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Items: 35

1.

Disrupting Gram-Negative Bacterial Outer Membrane Biosynthesis through Inhibition of the Lipopolysaccharide Transporter MsbA.

Alexander MK, Miu A, Oh A, Reichelt M, Ho H, Chalouni C, Labadie S, Wang L, Liang J, Nickerson NN, Hu H, Yu L, Du M, Yan D, Park S, Kim J, Xu M, Sellers BD, Purkey HE, Skelton NJ, Koehler MFT, Payandeh J, Verma V, Xu Y, Koth CM, Nishiyama M.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01142-18. doi: 10.1128/AAC.01142-18. Print 2018 Nov.

PMID:
30104274
2.

An Anti-CLL-1 Antibody-Drug Conjugate for the Treatment of Acute Myeloid Leukemia.

Zheng B, Yu SF, Del Rosario G, Leong SR, Lee GY, Vij R, Chiu C, Liang WC, Wu Y, Chalouni C, Sadowsky J, Clark V, Hendricks A, Poon KA, Chu W, Pillow T, Schutten MM, Flygare J, Polson AG.

Clin Cancer Res. 2018 Jun 29. doi: 10.1158/1078-0432.CCR-18-0333. [Epub ahead of print]

PMID:
29959143
3.

FRET Reagent Reveals the Intracellular Processing of Peptide-Linked Antibody-Drug Conjugates.

Lee BC, Chalouni C, Doll S, Nalle SC, Darwish M, Tsai SP, Kozak KR, Del-Rosario G, Yu SF, Erickson H, Vandlen R.

Bioconjug Chem. 2018 Jul 18;29(7):2468-2477. doi: 10.1021/acs.bioconjchem.8b00362. Epub 2018 Jun 13.

PMID:
29856915
4.

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.

Mariathasan S, Turley SJ, Nickles D, Castiglioni A, Yuen K, Wang Y, Kadel EE III, Koeppen H, Astarita JL, Cubas R, Jhunjhunwala S, Banchereau R, Yang Y, Guan Y, Chalouni C, Ziai J, Şenbabaoğlu Y, Santoro S, Sheinson D, Hung J, Giltnane JM, Pierce AA, Mesh K, Lianoglou S, Riegler J, Carano RAD, Eriksson P, Höglund M, Somarriba L, Halligan DL, van der Heijden MS, Loriot Y, Rosenberg JE, Fong L, Mellman I, Chen DS, Green M, Derleth C, Fine GD, Hegde PS, Bourgon R, Powles T.

Nature. 2018 Feb 22;554(7693):544-548. doi: 10.1038/nature25501. Epub 2018 Feb 14.

5.

Fate of Antibody-Drug Conjugates in Cancer Cells.

Chalouni C, Doll S.

J Exp Clin Cancer Res. 2018 Feb 6;37(1):20. doi: 10.1186/s13046-017-0667-1. Review.

6.

Visualization of early influenza A virus trafficking in human dendritic cells using STED microscopy.

Baharom F, Thomas OS, Lepzien R, Mellman I, Chalouni C, Smed-Sörensen A.

PLoS One. 2017 Jun 7;12(6):e0177920. doi: 10.1371/journal.pone.0177920. eCollection 2017.

7.

Cellular uptake of a cystine-knot peptide and modulation of its intracellular trafficking.

Gao X, Stanger K, Kaluarachchi H, Maurer T, Ciepla P, Chalouni C, Franke Y, Hannoush RN.

Sci Rep. 2016 Oct 13;6:35179. doi: 10.1038/srep35179.

8.

Novel antibody-antibiotic conjugate eliminates intracellular S. aureus.

Lehar SM, Pillow T, Xu M, Staben L, Kajihara KK, Vandlen R, DePalatis L, Raab H, Hazenbos WL, Morisaki JH, Kim J, Park S, Darwish M, Lee BC, Hernandez H, Loyet KM, Lupardus P, Fong R, Yan D, Chalouni C, Luis E, Khalfin Y, Plise E, Cheong J, Lyssikatos JP, Strandh M, Koefoed K, Andersen PS, Flygare JA, Wah Tan M, Brown EJ, Mariathasan S.

Nature. 2015 Nov 19;527(7578):323-8. doi: 10.1038/nature16057. Epub 2015 Nov 4.

PMID:
26536114
9.

An anti-B7-H4 antibody-drug conjugate for the treatment of breast cancer.

