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Items: 11

1.

Synthesis and Bioactivity of a Brasilicardin A Analogue Featuring a Simplified Core.

Jung ME, Chamberlain BT, Koch P, Niazi KR.

Org Lett. 2015 Jul 17;17(14):3608-11. doi: 10.1021/acs.orglett.5b01712. Epub 2015 Jul 6.

PMID:
26144210
2.

The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice.

Hong C, Marshall SM, McDaniel AL, Graham M, Layne JD, Cai L, Scotti E, Boyadjian R, Kim J, Chamberlain BT, Tangirala RK, Jung ME, Fong L, Lee R, Young SG, Temel RE, Tontonoz P.

Cell Metab. 2014 Nov 4;20(5):910-918. doi: 10.1016/j.cmet.2014.10.001. Epub 2014 Nov 4.

3.

Structure-Activity Relationship of Semicarbazone EGA Furnishes Photoaffinity Inhibitors of Anthrax Toxin Cellular Entry.

Jung ME, Chamberlain BT, Ho CL, Gillespie EJ, Bradley KA.

ACS Med Chem Lett. 2014 Jan 21;5(4):363-7. doi: 10.1021/ml400486k. eCollection 2014 Apr 10.

4.

The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis.

Sallam T, Ito A, Rong X, Kim J, van Stijn C, Chamberlain BT, Jung ME, Chao LC, Jones M, Gilliland T, Wu X, Su GL, Tangirala RK, Tontonoz P, Hong C.

J Lipid Res. 2014 Jun;55(6):1120-30. doi: 10.1194/jlr.M047548. Epub 2014 Mar 26.

5.

Transition state in DNA polymerase β catalysis: rate-limiting chemistry altered by base-pair configuration.

Oertell K, Chamberlain BT, Wu Y, Ferri E, Kashemirov BA, Beard WA, Wilson SH, McKenna CE, Goodman MF.

Biochemistry. 2014 Mar 25;53(11):1842-8. doi: 10.1021/bi500101z. Epub 2014 Mar 12.

6.

LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition.

Rong X, Albert CJ, Hong C, Duerr MA, Chamberlain BT, Tarling EJ, Ito A, Gao J, Wang B, Edwards PA, Jung ME, Ford DA, Tontonoz P.

Cell Metab. 2013 Nov 5;18(5):685-97. doi: 10.1016/j.cmet.2013.10.002.

7.

Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses.

Gillespie EJ, Ho CL, Balaji K, Clemens DL, Deng G, Wang YE, Elsaesser HJ, Tamilselvam B, Gargi A, Dixon SD, France B, Chamberlain BT, Blanke SR, Cheng G, de la Torre JC, Brooks DG, Jung ME, Colicelli J, Damoiseaux R, Bradley KA.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):E4904-12. doi: 10.1073/pnas.1302334110. Epub 2013 Nov 4.

8.

An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity.

Williams KJ, Argus JP, Zhu Y, Wilks MQ, Marbois BN, York AG, Kidani Y, Pourzia AL, Akhavan D, Lisiero DN, Komisopoulou E, Henkin AH, Soto H, Chamberlain BT, Vergnes L, Jung ME, Torres JZ, Liau LM, Christofk HR, Prins RM, Mischel PS, Reue K, Graeber TG, Bensinger SJ.

Cancer Res. 2013 May 1;73(9):2850-62. doi: 10.1158/0008-5472.CAN-13-0382-T. Epub 2013 Feb 25.

9.

Stereospecific formation of a ternary complex of (S)-α,β-fluoromethylene-dATP with DNA pol β.

Chamberlain BT, Batra VK, Beard WA, Kadina AP, Shock DD, Kashemirov BA, McKenna CE, Goodman MF, Wilson SH.

Chembiochem. 2012 Mar 5;13(4):528-30. doi: 10.1002/cbic.201100738. Epub 2012 Feb 7.

10.

Synthesis and sensing of bisphosphonophosphate alkyl monoesters: A novel class of compounds for the study of nucleoside 5'-triphosphate chemistry.

Chamberlain BT, Osuna J, Kashemirov BA, McKenna CE.

Phosphorus Sulfur Silicon Relat Elem. 2011 Apr 1;186(4):966-967.

11.

α-Azido bisphosphonates: synthesis and nucleotide analogues.

Chamberlain BT, Upton TG, Kashemirov BA, McKenna CE.

J Org Chem. 2011 Jun 17;76(12):5132-6. doi: 10.1021/jo200045a. Epub 2011 May 25.

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