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Items: 1 to 50 of 107

1.

Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens.

Normand S, Waldschmitt N, Neerincx A, Martinez-Torres RJ, Chauvin C, Couturier-Maillard A, Boulard O, Cobret L, Awad F, Huot L, Ribeiro-Ribeiro A, Lautz K, Ruez R, Delacre M, Bondu C, Guilliams M, Scott C, Segal A, Amselem S, Hot D, Karabina S, Bohn E, Ryffel B, Poulin LF, Kufer TA, Chamaillard M.

Nat Commun. 2018 Dec 17;9(1):5338. doi: 10.1038/s41467-018-07750-5.

2.

Correction: Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation.

Couturier-Maillard A, Froux N, Piotet-Morin J, Michaudel C, Brault L, Le Bérichel J, Sénéchal A, Robinet P, Chenuet P, Jejou S, Dumoutier L, Renauld JC, Iovanna J, Huber S, Chamaillard M, Quesniaux VFJ, Sokol H, Ryffel B.

Mucosal Immunol. 2019 Jan;12(1):290. doi: 10.1038/s41385-018-0112-6.

PMID:
30504789
3.

The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection.

Hara H, Seregin SS, Yang D, Fukase K, Chamaillard M, Alnemri ES, Inohara N, Chen GY, Núñez G.

Cell. 2018 Nov 29;175(6):1651-1664.e14. doi: 10.1016/j.cell.2018.09.047. Epub 2018 Nov 1.

PMID:
30392956
4.

The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure.

Waldschmitt N, Kitamoto S, Secher T, Zacharioudaki V, Boulard O, Floquet E, Delacre M, Lamas B, Pham HP, Six A, Richard ML, Dagorn JC, Eberl G, Langella P, Chatel JM, Ryffel B, Iovanna JL, Poulin LF, Sokol H, Kamada N, Chamaillard M.

Gut. 2019 Jul;68(7):1190-1199. doi: 10.1136/gutjnl-2018-316757. Epub 2018 Oct 2.

PMID:
30279238
5.

MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype.

Plantamura E, Dzutsev A, Chamaillard M, Djebali S, Moudombi L, Boucinha L, Grau M, Macari C, Bauché D, Dumitrescu O, Rasigade JP, Lippens S, Plateroti M, Kress E, Cesaro A, Bondu C, Rothermel U, Heikenwälder M, Lina G, Bentaher-Belaaouaj A, Marie JC, Caux C, Trinchieri G, Marvel J, Michallet MC.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10404-10409. doi: 10.1073/pnas.1722372115. Epub 2018 Sep 24.

6.

Understanding the Cellular Origin of the Mononuclear Phagocyte System Sheds Light on the Myeloid Postulate of Immune Paralysis in Sepsis.

Poulin LF, Lasseaux C, Chamaillard M.

Front Immunol. 2018 Apr 24;9:823. doi: 10.3389/fimmu.2018.00823. eCollection 2018. Review.

7.

Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation.

Couturier-Maillard A, Froux N, Piotet-Morin J, Michaudel C, Brault L, Le Bérichel J, Sénéchal A, Robinet P, Chenuet P, Jejou S, Dumoutier L, Renauld JC, Iovanna J, Huber S, Chamaillard M, Quesniaux V, Sokol H, Chamaillard M, Ryffel B.

Mucosal Immunol. 2018 Jul;11(4):1181-1190. doi: 10.1038/s41385-018-0005-8. Epub 2018 May 4. Erratum in: Mucosal Immunol. 2019 Jan;12(1):290.

PMID:
29728643
8.

Integrin a6 loss promotes colitis-associated colorectal cancer. Response to: "Integrin a6 variants and colorectal cancer" by Beaulieu JF.

De Arcangelis A, Chamaillard M, Simon-Assmann P, Labouesse M.

Gut. 2018 Dec;67(12):2227-2228. doi: 10.1136/gutjnl-2017-315727. Epub 2018 Jan 3. No abstract available.

PMID:
29298874
9.

Type I interferons drive inflammasome-independent emergency monocytopoiesis during endotoxemia.

Lasseaux C, Fourmaux MP, Chamaillard M, Poulin LF.

Sci Rep. 2017 Dec 5;7(1):16935. doi: 10.1038/s41598-017-16869-2.

10.

A dietary flavone confers communicable protection against colitis through NLRP6 signaling independently of inflammasome activation.

Radulovic K, Normand S, Rehman A, Delanoye-Crespin A, Chatagnon J, Delacre M, Waldschmitt N, Poulin LF, Iovanna J, Ryffel B, Rosenstiel P, Chamaillard M.

