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Items: 40


Retromer revisited: Evolving roles for retromer in endosomal sorting.

Chamberland JP, Ritter B.

J Cell Biol. 2017 Nov 6;216(11):3433-3436. doi: 10.1083/jcb.201708111. Epub 2017 Oct 23.


Adiponectin administration prevents weight gain and glycemic profile changes in diet-induced obese immune deficient Rag1-/- mice lacking mature lymphocytes.

Liu X, Perakakis N, Gong H, Chamberland JP, Brinkoetter MT, Hamnvik OR, Mantzoros CS.

Metabolism. 2016 Dec;65(12):1720-1730. doi: 10.1016/j.metabol.2016.09.003. Epub 2016 Sep 22.


NECAP2 controls clathrin coat recruitment to early endosomes for fast endocytic recycling.

Chamberland JP, Antonow LT, Dias Santos M, Ritter B.

J Cell Sci. 2016 Jul 1;129(13):2625-37. doi: 10.1242/jcs.173708. Epub 2016 May 20.


Lack of mature lymphocytes results in obese but metabolically healthy mice when fed a high-fat diet.

Liu X, Huh JY, Gong H, Chamberland JP, Brinkoetter MT, Hamnvik OP, Mantzoros CS.

Int J Obes (Lond). 2015 Oct;39(10):1548-57. doi: 10.1038/ijo.2015.93. Epub 2015 May 21.


Lack of Day/Night variation in fibroblast growth factor 21 levels in young healthy men.

Foo JP, Aronis KN, Chamberland JP, Mantzoros CS.

Int J Obes (Lond). 2015 Jun;39(6):945-8. doi: 10.1038/ijo.2014.215. Epub 2014 Dec 26.


Down-regulation of malignant potential by alpha linolenic acid in human and mouse colon cancer cells.

Chamberland JP, Moon HS.

Fam Cancer. 2015 Mar;14(1):25-30. doi: 10.1007/s10689-014-9762-z.


Circulating irisin levels and coronary heart disease: association with future acute coronary syndrome and major adverse cardiovascular events.

Aronis KN, Moreno M, Polyzos SA, Moreno-Navarrete JM, Ricart W, Delgado E, de la Hera J, Sahin-Efe A, Chamberland JP, Berman R, Spiro A 3rd, Vokonas P, Fernández-Real JM, Mantzoros CS.

Int J Obes (Lond). 2015 Jan;39(1):156-61. doi: 10.1038/ijo.2014.101. Epub 2013 Jun 11.


Circulating alanine transaminase (ALT) and γ-glutamyl transferase (GGT), but not fetuin-A, are associated with metabolic risk factors, at baseline and at two-year follow-up: the prospective Cyprus Metabolism Study.

Liu X, Hamnvik OP, Chamberland JP, Petrou M, Gong H, Christophi CA, Christiani DC, Kales SN, Mantzoros CS.

Metabolism. 2014 Jun;63(6):773-82. doi: 10.1016/j.metabol.2014.03.008. Epub 2014 Mar 15.


Circulating fetuin-A levels are not affected by short and long-term energy deprivation and/or by leptin administration.

Hwang JJ, Thakkar B, Chamberland JP, Mantzoros CS.

Metabolism. 2014 Jun;63(6):754-9. doi: 10.1016/j.metabol.2014.02.006. Epub 2014 Feb 17.


Chemerin levels as predictor of acute coronary events: a case-control study nested within the veterans affairs normative aging study.

Aronis KN, Sahin-Efe A, Chamberland JP, Spiro A 3rd, Vokonas P, Mantzoros CS.

Metabolism. 2014 Jun;63(6):760-6. doi: 10.1016/j.metabol.2014.02.013. Epub 2014 Feb 25.


Irisin mRNA and circulating levels in relation to other myokines in healthy and morbidly obese humans.

Vamvini MT, Aronis KN, Panagiotou G, Huh JY, Chamberland JP, Brinkoetter MT, Petrou M, Christophi CA, Kales SN, Christiani DC, Mantzoros CS.

Eur J Endocrinol. 2013 Oct 21;169(6):829-34. doi: 10.1530/EJE-13-0276. Print 2013 Dec.


Chemerin is expressed mainly in pancreas and liver, is regulated by energy deprivation, and lacks day/night variation in humans.

Chamberland JP, Berman RL, Aronis KN, Mantzoros CS.

Eur J Endocrinol. 2013 Sep 13;169(4):453-62. doi: 10.1530/EJE-13-0098. Print 2013 Oct.


GLP-1 promotes angiogenesis in human endothelial cells in a dose-dependent manner, through the Akt, Src and PKC pathways.

Aronis KN, Chamberland JP, Mantzoros CS.

Metabolism. 2013 Sep;62(9):1279-86. doi: 10.1016/j.metabol.2013.04.010. Epub 2013 May 14.


Gender dimorphism and lack of day/night variation or effects of energy deprivation on undercarboxylated osteocalcin levels in humans.

