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Routine cervical screening by primary HPV testing: early findings in the renewed National Cervical Screening Program.

Machalek DA, Roberts JM, Garland SM, Thurloe J, Richards A, Chambers I, Sivertsen T, Farnsworth A.

Med J Aust. 2019 Jun 5. doi: 10.5694/mja2.50223. [Epub ahead of print]


OTX2 restricts entry to the mouse germline.

Zhang J, Zhang M, Acampora D, Vojtek M, Yuan D, Simeone A, Chambers I.

Nature. 2018 Oct;562(7728):595-599. doi: 10.1038/s41586-018-0581-5. Epub 2018 Oct 3.


Esrrb extinction triggers dismantling of naïve pluripotency and marks commitment to differentiation.

Festuccia N, Halbritter F, Corsinotti A, Gagliardi A, Colby D, Tomlinson SR, Chambers I.

EMBO J. 2018 Nov 2;37(21). pii: e95476. doi: 10.15252/embj.201695476. Epub 2018 Oct 1.


Hrg1 promotes heme-iron recycling during hemolysis in the zebrafish kidney.

Zhang J, Chambers I, Yun S, Phillips J, Krause M, Hamza I.

PLoS Genet. 2018 Sep 24;14(9):e1007665. doi: 10.1371/journal.pgen.1007665. eCollection 2018 Sep.


Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells.

Barakat TS, Halbritter F, Zhang M, Rendeiro AF, Perenthaler E, Bock C, Chambers I.

Cell Stem Cell. 2018 Aug 2;23(2):276-288.e8. doi: 10.1016/j.stem.2018.06.014. Epub 2018 Jul 19.


Forewarning of hypotensive events using a Bayesian artificial neural network in neurocritical care.

Donald R, Howells T, Piper I, Enblad P, Nilsson P, Chambers I, Gregson B, Citerio G, Kiening K, Neumann J, Ragauskas A, Sahuquillo J, Sinnott R, Stell A; BrainIT Group.

J Clin Monit Comput. 2019 Feb;33(1):39-51. doi: 10.1007/s10877-018-0139-y. Epub 2018 May 24.


Visualizing Cerebrovascular Autoregulation Insults and Their Association with Outcome in Adult and Paediatric Traumatic Brain Injury.

Flechet M, Meyfroidt G, Piper I, Citerio G, Chambers I, Jones PA, Lo TM, Enblad P, Nilsson P, Feyen B, Jorens P, Maas A, Schuhmann MU, Donald R, Moss L, Van den Berghe G, Depreitere B, Güiza F.

Acta Neurochir Suppl. 2018;126:291-295. doi: 10.1007/978-3-319-65798-1_57.


Cerebral Perfusion Pressure Variability Between Patients and Between Centres.

Depreitere B, Güiza F, Piper I, Citerio G, Chambers I, Jones PA, Lo TM, Enblad P, Nilsson P, Feyen B, Jorens P, Maas A, Schuhmann MU, Donald R, Moss L, Van den Berghe G, Meyfroidt G.

Acta Neurochir Suppl. 2018;126:3-6. doi: 10.1007/978-3-319-65798-1_1.


Dynamic changes in Sox2 spatio-temporal expression promote the second cell fate decision through Fgf4/Fgfr2 signaling in preimplantation mouse embryos.

Mistri TK, Arindrarto W, Ng WP, Wang C, Lim LH, Sun L, Chambers I, Wohland T, Robson P.

Biochem J. 2018 Mar 20;475(6):1075-1089. doi: 10.1042/BCJ20170418.


Esrrb Complementation Rescues Development of Nanog-Null Germ Cells.

Zhang M, Leitch HG, Tang WWC, Festuccia N, Hall-Ponsele E, Nichols J, Surani MA, Smith A, Chambers I.

Cell Rep. 2018 Jan 9;22(2):332-339. doi: 10.1016/j.celrep.2017.12.060.


Distinct SoxB1 networks are required for naïve and primed pluripotency.

Corsinotti A, Wong FC, Tatar T, Szczerbinska I, Halbritter F, Colby D, Gogolok S, Pantier R, Liggat K, Mirfazeli ES, Hall-Ponsele E, Mullin NP, Wilson V, Chambers I.

Elife. 2017 Dec 19;6. pii: e27746. doi: 10.7554/eLife.27746.


Functional Antagonism between OTX2 and NANOG Specifies a Spectrum of Heterogeneous Identities in Embryonic Stem Cells.

Acampora D, Di Giovannantonio LG, Garofalo A, Nigro V, Omodei D, Lombardi A, Zhang J, Chambers I, Simeone A.