Mucosal Immunol. 2018 May;11(3):811-819. doi: 10.1038/mi.2017.87. Epub 2017 Nov 15.

PMID:
29139477
11.

Keeping the (S)toolbox Alive Outside of the Body for Drugs Discovery.

Poulin LF, Peyrin-Biroulet L, Collard D, Chamaillard M.

Gastroenterology. 2017 Dec;153(6):1689-1691. doi: 10.1053/j.gastro.2017.10.022. Epub 2017 Oct 31. No abstract available.

PMID:
29100849
12.

Card9 mediates susceptibility to intestinal pathogens through microbiota modulation and control of bacterial virulence.

Lamas B, Michel ML, Waldschmitt N, Pham HP, Zacharioudaki V, Dupraz L, Delacre M, Natividad JM, Costa GD, Planchais J, Sovran B, Bridonneau C, Six A, Langella P, Richard ML, Chamaillard M, Sokol H.

Gut. 2018 Oct;67(10):1836-1844. doi: 10.1136/gutjnl-2017-314195. Epub 2017 Aug 8.

PMID:
28790160
13.

Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice.

Yadav P, Ellinghaus D, Rémy G, Freitag-Wolf S, Cesaro A, Degenhardt F, Boucher G, Delacre M; International IBD Genetics Consortium, Peyrin-Biroulet L, Pichavant M, Rioux JD, Gosset P, Franke A, Schumm LP, Krawczak M, Chamaillard M, Dempfle A, Andersen V.

Gastroenterology. 2017 Aug;153(2):550-565. doi: 10.1053/j.gastro.2017.05.010. Epub 2017 May 12.

14.

Microbiote intestinal : qu’en attendre au plan physiologique et thérapeutique ?

Doré J, Multon MC, Béhier JM; les participants à la table ronde 2 des Ateliers de Giens XXXII, Affagard H, Andremont A, Barthélémy P, Batista R, Bonneville M, Bonny C, Boyaval G, Chamaillard M, Chevalier MP, Cordaillat-Simmons M, Cournarie F, Diaz I, Guillaume E, Guyard C, Jouvin-Marche E, Martin FP, Petiteau D.

Therapie. 2017 Feb;72(1):1-19. doi: 10.1016/j.therap.2017.01.001. Epub 2017 Jan 11. French. No abstract available.

PMID:
28214070
15.

Enhancing the clinical coverage and anticancer efficacy of immune checkpoint blockade through manipulation of the gut microbiota.

Pitt JM, Vétizou M, Gomperts Boneca I, Lepage P, Chamaillard M, Zitvogel L.

Oncoimmunology. 2016 Feb 18;6(1):e1132137. doi: 10.1080/2162402X.2015.1132137. eCollection 2017.

16.

Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects.

Daillère R, Vétizou M, Waldschmitt N, Yamazaki T, Isnard C, Poirier-Colame V, Duong CPM, Flament C, Lepage P, Roberti MP, Routy B, Jacquelot N, Apetoh L, Becharef S, Rusakiewicz S, Langella P, Sokol H, Kroemer G, Enot D, Roux A, Eggermont A, Tartour E, Johannes L, Woerther PL, Chachaty E, Soria JC, Golden E, Formenti S, Plebanski M, Madondo M, Rosenstiel P, Raoult D, Cattoir V, Boneca IG, Chamaillard M, Zitvogel L.

Immunity. 2016 Oct 18;45(4):931-943. doi: 10.1016/j.immuni.2016.09.009. Epub 2016 Oct 4.

17.

The battlefield in the war against attaching-and-effacing bacterial pathogens: Monocytes, macrophages and dendritic cells in action.

Poulin LF, Chamaillard M.

Vet Microbiol. 2017 Apr;202:47-51. doi: 10.1016/j.vetmic.2016.09.007. Epub 2016 Sep 20. Review.

PMID:
27671967
18.

Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation.

Aden K, Rehman A, Falk-Paulsen M, Secher T, Kuiper J, Tran F, Pfeuffer S, Sheibani-Tezerji R, Breuer A, Luzius A, Jentzsch M, Häsler R, Billmann-Born S, Will O, Lipinski S, Bharti R, Adolph T, Iovanna JL, Kempster SL, Blumberg RS, Schreiber S, Becher B, Chamaillard M, Kaser A, Rosenstiel P.

Cell Rep. 2016 Aug 23;16(8):2208-2218. doi: 10.1016/j.celrep.2016.07.054. Epub 2016 Aug 11.

19.

Fine-Tuning Cancer Immunotherapy: Optimizing the Gut Microbiome.

Pitt JM, Vétizou M, Waldschmitt N, Kroemer G, Chamaillard M, Boneca IG, Zitvogel L.

