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Items: 1 to 50 of 413

1.

Production of metabolites of the anti-cancer drug noscapine using a P450BM3 mutant library.

Richards L, Lutz A, Chalmers DK, Jarrold A, Bowser T, Stevens GW, Gras SL.

Biotechnol Rep (Amst). 2019 Aug 24;24:e00372. doi: 10.1016/j.btre.2019.e00372. eCollection 2019 Dec.

2.

Animal-assisted therapy in a Canadian psychiatric prison.

Dell C, Chalmers D, Stobbe M, Rohr B, Husband A.

Int J Prison Health. 2019 Aug 29;15(3):209-231. doi: 10.1108/IJPH-04-2018-0020. Epub 2019 Mar 1.

PMID:
31329041
3.

Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa.

Elnahriry KA, Wai DCC, Krishnarjuna B, Badawy NN, Chittoor B, MacRaild CA, Williams-Noonan BJ, Surm JM, Chalmers DK, Zhang AH, Peigneur S, Mobli M, Tytgat J, Prentis P, Norton RS.

Toxicon. 2019 Oct;168:104-112. doi: 10.1016/j.toxicon.2019.07.002. Epub 2019 Jul 11.

PMID:
31302115
4.

Consent insufficient for data release.

Nicol D, Eckstein L, Bentzen HB, Borry P, Burgess M, Burke W, Chalmers D, Cho M, Dove E, Fullerton S, Ida R, Kato K, Kaye J, Koenig B, Manson S, McGrail K, Meslin E, O'Doherty K, Prainsack B, Shabani M, Tabor H, Thorogood A, de Vries J.

Science. 2019 May 3;364(6439):445-446. doi: 10.1126/science.aax0892. No abstract available.

PMID:
31048483
5.

A Nonionic Polyethylene Oxide (PEO) Surfactant Model: Experimental and Molecular Dynamics Studies of Kolliphor EL.

Suys EJA, Warren DB, Pham AC, Nowell CJ, Clulow AJ, Benameur H, Porter CJH, Pouton CW, Chalmers DK.

J Pharm Sci. 2019 Jan;108(1):193-204. doi: 10.1016/j.xphs.2018.11.028. Epub 2018 Nov 28.

PMID:
30502483
6.

Improvement in the Predicted Partitioning of Alcohol and Polyethylene Oxide Groups Between Water and Octanol (logP) in Molecular Dynamics Simulations.

Warren DB, McPhee E, Birru WA, Benameur H, Chalmers DK, Pouton CW.

J Pharm Sci. 2019 Jan;108(1):214-222. doi: 10.1016/j.xphs.2018.11.016. Epub 2018 Nov 20.

PMID:
30468829
7.

Controlled Construction of Cyclic d / l Peptide Nanorods.

Silk MR, Mohanty B, Sampson JB, Scanlon MJ, Thompson PE, Chalmers DK.

Angew Chem Int Ed Engl. 2019 Jan 8;58(2):596-601. doi: 10.1002/anie.201811910. Epub 2018 Dec 5.

PMID:
30452108
8.

Location of Solvated Probe Molecules Within Nonionic Surfactant Micelles Using Molecular Dynamics.

Warren DB, McPhee E, Birru WA, Benameur H, Chalmers DK, Pouton CW.

J Pharm Sci. 2019 Jan;108(1):205-213. doi: 10.1016/j.xphs.2018.10.055. Epub 2018 Nov 3.

PMID:
30395831
9.

A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.

Sadek MM, Barlow N, Leung EWW, Williams-Noonan BJ, Yap BK, Shariff FM, Caradoc-Davies TT, Nicholson SE, Chalmers DK, Thompson PE, Law RHP, Norton RS.

ACS Chem Biol. 2018 Oct 19;13(10):2930-2938. doi: 10.1021/acschembio.8b00561. Epub 2018 Sep 18.

PMID:
30226743
10.

Correction to: Australia: regulating genomic data sharing to promote public trust.

Eckstein L, Chalmers D, Critchley C, Jeanneret R, McWhirter R, Nielsen J, Otlowski M, Nicol D.

