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Items: 1 to 50 of 1017

1.

Synthesis and pH-responsive dissociation of framboidal ABC triblock copolymer vesicles in aqueous solution.

Mable CJ, Fielding LA, Derry MJ, Mykhaylyk OO, Chambon P, Armes SP.

Chem Sci. 2017 Dec 13;9(6):1454-1463. doi: 10.1039/c7sc04788f. eCollection 2018 Feb 14.

2.

γ-Secretase Inhibition Lowers Plasma Triglyceride-Rich Lipoproteins by Stabilizing the LDL Receptor.

Kim K, Goldberg IJ, Graham MJ, Sundaram M, Bertaggia E, Lee SX, Qiang L, Haeusler RA, Metzger D, Chambon P, Yao Z, Ginsberg HN, Pajvani UB.

Cell Metab. 2018 Apr 3;27(4):816-827.e4. doi: 10.1016/j.cmet.2018.02.010. Epub 2018 Mar 22.

PMID:
29576536
3.

RORα-expressing T regulatory cells restrain allergic skin inflammation.

Malhotra N, Leyva-Castillo JM, Jadhav U, Barreiro O, Kam C, O'Neill NK, Meylan F, Chambon P, von Andrian UH, Siegel RM, Wang EC, Shivdasani R, Geha RS.

Sci Immunol. 2018 Mar 2;3(21). pii: eaao6923. doi: 10.1126/sciimmunol.aao6923.

PMID:
29500225
4.

Metabolic causes of nonimmune hydrops fetalis: A next-generation sequencing panel as a first-line investigation.

Sudrié-Arnaud B, Marguet F, Patrier S, Martinovic J, Louillet F, Broux F, Charbonnier F, Dranguet H, Coutant S, Vezain M, Lanos R, Tebani A, Fuller M, Lamari F, Chambon P, Brehin AC, Trestard L, Tournier I, Marret S, Verspyck E, Laquerrière A, Bekri S.

Clin Chim Acta. 2018 Jun;481:1-8. doi: 10.1016/j.cca.2018.02.023. Epub 2018 Feb 22.

PMID:
29476731
5.

1st INEXO Symposium: Alternative models in vitro, ex ovo and organisms: From research to applications in pathologies and aging.

Nirdé P, Richaud M, Dabboue H, Reynier JP, Galas S, Vincent LA, Moles JP, Marti-Mestres G, Chambon P.

ALTEX. 2018;35(1):123-125. doi: 10.14573/altex.1711101. No abstract available.

6.

Roles of activating functions 1 and 2 of estrogen receptor α in lymphopoiesis.

Andersson A, Törnqvist AE, Moverare-Skrtic S, Bernardi AI, Farman HH, Chambon P, Engdahl C, Lagerquist MK, Windahl SH, Carlsten H, Ohlsson C, Islander U.

J Endocrinol. 2018 Feb;236(2):99-109. doi: 10.1530/JOE-17-0372. Epub 2017 Dec 18.

PMID:
29255084
7.

BRG1-SWI/SNF-dependent regulation of the Wt1 transcriptional landscape mediates epicardial activity during heart development and disease.

Vieira JM, Howard S, Villa Del Campo C, Bollini S, Dubé KN, Masters M, Barnette DN, Rohling M, Sun X, Hankins LE, Gavriouchkina D, Williams R, Metzger D, Chambon P, Sauka-Spengler T, Davies B, Riley PR.

Nat Commun. 2017 Jul 24;8:16034. doi: 10.1038/ncomms16034.

8.

YY1 Haploinsufficiency Causes an Intellectual Disability Syndrome Featuring Transcriptional and Chromatin Dysfunction.