Cancer Res. 2016 Aug 15;76(16):4602-7. doi: 10.1158/0008-5472.CAN-16-0448. Epub 2016 Jul 29. Review.

20.

STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection.

Queval CJ, Song OR, Deboosère N, Delorme V, Debrie AS, Iantomasi R, Veyron-Churlet R, Jouny S, Redhage K, Deloison G, Baulard A, Chamaillard M, Locht C, Brodin P.

Sci Rep. 2016 Jul 7;6:29297. doi: 10.1038/srep29297.

21.

Hemidesmosome integrity protects the colon against colitis and colorectal cancer.

De Arcangelis A, Hamade H, Alpy F, Normand S, Bruyère E, Lefebvre O, Méchine-Neuville A, Siebert S, Pfister V, Lepage P, Laquerriere P, Dembele D, Delanoye-Crespin A, Rodius S, Robine S, Kedinger M, Van Seuningen I, Simon-Assmann P, Chamaillard M, Labouesse M, Georges-Labouesse E.

Gut. 2017 Oct;66(10):1748-1760. doi: 10.1136/gutjnl-2015-310847. Epub 2016 Jul 1.

22.

Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors.

Pitt JM, Vétizou M, Daillère R, Roberti MP, Yamazaki T, Routy B, Lepage P, Boneca IG, Chamaillard M, Kroemer G, Zitvogel L.

Immunity. 2016 Jun 21;44(6):1255-69. doi: 10.1016/j.immuni.2016.06.001. Review.

23.

LppM impact on the colonization of macrophages by Mycobacterium tuberculosis.

Deboosère N, Iantomasi R, Queval CJ, Song OR, Deloison G, Jouny S, Debrie AS, Chamaillard M, Nigou J, Cohen-Gonsaud M, Locht C, Brodin P, Veyron-Churlet R.

Cell Microbiol. 2017 Jan;19(1). doi: 10.1111/cmi.12619. Epub 2016 Jul 11.

24.

Nod2-mediated recognition of the microbiota is critical for mucosal adjuvant activity of cholera toxin.

Kim D, Kim YG, Seo SU, Kim DJ, Kamada N, Prescott D, Chamaillard M, Philpott DJ, Rosenstiel P, Inohara N, Núñez G.

Nat Med. 2016 May;22(5):524-30. doi: 10.1038/nm.4075. Epub 2016 Apr 11. Erratum in: Nat Med. 2016 Aug 4;22(8):961.

25.

NOD2 gene variant is a risk factor for postoperative complications in patients with Crohn's disease: A genetic association study.

Germain A, Guéant RM, Chamaillard M, Allen PB, Bresler L, Guéant JL, Peyrin-Biroulet L.

Surgery. 2016 Jul;160(1):74-80. doi: 10.1016/j.surg.2016.01.013. Epub 2016 Mar 2.

PMID:
26946932
26.

Effects of enteral polymeric diet on gut microbiota in children with Crohn's disease.

Guinet-Charpentier C, Lepage P, Morali A, Chamaillard M, Peyrin-Biroulet L.

Gut. 2017 Jan;66(1):194-195. doi: 10.1136/gutjnl-2015-311058. Epub 2016 Jan 27. No abstract available.

PMID:
26818618
27.

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota.

Vétizou M, Pitt JM, Daillère R, Lepage P, Waldschmitt N, Flament C, Rusakiewicz S, Routy B, Roberti MP, Duong CP, Poirier-Colame V, Roux A, Becharef S, Formenti S, Golden E, Cording S, Eberl G, Schlitzer A, Ginhoux F, Mani S, Yamazaki T, Jacquelot N, Enot DP, Bérard M, Nigou J, Opolon P, Eggermont A, Woerther PL, Chachaty E, Chaput N, Robert C, Mateus C, Kroemer G, Raoult D, Boneca IG, Carbonnel F, Chamaillard M, Zitvogel L.

Science. 2015 Nov 27;350(6264):1079-84. doi: 10.1126/science.aad1329. Epub 2015 Nov 5.

28.

CARD8 gene variant is a risk factor for recurrent surgery in patients with Crohn's disease.

Germain A, Guéant RM, Chamaillard M, Bresler L, Guéant JL, Peyrin-Biroulet L.

Dig Liver Dis. 2015 Nov;47(11):938-42. doi: 10.1016/j.dld.2015.07.013. Epub 2015 Jul 29.

PMID:
26283210
29.

Defining dysbiosis threatens Koch's postulates and current dogma on the role of Paneth cells in Crohn's disease.

Chamaillard M, Radulovic K.

