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Items: 1 to 50 of 407

1.

Effects of the Informed Health Choices podcast on the ability of parents of primary school children in Uganda to assess the trustworthiness of claims about treatment effects: one-year follow up of a randomised trial.

Semakula D, Nsangi A, Oxman AD, Oxman M, Austvoll-Dahlgren A, Rosenbaum S, Morelli A, Glenton C, Lewin S, Nyirazinyoye L, Kaseje M, Chalmers I, Fretheim A, Rose CJ, Sewankambo NK.

Trials. 2020 Feb 14;21(1):187. doi: 10.1186/s13063-020-4093-x.

PMID:
32059694
2.

Claims of 'no difference' or 'no effect' in Cochrane and other systematic reviews.

Marson Smith PR, Ware L, Adams C, Chalmers I.

BMJ Evid Based Med. 2020 Jan 7. pii: bmjebm-2019-111257. doi: 10.1136/bmjebm-2019-111257. [Epub ahead of print]

3.

Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects, 1-year follow-up: a cluster-randomised trial.

Nsangi A, Semakula D, Oxman AD, Austvoll-Dahlgren A, Oxman M, Rosenbaum S, Morelli A, Glenton C, Lewin S, Kaseje M, Chalmers I, Fretheim A, Ding Y, Sewankambo NK.

Trials. 2020 Jan 6;21(1):27. doi: 10.1186/s13063-019-3960-9.

4.

The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets.

Whatley KCL, Padalino G, Whiteland H, Geyer KK, Hulme BJ, Chalmers IW, Forde-Thomas J, Ferla S, Brancale A, Hoffmann KF.

PLoS Negl Trop Dis. 2019 Nov 15;13(11):e0007693. doi: 10.1371/journal.pntd.0007693. eCollection 2019 Nov.

5.

Personalised Medicine Using N-of-1 Trials: Overcoming Barriers to Delivery.

Chalmers I, Smeeth L, Goldacre B.

Healthcare (Basel). 2019 Nov 5;7(4). pii: E134. doi: 10.3390/healthcare7040134.

6.

Reducing research waste by promoting informed responses to invitations to participate in clinical trials.

Gillies K, Chalmers I, Glasziou P, Elbourne D, Elliott J, Treweek S.

Trials. 2019 Oct 28;20(1):613. doi: 10.1186/s13063-019-3704-x.

7.

Assisted dying: restricting access to people with fewer than six months to live is discriminatory.

Sleeman K, Chalmers I.

BMJ. 2019 Oct 21;367:l6093. doi: 10.1136/bmj.l6093. No abstract available.

PMID:
31636090
8.

US Food and Drug Administration Approvals of Drugs and Devices Based on Nonrandomized Clinical Trials: A Systematic Review and Meta-analysis.

Razavi M, Glasziou P, Klocksieben FA, Ioannidis JPA, Chalmers I, Djulbegovic B.

JAMA Netw Open. 2019 Sep 4;2(9):e1911111. doi: 10.1001/jamanetworkopen.2019.11111.

9.

John Henry Gaddum's 1940 guidance on controlled clinical trials.

Marson Smith P, Colquhoun D, Chalmers I.

J R Soc Med. 2019 Sep;112(9):394-400. doi: 10.1177/0141076819870674. No abstract available.

PMID:
31496349
10.

The importance of randomised vs non-randomised trials.

Djulbegovic B, Glasziou P, Chalmers I.

Lancet. 2019 Aug 24;394(10199):634-635. doi: 10.1016/S0140-6736(19)31128-6. No abstract available.

PMID:
31448731
11.

Key concepts for making informed choices.

Aronson JK, Barends E, Boruch R, Brennan M, Chalmers I, Chislett J, Cunliffe-Jones P, Dahlgren A, Gaarder M, Haines A, Heneghan C, Matthews R, Maynard B, Oxman AD, Oxman M, Pullin A, Randall N, Roddam H, Schoonees A, Sharples J, Stewart R, Stott J, Tallis R, Thomas N, Vale L.

Nature. 2019 Aug;572(7769):303-306. doi: 10.1038/d41586-019-02407-9. No abstract available.

PMID:
31406318
12.

Erratum to 'Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni' [IJP Drugs Drug Resist. 8 (2018) 559-570].

Padalino G, Ferla S, Brancale A, Chalmers IW, Hoffmann KF.

Int J Parasitol Drugs Drug Resist. 2019 Aug;10:91. doi: 10.1016/j.ijpddr.2019.07.001. Epub 2019 Jul 2. No abstract available.