Gabriele M, Vulto-van Silfhout AT, Germain PL, Vitriolo A, Kumar R, Douglas E, Haan E, Kosaki K, Takenouchi T, Rauch A, Steindl K, Frengen E, Misceo D, Pedurupillay CRJ, Stromme P, Rosenfeld JA, Shao Y, Craigen WJ, Schaaf CP, Rodriguez-Buritica D, Farach L, Friedman J, Thulin P, McLean SD, Nugent KM, Morton J, Nicholl J, Andrieux J, Stray-Pedersen A, Chambon P, Patrier S, Lynch SA, Kjaergaard S, Tørring PM, Brasch-Andersen C, Ronan A, van Haeringen A, Anderson PJ, Powis Z, Brunner HG, Pfundt R, Schuurs-Hoeijmakers JHM, van Bon BWM, Lelieveld S, Gilissen C, Nillesen WM, Vissers LELM, Gecz J, Koolen DA, Testa G, de Vries BBA.

Am J Hum Genet. 2017 Jun 1;100(6):907-925. doi: 10.1016/j.ajhg.2017.05.006.

9.

Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications.

Arnal JF, Lenfant F, Metivier R, Flouriot G, Henrion D, Adlanmerini M, Fontaine C, Gourdy P, Chambon P, Katzenellenbogen B, Katzenellenbogen J.

Physiol Rev. 2017 Jul 1;97(3):1045-1087. doi: 10.1152/physrev.00024.2016. Review.

10.

Autologous Myoblasts for the Treatment of Fecal Incontinence: Results of a Phase 2 Randomized Placebo-controlled Study (MIAS).

Boyer O, Bridoux V, Giverne C, Bisson A, Koning E, Leroi AM, Chambon P, Déhayes J, Le Corre S, Jacquot S, Bastit D, Martinet J, Houivet E, Tuech JJ, Benichou J, Michot F; and the Study Group of Myoblast Therapy for Faecal Incontinence.

Ann Surg. 2018 Mar;267(3):443-450. doi: 10.1097/SLA.0000000000002268.

11.

Similarities and differences in the transcriptional control of expression of the mouse TSLP gene in skin epidermis and intestinal epithelium.

Ganti KP, Mukherji A, Surjit M, Li M, Chambon P.

Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E951-E960. doi: 10.1073/pnas.1620697114. Epub 2017 Jan 23.

12.

Regeneration of fat cells from myofibroblasts during wound healing.

Plikus MV, Guerrero-Juarez CF, Ito M, Li YR, Dedhia PH, Zheng Y, Shao M, Gay DL, Ramos R, Hsi TC, Oh JW, Wang X, Ramirez A, Konopelski SE, Elzein A, Wang A, Supapannachart RJ, Lee HL, Lim CH, Nace A, Guo A, Treffeisen E, Andl T, Ramirez RN, Murad R, Offermanns S, Metzger D, Chambon P, Widgerow AD, Tuan TL, Mortazavi A, Gupta RK, Hamilton BA, Millar SE, Seale P, Pear WS, Lazar MA, Cotsarelis G.

Science. 2017 Feb 17;355(6326):748-752. doi: 10.1126/science.aai8792. Epub 2017 Jan 5.

13.

Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis.

Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, Reber LL, Pirottin D, Kim J, Chambon P, Roers A, Antoine N, Kawakami Y, Kawakami T, Bureau F, Tam SY, Tsai M, Galli SJ.

J Clin Invest. 2016 Dec 1;126(12):4497-4515. doi: 10.1172/JCI86359. Epub 2016 Nov 7.

14.

Xq28 duplication including MECP2 in six unreported affected females: what can we learn for diagnosis and genetic counselling?

El Chehadeh S, Touraine R, Prieur F, Reardon W, Bienvenu T, Chantot-Bastaraud S, Doco-Fenzy M, Landais E, Philippe C, Marle N, Callier P, Mosca-Boidron AL, Mugneret F, Le Meur N, Goldenberg A, Guerrot AM, Chambon P, Satre V, Coutton C, Jouk PS, Devillard F, Dieterich K, Afenjar A, Burglen L, Moutard ML, Addor MC, Lebon S, Martinet D, Alessandri JL, Doray B, Miguet M, Devys D, Saugier-Veber P, Drunat S, Aral B, Kremer V, Rondeau S, Tabet AC, Thevenon J, Thauvin-Robinet C, Perreton N, Des Portes V, Faivre L.