Gut. 2016 Feb;65(2):190-1. doi: 10.1136/gutjnl-2015-309714. Epub 2015 Aug 12. No abstract available.

PMID:
26268744
30.

Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth.

Lévy J, Cacheux W, Bara MA, L'Hermitte A, Lepage P, Fraudeau M, Trentesaux C, Lemarchand J, Durand A, Crain AM, Marchiol C, Renault G, Dumont F, Letourneur F, Delacre M, Schmitt A, Terris B, Perret C, Chamaillard M, Couty JP, Romagnolo B.

Nat Cell Biol. 2015 Aug;17(8):1062-73. doi: 10.1038/ncb3206. Epub 2015 Jul 27.

PMID:
26214133
31.

Photodynamic therapy as a new treatment modality for inflammatory and infectious conditions.

Reinhard A, Sandborn WJ, Melhem H, Bolotine L, Chamaillard M, Peyrin-Biroulet L.

Expert Rev Clin Immunol. 2015 May;11(5):637-57. doi: 10.1586/1744666X.2015.1032256. Epub 2015 Apr 3. Review.

PMID:
25837708
32.

Photodynamic therapy relieves colitis and prevents colitis-associated carcinogenesis in mice.

Reinhard A, Bressenot A, Dassonneville R, Loywick A, Hot D, Audebert C, Marchal S, Guillemin F, Chamaillard M, Peyrin-Biroulet L, Bezdetnaya L.

Inflamm Bowel Dis. 2015 May;21(5):985-95. doi: 10.1097/MIB.0000000000000354.

PMID:
25806846
33.

Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation.

Madouri F, Guillou N, Fauconnier L, Marchiol T, Rouxel N, Chenuet P, Ledru A, Apetoh L, Ghiringhelli F, Chamaillard M, Zheng SG, Trovero F, Quesniaux VF, Ryffel B, Togbe D.

J Mol Cell Biol. 2015 Aug;7(4):351-65. doi: 10.1093/jmcb/mjv012. Epub 2015 Feb 24.

PMID:
25714839
34.

Time for epithelial sensing of vitamin D to step into the limelight.

Waldschmitt N, Chamaillard M.

Gut. 2015 Jul;64(7):1013-4. doi: 10.1136/gutjnl-2014-308119. Epub 2014 Dec 5. No abstract available.

PMID:
25480311
35.

Gut microbiome and anticancer immune response: really hot Sh*t!

Viaud S, Daillère R, Boneca IG, Lepage P, Langella P, Chamaillard M, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L.

Cell Death Differ. 2015 Feb;22(2):199-214. doi: 10.1038/cdd.2014.56. Epub 2014 May 16. Review.

36.

CCL17 production by dendritic cells is required for NOD1-mediated exacerbation of allergic asthma.

Ait Yahia S, Azzaoui I, Everaere L, Vorng H, Chenivesse C, Marquillies P, Duez C, Delacre M, Grandjean T, Balsamelli J, Fanton d'Andon M, Fan Y, Ple C, Werts C, Boneca IG, Wallaert B, Chamaillard M, Tsicopoulos A.

Am J Respir Crit Care Med. 2014 Apr 15;189(8):899-908. doi: 10.1164/rccm.201310-1827OC.

PMID:
24661094
37.

Colonic expression of the peptide transporter PEPT1 is downregulated during intestinal inflammation and is not required for NOD2-dependent immune activation.

Wuensch T, Ullrich S, Schulz S, Chamaillard M, Schaltenberg N, Rath E, Goebel U, Sartor RB, Prager M, Büning C, Bugert P, Witt H, Haller D, Daniel H.

Inflamm Bowel Dis. 2014 Apr;20(4):671-84. doi: 10.1097/01.MIB.0000443336.71488.08.

PMID:
24583477
38.

Toll-interacting protein modulates colitis susceptibility in mice.

Maillard MH, Bega H, Uhlig HH, Barnich N, Grandjean T, Chamaillard M, Michetti P, Velin D.

Inflamm Bowel Dis. 2014 Apr;20(4):660-70. doi: 10.1097/MIB.0000000000000006.

PMID:
24572204
39.

Pseudomonas aeruginosa type-3 secretion system dampens host defense by exploiting the NLRC4-coupled inflammasome.

Faure E, Mear JB, Faure K, Normand S, Couturier-Maillard A, Grandjean T, Balloy V, Ryffel B, Dessein R, Chignard M, Uyttenhove C, Guery B, Gosset P, Chamaillard M, Kipnis E.

Am J Respir Crit Care Med. 2014 Apr 1;189(7):799-811. doi: 10.1164/rccm.201307-1358OC.

