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Evaluation of a Paradigm Shift From Intravenous Antibiotics to Oral Step-Down Therapy for the Treatment of Infective Endocarditis: A Narrative Review.

Spellberg B, Chambers HF, Musher DM, Walsh TL, Bayer AS.

JAMA Intern Med. 2020 Mar 30. doi: 10.1001/jamainternmed.2020.0555. [Epub ahead of print]


Establishing surgical indications for hamstring lengthening and femoral derotational osteotomy in ambulatory children with cerebral palsy.

McCarthy J, Wade Shrader M, Graham K, Veerkamp M, Brower L, Chambers H, Davids JR, Kay RM, Narayanan U, Novacheck TF, Pierz K, Rhodes J, Rutz E, Shilt J, Shore BJ, Theologis T, Campenhout AV.

J Child Orthop. 2020 Feb 1;14(1):50-57. doi: 10.1302/1863-2548.14.190173. Review.


Molecular and clinical epidemiology of carbapenem-resistant Enterobacterales in the USA (CRACKLE-2): a prospective cohort study.

van Duin D, Arias CA, Komarow L, Chen L, Hanson BM, Weston G, Cober E, Garner OB, Jacob JT, Satlin MJ, Fries BC, Garcia-Diaz J, Doi Y, Dhar S, Kaye KS, Earley M, Hujer AM, Hujer KM, Domitrovic TN, Shropshire WC, Dinh A, Manca C, Luterbach CL, Wang M, Paterson DL, Banerjee R, Patel R, Evans S, Hill C, Arias R, Chambers HF, Fowler VG Jr, Kreiswirth BN, Bonomo RA; Multi-Drug Resistant Organism Network Investigators.

Lancet Infect Dis. 2020 Mar 6. pii: S1473-3099(19)30755-8. doi: 10.1016/S1473-3099(19)30755-8. [Epub ahead of print]


Knee pain in children with cerebral palsy.

Chambers HG.

Dev Med Child Neurol. 2020 Mar 2. doi: 10.1111/dmcn.14502. [Epub ahead of print] No abstract available.


Scope and Predictive Genetic/Phenotypic Signatures of 'Bicarbonate [NaHCO3]-Responsiveness' and β-Lactam Sensitization Among Methicillin-Resistant Staphylococcus aureus (MRSA).

Ersoy SC, Otmishi M, Milan VT, Li L, Pak Y, Mediavilla J, Chen L, Kreiswirth B, Chambers HF, Proctor RA, Xiong YQ, Fowler VG, Bayer AS.

Antimicrob Agents Chemother. 2020 Feb 10. pii: AAC.02445-19. doi: 10.1128/AAC.02445-19. [Epub ahead of print]


Prophylaxis for Pediatric Venous Thromboembolism: Current Status and Changes Across Pediatric Orthopaedic Society of North America From 2011.

Murphy RF, Williams D, Hogue GD, Spence DD, Epps H, Chambers HG, Shore BJ.

J Am Acad Orthop Surg. 2020 Jan 31. doi: 10.5435/JAAOS-D-19-00578. [Epub ahead of print]


Stable childhood osteochondral lesions of the talus: short-term radiographic outcomes suggest risk for early osteoarthritis.

Edmonds EW, Phillips L, Roocroft JH, Bastrom TP, Pennock AT, Chambers HG.

J Pediatr Orthop B. 2019 Dec 14. doi: 10.1097/BPB.0000000000000708. [Epub ahead of print]


Ability of Bicarbonate Supplementation To Sensitize Selected Methicillin-Resistant Staphylococcus aureus Strains to β-Lactam Antibiotics in an Ex Vivo Simulated Endocardial Vegetation Model.

Rose WE, Bienvenida AM, Xiong YQ, Chambers HF, Bayer AS, Ersoy SC.

Antimicrob Agents Chemother. 2020 Feb 21;64(3). pii: e02072-19. doi: 10.1128/AAC.02072-19. Print 2020 Feb 21.


Contribution of extracellular matrix components to the stiffness of skeletal muscle contractures in patients with cerebral palsy.

