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Optimization of LED Lighting for Clinical Settings.

Soltic S, Chalmers A.

J Healthc Eng. 2019 Aug 27;2019:5016013. doi: 10.1155/2019/5016013. eCollection 2019.


Glutamatergic synaptic input to glioma cells drives brain tumour progression.

Venkataramani V, Tanev DI, Strahle C, Studier-Fischer A, Fankhauser L, Kessler T, Körber C, Kardorff M, Ratliff M, Xie R, Horstmann H, Messer M, Paik SP, Knabbe J, Sahm F, Kurz FT, Acikgöz AA, Herrmannsdörfer F, Agarwal A, Bergles DE, Chalmers A, Miletic H, Turcan S, Mawrin C, Hänggi D, Liu HK, Wick W, Winkler F, Kuner T.

Nature. 2019 Sep 18. doi: 10.1038/s41586-019-1564-x. [Epub ahead of print]


Stereotactic ablative radiotherapy for the comprehensive treatment of 4-10 oligometastatic tumors (SABR-COMET-10): study protocol for a randomized phase III trial.

Palma DA, Olson R, Harrow S, Correa RJM, Schneiders F, Haasbeek CJA, Rodrigues GB, Lock M, Yaremko BP, Bauman GS, Ahmad B, Schellenberg D, Liu M, Gaede S, Laba J, Mulroy L, Senthi S, Louie AV, Swaminath A, Chalmers A, Warner A, Slotman BJ, de Gruijl TD, Allan A, Senan S.

BMC Cancer. 2019 Aug 19;19(1):816. doi: 10.1186/s12885-019-5977-6.


Pre-EDIT: A Randomized Feasibility Trial of Elastance-Directed Intrapleural Catheter or Talc Pleurodesis in Malignant Pleural Effusion.

Martin GA, Tsim S, Kidd AC, Foster JE, McLoone P, Chalmers A, Blyth KG.

Chest. 2019 Jul 30. pii: S0012-3692(19)31384-4. doi: 10.1016/j.chest.2019.07.010. [Epub ahead of print]


Stacked in-plane histology for quantitative validation of non-invasive imaging biomarkers: Application to an infiltrative brain tumour model.

Al-Mubarak H, Vallatos A, Gallagher L, Birch JL, Gilmour L, Foster JE, Chalmers AJ, Holmes WM.

J Neurosci Methods. 2019 Oct 1;326:108372. doi: 10.1016/j.jneumeth.2019.108372. Epub 2019 Jul 23.


Phase I Trial of Targeted EGFR or ALK Therapy with Ipilimumab in Metastatic NSCLC with Long-Term Follow-Up.

Chalmers AW, Patel S, Boucher K, Cannon L, Esplin M, Luckart J, Graves N, Van Duren T, Akerley W.

Target Oncol. 2019 Aug;14(4):417-421. doi: 10.1007/s11523-019-00658-0.


Focused very high-energy electron beams as a novel radiotherapy modality for producing high-dose volumetric elements.

Kokurewicz K, Brunetti E, Welsh GH, Wiggins SM, Boyd M, Sorensen A, Chalmers AJ, Schettino G, Subiel A, DesRosiers C, Jaroszynski DA.

Sci Rep. 2019 Jul 25;9(1):10837. doi: 10.1038/s41598-019-46630-w.


Contribution of Human Hair in Solar UV Transmission in Skin: Implications for Melanoma Development.

Huang X, Protheroe MD, Al-Jumaily AM, Paul SP, Chalmers AN, Wang S, Diwu J, Liu W.

Ann Biomed Eng. 2019 Jul 9. doi: 10.1007/s10439-019-02315-z. [Epub ahead of print]


Assembling the brain trust: the multidisciplinary imperative in neuro-oncology.