Hum Genet. 2018 Aug;137(8):593. doi: 10.1007/s00439-018-1930-z.

11.

Australia: regulating genomic data sharing to promote public trust.

Eckstein L, Chalmers D, Critchley C, Jeanneret R, McWhirter R, Nielsen J, Otlowski M, Nicol D.

Hum Genet. 2018 Aug;137(8):583-591. doi: 10.1007/s00439-018-1914-z. Epub 2018 Aug 16. Review. Erratum in: Hum Genet. 2018 Aug 23;:.

12.

The influence and manipulation of acid/base properties in drug discovery.

Manallack DT, Yuriev E, Chalmers DK.

Drug Discov Today Technol. 2018 Jul;27:41-47. doi: 10.1016/j.ddtec.2018.04.003. Epub 2018 Apr 26. Review.

PMID:
30103862
13.

Provenance and risk in transfer of biological materials.

Nielsen J, Bubela T, Chalmers DRC, Johns A, Kahl L, Kamens J, Lawson C, Liddicoat J, McWhirter R, Monotti A, Scheibner J, Whitton T, Nicol D.

PLoS Biol. 2018 Aug 13;16(8):e2006031. doi: 10.1371/journal.pbio.2006031. eCollection 2018 Aug.

14.

Cyclic Hexapeptide Mimics of the LEDGF Integrase Recognition Loop in Complex with HIV-1 Integrase.

Northfield SE, Wielens J, Headey SJ, Williams-Noonan BJ, Mulcair M, Scanlon MJ, Parker MW, Thompson PE, Chalmers DK.

ChemMedChem. 2018 Aug 10;13(15):1555-1565. doi: 10.1002/cmdc.201800129. Epub 2018 Jul 6.

PMID:
29862651
15.

Incidence and risk factors for positive urine culture at the time of pediatric urologic surgery.

Maccini MA, Chalmers DJ, Vemulakonda VM, Campbell JB.

Int Urol Nephrol. 2018 Jun;50(6):1017-1020. doi: 10.1007/s11255-018-1884-z. Epub 2018 May 21.

PMID:
29785658
16.

Polymeric Precipitation Inhibitors Promote Fenofibrate Supersaturation and Enhance Drug Absorption from a Type IV Lipid-Based Formulation.

Suys EJA, Chalmers DK, Pouton CW, Porter CJH.

Mol Pharm. 2018 Jun 4;15(6):2355-2371. doi: 10.1021/acs.molpharmaceut.8b00206. Epub 2018 May 4.

PMID:
29659287
17.

Including all voices in international data-sharing governance.

Kaye J, Terry SF, Juengst E, Coy S, Harris JR, Chalmers D, Dove ES, Budin-Ljøsne I, Adebamowo C, Ogbe E, Bezuidenhout L, Morrison M, Minion JT, Murtagh MJ, Minari J, Teare H, Isasi R, Kato K, Rial-Sebbag E, Marshall P, Koenig B, Cambon-Thomsen A.

Hum Genomics. 2018 Mar 7;12(1):13. doi: 10.1186/s40246-018-0143-9.

18.

Prospective study of enhanced recovery after surgery protocol in children undergoing reconstructive operations.

Rove KO, Brockel MA, Saltzman AF, Dönmez MI, Brodie KE, Chalmers DJ, Caldwell BT, Vemulakonda VM, Wilcox DT.

J Pediatr Urol. 2018 Jun;14(3):252.e1-252.e9. doi: 10.1016/j.jpurol.2018.01.001. Epub 2018 Feb 2.

PMID:
29398586
19.

Computational Models of the Intestinal Environment. 3. The Impact of Cholesterol Content and pH on Mixed Micelle Colloids.

Suys EJA, Warren DB, Porter CJH, Benameur H, Pouton CW, Chalmers DK.

Mol Pharm. 2017 Nov 6;14(11):3684-3697. doi: 10.1021/acs.molpharmaceut.7b00446. Epub 2017 Oct 5.

PMID:
28980815
20.

Key challenges in bringing CRISPR-mediated somatic cell therapy into the clinic.