Foo JP, Aronis KN, Chamberland JP, Thakkar B, Hamnvik OP, Brinkoetter M, Zaichenko L, Mantzoros CS.

Obesity (Silver Spring). 2013 Dec;21(12):E527-32. doi: 10.1002/oby.20453. Epub 2013 Jun 13.


Abdominal obesity, independent from caloric intake, accounts for the development of intestinal tumors in Apc(1638N/+) female mice.

Huffman DM, Augenlicht LH, Zhang X, Lofrese JJ, Atzmon G, Chamberland JP, Mantzoros CS.

Cancer Prev Res (Phila). 2013 Mar;6(3):177-87. doi: 10.1158/1940-6207.CAPR-12-0414.


Fibroblast growth factor 21 levels in young healthy females display day and night variations and are increased in response to short-term energy deprivation through a leptin-independent pathway.

Foo JP, Aronis KN, Chamberland JP, Paruthi J, Moon HS, Mantzoros CS.

Diabetes Care. 2013 Apr;36(4):935-42. doi: 10.2337/dc12-0497. Epub 2012 Nov 27.


Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice.

Moon HS, Liu X, Nagel JM, Chamberland JP, Diakopoulos KN, Brinkoetter MT, Hatziapostolou M, Wu Y, Robson SC, Iliopoulos D, Mantzoros CS.

Gut. 2013 Apr;62(4):561-70. doi: 10.1136/gutjnl-2012-302092. Epub 2012 Jun 26.


Secretion patterns of circulating osteoprotegerin and response to acute and chronic energy deprivation in young healthy adults.

Aronis KN, Foo JP, Chamberland JP, Mantzoros CS.

J Clin Endocrinol Metab. 2012 Aug;97(8):2765-72. doi: 10.1210/jc.2012-1618. Epub 2012 May 4.


Amylin and leptin activate overlapping signalling pathways in an additive manner in mouse GT1-7 hypothalamic, C₂C₁₂ muscle and AML12 liver cell lines.

Moon HS, Chamberland JP, Mantzoros CS.

Diabetologia. 2012 Jan;55(1):215-25. doi: 10.1007/s00125-011-2332-0. Epub 2011 Oct 14.


Direct role of adiponectin and adiponectin receptors in endometrial cancer: in vitro and ex vivo studies in humans.

Moon HS, Chamberland JP, Aronis K, Tseleni-Balafouta S, Mantzoros CS.

Mol Cancer Ther. 2011 Dec;10(12):2234-43. doi: 10.1158/1535-7163.MCT-11-0545. Epub 2011 Oct 6.


Insulin resistance in relation to melanoma risk.

Antoniadis AG, Petridou ET, Antonopoulos CN, Dessypris N, Panagopoulou P, Chamberland JP, Adami HO, Gogas H, Mantzoros CS.

Melanoma Res. 2011 Dec;21(6):541-6. doi: 10.1097/CMR.0b013e32834b0eeb.


Circulating adiponectin is inversely associated with risk of thyroid cancer: in vivo and in vitro studies.

Mitsiades N, Pazaitou-Panayiotou K, Aronis KN, Moon HS, Chamberland JP, Liu X, Diakopoulos KN, Kyttaris V, Panagiotou V, Mylvaganam G, Tseleni-Balafouta S, Mantzoros CS.

J Clin Endocrinol Metab. 2011 Dec;96(12):E2023-8. doi: 10.1210/jc.2010-1908. Epub 2011 Sep 21.


Short-term energy deprivation alters activin a and follistatin but not inhibin B levels of lean healthy women in a leptin-independent manner.

Moragianni VA, Aronis KN, Chamberland JP, Mantzoros CS.

J Clin Endocrinol Metab. 2011 Dec;96(12):3750-8. doi: 10.1210/jc.2011-1453. Epub 2011 Sep 14.


Circulating clusterin (apolipoprotein J) levels do not have any day/night variability and are positively associated with total and LDL cholesterol levels in young healthy individuals.

Aronis KN, Vamvini MT, Chamberland JP, Mantzoros CS.

J Clin Endocrinol Metab. 2011 Nov;96(11):E1871-5. doi: 10.1210/jc.2011-1555. Epub 2011 Sep 7.


Circulating lipocalin 2 is associated with body fat distribution at baseline but is not an independent predictor of insulin resistance: the prospective Cyprus Metabolism Study.

Liu X, Hamnvik OP, Petrou M, Gong H, Chamberland JP, Christophi CA, Kales SN, Christiani DC, Mantzoros CS.

Eur J Endocrinol. 2011 Nov;165(5):805-12. doi: 10.1530/EJE-11-0660. Epub 2011 Sep 1.


Energy deprivation alters in a leptin- and cortisol-independent manner circulating levels of activin A and follistatin but not myostatin in healthy males.

Vamvini MT, Aronis KN, Chamberland JP, Mantzoros CS.