Ludmir EB, Mahajan A, Ahern V, Ajithkumar T, Alapetite C, Bernier-Chastagner V, Bindra RS, Bishop AJ, Bolle S, Brown PD, Carrie C, Chalmers AJ, Chang EL, Chung C, Dieckmann K, Esiashvili N, Gandola L, Ghia AJ, Gondi V, Grosshans DR, Harrabi SB, Horan G, Indelicato DJ, Jalali R, Janssens GO, Krause M, Laack NN, Laperriere N, Laprie A, Li J, Marcus KJ, McGovern SL, Merchant TE, Merrell KW, Padovani L, Parkes J, Paulino AC, Schwarz R, Shih HA, Souhami L, Sulman EP, Taylor RE, Thorp N, Timmermann B, Wheeler G, Wolden SL, Woodhouse KD, Yeboa DN, Yock TI, Kortmann RD, McAleer MF.

Nat Rev Clin Oncol. 2019 Aug;16(8):521-522. doi: 10.1038/s41571-019-0235-z. No abstract available.


Patient-specific 3D-printed glioblastomas.

Gomez-Roman N, Chalmers AJ.

Nat Biomed Eng. 2019 Jul;3(7):498-499. doi: 10.1038/s41551-019-0379-2. No abstract available.


Simulation of UV power absorbed by follicular stem cells during sun exposure and possible implications for melanoma development.

Huang X, Protheroe MD, Al-Jumaily AM, Chalmers AN, Paul SP, Fu X.

J Opt Soc Am A Opt Image Sci Vis. 2019 Apr 1;36(4):628-635. doi: 10.1364/JOSAA.36.000628.


Audio-Visual-Olfactory Resource Allocation for Tri-modal Virtual Environments.

Doukakis E, Debattista K, Bashford-Rogers T, Dhokia A, Asadipour A, Chalmers A, Harvey C.

IEEE Trans Vis Comput Graph. 2019 May;25(5):1865-1875. doi: 10.1109/TVCG.2019.2898823. Epub 2019 Feb 14.


A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications.

Gobin M, Nazarov PV, Warta R, Timmer M, Reifenberger G, Felsberg J, Vallar L, Chalmers AJ, Herold-Mende CC, Goldbrunner R, Niclou SP, Van Dyck E.

Cancer Res. 2019 Mar 15;79(6):1226-1238. doi: 10.1158/0008-5472.CAN-18-2076. Epub 2019 Jan 23.


Glioblastoma's Next Top Model: Novel Culture Systems for Brain Cancer Radiotherapy Research.

Caragher S, Chalmers AJ, Gomez-Roman N.

Cancers (Basel). 2019 Jan 4;11(1). pii: E44. doi: 10.3390/cancers11010044. Review.


Adverse Event Management in Patients with BRAF V600E-Mutant Non-Small Cell Lung Cancer Treated with Dabrafenib plus Trametinib.

Chalmers A, Cannon L, Akerley W.

Oncologist. 2019 Jul;24(7):963-972. doi: 10.1634/theoncologist.2018-0296. Epub 2018 Dec 31.


Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region.

Vallatos A, Al-Mubarak HFI, Birch JL, Galllagher L, Mullin JM, Gilmour L, Holmes WM, Chalmers AJ.

J Magn Reson Imaging. 2019 Aug;50(2):529-540. doi: 10.1002/jmri.26580. Epub 2018 Dec 19.


Evaluation of four different small animal radiation plans on tumour and normal tissue dosimetry in a glioblastoma mouse model.

Rutherford A, Stevenson K, Tulk A, Chalmers AJ.

Br J Radiol. 2019 Mar;92(1095):20180469. doi: 10.1259/bjr.20180469. Epub 2018 Nov 7.


Fruit characteristics, phytochemical and antioxidant properties of blueberry ash (Elaeocarpus reticulatus).

Vuong QV, Ngoc Thuy Pham H, Vu HT, Dang TT, Van Ngo T, Chalmers AC.

Heliyon. 2018 Oct 5;4(10):e00834. doi: 10.1016/j.heliyon.2018.e00834. eCollection 2018 Oct.


A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma.