13.

Promoting critical appraisal skills.

Elessi K, Albarqouni L, Glasziou P, Chalmers I.

Lancet. 2019 Jun 29;393(10191):2589-2590. doi: 10.1016/S0140-6736(19)30346-0. Epub 2019 Jun 27. No abstract available.

PMID:
31258125
14.

Schistosoma mansoni venom allergen-like proteins: phylogenetic relationships, stage-specific transcription and tissue localization as predictors of immunological cross-reactivity.

Farias LP, Chalmers IW, Perally S, Rofatto HK, Jackson CJ, Brown M, Khouri MI, Barbosa MMF, Hensbergen PJ, Hokke CH, Leite LCC, Hoffmann KF.

Int J Parasitol. 2019 Jul;49(8):593-599. doi: 10.1016/j.ijpara.2019.03.003. Epub 2019 May 25.

15.

Authors' reply to Sharp and Curlewis, Ahmed and colleagues, and Sreeharan.

Glasziou P, Chalmers I.

BMJ. 2019 Mar 8;364:l808. doi: 10.1136/bmj.l808. No abstract available.

PMID:
30850382
16.

Helping physicians to keep abreast of the medical literature: Andrew Duncan and Medical and Philosophical Commentaries, 1773-1795.

Chalmers J, Chalmers I, Troehler U.

J R Soc Med. 2019 Jan;112(1):36-47. doi: 10.1177/0141076818820779. No abstract available.

PMID:
30798721
17.

The James Lind Initiative: books, websites and databases to promote critical thinking about treatment claims, 2003 to 2018.

Chalmers I, Atkinson P, Badenoch D, Glasziou P, Austvoll-Dahlgren A, Oxman A, Clarke M.

Res Involv Engagem. 2019 Feb 4;5:6. doi: 10.1186/s40900-019-0138-2. eCollection 2019.

18.

Key Concepts for assessing claims about treatment effects and making well-informed treatment choices.

Oxman AD, Chalmers I, Austvoll-Dahlgren A; Informed Health Choices group.

Version 2. F1000Res. 2018 Nov 12 [revised 2019 Jan 1];7:1784. doi: 10.12688/f1000research.16771.2. eCollection 2018.

19.

Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni.

Padalino G, Ferla S, Brancale A, Chalmers IW, Hoffmann KF.

Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):559-570. doi: 10.1016/j.ijpddr.2018.10.005. Epub 2018 Nov 13. Erratum in: Int J Parasitol Drugs Drug Resist. 2019 Aug;10:91.

20.

Antibody responses to Schistosoma mansoni schistosomula antigens.

Egesa M, Lubyayi L, Jones FM, van Diepen A, Chalmers IW, Tukahebwa EM, Bagaya BS, Hokke CH, Hoffmann KF, Dunne DW, Elliott AM, Yazdanbakhsh M, Wilson S, Cose S.

Parasite Immunol. 2018 Dec;40(12):e12591. doi: 10.1111/pim.12591. Epub 2018 Oct 14.

21.

Schistosoma mansoni schistosomula antigens induce Th1/Pro-inflammatory cytokine responses.

Egesa M, Lubyayi L, Tukahebwa EM, Bagaya BS, Chalmers IW, Wilson S, Hokke CH, Hoffmann KF, Dunne DW, Yazdanbakhsh M, Labuda LA, Cose S.

Parasite Immunol. 2018 Dec;40(12):e12592. doi: 10.1111/pim.12592. Epub 2018 Oct 21.

22.

Switching From Originator to Biosimilar Infliximab in Paediatric Inflammatory Bowel Disease Is Feasible and Uneventful.

Gervais L, McLean LL, Wilson ML, Cameron C, Curtis L, Garrick V, Armstrong K, Tayler R, Henderson P, Hansen R, Chalmers I, Wilson DC, Russell RK.

J Pediatr Gastroenterol Nutr. 2018 Dec;67(6):745-748. doi: 10.1097/MPG.0000000000002091.

PMID:
29985877
23.

Reflections on the history of systematic reviews.

Clarke M, Chalmers I.

BMJ Evid Based Med. 2018 Aug;23(4):121-122. doi: 10.1136/bmjebm-2018-110968. Epub 2018 Jun 19. No abstract available.

PMID:
29921711
24.

'Allocation concealment': the evolution and adoption of a methodological term.

Schulz KF, Chalmers I, Altman DG, Grimes DA, Moher D, Hayes RJ.