Stem Cell Reports. 2017 Nov 14;9(5):1642-1659. doi: 10.1016/j.stemcr.2017.09.019. Epub 2017 Oct 19.


A new twist to Sin3 complexes in pluripotent cells.

Pantier R, Mullin NP, Chambers I.

EMBO J. 2017 Aug 1;36(15):2184-2186. doi: 10.15252/embj.201797516. Epub 2017 Jun 28. No abstract available.


Malignant Clear Cell Hidradenoma of the Breast.

Chambers I, Rahal AK, Reddy PS, Kallail KJ.

Cureus. 2017 Mar 1;9(3):e1064. doi: 10.7759/cureus.1064.


Cerebral Perfusion Pressure Insults and Associations with Outcome in Adult Traumatic Brain Injury.

Güiza F, Meyfroidt G, Piper I, Citerio G, Chambers I, Enblad P, Nillson P, Feyen B, Jorens P, Maas A, Schuhmann MU, Donald R, Moss L, Van den Berghe G, Depreitere B.

J Neurotrauma. 2017 Aug 15;34(16):2425-2431. doi: 10.1089/neu.2016.4807. Epub 2017 Jun 9.


Distinct Contributions of Tryptophan Residues within the Dimerization Domain to Nanog Function.

Mullin NP, Gagliardi A, Khoa LTP, Colby D, Hall-Ponsele E, Rowe AJ, Chambers I.

J Mol Biol. 2017 May 19;429(10):1544-1553. doi: 10.1016/j.jmb.2016.12.001. Epub 2016 Dec 6.


Differences in subsidence rate between alternative designs of a commonly used uncemented femoral stem.

Al-Najjim M, Khattak U, Sim J, Chambers I.

J Orthop. 2016 Jul 5;13(4):322-6. doi: 10.1016/j.jor.2016.06.026. eCollection 2016 Dec.


Extensive Bone Marrow Necrosis and Osteolytic Lesions in a Case of Acute Myeloid Leukemia Transformed from Polycythemia Vera.

Chambers I, Truong P, Kallail KJ, Palko W.

Cureus. 2016 Jun 13;8(6):e639. doi: 10.7759/cureus.639.


Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs.

Illich DJ, Zhang M, Ursu A, Osorno R, Kim KP, Yoon J, Araúzo-Bravo MJ, Wu G, Esch D, Sabour D, Colby D, Grassme KS, Chen J, Greber B, Höing S, Herzog W, Ziegler S, Chambers I, Gao S, Waldmann H, Schöler HR.

Cell Rep. 2016 Apr 26;15(4):787-800. doi: 10.1016/j.celrep.2016.03.073. Epub 2016 Apr 14.


The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells.

Novo CL, Tang C, Ahmed K, Djuric U, Fussner E, Mullin NP, Morgan NP, Hayre J, Sienerth AR, Elderkin S, Nishinakamura R, Chambers I, Ellis J, Bazett-Jones DP, Rugg-Gunn PJ.

Genes Dev. 2016 May 1;30(9):1101-15. doi: 10.1101/gad.275685.115. Epub 2016 Apr 28.


In-house development of a dedicated data acquisition and monitoring system for intracranial pressure, patient posture and patient symptoms in a regional neurosciences centre.

Marsden SP, Boddy IJ, Strachan RD, Chambers IR.

Physiol Meas. 2016 Feb;37(2):N1-10. doi: 10.1088/0967-3334/37/2/N1. Epub 2016 Jan 15.


Surgical Trial In Traumatic intraCerebral Haemorrhage (STITCH): a randomised controlled trial of Early Surgery compared with Initial Conservative Treatment.

Gregson BA, Rowan EN, Francis R, McNamee P, Boyers D, Mitchell P, McColl E, Chambers IR, Unterberg A, Mendelow AD; STITCH(TRAUMA) investigators.

Health Technol Assess. 2015 Sep;19(70):1-138. doi: 10.3310/hta19700.


Reprogramming Roadblocks Are System Dependent.

Chantzoura E, Skylaki S, Menendez S, Kim SI, Johnsson A, Linnarsson S, Woltjen K, Chambers I, Kaji K.

Stem Cell Reports. 2015 Sep 8;5(3):350-64. doi: 10.1016/j.stemcr.2015.07.007. Epub 2015 Aug 13.


Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells.

Mistri TK, Devasia AG, Chu LT, Ng WP, Halbritter F, Colby D, Martynoga B, Tomlinson SR, Chambers I, Robson P, Wohland T.