Birch JL, Strathdee K, Gilmour L, Vallatos A, McDonald L, Kouzeli A, Vasan R, Qaisi AH, Croft DR, Crighton D, Gill K, Gray CH, Konczal J, Mezna M, McArthur D, Schüttelkopf AW, McConnell P, Sime M, Holmes WM, Bower J, McKinnon HJ, Drysdale M, Olson MF, Chalmers AJ.

Cancer Res. 2018 Nov 15;78(22):6509-6522. doi: 10.1158/0008-5472.CAN-18-1697. Epub 2018 Oct 2.


Radiation-Induced Transformation of Immunoregulatory Networks in the Tumor Stroma.

Martinez-Zubiaurre I, Chalmers AJ, Hellevik T.

Front Immunol. 2018 Jul 26;9:1679. doi: 10.3389/fimmu.2018.01679. eCollection 2018. Review.


Practice-changing radiation therapy trials for the treatment of cancer: where are we 150 years after the birth of Marie Curie?

Thompson MK, Poortmans P, Chalmers AJ, Faivre-Finn C, Hall E, Huddart RA, Lievens Y, Sebag-Montefiore D, Coles CE.

Br J Cancer. 2018 Aug;119(4):389-407. doi: 10.1038/s41416-018-0201-z. Epub 2018 Jul 31. Review.


Replication Stress Drives Constitutive Activation of the DNA Damage Response and Radioresistance in Glioblastoma Stem-like Cells.

Carruthers RD, Ahmed SU, Ramachandran S, Strathdee K, Kurian KM, Hedley A, Gomez-Roman N, Kalna G, Neilson M, Gilmour L, Stevenson KH, Hammond EM, Chalmers AJ.

Cancer Res. 2018 Sep 1;78(17):5060-5071. doi: 10.1158/0008-5472.CAN-18-0569. Epub 2018 Jul 5.


An Array of Bioactive Compounds From Australian Eucalypts and Their Relevance in Pancreatic Cancer Therapeutics.

Bhuyan DJ, Vuong QV, Chalmers AC, Bowyer MC, Scarlett CJ.

Pancreas. 2018 Jul;47(6):690-707. doi: 10.1097/MPA.0000000000001074. Review.


Eucalyptus microcorys leaf extract derived HPLC-fraction reduces the viability of MIA PaCa-2 cells by inducing apoptosis and arresting cell cycle.

Bhuyan DJ, Vuong QV, Bond DR, Chalmers AC, Bowyer MC, Scarlett CJ.

Biomed Pharmacother. 2018 Sep;105:449-460. doi: 10.1016/j.biopha.2018.05.150. Epub 2018 Jun 5.


Pre-EDIT: protocol for a randomised feasibility trial of elastance-directed intrapleural catheter or talc pleurodesis (EDIT) in malignant pleural effusion.

Martin GA, Tsim S, Kidd AC, Foster JE, McLoone P, Chalmers A, Blyth KG.

BMJ Open Respir Res. 2018 May 29;5(1):e000293. doi: 10.1136/bmjresp-2018-000293. eCollection 2018.


Health economic evaluation of a serum-based blood test for brain tumour diagnosis: exploration of two clinical scenarios.

Gray E, Butler HJ, Board R, Brennan PM, Chalmers AJ, Dawson T, Goodden J, Hamilton W, Hegarty MG, James A, Jenkinson MD, Kernick D, Lekka E, Livermore LJ, Mills SJ, O'Neill K, Palmer DS, Vaqas B, Baker MJ.

BMJ Open. 2018 May 24;8(5):e017593. doi: 10.1136/bmjopen-2017-017593.


Review of human hair optical properties in possible relation to melanoma development.

Huang X, Protheroe MD, Al-Jumaily AM, Paul SP, Chalmers AN.

J Biomed Opt. 2018 May;23(5):1-9. doi: 10.1117/1.JBO.23.5.050901.


Immunotherapy after chemoradiotherapy in stage III non-small cell lung cancer: a new standard of care?