Clin Genet. 2017 Apr;91(4):576-588. doi: 10.1111/cge.12898. Epub 2017 Feb 16.

PMID:
27761913
15.

Insulin receptor isoform A ameliorates long-term glucose intolerance in diabetic mice.

Diaz-Castroverde S, Gómez-Hernández A, Fernández S, García-Gómez G, Di Scala M, González-Aseguinolaza G, Fernández-Millán E, González-Rodríguez Á, García-Bravo M, Chambon P, Álvarez C, Perdomo L, Beneit N, Escribano O, Benito M.

Dis Model Mech. 2016 Nov 1;9(11):1271-1281. Epub 2016 Aug 24.

16.

Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis.

Xie T, Liang J, Liu N, Huan C, Zhang Y, Liu W, Kumar M, Xiao R, D'Armiento J, Metzger D, Chambon P, Papaioannou VE, Stripp BR, Jiang D, Noble PW.

J Clin Invest. 2016 Sep 1;126(9):3626. doi: 10.1172/JCI89968. Epub 2016 Aug 22. No abstract available.

17.

Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis.

Xie T, Liang J, Liu N, Huan C, Zhang Y, Liu W, Kumar M, Xiao R, D'Armiento J, Metzger D, Chambon P, Papaioannou VE, Stripp BR, Jiang D, Noble PW.

J Clin Invest. 2016 Aug 1;126(8):3063-79. doi: 10.1172/JCI85328. Epub 2016 Jul 11.

18.

SERMs have substance-specific effects on bone, and these effects are mediated via ERαAF-1 in female mice.

Börjesson AE, Farman HH, Movérare-Skrtic S, Engdahl C, Antal MC, Koskela A, Tuukkanen J, Carlsten H, Krust A, Chambon P, Sjögren K, Lagerquist MK, Windahl SH, Ohlsson C.

Am J Physiol Endocrinol Metab. 2016 Jun 1;310(11):E912-8. doi: 10.1152/ajpendo.00488.2015. Epub 2016 Apr 5.

19.

Pregnancy outcomes in prenatally diagnosed 47, XXX and 47, XYY syndromes: a 30-year French, retrospective, multicentre study.

Gruchy N, Blondeel E, Le Meur N, Joly-Hélas G, Chambon P, Till M, Herbaux M, Vigouroux-Castera A, Coussement A, Lespinasse J, Amblard F, Jimenez Pocquet M, Lebel-Roy C, Carré-Pigeon F, Flori E, Mugneret F, Jaillard S, Yardin C, Harbuz R, Collonge-Rame MA, Vago P, Valduga M, Leporrier N, Vialard F.

Prenat Diagn. 2016 Jun;36(6):523-9. doi: 10.1002/pd.4817. Epub 2016 May 10.

PMID:
27018091
20.

Stable, polymer-directed and SPION-nucleated magnetic amphiphilic block copolymer nanoprecipitates with readily reversible assembly in magnetic fields.

Giardiello M, Hatton FL, Slater RA, Chambon P, North J, Peacock AK, He T, McDonald TO, Owen A, Rannard SP.

Nanoscale. 2016 Apr 7;8(13):7224-31. doi: 10.1039/c6nr00788k.

PMID:
26973155
21.

Role of highly branched, high molecular weight polymer structures in directing uniform polymer particle formation during nanoprecipitation.

Hatton FL, Chambon P, Savage AC, Rannard SP.

Chem Commun (Camb). 2016 Mar 11;52(20):3915-8. doi: 10.1039/c6cc00611f. Epub 2016 Feb 12.

PMID:
26871974
22.

Glucocorticoid-induced tethered transrepression requires SUMOylation of GR and formation of a SUMO-SMRT/NCoR1-HDAC3 repressing complex.