EMBO Rep. 2015 Sep;16(9):1177-91. doi: 10.15252/embr.201540467. Epub 2015 Aug 11.


Clinical pathologic conference case 4: just an extravasation mucocele?

Aldred MJ, Talacko AA, Hall GM, Chambers IG.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 May;119(5):e284-7. No abstract available.


Visualizing the pressure and time burden of intracranial hypertension in adult and paediatric traumatic brain injury.

Güiza F, Depreitere B, Piper I, Citerio G, Chambers I, Jones PA, Lo TY, Enblad P, Nillson P, Feyen B, Jorens P, Maas A, Schuhmann MU, Donald R, Moss L, Van den Berghe G, Meyfroidt G.

Intensive Care Med. 2015 Jun;41(6):1067-76. doi: 10.1007/s00134-015-3806-1. Epub 2015 Apr 18.


Early Surgery versus Initial Conservative Treatment in Patients with Traumatic Intracerebral Hemorrhage (STITCH[Trauma]): The First Randomized Trial.

Mendelow AD, Gregson BA, Rowan EN, Francis R, McColl E, McNamee P, Chambers IR, Unterberg A, Boyers D, Mitchell PM; STITCH(Trauma) Investigators.

J Neurotrauma. 2015 Sep 1;32(17):1312-23. doi: 10.1089/neu.2014.3644. Epub 2015 May 21.


A signal-to-cutoff ratio in the Abbott architect HIV Ag/Ab Combo assay that predicts subsequent confirmation of HIV-1 infection in a low-prevalence setting.

Jensen TO, Robertson P, Whybin R, Chambers I, Lahra M, Rawlinson W, Post JJ.

J Clin Microbiol. 2015 May;53(5):1709-11. doi: 10.1128/JCM.03583-14. Epub 2015 Feb 11.


The TONK score: a tool for assessing quality in trauma and orthopaedic note-keeping.

Khan Z, Sayers AE, Khattak MU, Chambers IR.

SICOT J. 2015 Nov 2;1:29. doi: 10.1051/sicotj/2015029.


Lessons in learning: An effective process for engaging 12- to 14-year-olds in stem cell biology.

Kemp E, Chambers I.

EMBO Rep. 2015 Jan;16(1):7-13. doi: 10.15252/embr.201439398. Epub 2014 Dec 17. No abstract available.


Update on patterns of mandibular fracture in Tasmania, Australia.

Verma S, Chambers I.

Br J Oral Maxillofac Surg. 2015 Jan;53(1):74-7. doi: 10.1016/j.bjoms.2014.10.003. Epub 2014 Nov 1.


Dental emergencies presenting to a general hospital emergency department in Hobart, Australia.

Verma S, Chambers I.

Aust Dent J. 2014 Sep;59(3):329-33. doi: 10.1111/adj.12202. Epub 2014 Jul 22.


Environmental gestagens activate fathead minnow (Pimephales promelas) nuclear progesterone and androgen receptors in vitro.

Ellestad LE, Cardon M, Chambers IG, Farmer JL, Hartig P, Stevens K, Villeneuve DL, Wilson V, Orlando EF.

Environ Sci Technol. 2014 Jul 15;48(14):8179-87. doi: 10.1021/es501428u. Epub 2014 Jun 24.


Transcription factor heterogeneity in pluripotent stem cells: a stochastic advantage.

Torres-Padilla ME, Chambers I.

Development. 2014 Jun;141(11):2173-81. doi: 10.1242/dev.102624. Review.


The role of pluripotency gene regulatory network components in mediating transitions between pluripotent cell states.

Festuccia N, Osorno R, Wilson V, Chambers I.

Curr Opin Genet Dev. 2013 Oct;23(5):504-11. doi: 10.1016/j.gde.2013.06.003. Epub 2013 Aug 7. Review.


A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

Gagliardi A, Mullin NP, Ying Tan Z, Colby D, Kousa AI, Halbritter F, Weiss JT, Felker A, Bezstarosti K, Favaro R, Demmers J, Nicolis SK, Tomlinson SR, Poot RA, Chambers I.

EMBO J. 2013 Aug 14;32(16):2231-47. doi: 10.1038/emboj.2013.161. Epub 2013 Jul 26.


The pluripotent genome in three dimensions is shaped around pluripotency factors.

de Wit E, Bouwman BA, Zhu Y, Klous P, Splinter E, Verstegen MJ, Krijger PH, Festuccia N, Nora EP, Welling M, Heard E, Geijsen N, Poot RA, Chambers I, de Laat W.