Smith LR, Pichika R, Meza RC, Gillies AR, Baliki MN, Chambers HG, Lieber RL.

Connect Tissue Res. 2019 Nov 28:1-12. doi: 10.1080/03008207.2019.1694011. [Epub ahead of print]


Simultaneous Evaluation of Diagnostic Assays for Pharyngeal and Rectal Neisseria gonorrhoeae and Chlamydia trachomatis Using a Master Protocol.

Doernberg SB, Komarow L, Tran TTT, Sund Z, Pandori MW, Jensen D, Tsalik EL, Deal CD, Chambers HF, Fowler VG, Evans SR, Patel R, Klausner JD; Antibacterial Resistance Leadership Group.

Clin Infect Dis. 2019 Nov 17. pii: ciz1105. doi: 10.1093/cid/ciz1105. [Epub ahead of print]


Antimicrobial Drug Development Efficiency and Surrogate Markers of Clinical Benefit.

Volberding P, Chambers HF.

JAMA Intern Med. 2019 Nov 11. doi: 10.1001/jamainternmed.2019.5441. [Epub ahead of print] No abstract available.


Is Daptomycin plus Ceftaroline Associated with Better Clinical Outcomes than Standard of Care Monotherapy for Staphylococcus aureus Bacteremia?

Kalil AC, Holubar M, Deresinski S, Chambers HF.

Antimicrob Agents Chemother. 2019 Oct 22;63(11). pii: e00900-19. doi: 10.1128/AAC.00900-19. Print 2019 Nov. No abstract available.


Transphyseal Anterior Cruciate Ligament Reconstruction in the Skeletally Immature: Quadriceps Tendon Autograft Versus Hamstring Tendon Autograft.

Pennock AT, Johnson KP, Turk RD, Bastrom TP, Chambers HG, Boutelle KE, Edmonds EW.

Orthop J Sports Med. 2019 Sep 17;7(9):2325967119872450. doi: 10.1177/2325967119872450. eCollection 2019 Sep.


Corrigendum to: 1757. Using the Desirability of Outcome Ranking for Management of Antimicrobial Therapy (DOOR-MAT) to Assess Antibiotic Therapy Guided by Rapid Molecular Diagnostics (RMD) in Bloodstream Infection (BSI) Caused by Escherichia coli and Klebsiella pneumonia.

Wilson B, Viau R, Perez F, Jiang H, Fowler VG Jr, Chambers HF, Kreiswirth BN, Bonomo RA, Evans SR; ARLG.

Open Forum Infect Dis. 2019 Jul 3;6(7):ofz267. doi: 10.1093/ofid/ofz267. eCollection 2019 Jul.


Prevalence, Patterns, and Cost of Care for Children with Cerebral Palsy Enrolled in Medicaid Managed Care.

Pulgar S, Bains S, Gooch J, Chambers H, Noritz GH, Wright E, Sawhney TG, Pyenson B, Ferro C.

J Manag Care Spec Pharm. 2019 Jul;25(7):817-822. doi: 10.18553/jmcp.2019.25.7.817.


The Natural History of Meniscus Tears.

Chambers HG, Chambers RC.

J Pediatr Orthop. 2019 Jul;39(Issue 6, Supplement 1 Suppl 1):S53-S55. doi: 10.1097/BPO.0000000000001386. Review.


The Emperor's New Clothes: Prospective Observational Evaluation of the Association between Initial Vancomycin Exposure and Failure Rates among Adult Hospitalized Patients with MRSA Bloodstream Infections (PROVIDE).

Lodise TP, Rosenkranz SL, Finnemeyer M, Evans S, Sims M, Zervos MJ, Creech CB, Patel PC, Keefer M, Riska P, Silveira FP, Scheetz M, Wunderink RG, Rodriguez M, Schrank J, Bleasdale SC, Schultz S, Barron M, Stapleton A, Wray D, Chambers H, Fowler V, Holland TL; Antibacterial Resistance Leadership Group.

