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Items: 26

1.

Soil properties and sediment accretion modulate methane fluxes from restored wetlands.

Chamberlain SD, Anthony TL, Silver WL, Eichelmann E, Hemes KS, Oikawa PY, Sturtevant C, Szutu DJ, Verfaillie JG, Baldocchi DD.

Glob Chang Biol. 2018 Sep;24(9):4107-4121. doi: 10.1111/gcb.14124. Epub 2018 Apr 10.

PMID:
29575340
2.

Making ecological models adequate.

Getz WM, Marshall CR, Carlson CJ, Giuggioli L, Ryan SJ, RomaƱach SS, Boettiger C, Chamberlain SD, Larsen L, D'Odorico P, O'Sullivan D.

Ecol Lett. 2018 Feb;21(2):153-166. doi: 10.1111/ele.12893. Epub 2017 Dec 27.

3.

Grazing alters net ecosystem C fluxes and the global warming potential of a subtropical pasture.

Gomez-Casanovas N, DeLucia NJ, Bernacchi CJ, Boughton EH, Sparks JP, Chamberlain SD, DeLucia EH.

Ecol Appl. 2018 Mar;28(2):557-572. doi: 10.1002/eap.1670. Epub 2018 Feb 27.

PMID:
29280238
4.

The Gulfwatch contaminants monitoring program in the Gulf of Maine: Are its data being used for ocean protection, with special reference to Nova Scotia, Canada?

Chamberlain SD, Wells PG, MacDonald BH.

Mar Pollut Bull. 2018 Feb;127:781-787. doi: 10.1016/j.marpolbul.2017.09.050. Epub 2017 Oct 3.

PMID:
28986110
5.

The impact of water management practices on subtropical pasture methane emissions and ecosystem service payments.

Chamberlain SD, Groffman PM, Boughton EH, Gomez-Casanovas N, DeLucia EH, Bernacchi CJ, Sparks JP.

Ecol Appl. 2017 Jun;27(4):1199-1209. doi: 10.1002/eap.1514. Epub 2017 Mar 28.

PMID:
28140494
6.

Sourcing methane and carbon dioxide emissions from a small city: Influence of natural gas leakage and combustion.

Chamberlain SD, Ingraffea AR, Sparks JP.

Environ Pollut. 2016 Nov;218:102-110. doi: 10.1016/j.envpol.2016.08.036. Epub 2016 Aug 20.

PMID:
27552043
7.

Biogeography of planktonic and benthic cyanobacteria in coastal waters of the Big Island, Hawai'i.

Chamberlain SD, Kaplan KA, Modanu M, Sirianni KM, Annandale S, Hewson I.

FEMS Microbiol Ecol. 2014 Jul;89(1):80-8. doi: 10.1111/1574-6941.12337. Epub 2014 Apr 29.

8.

GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers.

Sabbatini P, Korenchuk S, Rowand JL, Groy A, Liu Q, Leperi D, Atkins C, Dumble M, Yang J, Anderson K, Kruger RG, Gontarek RR, Maksimchuk KR, Suravajjala S, Lapierre RR, Shotwell JB, Wilson JW, Chamberlain SD, Rabindran SK, Kumar R.

Mol Cancer Ther. 2009 Oct;8(10):2811-20. doi: 10.1158/1535-7163.MCT-09-0423.

9.

Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase.

Patnaik S, Stevens KL, Gerding R, Deanda F, Shotwell JB, Tang J, Hamajima T, Nakamura H, Leesnitzer MA, Hassell AM, Shewchuck LM, Kumar R, Lei H, Chamberlain SD.

Bioorg Med Chem Lett. 2009 Jun 1;19(11):3136-40. doi: 10.1016/j.bmcl.2008.12.110. Epub 2009 Jan 6.

PMID:
19394223
10.

Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding.

Emmitte KA, Adjabeng GM, Andrews CW, Alberti JG, Bambal R, Chamberlain SD, Davis-Ward RG, Dickson HD, Hassler DF, Hornberger KR, Jackson JR, Kuntz KW, Lansing TJ, Mook RA Jr, Nailor KE, Pobanz MA, Smith SC, Sung CM, Cheung M.