Hua G, Ganti KP, Chambon P.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E635-43. doi: 10.1073/pnas.1522826113. Epub 2015 Dec 28.

23.

GR SUMOylation and formation of an SUMO-SMRT/NCoR1-HDAC3 repressing complex is mandatory for GC-induced IR nGRE-mediated transrepression.

Hua G, Paulen L, Chambon P.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E626-34. doi: 10.1073/pnas.1522821113. Epub 2015 Dec 28.

24.

Shifting eating to the circadian rest phase misaligns the peripheral clocks with the master SCN clock and leads to a metabolic syndrome.

Mukherji A, Kobiita A, Damara M, Misra N, Meziane H, Champy MF, Chambon P.

Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):E6691-8. doi: 10.1073/pnas.1519807112. Epub 2015 Nov 16.

25.

Shifting the feeding of mice to the rest phase creates metabolic alterations, which, on their own, shift the peripheral circadian clocks by 12 hours.

Mukherji A, Kobiita A, Chambon P.

Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):E6683-90. doi: 10.1073/pnas.1519735112. Epub 2015 Nov 16.

26.

A de novo microdeletion of SEMA5A in a boy with autism spectrum disorder and intellectual disability.

Mosca-Boidron AL, Gueneau L, Huguet G, Goldenberg A, Henry C, Gigot N, Pallesi-Pocachard E, Falace A, Duplomb L, Thevenon J, Duffourd Y, St-Onge J, Chambon P, Rivière JB, Thauvin-Robinet C, Callier P, Marle N, Payet M, Ragon C, Goubran Botros H, Buratti J, Calderari S, Dumas G, Delorme R, Lagarde N, Pinoit JM, Rosier A, Masurel-Paulet A, Cardoso C, Mugneret F, Saugier-Veber P, Campion D, Faivre L, Bourgeron T.

Eur J Hum Genet. 2016 Jun;24(6):838-43. doi: 10.1038/ejhg.2015.211. Epub 2015 Sep 23.

27.

Protective Hematopoietic Effect of Estrogens in a Mouse Model of Thrombosis: Respective Roles of Nuclear Versus Membrane Estrogen Receptor α.

Valéra MC, Fontaine C, Lenfant F, Cabou C, Guillaume M, Smirnova N, Kim SH, Chambon P, Katzenellenbogen JA, Katzenellenbogen BS, Payrastre B, Arnal JF.

Endocrinology. 2015 Nov;156(11):4293-301. doi: 10.1210/en.2015-1522. Epub 2015 Aug 17.

28.

Synthesis, nanoprecipitation and pH sensitivity of amphiphilic linear-dendritic hybrid polymers and hyperbranched-polydendrons containing tertiary amine functional dendrons.

Rogers HE, Chambon P, Auty SE, Hern FY, Owen A, Rannard SP.

Soft Matter. 2015 Sep 21;11(35):7005-15. doi: 10.1039/c5sm00673b. Epub 2015 Aug 4.

PMID:
26241924
29.

Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition.

Gao L, Rabbitt EH, Condon JC, Renthal NE, Johnston JM, Mitsche MA, Chambon P, Xu J, O'Malley BW, Mendelson CR.

J Clin Invest. 2015 Jul 1;125(7):2808-24. doi: 10.1172/JCI78544. Epub 2015 Jun 22.

30.

Neonatal Estrogen Receptor β Is Important in the Permanent Inhibition of Epithelial Cell Proliferation in the Mouse Uterus.

Nakajima T, Tanimoto Y, Tanaka M, Chambon P, Watanabe H, Iguchi T, Sato T.

Endocrinology. 2015 Sep;156(9):3317-28. doi: 10.1210/en.2015-1012. Epub 2015 May 28.

PMID:
26020796
31.

Chromosomal instability but lack of transformation in human myoblast preparations.

Bisson A, Le Corre S, Joly-Helas G, Chambon P, Demoulins L, Jean L, Adriouch S, Drouot L, Giverne C, Roussel F, Jacquot S, Doucet C, Michot F, Lamacz M, Frébourg T, Flaman JM, Boyer O.