Clin Infect Dis. 2019 Jun 3. pii: ciz460. doi: 10.1093/cid/ciz460. [Epub ahead of print]


Sustained Circulating Bacterial Deoxyribonucleic Acid Is Associated With Complicated Staphylococcus aureus Bacteremia.

Gutierrez J, Guimaraes AO, Lewin-Koh N, Berhanu A, Xu M, Cao Y, Kim J, Yan D, Chang JK, Dinoso JB, Koss CA, Clemenzi-Allen A, Chambers HF, Peck MC, Baruch A, Rosenberger CM.

Open Forum Infect Dis. 2019 Feb 26;6(4):ofz090. doi: 10.1093/ofid/ofz090. eCollection 2019 Apr.


Bicarbonate Resensitization of Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics.

Ersoy SC, Abdelhady W, Li L, Chambers HF, Xiong YQ, Bayer AS.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00496-19. doi: 10.1128/AAC.00496-19. Print 2019 Jul.


Outcomes of Revision Anterior Cruciate Ligament Surgery in Adolescents.

Ouillette R, Edmonds E, Chambers H, Bastrom T, Pennock A.

Am J Sports Med. 2019 May;47(6):1346-1352. doi: 10.1177/0363546519837173. Epub 2019 Apr 17.


Complexity of gait in a child with spasticity.

Chambers HG.

Dev Med Child Neurol. 2019 Oct;61(10):1123. doi: 10.1111/dmcn.14219. Epub 2019 Mar 25. No abstract available.


Omadacycline - The Newest Tetracycline.

Chambers HF.

N Engl J Med. 2019 Feb 7;380(6):588-589. doi: 10.1056/NEJMe1900188. No abstract available.


Clinical Practice Variation Among Adult Infectious Disease Physicians in the Management of Staphylococcus aureus Bacteremia.

Liu C, Strnad L, Beekmann SE, Polgreen PM, Chambers HF.

Clin Infect Dis. 2019 Jul 18;69(3):530-533. doi: 10.1093/cid/ciy1144.


Neuroprotection From Organophosphate-Induced Damage by Novel Phenoxyalkyl Pyridinium Oximes in Rat Brain.

Pringle RB, Meek EC, Chambers HW, Chambers JE.

Toxicol Sci. 2018 Dec 1;166(2):420-427. doi: 10.1093/toxsci/kfy212.


Recurrence of Patellar Instability in Adolescents Undergoing Surgery for Osteochondral Defects Without Concomitant Ligament Reconstruction.

Pedowitz JM, Edmonds EW, Chambers HG, Dennis MM, Bastrom T, Pennock AT.

Am J Sports Med. 2019 Jan;47(1):66-70. doi: 10.1177/0363546518808486. Epub 2018 Nov 28.


Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus.

Alexander JAN, Chatterjee SS, Hamilton SM, Eltis LD, Chambers HF, Strynadka NCJ.

J Biol Chem. 2018 Dec 21;293(51):19854-19865. doi: 10.1074/jbc.RA118.004952. Epub 2018 Oct 26.


Sequential, Multiple-Assignment, Randomized Trials for COMparing Personalized Antibiotic StrategieS (SMART-COMPASS).

Evans SR, Follmann D, Liu Y, Holland T, Doernberg SB, Rouphael N, Hamasaki T, Jiang Y, Lok JJ, Tran TTT, Harris AD, Fowler VG, Boucher H, Kreiswirth BN, Bonomo RA, Van Duin D, Paterson DL, Chambers H.

Clin Infect Dis. 2019 May 17;68(11):1961-1967. doi: 10.1093/cid/ciy912.


Good Studies Evaluate the Disease While Great Studies Evaluate the Patient: Development and Application of a Desirability of Outcome Ranking Endpoint for Staphylococcus aureus Bloodstream Infection.

Doernberg SB, Tran TTT, Tong SYC, Paul M, Yahav D, Davis JS, Leibovici L, Boucher HW, Corey GR, Cosgrove SE, Chambers HF, Fowler VG, Evans SR, Holland TL; Antibacterial Resistance Leadership Group.