Nicol D, Eckstein L, Morrison M, Sherkow JS, Otlowski M, Whitton T, Bubela T, Burdon KP, Chalmers D, Chan S, Charlesworth J, Critchley C, Crossley M, de Lacey S, Dickinson JL, Hewitt AW, Kamens J, Kato K, Kleiderman E, Kodama S, Liddicoat J, Mackey DA, Newson AJ, Nielsen J, Wagner JK, McWhirter RE.

Genome Med. 2017 Sep 25;9(1):85. doi: 10.1186/s13073-017-0475-4.

21.

A cross-sectional survey of Australian and New Zealand public opinion on methods totriage intensive care patients in an influenza pandemic.

Cheung W, Myburgh J, McGuinness S, Chalmers D, Parke R, Blyth F, Seppelt I, Parr M, Hooker C, Blackwell N, DeMonte S, Gandhi K, Kol M, Kerridge I, Nair P, Saunders NM, Saxena MK, Thanakrishnan G, Naganathan V; Influenza Pandemic ICU Triage 3 study investigators; Australian and New Zealand Intensive Care Society Clinical Trials Group.

Crit Care Resusc. 2017 Sep;19(3):254-265.

PMID:
28866976
22.

How kanamycin A interacts with bacterial and mammalian mimetic membranes.

John T, Thomas T, Abel B, Wood BR, Chalmers DK, Martin LL.

Biochim Biophys Acta Biomembr. 2017 Nov;1859(11):2242-2252. doi: 10.1016/j.bbamem.2017.08.016. Epub 2017 Aug 26.

23.

Free Energy Methods in Drug Design: Prospects of "Alchemical Perturbation" in Medicinal Chemistry.

Williams-Noonan BJ, Yuriev E, Chalmers DK.

J Med Chem. 2018 Feb 8;61(3):638-649. doi: 10.1021/acs.jmedchem.7b00681. Epub 2017 Aug 4.

PMID:
28745501
24.

Slip-additive migration, surface morphology, and performance on injection moulded high-density polyethylene closures.

Dulal N, Shanks R, Gengenbach T, Gill H, Chalmers D, Adhikari B, Pardo Martinez I.

J Colloid Interface Sci. 2017 Nov 1;505:537-545. doi: 10.1016/j.jcis.2017.06.040. Epub 2017 Jun 13.

PMID:
28645037
25.

Comparison of systemic pharmacodynamic effects of two combination pressurized metered dose inhalers that deliver salmeterol and fluticasone propionate.

Harrison LI, Sessions V, Wiggenhorn CJ, Chalmers D, Leung P, Efthimiou J.

Br J Clin Pharmacol. 2017 Nov;83(11):2377-2385. doi: 10.1111/bcp.13349. Epub 2017 Aug 1.

26.

Parallel and antiparallel cyclic d/l peptide nanotubes.

Silk MR, Newman J, Ratcliffe JC, White JF, Caradoc-Davies T, Price JR, Perrier S, Thompson PE, Chalmers DK.

Chem Commun (Camb). 2017 Jun 21;53(49):6613-6616. doi: 10.1039/c7cc00846e. Epub 2017 Jun 5.

PMID:
28581562
27.

Ethics and Governance of Stem Cell Banks.

Chalmers D, Rathjen P, Rathjen J, Nicol D.

Methods Mol Biol. 2017;1590:99-112. doi: 10.1007/978-1-4939-6921-0_7. Review.

PMID:
28353264
28.

Structure and activity of contryphan-Vc2: Importance of the d-amino acid residue.

Drane SB, Robinson SD, MacRaild CA, Chhabra S, Chittoor B, Morales RA, Leung EW, Belgi A, Espino SS, Olivera BM, Robinson AJ, Chalmers DK, Norton RS.

Toxicon. 2017 Apr;129:113-122. doi: 10.1016/j.toxicon.2017.02.012. Epub 2017 Feb 17.

PMID:
28216409
29.

Computational Models of the Gastrointestinal Environment. 1. The Effect of Digestion on the Phase Behavior of Intestinal Fluids.