Nature. 2013 Sep 12;501(7466):227-31. doi: 10.1038/nature12420. Epub 2013 Jul 24.


Hes1 desynchronizes differentiation of pluripotent cells by modulating STAT3 activity.

Zhou X, Smith AJ, Waterhouse A, Blin G, Malaguti M, Lin CY, Osorno R, Chambers I, Lowell S.

Stem Cells. 2013 Aug;31(8):1511-22. doi: 10.1002/stem.1426.


Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog.

Karwacki-Neisius V, Göke J, Osorno R, Halbritter F, Ng JH, Weiße AY, Wong FC, Gagliardi A, Mullin NP, Festuccia N, Colby D, Tomlinson SR, Ng HH, Chambers I.

Cell Stem Cell. 2013 May 2;12(5):531-45. doi: 10.1016/j.stem.2013.04.023.


A multi-parameter system for use in neonatal resuscitation research and training.

Platten CR, Wood FE, Chambers IR.

J Med Eng Technol. 2013 Jan;37(1):22-7. doi: 10.3109/03091902.2012.728675. Epub 2012 Dec 8.


OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells.

Navarro P, Festuccia N, Colby D, Gagliardi A, Mullin NP, Zhang W, Karwacki-Neisius V, Osorno R, Kelly D, Robertson M, Chambers I.

EMBO J. 2012 Dec 12;31(24):4547-62. doi: 10.1038/emboj.2012.321. Epub 2012 Nov 23.


Surgical trial in traumatic intracerebral hemorrhage (STITCH(Trauma)): study protocol for a randomized controlled trial.

Gregson BA, Rowan EN, Mitchell PM, Unterberg A, McColl EM, Chambers IR, McNamee P, Mendelow AD.

Trials. 2012 Oct 16;13:193. doi: 10.1186/1745-6215-13-193.


Esrrb is a direct Nanog target gene that can substitute for Nanog function in pluripotent cells.

Festuccia N, Osorno R, Halbritter F, Karwacki-Neisius V, Navarro P, Colby D, Wong F, Yates A, Tomlinson SR, Chambers I.

Cell Stem Cell. 2012 Oct 5;11(4):477-90. doi: 10.1016/j.stem.2012.08.002.


Stem cell powwow in Squaw Valley.

Chambers I, Schroeder T.

Development. 2012 Jul;139(14):2457-61. doi: 10.1242/dev.079475.


Maxillary sarcomatoid carcinoma.

Verco S, Chambers I, Hall G.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Jul;114(1):e31-5. doi: 10.1016/j.oooo.2011.08.002. Epub 2012 Mar 3. No abstract available.


Bmi1 facilitates primitive endoderm formation by stabilizing Gata6 during early mouse development.

Lavial F, Bessonnard S, Ohnishi Y, Tsumura A, Chandrashekran A, Fenwick MA, Tomaz RA, Hosokawa H, Nakayama T, Chambers I, Hiiragi T, Chazaud C, Azuara V.

Genes Dev. 2012 Jul 1;26(13):1445-58. doi: 10.1101/gad.188193.112. Epub 2012 Jun 19.


The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression.

Osorno R, Tsakiridis A, Wong F, Cambray N, Economou C, Wilkie R, Blin G, Scotting PJ, Chambers I, Wilson V.

Development. 2012 Jul;139(13):2288-98. doi: 10.1242/dev.078071.


Trigger characteristics of EUSIG-defined hypotensive events.

Donald R, Howells T, Piper I, Chambers I, Citerio G, Enblad P, Gregson B, Kiening K, Mattern J, Nilsson P, Ragauskas A, Sahuquillo J, Sinnott R, Stell A.

Acta Neurochir Suppl. 2012;114:45-9. doi: 10.1007/978-3-7091-0956-4_9.


Early warning of EUSIG-defined hypotensive events using a Bayesian Artificial Neural Network.

Donald R, Howells T, Piper I, Chambers I, Citerio G, Enblad P, Gregson B, Kiening K, Mattern J, Nilsson P, Ragauskas A, Sahuquillo J, Sinnott R, Stell A.

Acta Neurochir Suppl. 2012;114:39-44. doi: 10.1007/978-3-7091-0956-4_8.


Quantification of pluripotency transcription factor levels in embryonic stem cells by flow cytometry.

Festuccia N, Chambers I.

Curr Protoc Stem Cell Biol. 2011 Dec;Chapter 1:Unit 1B.9. doi: 10.1002/9780470151808.sc01b09s19.


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