Clin Infect Dis. 2019 May 2;68(10):1691-1698. doi: 10.1093/cid/ciy766.


Rapid Molecular Diagnostics to Inform Empiric Use of Ceftazidime/Avibactam and Ceftolozane/Tazobactam Against Pseudomonas aeruginosa: PRIMERS IV.

Evans SR, Tran TTT, Hujer AM, Hill CB, Hujer KM, Mediavilla JR, Manca C, Domitrovic TN, Perez F, Farmer M, Pitzer KM, Wilson BM, Kreiswirth BN, Patel R, Jacobs MR, Chen L, Fowler VG, Chambers HF, Bonomo RA; Antibacterial Resistance Leadership Group (ARLG).

Clin Infect Dis. 2019 May 17;68(11):1823-1830. doi: 10.1093/cid/ciy801.


Considerations for Clinical Trials of Staphylococcus aureus Bloodstream Infection in Adults.

Holland TL, Chambers HF, Boucher HW, Corey GR, Coleman R, Castaneda-Ruiz B, Fowler VG.

Clin Infect Dis. 2019 Feb 15;68(5):865-872. doi: 10.1093/cid/ciy774.


A Prognostic Model of Persistent Bacteremia and Mortality in Complicated Staphylococcus aureus Bloodstream Infection.

Guimaraes AO, Cao Y, Hong K, Mayba O, Peck MC, Gutierrez J, Ruffin F, Carrasco-Triguero M, Dinoso JB, Clemenzi-Allen A, Koss CA, Maskarinec SA, Chambers HF, Fowler VG, Baruch A, Rosenberger CM.

Clin Infect Dis. 2019 Apr 24;68(9):1502-1511. doi: 10.1093/cid/ciy739.


Use of a Modified All-Epiphyseal Technique for Anterior Cruciate Ligament Reconstruction in the Skeletally Immature Patient.

Pennock AT, Chambers HG, Turk RD, Parvanta KM, Dennis MM, Edmonds EW.

Orthop J Sports Med. 2018 Jul 2;6(7):2325967118781769. doi: 10.1177/2325967118781769. eCollection 2018 Jul.


PBP4: A New Perspective on Staphylococcus aureus β-Lactam Resistance.

da Costa TM, de Oliveira CR, Chambers HF, Chatterjee SS.

Microorganisms. 2018 Jun 22;6(3). pii: E57. doi: 10.3390/microorganisms6030057. Review.


In vitro P-glycoprotein activity does not completely explain in vivo efficacy of novel centrally effective oxime acetylcholinesterase reactivators.

Dail MB, Meek EC, Chambers HW, Chambers JE.

Drug Chem Toxicol. 2019 Jul;42(4):403-408. doi: 10.1080/01480545.2018.1461902. Epub 2018 May 3.


Loss of myogenic potential and fusion capacity of muscle stem cells isolated from contractured muscle in children with cerebral palsy.

Domenighetti AA, Mathewson MA, Pichika R, Sibley LA, Zhao L, Chambers HG, Lieber RL.

Am J Physiol Cell Physiol. 2018 Aug 1;315(2):C247-C257. doi: 10.1152/ajpcell.00351.2017. Epub 2018 Apr 25.


Duration and setting of rural immersion during the medical degree relates to rural work outcomes.

O'Sullivan B, McGrail M, Russell D, Walker J, Chambers H, Major L, Langham R.

Med Educ. 2018 Aug;52(8):803-815. doi: 10.1111/medu.13578. Epub 2018 Apr 19.


Essential Resources and Strategies for Antibiotic Stewardship Programs in the Acute Care Setting.

Doernberg SB, Abbo LM, Burdette SD, Fishman NO, Goodman EL, Kravitz GR, Leggett JE, Moehring RW, Newland JG, Robinson PA, Spivak ES, Tamma PD, Chambers HF.

Clin Infect Dis. 2018 Sep 28;67(8):1168-1174. doi: 10.1093/cid/ciy255.


Selective percutaneous muscle lengthening in cerebral palsy: when there is little or no evidence.