Birru WA, Warren DB, Headey SJ, Benameur H, Porter CJ, Pouton CW, Chalmers DK.

Mol Pharm. 2017 Mar 6;14(3):566-579. doi: 10.1021/acs.molpharmaceut.6b00888. Epub 2017 Feb 15.

PMID:
28099023
30.

Computational Models of the Gastrointestinal Environment. 2. Phase Behavior and Drug Solubilization Capacity of a Type I Lipid-Based Drug Formulation after Digestion.

Birru WA, Warren DB, Han S, Benameur H, Porter CJ, Pouton CW, Chalmers DK.

Mol Pharm. 2017 Mar 6;14(3):580-592. doi: 10.1021/acs.molpharmaceut.6b00887. Epub 2017 Feb 15.

PMID:
27936778
31.

Determination of ligand binding modes in weak protein-ligand complexes using sparse NMR data.

Mohanty B, Williams ML, Doak BC, Vazirani M, Ilyichova O, Wang G, Bermel W, Simpson JS, Chalmers DK, King GF, Mobli M, Scanlon MJ.

J Biomol NMR. 2016 Nov;66(3):195-208. Epub 2016 Oct 24.

PMID:
27778134
32.

Inter-rater reliability of the APD, SFU and UTD grading systems in fetal sonography and MRI.

Chalmers DJ, Meyers ML, Brodie KE, Palmer C, Campbell JB.

J Pediatr Urol. 2016 Oct;12(5):305.e1-305.e5. doi: 10.1016/j.jpurol.2016.06.012. Epub 2016 Jul 27.

PMID:
27567594
33.

Structure-Activity Studies of β-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.

Wang G, Drinkwater N, Drew DR, MacRaild CA, Chalmers DK, Mohanty B, Lim SS, Anders RF, Beeson JG, Thompson PE, McGowan S, Simpson JS, Norton RS, Scanlon MJ.

J Mol Biol. 2016 Oct 9;428(20):3986-3998. doi: 10.1016/j.jmb.2016.07.001. Epub 2016 Jul 14.

PMID:
27422009
34.

Has the biobank bubble burst? Withstanding the challenges for sustainable biobanking in the digital era.

Chalmers D, Nicol D, Kaye J, Bell J, Campbell AV, Ho CW, Kato K, Minari J, Ho CH, Mitchell C, Molnár-Gábor F, Otlowski M, Thiel D, Fullerton SM, Whitton T.

BMC Med Ethics. 2016 Jul 12;17(1):39. doi: 10.1186/s12910-016-0124-2. Review.

35.

Beta amino acid-modified and fluorescently labelled kisspeptin analogues with potent KISS1R activity.

Camerino MA, Liu M, Moriya S, Kitahashi T, Mahgoub A, Mountford SJ, Chalmers DK, Soga T, Parhar IS, Thompson PE.

J Pept Sci. 2016 Jun;22(6):406-14. doi: 10.1002/psc.2883.

PMID:
27282137
36.

Pediatric Urology for the General Surgeon.

Chalmers DJ, Vemulakonda VM.

Surg Clin North Am. 2016 Jun;96(3):545-65. doi: 10.1016/j.suc.2016.02.010. Review.

PMID:
27261794
37.

Design, Synthesis, and Characterization of Cyclic Peptidomimetics of the Inducible Nitric Oxide Synthase Binding Epitope That Disrupt the Protein-Protein Interaction Involving SPRY Domain-Containing Suppressor of Cytokine Signaling Box Protein (SPSB) 2 and Inducible Nitric Oxide Synthase.

Harjani JR, Yap BK, Leung EW, Lucke A, Nicholson SE, Scanlon MJ, Chalmers DK, Thompson PE, Norton RS, Baell JB.

J Med Chem. 2016 Jun 23;59(12):5799-809. doi: 10.1021/acs.jmedchem.6b00386. Epub 2016 Jun 8.

PMID:
27214043
38.

Editorial response to JPUROL-D-15-00312: Study of clitoral hood anatomy in the pediatric population.

Chalmers D.