Chalmers AW, Patel SB, Akerley W.

J Thorac Dis. 2018 Mar;10(3):1198-1200. doi: 10.21037/jtd.2018.01.160. No abstract available.


An 18F-Labeled Poly(ADP-ribose) Polymerase Positron Emission Tomography Imaging Agent.

Zmuda F, Blair A, Liuzzi MC, Malviya G, Chalmers AJ, Lewis D, Sutherland A, Pimlott SL.

J Med Chem. 2018 May 10;61(9):4103-4114. doi: 10.1021/acs.jmedchem.8b00138. Epub 2018 Apr 19.


SYSTEMS-2: A randomised phase II study of radiotherapy dose escalation for pain control in malignant pleural mesothelioma.

Ashton M, O'Rourke N, Macleod N, Laird B, Stobo J, Kelly C, Alexander L, Franks K, Moore K, Currie S, Valentine R, Chalmers AJ.

Clin Transl Radiat Oncol. 2017 Nov 21;8:45-49. doi: 10.1016/j.ctro.2017.11.004. eCollection 2018 Jan.


PARADIGM-2: Two parallel phase I studies of olaparib and radiotherapy or olaparib and radiotherapy plus temozolomide in patients with newly diagnosed glioblastoma, with treatment stratified by MGMT status.

Fulton B, Short SC, James A, Nowicki S, McBain C, Jefferies S, Kelly C, Stobo J, Morris A, Williamson A, Chalmers AJ.

Clin Transl Radiat Oncol. 2017 Nov 21;8:12-16. doi: 10.1016/j.ctro.2017.11.003. eCollection 2018 Jan.


Associations Between Sleep Hygiene and Sleep Problems in Adolescents With ADHD: A Cross-Sectional Study.

Martin CA, Hiscock H, Rinehart N, Heussler HS, Hyde C, Fuller-Tyszkiewicz M, McGillivray J, Austin DW, Chalmers A, Sciberras E.

J Atten Disord. 2018 Mar 1:1087054718762513. doi: 10.1177/1087054718762513. [Epub ahead of print]


Durable response to osimertinib in EGFR mutated T790M wildtype non-small cell lung cancer with leptomeningeal metastases: A case report.

Chalmers A, Jensen L, Akerley W.

Lung Cancer. 2017 Dec;114:68-69. doi: 10.1016/j.lungcan.2017.10.009. Epub 2017 Oct 26.


Nonlinear dynamics of early atherosclerotic plaque formation may determine the efficacy of high density lipoproteins (HDL) in plaque regression.

Chalmers AD, Bursill CA, Myerscough MR.

PLoS One. 2017 Nov 21;12(11):e0187674. doi: 10.1371/journal.pone.0187674. eCollection 2017.


The role of radical radiotherapy in the management of malignant pleural mesothelioma: A systematic review.

Ashton M, O'Rourke N, Currie S, Rimner A, Chalmers A.

Radiother Oncol. 2017 Oct;125(1):1-12. doi: 10.1016/j.radonc.2017.08.003. Epub 2017 Aug 28. Review.


Cell surface dynamics and cellular distribution of endogenous FcRn.

D'Hooghe L, Chalmers AD, Heywood S, Whitley P.

PLoS One. 2017 Aug 17;12(8):e0182695. doi: 10.1371/journal.pone.0182695. eCollection 2017.


Challenges to Treating Older Glioblastoma Patients: the Influence of Clinical and Tumour Characteristics on Survival Outcomes.

Lorimer CF, Hanna C, Saran F, Chalmers A, Brock J.

Clin Oncol (R Coll Radiol). 2017 Nov;29(11):739-747. doi: 10.1016/j.clon.2017.05.010. Epub 2017 Aug 12.


GBM radiosensitizers: dead in the water…or just the beginning?

Bindra RS, Chalmers AJ, Evans S, Dewhirst M.

J Neurooncol. 2017 Sep;134(3):513-521. doi: 10.1007/s11060-017-2427-7. Epub 2017 Jul 31. Review.