Chambers HG.

Dev Med Child Neurol. 2018 Apr;60(4):328. doi: 10.1111/dmcn.13698. No abstract available.


Mental health of unaccompanied asylum-seeking adolescents previously held in British detention centres.

Ehntholt KA, Trickey D, Harris Hendriks J, Chambers H, Scott M, Yule W.

Clin Child Psychol Psychiatry. 2018 Apr;23(2):238-257. doi: 10.1177/1359104518758839.


Invasive pneumococcal infections in pediatric liver-small bowel-pancreas transplant recipients.

Vo HD, Florescu DF, Brown CR, Chambers HE, Mercer DF, Vargas LM, Grant WJ, Langnas AN, Quiros-Tejeira RE.

Pediatr Transplant. 2018 May;22(3):e13165. doi: 10.1111/petr.13165. Epub 2018 Feb 13.


Ruralization of students' horizons: insights into Australian health professional students' rural and remote placements.

Smith T, Cross M, Waller S, Chambers H, Farthing A, Barraclough F, Pit SW, Sutton K, Muyambi K, King S, Anderson J.

J Multidiscip Healthc. 2018 Jan 31;11:85-97. doi: 10.2147/JMDH.S150623. eCollection 2018.


Cellulitis and Soft Tissue Infections.

Bystritsky R, Chambers H.

Ann Intern Med. 2018 Feb 6;168(3):ITC17-ITC32. doi: 10.7326/AITC201802060. Review.


A review of characteristics and outcomes of Australia's undergraduate medical education rural immersion programs.

O'Sullivan BG, McGrail MR, Russell D, Chambers H, Major L.

Hum Resour Health. 2018 Jan 31;16(1):8. doi: 10.1186/s12960-018-0271-2. Review.


PBP4 activity and its overexpression are necessary for PBP4-mediated high-level β-lactam resistance.

Basuino L, Jousselin A, Alexander JAN, Strynadka NCJ, Pinho MG, Chambers HF, Chatterjee SS.

J Antimicrob Chemother. 2018 May 1;73(5):1177-1180. doi: 10.1093/jac/dkx531.


A Trial of Antibiotics for Smaller Skin Abscesses.

Daum RS, Kumar N, Chambers HF.

N Engl J Med. 2017 Dec 28;377(26):e36. doi: 10.1056/NEJMc1711124. No abstract available.


Sulfamethoxazole-Trimethoprim (Cotrimoxazole) for Skin and Soft Tissue Infections Including Impetigo, Cellulitis, and Abscess.

Bowen AC, Carapetis JR, Currie BJ, Fowler V Jr, Chambers HF, Tong SYC.

Open Forum Infect Dis. 2017 Nov 2;4(4):ofx232. doi: 10.1093/ofid/ofx232. eCollection 2017 Fall. Review.


Reply to Paul and Leibovici.

Boucher HW, Ambrose PG, Chambers HF, Ebright RH, Jezek A, Murray BE, Ostrowsky B, Rex JH.

J Infect Dis. 2018 Jan 17;217(3):509-510. doi: 10.1093/infdis/jix537. No abstract available.


Perioperative Prophylaxis for Total Artificial Heart Transplantation.

Chambers HE, Pelish P, Qiu F, Florescu DF.

Transplant Proc. 2017 Nov;49(9):2169-2175. doi: 10.1016/j.transproceed.2017.09.020.


Professional, structural and organisational interventions in primary care for reducing medication errors.

Khalil H, Bell B, Chambers H, Sheikh A, Avery AJ.

Cochrane Database Syst Rev. 2017 Oct 4;10:CD003942. doi: 10.1002/14651858.CD003942.pub3. Review.


Disabling Dactylitis and Tenosynovitis Due to Mycobacterium haemophilum in a Patient With Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome.

Woodworth MH, Marquez C, Chambers H, Luetkemeyer A.

Open Forum Infect Dis. 2017 Sep 23;4(3):ofx165. doi: 10.1093/ofid/ofx165. eCollection 2017 Summer. No abstract available.

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