J R Soc Med. 2018 Jun;111(6):216-224. doi: 10.1177/0141076818776604. Review. No abstract available.

25.

Adrian Grant's pioneering use of evidence synthesis in perinatal medicine, 1980-1992.

Chalmers I.

Reprod Health. 2018 May 15;15(1):79. doi: 10.1186/s12978-018-0518-3.

26.

Educational interventions to improve people's understanding of key concepts in assessing the effects of health interventions: a systematic review.

Cusack L, Del Mar CB, Chalmers I, Gibson E, Hoffmann TC.

Syst Rev. 2018 May 2;7(1):68. doi: 10.1186/s13643-018-0719-4.

27.

Deaths of children and women in Gaza hostilities.

Chalmers I.

Lancet. 2018 Feb 10;391(10120):539-540. doi: 10.1016/S0140-6736(17)32179-7. No abstract available.

PMID:
29617244
28.

Larger effect sizes in nonrandomized studies are associated with higher rates of EMA licensing approval.

Djulbegovic B, Glasziou P, Klocksieben FA, Reljic T, VanDenBergh M, Mhaskar R, Ioannidis JPA, Chalmers I.

J Clin Epidemiol. 2018 Jun;98:24-32. doi: 10.1016/j.jclinepi.2018.01.011. Epub 2018 Feb 10. Review.

PMID:
29432860
29.

Key Concepts for Informed Health Choices: a framework for helping people learn how to assess treatment claims and make informed choices.

Chalmers I, Oxman AD, Austvoll-Dahlgren A, Ryan-Vig S, Pannell S, Sewankambo N, Semakula D, Nsangi A, Albarqouni L, Glasziou P, Mahtani K, Nunan D, Heneghan C, Badenoch D.

BMJ Evid Based Med. 2018 Feb;23(1):29-33. doi: 10.1136/ebmed-2017-110829.

PMID:
29367324
30.

Corrigendum: Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

Adema CM, Hillier LW, Jones CS, Loker ES, Knight M, Minx P, Oliveira G, Raghavan N, Shedlock A, do Amaral LR, Arican-Goktas HD, Assis JG, Baba EH, Baron OL, Bayne CJ, Bickham-Wright U, Biggar KK, Blouin M, Bonning BC, Botka C, Bridger JM, Buckley KM, Buddenborg SK, Lima Caldeira R, Carleton J, Carvalho OS, Castillo MG, Chalmers IW, Christensens M, Clifton S, Cosseau C, Coustau C, Cripps RM, Cuesta-Astroz Y, Cummins SF, Di Stefano L, Dinguirard N, Duval D, Emrich S, Feschotte C, Feyereisen R, FitzGerald P, Fronick C, Fulton L, Galinier R, Gava SG, Geusz M, Geyer KK, Giraldo-Calderón GI, de Souza Gomes M, Gordy MA, Gourbal B, Grunau C, Hanington PC, Hoffmann KF, Hughes D, Humphries J, Jackson DJ, Jannotti-Passos LK, de Jesus Jeremias W, Jobling S, Kamel B, Kapusta A, Kaur S, Koene JM, Kohn AB, Lawson D, Lawton SP, Liang D, Limpanont Y, Liu S, Lockyer AE, Lovato TAL, Ludolf F, Magrini V, McManus DP, Medina M, Misra M, Mitta G, Mkoji GM, Montague MJ, Montelongo C, Moroz LL, Munoz-Torres MC, Niazi U, Noble LR, Oliveira FS, Pais FS, Papenfuss AT, Peace R, Pena JJ, Pila EA, Quelais T, Raney BJ, Rast JP, Rollinson D, Rosse IC, Rotgans B, Routledge EJ, Ryan KM, Scholte LLS, Storey KB, Swain M, Tennessen JA, Tomlinson C, Trujillo DL, Volpi EV, Walker AJ, Wang T, Wannaporn I, Warren WC, Wu XJ, Yoshino TP, Yusuf M, Zhang SM, Zhao M, Wilson RK.

Nat Commun. 2017 Aug 23;8:16153. doi: 10.1038/ncomms16153.

31.

Establishing a library of resources to help people understand key concepts in assessing treatment claims-The "Critical thinking and Appraisal Resource Library" (CARL).

Castle JC, Chalmers I, Atkinson P, Badenoch D, Oxman AD, Austvoll-Dahlgren A, Nordheim L, Krause LK, Schwartz LM, Woloshin S, Burls A, Mosconi P, Hoffmann T, Cusack L, Albarqouni L, Glasziou P.