Bioorg Med Chem Lett. 2009 Mar 15;19(6):1694-7. doi: 10.1016/j.bmcl.2009.01.094. Epub 2009 Jan 31. Erratum in: Bioorg Med Chem Lett. 2009 May 1;19(9):2604. Adjebang, George M [corrected to Adjabeng, George M].

PMID:
19237286
11.

Optimization of a series of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine inhibitors of IGF-1R: elimination of an acid-mediated decomposition pathway.

Chamberlain SD, Redman AM, Patnaik S, Brickhouse K, Chew YC, Deanda F, Gerding R, Lei H, Moorthy G, Patrick M, Stevens KL, Wilson JW, Brad Shotwell J.

Bioorg Med Chem Lett. 2009 Jan 15;19(2):373-7. doi: 10.1016/j.bmcl.2008.11.065. Epub 2008 Nov 24.

PMID:
19081716
12.

Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity.

Chamberlain SD, Redman AM, Wilson JW, Deanda F, Shotwell JB, Gerding R, Lei H, Yang B, Stevens KL, Hassell AM, Shewchuk LM, Leesnitzer MA, Smith JL, Sabbatini P, Atkins C, Groy A, Rowand JL, Kumar R, Mook RA Jr, Moorthy G, Patnaik S.

Bioorg Med Chem Lett. 2009 Jan 15;19(2):360-4. doi: 10.1016/j.bmcl.2008.11.077. Epub 2008 Nov 24.

PMID:
19071018
13.

Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: potent inhibitors of the IGF-1R receptor tyrosine kinase.

Chamberlain SD, Wilson JW, Deanda F, Patnaik S, Redman AM, Yang B, Shewchuk L, Sabbatini P, Leesnitzer MA, Groy A, Atkins C, Gerding R, Hassell AM, Lei H, Mook RA Jr, Moorthy G, Rowand JL, Stevens KL, Kumar R, Shotwell JB.

Bioorg Med Chem Lett. 2009 Jan 15;19(2):469-73. doi: 10.1016/j.bmcl.2008.11.046. Epub 2008 Nov 18.

PMID:
19056263
14.

Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines as EGFR and ErbB-2 inhibitors.

Stevens KL, Alligood KJ, Alberti JG, Caferro TR, Chamberlain SD, Dickerson SH, Dickson HD, Emerson HK, Griffin RJ, Hubbard RD, Keith BR, Mullin RJ, Petrov KG, Gerding RM, Reno MJ, Rheault TR, Rusnak DW, Sammond DM, Smith SC, Uehling DE, Waterson AG, Wood ER.

Bioorg Med Chem Lett. 2009 Jan 1;19(1):21-6. doi: 10.1016/j.bmcl.2008.11.023. Epub 2008 Nov 13.

PMID:
19028424
15.

Reversible carboxamide-mediated internal activation at C(6) of 2-chloro-4-anilino-1H-pyrrolo[2,3-d]pyrimidines.

Chamberlain SD, Gerding RM, Lei H, Moorthy G, Patnaik S, Redman AM, Stevens KL, Wilson JW, Yang B, Shotwell JB.

J Org Chem. 2008 Dec 5;73(23):9511-4. doi: 10.1021/jo8020693.

PMID:
18998728
16.

The identification of pyrazolo[1,5-a]pyridines as potent p38 kinase inhibitors.

Cheung M, Harris PA, Badiang JG, Peckham GE, Chamberlain SD, Alberti MJ, Jung DK, Harris SS, Bramson NH, Epperly AH, Stimpson SA, Peel MR.

Bioorg Med Chem Lett. 2008 Oct 15;18(20):5428-30. doi: 10.1016/j.bmcl.2008.09.040. Epub 2008 Sep 12.

PMID:
18818075
17.

Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats.

