto K, Fukuda Y, Nishimura T.

Immunol Lett. 2009 Feb 21;122(2):193-7. doi: 10.1016/j.imlet.2009.01.004. Epub 2009 Feb 3.

PMID:
19195485
44.

Effect of phosphodiesterase 7 inhibitor ASB16165 on development and function of cytotoxic T lymphocyte.

Kadoshima-Yamaoka K, Murakawa M, Goto M, Tanaka Y, Inoue H, Murafuji H, Hayashi Y, Nagahira K, Miura K, Nakatsuka T, Chamoto K, Fukuda Y, Nishimura T.

Int Immunopharmacol. 2009 Jan;9(1):97-102. doi: 10.1016/j.intimp.2008.10.005. Epub 2008 Nov 6.

PMID:
18992850
45.

Essential role of Toll-like receptors for dendritic cell and NK1.1(+) cell-dependent activation of type 1 immunity by Lactobacillus pentosus strain S-PT84.

Koizumi S, Wakita D, Sato T, Mitamura R, Izumo T, Shibata H, Kiso Y, Chamoto K, Togashi Y, Kitamura H, Nishimura T.

Immunol Lett. 2008 Oct 30;120(1-2):14-9. doi: 10.1016/j.imlet.2008.06.003. Epub 2008 Jul 11. Erratum in: Immunol Lett.2008 Dec 22;121(2):173-4.

PMID:
18620001
46.

Sialyl lewisx antigen-expressing human CD4+ T and CD8+ T cells as initial immune responders in memory phenotype subsets.

Zhang Y, Ohkuri T, Wakita D, Narita Y, Chamoto K, Kitamura H, Nishimura T.

J Leukoc Biol. 2008 Sep;84(3):730-5. doi: 10.1189/jlb.0907599. Epub 2008 Jun 3.

PMID:
18523229
47.

IL-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8+ T cells.

Tajima M, Wakita D, Noguchi D, Chamoto K, Yue Z, Fugo K, Ishigame H, Iwakura Y, Kitamura H, Nishimura T.

J Exp Med. 2008 May 12;205(5):1019-27. doi: 10.1084/jem.20071133. Epub 2008 Apr 21.

48.

Anti-OX40 monoclonal antibody therapy in combination with radiotherapy results in therapeutic antitumor immunity to murine lung cancer.

Yokouchi H, Yamazaki K, Chamoto K, Kikuchi E, Shinagawa N, Oizumi S, Hommura F, Nishimura T, Nishimura M.

Cancer Sci. 2008 Feb;99(2):361-7. doi: 10.1111/j.1349-7006.2007.00664.x. Epub 2008 Jan 14.

49.

CpG-ODN inhibits airway inflammation at effector phase through down-regulation of antigen-specific Th2-cell migration into lung.

Ashino S, Wakita D, Zhang Y, Chamoto K, Kitamura H, Nishimura T.

Int Immunol. 2008 Feb;20(2):259-66. Epub 2007 Dec 21.

PMID:
18156622
50.

Blocking of IL-6 signaling pathway prevents CD4+ T cell-mediated colitis in a T(h)17-independent manner.

Noguchi D, Wakita D, Tajima M, Ashino S, Iwakura Y, Zhang Y, Chamoto K, Kitamura H, Nishimura T.

Int Immunol. 2007 Dec;19(12):1431-40. Epub 2007 Nov 1.

PMID:
17981790

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