Cell Transplant. 2014;23(12):1475-87. doi: 10.3727/096368913X670192.

PMID:
25565635
32.

Hyperbranched polydendrons: a new nanomaterials platform with tuneable permeation through model gut epithelium.

Hatton FL, Tatham LM, Tidbury LR, Chambon P, He T, Owen A, Rannard SP.

Chem Sci. 2015 Jan 1;6(1):326-334. doi: 10.1039/c4sc02889a. Epub 2014 Oct 3.

33.

Estrogen receptor KO mice study on rapid modulation of spines and long-term depression in the hippocampus.

Murakami G, Hojo Y, Ogiue-Ikeda M, Mukai H, Chambon P, Nakajima K, Ooishi Y, Kimoto T, Kawato S.

Brain Res. 2015 Sep 24;1621:133-46. doi: 10.1016/j.brainres.2014.12.002. Epub 2014 Dec 9.

PMID:
25498865
34.

Disruption of TGF-β signaling in smooth muscle cell prevents flow-induced vascular remodeling.

Gao F, Chambon P, Tellides G, Kong W, Zhang X, Li W.

Biochem Biophys Res Commun. 2014 Nov 7;454(1):245-50. doi: 10.1016/j.bbrc.2014.10.092. Epub 2014 Oct 24.

PMID:
25451249
35.

Disruption of TGF-β signaling in smooth muscle cell prevents elastase-induced abdominal aortic aneurysm.

Gao F, Chambon P, Offermanns S, Tellides G, Kong W, Zhang X, Li W.

Biochem Biophys Res Commun. 2014 Nov 7;454(1):137-43. doi: 10.1016/j.bbrc.2014.10.053. Epub 2014 Oct 18. Erratum in: Biochem Biophys Res Commun. 2015 May 8;460(3):887.

PMID:
25450370
36.

Luminal cells are favored as the cell of origin for prostate cancer.

Wang ZA, Toivanen R, Bergren SK, Chambon P, Shen MM.

Cell Rep. 2014 Sep 11;8(5):1339-46. doi: 10.1016/j.celrep.2014.08.002. Epub 2014 Aug 28.

37.

The role of total and cartilage-specific estrogen receptor alpha expression for the ameliorating effect of estrogen treatment on arthritis.

Engdahl C, Börjesson AE, Forsman HF, Andersson A, Stubelius A, Krust A, Chambon P, Islander U, Ohlsson C, Carlsten H, Lagerquist MK.

Arthritis Res Ther. 2014 Jul 15;16(4):R150. doi: 10.1186/ar4612.

38.

History of retinoic acid receptors.

Benbrook DM, Chambon P, Rochette-Egly C, Asson-Batres MA.

Subcell Biochem. 2014;70:1-20. doi: 10.1007/978-94-017-9050-5_1. Review.

PMID:
24962878
39.

Pregnancy outcomes of prenatally diagnosed Turner syndrome: a French multicenter retrospective study including a series of 975 cases.

Gruchy N, Vialard F, Blondeel E, Le Meur N, Joly-Hélas G, Chambon P, Till M, Herbaut-Graux M, Vigouroux-Castera A, Coussement A, Lespinasse J, Amblard F, Jimenez M, Lebel Roy Camille L, Carré-Pigeon F, Flori E, Mugneret F, Jaillard S, Yardin C, Harbuz R, Collonge Rame M, Vago P, Valduga M, Leporrier N.

Prenat Diagn. 2014 Dec;34(12):1133-8. doi: 10.1002/pd.4439. Epub 2014 Jul 22.

PMID:
24961405
40.

[Malignant meningioma with adenocarcinoma-like metaplasia: a rare entity to be not misdiagnosed].

Marguet F, Proust F, Crahes M, Basset C, Joly-Helas G, Chambon P, Laquerrière A.

Ann Pathol. 2014 Jun;34(3):223-7. doi: 10.1016/j.annpat.2014.03.004. Epub 2014 May 17. French.