PMID:
24555512
40.

Pancreatitis-associated protein does not predict disease relapse in inflammatory bowel disease patients.

Nunes T, Etchevers MJ, Sandi MJ, Pinó Donnay S, Grandjean T, Pellisé M, Panés J, Ricart E, Iovanna JL, Dagorn JC, Chamaillard M, Sans M.

PLoS One. 2014 Jan 9;9(1):e84957. doi: 10.1371/journal.pone.0084957. eCollection 2014.

41.

Decoding norovirus infection in Crohn's disease.

Chamaillard M, Cesaro A, Lober PE, Hober D.

Inflamm Bowel Dis. 2014 Apr;20(4):767-70. doi: 10.1097/01.MIB.0000440613.83703.4a. Review.

PMID:
24351661
42.

Phagocytes migration in response to an emergency call from the microbiota.

Chauvin C, Peyrin-Biroulet L, Chamaillard M, Poulin LF.

Gastroenterology. 2013 Nov;145(5):1150-1. doi: 10.1053/j.gastro.2013.09.017. Epub 2013 Sep 19. No abstract available.

PMID:
24055636
43.

Functional polymorphisms in the regulatory regions of the VNN1 gene are associated with susceptibility to inflammatory bowel diseases.

Gensollen T, Bourges C, Rihet P, Rostan A, Millet V, Noguchi T, Bourdon V, Sobol H, Dubuquoy L, Bertin B, Fumery M, Desreumaux P, Colombel JF, Chamaillard M, Hebuterne X, Hofman P, Naquet P, Galland F.

Inflamm Bowel Dis. 2013 Oct;19(11):2315-25. doi: 10.1097/MIB.0b013e3182a32b03. Erratum in: Inflamm Bowel Dis. 2014 Aug;20(8):1457. Chamaillard, Mathias [added].

PMID:
23949622
44.

[Dysbiosis, a new medical concept].

Normand S, Secher T, Chamaillard M.

Med Sci (Paris). 2013 Jun-Jul;29(6-7):586-9. doi: 10.1051/medsci/2013296011. Epub 2013 Jul 12. French. No abstract available.

45.

NOD2 prevents emergence of disease-predisposing microbiota.

Secher T, Normand S, Chamaillard M.

Gut Microbes. 2013 Jul-Aug;4(4):353-6. doi: 10.4161/gmic.25275. Epub 2013 Jun 6.

46.

The peptide transporter PEPT1 is expressed in distal colon in rodents and humans and contributes to water absorption.

Wuensch T, Schulz S, Ullrich S, Lill N, Stelzl T, Rubio-Aliaga I, Loh G, Chamaillard M, Haller D, Daniel H.

Am J Physiol Gastrointest Liver Physiol. 2013 Jul 1;305(1):G66-73. doi: 10.1152/ajpgi.00491.2012. Epub 2013 May 9.

47.

Enterocyte loss of polarity and gut wound healing rely upon the F-actin-severing function of villin.

Ubelmann F, Chamaillard M, El-Marjou F, Simon A, Netter J, Vignjevic D, Nichols BL, Quezada-Calvillo R, Grandjean T, Louvard D, Revenu C, Robine S.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):E1380-9. doi: 10.1073/pnas.1218446110. Epub 2013 Mar 21.

48.

NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer.

Couturier-Maillard A, Secher T, Rehman A, Normand S, De Arcangelis A, Haesler R, Huot L, Grandjean T, Bressenot A, Delanoye-Crespin A, Gaillot O, Schreiber S, Lemoine Y, Ryffel B, Hot D, Nùñez G, Chen G, Rosenstiel P, Chamaillard M.

J Clin Invest. 2013 Feb;123(2):700-11. doi: 10.1172/JCI62236. Epub 2013 Jan 2.

49.

Looking beyond histological healing in ulcerative colitis: towards the establishment of a molecular signature for quiescent but progressive disease.

Chamaillard M, Chevaux JB, Peyrin-Biroulet L.

Gut. 2013 Jul;62(7):959-60. doi: 10.1136/gutjnl-2012-303765. Epub 2012 Dec 13. No abstract available.

PMID:
23242120
50.

Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice.

Sedhom MA, Pichery M, Murdoch JR, Foligné B, Ortega N, Normand S, Mertz K, Sanmugalingam D, Brault L, Grandjean T, Lefrancais E, Fallon PG, Quesniaux V, Peyrin-Biroulet L, Cathomas G, Junt T, Chamaillard M, Girard JP, Ryffel B.

Gut. 2013 Dec;62(12):1714-23. doi: 10.1136/gutjnl-2011-301785. Epub 2012 Nov 21.

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