J Pediatr Urol. 2016 Jun;12(3):178. doi: 10.1016/j.jpurol.2016.01.006. Epub 2016 Feb 18. No abstract available.

PMID:
26961281
39.

Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction.

Yap BK, Harjani JR, Leung EW, Nicholson SE, Scanlon MJ, Chalmers DK, Thompson PE, Baell JB, Norton RS.

FEBS Lett. 2016 Mar;590(6):696-704. doi: 10.1002/1873-3468.12115. Epub 2016 Mar 6.

40.

The Helping Horse: How Equine Assisted Learning Contributes to the Wellbeing of First Nations Youth in Treatment for Volatile Substance Misuse.

Adams C, Arratoon C, Boucher J, Cartier G, Chalmers D, Dell CA, Dell D, Dryka D, Duncan R, Dunn K, Hopkins C, Longclaws L, MacKinnon T, Sauve E, Spence S, Wuttunee M.

Hum Anim Interact Bull. 2015 Jun;1(1):52-75.

41.

A decision tool to guide the ethics review of a challenging breed of emerging genomic projects.

Joly Y, So D, Osien G, Crimi L, Bobrow M, Chalmers D, Wallace SE, Zeps N, Knoppers B.

Eur J Hum Genet. 2016 Aug;24(8):1099-103. doi: 10.1038/ejhg.2015.279. Epub 2016 Jan 20. Review.

42.

Is Australia Well Equipped to Deal with Future Clinical Trials?

Eckstein L, Chalmers D.

J Law Med. 2016;24(2):337-41.

PMID:
30137707
43.

Biobanking and Privacy Laws in Australia.

Chalmers D.

J Law Med Ethics. 2015 Winter;43(4):703-13. doi: 10.1111/jlme.12313.

PMID:
26711411
44.

Ligand Binding Pathways of Clozapine and Haloperidol in the Dopamine D2 and D3 Receptors.

Thomas T, Fang Y, Yuriev E, Chalmers DK.

J Chem Inf Model. 2016 Feb 22;56(2):308-21. doi: 10.1021/acs.jcim.5b00457. Epub 2016 Feb 2.

PMID:
26690887
45.

Are Preexisting Retinal and Central Nervous System-Related Comorbidities Risk Factors for Complications Following Robotic-Assisted Laparoscopic Prostatectomy?

Chalmers D, Cusano A, Haddock P, Staff I, Wagner J.

Int Braz J Urol. 2015 Jul-Aug;41(4):661-8. doi: 10.1590/S1677-5538.IBJU.2014.0464.

46.

Fragment Based Strategies for Discovery of Novel HIV-1 Reverse Transcriptase and Integrase Inhibitors.

Latham CF, La J, Tinetti RN, Chalmers DK, Tachedjian G.

Curr Top Med Chem. 2016;16(10):1135-53. Review.

PMID:
26324045
47.

Clean intermittent catheterization as an initial management strategy provides for adequate preservation of renal function in newborns with persistent cloaca.

Chalmers DJ, Rove KO, Wiedel CA, Tong S, Siparsky GL, Wilcox DT.

J Pediatr Urol. 2015 Aug;11(4):211.e1-4. doi: 10.1016/j.jpurol.2015.05.014. Epub 2015 Jun 12.

PMID:
26187141
48.

Applying One Health to the Study of Animal-Assisted Interventions.

Chalmers D, Dell CA.

Ecohealth. 2015 Dec;12(4):560-2. doi: 10.1007/s10393-015-1042-3. Epub 2015 Jun 11.

49.

Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening.

La J, Latham CF, Tinetti RN, Johnson A, Tyssen D, Huber KD, Sluis-Cremer N, Simpson JS, Headey SJ, Chalmers DK, Tachedjian G.

Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):6979-84. doi: 10.1073/pnas.1423900112. Epub 2015 May 18.

50.

Symptomatic infundibulopelvic dysgenesis in an adolescent.

Pitts D, Chalmers D, Jumper B.

Case Rep Urol. 2015;2015:307319. doi: 10.1155/2015/307319. Epub 2015 Apr 9.

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