Leong SR, Liang WC, Wu Y, Crocker L, Cheng E, Sampath D, Ohri R, Raab H, Hass PE, Pham T, Firestein R, Li D, Schutten M, Stagg NJ, Ogasawara A, Koppada N, Roth L, Williams SP, Lee BC, Chalouni C, Peng I, DeVoss J, Tremayne J, Polakis P, Polson AG.

Mol Pharm. 2015 Jun 1;12(6):1717-29. doi: 10.1021/mp5007745. Epub 2015 Apr 23.

PMID:
25853436
10.

Afucosylated antibodies increase activation of FcγRIIIa-dependent signaling components to intensify processes promoting ADCC.

Liu SD, Chalouni C, Young JC, Junttila TT, Sliwkowski MX, Lowe JB.

Cancer Immunol Res. 2015 Feb;3(2):173-83. doi: 10.1158/2326-6066.CIR-14-0125. Epub 2014 Nov 11.

11.

Imaging cleared intact biological systems at a cellular level by 3DISCO.

Ertürk A, Lafkas D, Chalouni C.

J Vis Exp. 2014 Jul 7;(89). doi: 10.3791/51382.

12.

Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains.

Bainbridge TW, DeAlmeida VI, Izrael-Tomasevic A, Chalouni C, Pan B, Goldsmith J, Schoen AP, Quiñones GA, Kelly R, Lill JR, Sandoval W, Costa M, Polakis P, Arnott D, Rubinfeld B, Ernst JA.

PLoS One. 2014 Jul 16;9(7):e102695. doi: 10.1371/journal.pone.0102695. eCollection 2014.

13.

Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation.

Vander Lugt B, Khan AA, Hackney JA, Agrawal S, Lesch J, Zhou M, Lee WP, Park S, Xu M, DeVoss J, Spooner CJ, Chalouni C, Delamarre L, Mellman I, Singh H.

Nat Immunol. 2014 Feb;15(2):161-7. doi: 10.1038/ni.2795. Epub 2013 Dec 22.

PMID:
24362890
14.

Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling.

Wilson CW, Parker LH, Hall CJ, Smyczek T, Mak J, Crow A, Posthuma G, De Mazière A, Sagolla M, Chalouni C, Vitorino P, Roose-Girma M, Warming S, Klumperman J, Crosier PS, Ye W.

Blood. 2013 Nov 21;122(22):3678-90. doi: 10.1182/blood-2013-02-483156. Epub 2013 Jul 25.

15.

Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation.

Cohn L, Chatterjee B, Esselborn F, Smed-Sörensen A, Nakamura N, Chalouni C, Lee BC, Vandlen R, Keler T, Lauer P, Brockstedt D, Mellman I, Delamarre L.

J Exp Med. 2013 May 6;210(5):1049-63. doi: 10.1084/jem.20121251. Epub 2013 Apr 8.

16.

Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells.

Chatterjee B, Smed-Sörensen A, Cohn L, Chalouni C, Vandlen R, Lee BC, Widger J, Keler T, Delamarre L, Mellman I.

Blood. 2012 Sep 6;120(10):2011-20. doi: 10.1182/blood-2012-01-402370. Epub 2012 Jul 12.

17.

The melanosomal protein PMEL17 as a target for antibody drug conjugate therapy in melanoma.

Chen Y, Chalouni C, Tan C, Clark R, Venook R, Ohri R, Raab H, Firestein R, Mallet W, Polakis P.

J Biol Chem. 2012 Jul 13;287(29):24082-91. doi: 10.1074/jbc.M112.361485. Epub 2012 May 21.

18.

Influenza A virus infection of human primary dendritic cells impairs their ability to cross-present antigen to CD8 T cells.

Smed-Sörensen A, Chalouni C, Chatterjee B, Cohn L, Blattmann P, Nakamura N, Delamarre L, Mellman I.

PLoS Pathog. 2012;8(3):e1002572. doi: 10.1371/journal.ppat.1002572. Epub 2012 Mar 8.

19.

A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain.

Chih B, Liu P, Chinn Y, Chalouni C, Komuves LG, Hass PE, Sandoval W, Peterson AS.

Nat Cell Biol. 2011 Dec 18;14(1):61-72. doi: 10.1038/ncb2410.

PMID:
22179047
20.

Equilibrative nucleoside transporter 3 deficiency perturbs lysosome function and macrophage homeostasis.

Hsu CL, Lin W, Seshasayee D, Chen YH, Ding X, Lin Z, Suto E, Huang Z, Lee WP, Park H, Xu M, Sun M, Rangell L, Lutman JL, Ulufatu S, Stefanich E, Chalouni C, Sagolla M, Diehl L, Fielder P, Dean B, Balazs M, Martin F.