PLoS One. 2017 Jul 24;12(7):e0178666. doi: 10.1371/journal.pone.0178666. eCollection 2017.

32.

Choosing treatments when the effect of alternatives is uncertain.

Chalmers I.

BMJ. 2017 Jul 20;358:j3530. doi: 10.1136/bmj.j3530. No abstract available.

PMID:
28729283
33.

Caleb Parry and 18th century controlled comparisons of Turkish and English rhubarb

Chalmers I.

J R Coll Physicians Edinb. 2017 Jun;47(2):205. doi: 10.4997/JRCPE.2017.222. No abstract available.

PMID:
28682041
34.

Focus on sharing individual patient data distracts from other ways of improving trial transparency.

Hoffmann T, Glasziou P, Beller E, Goldacre B, Chalmers I.

BMJ. 2017 Jun 22;357:j2782. doi: 10.1136/bmj.j2782. Review. No abstract available.

PMID:
28642275
35.

The quality of reports of medical and public health research from Palestinian institutions: a systematic review.

Albarqouni L, Abu-Rmeileh NM, Elessi K, Obeidallah M, Bjertness E, Chalmers I.

BMJ Open. 2017 Jun 9;7(6):e016455. doi: 10.1136/bmjopen-2017-016455. Review.

36.

Effects of the Informed Health Choices podcast on the ability of parents of primary school children in Uganda to assess claims about treatment effects: a randomised controlled trial.

Semakula D, Nsangi A, Oxman AD, Oxman M, Austvoll-Dahlgren A, Rosenbaum S, Morelli A, Glenton C, Lewin S, Kaseje M, Chalmers I, Fretheim A, Kristoffersen DT, Sewankambo NK.

Lancet. 2017 Jul 22;390(10092):389-398. doi: 10.1016/S0140-6736(17)31225-4. Epub 2017 May 22.

PMID:
28539196
37.

Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects: a cluster-randomised controlled trial.

Nsangi A, Semakula D, Oxman AD, Austvoll-Dahlgren A, Oxman M, Rosenbaum S, Morelli A, Glenton C, Lewin S, Kaseje M, Chalmers I, Fretheim A, Ding Y, Sewankambo NK.

Lancet. 2017 Jul 22;390(10092):374-388. doi: 10.1016/S0140-6736(17)31226-6. Epub 2017 May 22.

PMID:
28539194
38.

Does the use of the Informed Healthcare Choices (IHC) primary school resources improve the ability of grade-5 children in Uganda to assess the trustworthiness of claims about the effects of treatments: protocol for a cluster-randomised trial.

Nsangi A, Semakula D, Oxman AD, Oxman M, Rosenbaum S, Austvoll-Dahlgren A, Nyirazinyoye L, Kaseje M, Chalmers I, Fretheim A, Sewankambo NK.

Trials. 2017 May 18;18(1):223. doi: 10.1186/s13063-017-1958-8.

39.

Measuring ability to assess claims about treatment effects: the development of the 'Claim Evaluation Tools'.

Austvoll-Dahlgren A, Semakula D, Nsangi A, Oxman AD, Chalmers I, Rosenbaum S, Guttersrud Ø; IHC Group.

BMJ Open. 2017 May 17;7(5):e013184. doi: 10.1136/bmjopen-2016-013184.

40.

Critical thinking in healthcare and education.

Sharples JM, Oxman AD, Mahtani KR, Chalmers I, Oliver S, Collins K, Austvoll-Dahlgren A, Hoffmann T.

BMJ. 2017 May 16;357:j2234. doi: 10.1136/bmj.j2234. No abstract available.

PMID:
28512135
41.

The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni.

Geyer KK, Niazi UH, Duval D, Cosseau C, Tomlinson C, Chalmers IW, Swain MT, Cutress DJ, Bickham-Wright U, Munshi SE, Grunau C, Yoshino TP, Hoffmann KF.

PLoS Negl Trop Dis. 2017 May 16;11(5):e0005246. doi: 10.1371/journal.pntd.0005246. eCollection 2017 May.

42.

Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

Adema CM, Hillier LW, Jones CS, Loker ES, Knight M, Minx P, Oliveira G, Raghavan N, Shedlock A, do Amaral LR, Arican-Goktas HD, Assis JG, Baba EH, Baron OL, Bayne CJ, Bickham-Wright U, Biggar KK, Blouin M, Bonning BC, Botka C, Bridger JM, Buckley KM, Buddenborg SK, Lima Caldeira R, Carleton J, Carvalho OS, Castillo MG, Chalmers IW, Christensens M, Clifton S, Cosseau C, Coustau C, Cripps RM, Cuesta-Astroz Y, Cummins SF, di Stephano L, Dinguirard N, Duval D, Emrich S, Feschotte C, Feyereisen R, FitzGerald P, Fronick C, Fulton L, Galinier R, Gava SG, Geusz M, Geyer KK, Giraldo-Calderón GI, de Souza Gomes M, Gordy MA, Gourbal B, Grunau C, Hanington PC, Hoffmann KF, Hughes D, Humphries J, Jackson DJ, Jannotti-Passos LK, de Jesus Jeremias W, Jobling S, Kamel B, Kapusta A, Kaur S, Koene JM, Kohn AB, Lawson D, Lawton SP, Liang D, Limpanont Y, Liu S, Lockyer AE, Lovato TL, Ludolf F, Magrini V, McManus DP, Medina M, Misra M, Mitta G, Mkoji GM, Montague MJ, Montelongo C, Moroz LL, Munoz-Torres MC, Niazi U, Noble LR, Oliveira FS, Pais FS, Papenfuss AT, Peace R, Pena JJ, Pila EA, Quelais T, Raney BJ, Rast JP, Rollinson D, Rosse IC, Rotgans B, Routledge EJ, Ryan KM, Scholte LLS, Storey KB, Swain M, Tennessen JA, Tomlinson C, Trujillo DL, Volpi EV, Walker AJ, Wang T, Wannaporn I, Warren WC, Wu XJ, Yoshino TP, Yusuf M, Zhang SM, Zhao M, Wilson RK.

Nat Commun. 2017 May 16;8:15451. doi: 10.1038/ncomms15451. Erratum in: Nat Commun. 2017 Aug 23;8:16153.

43.

If you had measles would you want prophylactic antibiotics?

Chalmers I.

BMJ. 2017 May 8;357:j2172. doi: 10.1136/bmj.j2172. No abstract available.

PMID:
28483782
44.

What are funders doing to minimise waste in research?

Nasser M, Clarke M, Chalmers I, Brurberg KG, Nykvist H, Lund H, Glasziou P.

Lancet. 2017 Mar 11;389(10073):1006-1007. doi: 10.1016/S0140-6736(17)30657-8. No abstract available.

PMID:
28290987
45.

Evaluating Cinchona bark and quinine for treating and preventing malaria.

Gachelin G, Garner P, Ferroni E, Tröhler U, Chalmers I.

J R Soc Med. 2017 Feb;110(2):73-82. doi: 10.1177/0141076816688411. No abstract available.

46.

Can an educational podcast improve the ability of parents of primary school children to assess the reliability of claims made about the benefits and harms of treatments: study protocol for a randomised controlled trial.

Semakula D, Nsangi A, Oxman M, Austvoll-Dahlgren A, Rosenbaum S, Kaseje M, Nyirazinyoye L, Fretheim A, Chalmers I, Oxman AD, Sewankambo NK.

Trials. 2017 Jan 21;18(1):31. doi: 10.1186/s13063-016-1745-y.

47.

Evaluating Cinchona bark and quinine for treating and preventing malaria.

Gachelin G, Garner P, Ferroni E, Tröhler U, Chalmers I.

J R Soc Med. 2017 Jan;110(1):31-40. doi: 10.1177/0141076816681421. No abstract available.

48.

Towards evidence based research.

Lund H, Brunnhuber K, Juhl C, Robinson K, Leenaars M, Dorch BF, Jamtvedt G, Nortvedt MW, Christensen R, Chalmers I.

BMJ. 2016 Oct 21;355:i5440. doi: 10.1136/bmj.i5440. No abstract available.

PMID:
27797786
49.

J Guy Scadding and the move from alternation to randomisation.

Chalmers I, Clarke M.

J R Soc Med. 2016 Jul;109(7):282-3. doi: 10.1177/0141076816654655. No abstract available.

50.

Misrepresentation of the National Women's Hospital in Auckland, New Zealand.

Baird MA, Barlev N, Bryder L, Burls A, Carrell RW, Chalmers I, Cooper GJ, Dow DA, Hicks K, Keirse M, Mantell C, Nobbs P, Overton E, Overton H, Patten P, Sandercock J, Smith V, Trubuhovich R.

Am J Public Health. 2016 Jul;106(7):1208-9. doi: 10.2105/AJPH.2016.303162. No abstract available.

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