Conway JG, Pink H, Bergquist ML, Han B, Depee S, Tadepalli S, Lin P, Crumrine RC, Binz J, Clark RL, Selph JL, Stimpson SA, Hutchins JT, Chamberlain SD, Brodie TA.

J Pharmacol Exp Ther. 2008 Jul;326(1):41-50. doi: 10.1124/jpet.107.129429. Epub 2008 Apr 23.

PMID:
18434589
18.

Synthesis of novel anilinoquinolines as c-fms inhibitors.

Smalley TL Jr, Chamberlain SD, Mills WY, Musso DL, Randhawa SA, Ray JA, Samano V, Frick L.

Bioorg Med Chem Lett. 2007 Nov 15;17(22):6257-60. Epub 2007 Sep 7.

PMID:
17870531
19.

Pleistocene to recent dietary shifts in California condors.

Chamberlain CP, Waldbauer JR, Fox-Dobbs K, Newsome SD, Koch PL, Smith DR, Church ME, Chamberlain SD, Sorenson KJ, Risebrough R.

Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16707-11. Epub 2005 Nov 7.

20.

Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.

Conway JG, McDonald B, Parham J, Keith B, Rusnak DW, Shaw E, Jansen M, Lin P, Payne A, Crosby RM, Johnson JH, Frick L, Lin MH, Depee S, Tadepalli S, Votta B, James I, Fuller K, Chambers TJ, Kull FC, Chamberlain SD, Hutchins JT.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16078-83. Epub 2005 Oct 25.

21.

Pyrazolo[1,5-a]pyridines as p38 kinase inhibitors.

Stevens KL, Jung DK, Alberti MJ, Badiang JG, Peckham GE, Veal JM, Cheung M, Harris PA, Chamberlain SD, Peel MR.

Org Lett. 2005 Oct 13;7(21):4753-6.

PMID:
16209527
22.

Synthesis and evaluation of a series of 2'-deoxy analogues of the antiviral agent 5,6-dichloro-2-isopropylamino-1-(beta-L-ribofuranosyl)-1H-benzimidazole (1263W94).

Chan JH, Chamberlain SD, Biron KK, Davis MG, Harvey RJ, Selleseth DW, Dornsife RE, Dark EH, Frick LW, Townsend LB, Drach JC, Koszalka GW.

Nucleosides Nucleotides Nucleic Acids. 2000 Jan-Feb;19(1-2):101-23. Erratum in: Nucleosides Nucleotides Nucleic Acids. 2002;21(1):109.

PMID:
10772705
23.

Studies designed to increase the stability and antiviral activity (HCMV) of the active benzimidazole nucleoside, TCRB.

Townsend LB, Gudmundsson KS, Daluge SM, Chen JJ, Zhu Z, Koszalka GW, Boyd L, Chamberlain SD, Freeman GA, Biron KK, Drach JC.

Nucleosides Nucleotides. 1999 Apr-May;18(4-5):509-19.

PMID:
10432642
24.

Design, synthesis, and antiviral activity of alpha-nucleosides: D- and L-isomers of lyxofuranosyl- and (5-deoxylyxofuranosyl)benzimidazoles.

Migawa MT, Girardet JL, Walker JA 2nd, Koszalka GW, Chamberlain SD, Drach JC, Townsend LB.

J Med Chem. 1998 Apr 9;41(8):1242-51.

PMID:
9575044
25.

An enantiospecific synthesis of the human cytomegalovirus antiviral agent [(R)-3-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)-4- hydroxybutyl]phosphonic acid.

Chamberlain SD, Biron KK, Dornsife RE, Averett DR, Beauchamp L, Koszalka GW.

J Med Chem. 1994 Apr 29;37(9):1371-7.

PMID:
8176714
26.

Di- and triester prodrugs of the varicella-zoster antiviral agent 6-methoxypurine arabinoside.

Jones LA, Moorman AR, Chamberlain SD, de Miranda P, Reynolds DJ, Burns CL, Krenitsky TA.

J Med Chem. 1992 Jan;35(1):56-63.

PMID:
1732533

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