J Clin Endocrinol Metab. 2011 Nov;96(11):3416-23. doi: 10.1210/jc.2011-1665. Epub 2011 Aug 24.


Preadipocyte factor-1 levels are higher in women with hypothalamic amenorrhea and are associated with bone mineral content and bone mineral density through a mechanism independent of leptin.

Aronis KN, Kilim H, Chamberland JP, Breggia A, Rosen C, Mantzoros CS.

J Clin Endocrinol Metab. 2011 Oct;96(10):E1634-9. doi: 10.1210/jc.2011-0600. Epub 2011 Jul 27.


Dietary walnuts inhibit colorectal cancer growth in mice by suppressing angiogenesis.

Nagel JM, Brinkoetter M, Magkos F, Liu X, Chamberland JP, Shah S, Zhou J, Blackburn G, Mantzoros CS.

Nutrition. 2012 Jan;28(1):67-75. doi: 10.1016/j.nut.2011.03.004. Epub 2011 Jul 27.


Adiponectin receptor expression in human malignant tissues.

Chou SH, Tseleni-Balafouta S, Moon HS, Chamberland JP, Liu X, Kavantzas N, Mantzoros CS.

Horm Cancer. 2010 Jun;1(3):136-45. doi: 10.1007/s12672-010-0017-7.


Long-term metreleptin treatment increases bone mineral density and content at the lumbar spine of lean hypoleptinemic women.

Sienkiewicz E, Magkos F, Aronis KN, Brinkoetter M, Chamberland JP, Chou S, Arampatzi KM, Gao C, Koniaris A, Mantzoros CS.

Metabolism. 2011 Sep;60(9):1211-21. doi: 10.1016/j.metabol.2011.05.016. Epub 2011 Jul 7.


Leptin administered in physiological or pharmacological doses does not regulate circulating angiogenesis factors in humans.

Aronis KN, Diakopoulos KN, Fiorenza CG, Chamberland JP, Mantzoros CS.

Diabetologia. 2011 Sep;54(9):2358-67. doi: 10.1007/s00125-011-2201-x. Epub 2011 Jun 10.


Efficacy of metreleptin in obese patients with type 2 diabetes: cellular and molecular pathways underlying leptin tolerance.

Moon HS, Matarese G, Brennan AM, Chamberland JP, Liu X, Fiorenza CG, Mylvaganam GH, Abanni L, Carbone F, Williams CJ, De Paoli AM, Schneider BE, Mantzoros CS.

Diabetes. 2011 Jun;60(6):1647-56. doi: 10.2337/db10-1791.


Leptin is an effective treatment for hypothalamic amenorrhea.

Chou SH, Chamberland JP, Liu X, Matarese G, Gao C, Stefanakis R, Brinkoetter MT, Gong H, Arampatzi K, Mantzoros CS.

Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6585-90. doi: 10.1073/pnas.1015674108. Epub 2011 Apr 4.


Caffeinated coffee does not acutely affect energy intake, appetite, or inflammation but prevents serum cortisol concentrations from falling in healthy men.

Gavrieli A, Yannakoulia M, Fragopoulou E, Margaritopoulos D, Chamberland JP, Kaisari P, Kavouras SA, Mantzoros CS.

J Nutr. 2011 Apr 1;141(4):703-7. doi: 10.3945/jn.110.137323. Epub 2011 Feb 23.


Soluble leptin receptor and leptin are associated with baseline adiposity and metabolic risk factors, and predict adiposity, metabolic syndrome, and glucose levels at 2-year follow-up: the Cyprus Metabolism Prospective Cohort Study.

Hamnvik OP, Liu X, Petrou M, Gong H, Chamberland JP, Kim EH, Christophi CA, Kales SN, Christiani DC, Mantzoros CS.

Metabolism. 2011 Jul;60(7):987-93. doi: 10.1016/j.metabol.2010.09.009. Epub 2010 Nov 5.


Leptin and amylin act in an additive manner to activate overlapping signaling pathways in peripheral tissues: in vitro and ex vivo studies in humans.

Moon HS, Chamberland JP, Diakopoulos KN, Fiorenza CG, Ziemke F, Schneider B, Mantzoros CS.

Diabetes Care. 2011 Jan;34(1):132-8. doi: 10.2337/dc10-0518. Epub 2010 Sep 24.


Leptin in human physiology and therapeutics.

Dardeno TA, Chou SH, Moon HS, Chamberland JP, Fiorenza CG, Mantzoros CS.

Front Neuroendocrinol. 2010 Jul;31(3):377-93. doi: 10.1016/j.yfrne.2010.06.002. Epub 2010 Jun 17. Review.


Short-term treatment with ezetimibe, simvastatin or their combination does not alter circulating adiponectin, resistin or leptin levels in healthy men.

Gouni-Berthold I, Berthold HK, Chamberland JP, Krone W, Mantzoros CS.

Clin Endocrinol (Oxf). 2008 Apr;68(4):536-41. Epub 2007 Oct 31.


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