Science. 2012 Jan 6;335(6064):89-92. doi: 10.1126/science.1213682. Epub 2011 Dec 15.

21.

Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome.

Westlake CJ, Baye LM, Nachury MV, Wright KJ, Ervin KE, Phu L, Chalouni C, Beck JS, Kirkpatrick DS, Slusarski DC, Sheffield VC, Scheller RH, Jackson PK.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2759-64. doi: 10.1073/pnas.1018823108. Epub 2011 Jan 27.

22.

Mature dendritic cells use endocytic receptors to capture and present antigens.

Platt CD, Ma JK, Chalouni C, Ebersold M, Bou-Reslan H, Carano RA, Mellman I, Delamarre L.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4287-92. doi: 10.1073/pnas.0910609107. Epub 2010 Feb 8.

23.

Chitin is a size-dependent regulator of macrophage TNF and IL-10 production.

Da Silva CA, Chalouni C, Williams A, Hartl D, Lee CG, Elias JA.

J Immunol. 2009 Mar 15;182(6):3573-82. doi: 10.4049/jimmunol.0802113.

24.

Replacement of bone marrow by bone in rat femurs: the bone bioreactor.

Zhang Q, Cuartas E, Mehta N, Gilligan J, Ke HZ, Saltzman WM, Kotas M, Ma M, Rajan S, Chalouni C, Carlson J, Vignery A.

Tissue Eng Part A. 2008 Feb;14(2):237-46. doi: 10.1089/tea.2007.0261.

PMID:
18333776
25.

A33 antigen displays persistent surface expression.

Ackerman ME, Chalouni C, Schmidt MM, Raman VV, Ritter G, Old LJ, Mellman I, Wittrup KD.

Cancer Immunol Immunother. 2008 Jul;57(7):1017-27. doi: 10.1007/s00262-007-0433-x.

26.

Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function.

Bernatchez PN, Acevedo L, Fernandez-Hernando C, Murata T, Chalouni C, Kim J, Erdjument-Bromage H, Shah V, Gratton JP, McNally EM, Tempst P, Sessa WC.

J Biol Chem. 2007 Oct 19;282(42):30745-53. Epub 2007 Aug 16.

27.

Priming, initiation and synchronization of the segmentation clock by deltaD and deltaC.

Mara A, Schroeder J, Chalouni C, Holley SA.

Nat Cell Biol. 2007 May;9(5):523-30. Epub 2007 Apr 8.

PMID:
17417625
28.

Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking.

Iwakiri Y, Satoh A, Chatterjee S, Toomre DK, Chalouni CM, Fulton D, Groszmann RJ, Shah VH, Sessa WC.

Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19777-82. Epub 2006 Dec 14.

29.

The intracellular domain of CD44 promotes the fusion of macrophages.

Cui W, Ke JZ, Zhang Q, Ke HZ, Chalouni C, Vignery A.

Blood. 2006 Jan 15;107(2):796-805. Epub 2005 Sep 29.

30.

Unravelling the secrets of the crypts.

Chalouni C.

Nat Cell Biol. 2004 Nov;6(11):1069. No abstract available.

PMID:
15517001
31.

Golgi duplication in Trypanosoma brucei.

He CY, Ho HH, Malsam J, Chalouni C, West CM, Ullu E, Toomre D, Warren G.

J Cell Biol. 2004 May 10;165(3):313-21.

32.

Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6.

Jego G, Palucka AK, Blanck JP, Chalouni C, Pascual V, Banchereau J.

Immunity. 2003 Aug;19(2):225-34.

33.

Human germinal center B cells differ from naive and memory B cells by their aggregated MHC class II-rich compartments lacking HLA-DO.

Chalouni C, Banchereau J, Vogt AB, Pascual V, Davoust J.

Int Immunol. 2003 Apr;15(4):457-66.

PMID:
12663675
34.

Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells.

Mohamadzadeh M, Berard F, Essert G, Chalouni C, Pulendran B, Davoust J, Bridges G, Palucka AK, Banchereau J.

J Exp Med. 2001 Oct 1;194(7):1013-20.

35.

Flt3-ligand and granulocyte colony-stimulating factor mobilize distinct human dendritic cell subsets in vivo.

Pulendran B, Banchereau J, Burkeholder S, Kraus E, Guinet E, Chalouni C, Caron D, Maliszewski C, Davoust J, Fay J, Palucka K.

J Immunol. 2000 Jul 1;165(1):566-72.

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