A subset of high Gleason grade prostate carcinomas contain a large burden of prostate cancer syndecan-1 positive stromal cells.

Sharpe B, Alghezi DA, Cattermole C, Beresford M, Bowen R, Mitchard J, Chalmers AD.

Prostate. 2017 May;77(13):1312-1324. doi: 10.1002/pros.23391. Epub 2017 Jul 26.


Multiple boli arterial spin labeling for high signal-to-noise rodent brain perfusion imaging.

Vallatos A, Gilmour L, Chalmers AJ, Holmes WM.

Magn Reson Med. 2018 Feb;79(2):1020-1030. doi: 10.1002/mrm.26706. Epub 2017 May 17.


In vitro anticancer properties of selected Eucalyptus species.

Bhuyan DJ, Sakoff J, Bond DR, Predebon M, Vuong QV, Chalmers AC, van Altena IA, Bowyer MC, Scarlett CJ.

In Vitro Cell Dev Biol Anim. 2017 Aug;53(7):604-615. doi: 10.1007/s11626-017-0149-y. Epub 2017 Apr 27.


MR360: Mixed Reality Rendering for 360° Panoramic Videos.

Rhee T, Petikam L, Allen B, Chalmers A.

IEEE Trans Vis Comput Graph. 2017 Apr;23(4):1379-1388. doi: 10.1109/TVCG.2017.2657178. Epub 2017 Jan 23.


Study of diffusion weighted MRI as a predictive biomarker of response during radiotherapy for high and intermediate risk squamous cell cancer of the oropharynx: The MeRInO study.

Paterson C, Allwood-Spiers S, McCrea I, Foster J, McJury M, Thomson M, Sankaralingam M, Grose D, James A, Rizwanullah M, McLoone P, Chalmers A, Duffton A.

Clin Transl Radiat Oncol. 2017 Jan 10;2:13-18. doi: 10.1016/j.ctro.2016.12.003. eCollection 2017 Feb.


Exploring the Least Studied Australian Eucalypt Genera: Corymbia and Angophora for Phytochemicals with Anticancer Activity against Pancreatic Malignancies.

Bhuyan DJ, Vuong QV, Bond DR, Chalmers AC, van Altena IA, Bowyer MC, Scarlett CJ.

Chem Biodivers. 2017 Mar;14(3). doi: 10.1002/cbdv.201600291. Epub 2017 Feb 22.


Diagnostic and Prognostic Biomarkers in the Rational Assessment of Mesothelioma (DIAPHRAGM) study: protocol of a prospective, multicentre, observational study.

Tsim S, Kelly C, Alexander L, McCormick C, Thomson F, Woodward R, Foster JE, Stobo DB, Paul J, Maskell NA, Chalmers A, Blyth KG.

BMJ Open. 2016 Nov 24;6(11):e013324. doi: 10.1136/bmjopen-2016-013324.


PP2A Inhibitor PME-1 Drives Kinase Inhibitor Resistance in Glioma Cells.

Kaur A, Denisova OV, Qiao X, Jumppanen M, Peuhu E, Ahmed SU, Raheem O, Haapasalo H, Eriksson J, Chalmers AJ, Laakkonen P, Westermarck J.

Cancer Res. 2016 Dec 1;76(23):7001-7011. Epub 2016 Sep 26.


The Challenges Faced in Developing Novel Drug Radiation Combinations in Non-small Cell Lung Cancer.

Harrow S, Hanna GG, Faivre-Finn C, McDonald F, Chalmers AJ.

Clin Oncol (R Coll Radiol). 2016 Nov;28(11):720-725. doi: 10.1016/j.clon.2016.08.004. Epub 2016 Aug 31. Review.


A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses.

Gomez-Roman N, Stevenson K, Gilmour L, Hamilton G, Chalmers AJ.

Neuro Oncol. 2017 Feb 1;19(2):229-241. doi: 10.1093/neuonc/now164.

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