PMID:
24950872
41.

Estrogen receptor-alpha promotes alternative macrophage activation during cutaneous repair.

Campbell L, Emmerson E, Williams H, Saville CR, Krust A, Chambon P, Mace KA, Hardman MJ.

J Invest Dermatol. 2014 Sep;134(9):2447-2457. doi: 10.1038/jid.2014.175. Epub 2014 Apr 9.

42.

Effects of neuron-specific estrogen receptor (ER) α and ERβ deletion on the acute estrogen negative feedback mechanism in adult female mice.

Cheong RY, Porteous R, Chambon P, Abrahám I, Herbison AE.

Endocrinology. 2014 Apr;155(4):1418-27. doi: 10.1210/en.2013-1943. Epub 2014 Jan 29.

PMID:
24476134
43.

Absence of intestinal PPARγ aggravates acute infectious colitis in mice through a lipocalin-2-dependent pathway.

Kundu P, Ling TW, Korecka A, Li Y, D'Arienzo R, Bunte RM, Berger T, Arulampalam V, Chambon P, Mak TW, Wahli W, Pettersson S.

PLoS Pathog. 2014 Jan;10(1):e1003887. doi: 10.1371/journal.ppat.1003887. Epub 2014 Jan 23.

44.

Clinical assessment of five patients with BRWD3 mutation at Xq21.1 gives further evidence for mild to moderate intellectual disability and macrocephaly.

Grotto S, Drouin-Garraud V, Ounap K, Puusepp-Benazzouz H, Schuurs-Hoeijmakers J, Le Meur N, Chambon P, Fehrenbach S, van Bokhoven H, Frébourg T, de Brouwer AP, Saugier-Veber P.

Eur J Med Genet. 2014 Apr;57(5):200-6. doi: 10.1016/j.ejmg.2013.12.012. Epub 2014 Jan 22.

PMID:
24462886
45.

Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions.

Adlanmerini M, Solinhac R, Abot A, Fabre A, Raymond-Letron I, Guihot AL, Boudou F, Sautier L, Vessières E, Kim SH, Lière P, Fontaine C, Krust A, Chambon P, Katzenellenbogen JA, Gourdy P, Shaul PW, Henrion D, Arnal JF, Lenfant F.

Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):E283-90. doi: 10.1073/pnas.1322057111. Epub 2013 Dec 26.

46.

p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells.

Mardaryev AN, Gdula MR, Yarker JL, Emelianov VU, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Joffe B, Solovei I, Chambon P, Botchkarev VA, Fessing MY.

Development. 2014 Jan;141(1):101-11. doi: 10.1242/dev.103200. Erratum in: Development. 2014 Sep;141(17):3437. Joffe, Boris [added]; Solovei, Irina [added]; Emelianov, Vladimir N [corrected to Emelianov, Vladimir U].

47.

Prokineticin receptor 1 as a novel suppressor of preadipocyte proliferation and differentiation to control obesity.

Szatkowski C, Vallet J, Dormishian M, Messaddeq N, Valet P, Boulberdaa M, Metzger D, Chambon P, Nebigil CG.

PLoS One. 2013 Dec 4;8(12):e81175. doi: 10.1371/journal.pone.0081175. eCollection 2013.

49.

HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis.

Miyauchi Y, Sato Y, Kobayashi T, Yoshida S, Mori T, Kanagawa H, Katsuyama E, Fujie A, Hao W, Miyamoto K, Tando T, Morioka H, Matsumoto M, Chambon P, Johnson RS, Kato S, Toyama Y, Miyamoto T.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16568-73. doi: 10.1073/pnas.1308755110. Epub 2013 Sep 10.

50.

Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner.

Holik AZ, Krzystyniak J, Young M, Richardson K, Jardé T, Chambon P, Shorning BY, Clarke AR.

Stem Cells. 2013 Nov;31(11):2457-66. doi: 10.1002/stem.1498.

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