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Items: 14

1.

Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.

Perni M, Flagmeier P, Limbocker R, Cascella R, Aprile FA, Galvagnion C, Heller GT, Meisl G, Chen SW, Kumita JR, Challa PK, Kirkegaard JB, Cohen SIA, Mannini B, Barbut D, Nollen EAA, Cecchi C, Cremades N, Knowles TPJ, Chiti F, Zasloff M, Vendruscolo M, Dobson CM.

ACS Chem Biol. 2018 Jun 28. doi: 10.1021/acschembio.8b00466. [Epub ahead of print]

PMID:
29953201
2.

Enhancing the Resolution of Micro Free Flow Electrophoresis through Spatially Controlled Sample Injection.

Saar KL, Müller T, Charmet J, Challa PK, Knowles TPJ.

Anal Chem. 2018 Jul 9. doi: 10.1021/acs.analchem.8b01205. [Epub ahead of print]

PMID:
29938505
3.

Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery.

Perni M, Challa PK, Kirkegaard JB, Limbocker R, Koopman M, Hardenberg MC, Sormanni P, Müller T, Saar KL, Roode LWY, Habchi J, Vecchi G, Fernando N, Casford S, Nollen EAA, Vendruscolo M, Dobson CM, Knowles TPJ.

J Neurosci Methods. 2018 Aug 1;306:57-67. doi: 10.1016/j.jneumeth.2018.02.005. Epub 2018 Feb 13.

PMID:
29452179
4.

Real-Time Intrinsic Fluorescence Visualization and Sizing of Proteins and Protein Complexes in Microfluidic Devices.

Challa PK, Peter Q, Wright MA, Zhang Y, Saar KL, Carozza JA, Benesch JLP, Knowles TPJ.

Anal Chem. 2018 Mar 20;90(6):3849-3855. doi: 10.1021/acs.analchem.7b04523. Epub 2018 Feb 28.

PMID:
29451779
5.

Enhanced Quality Factor Label-free Biosensing with Micro-Cantilevers Integrated into Microfluidic Systems.

Kartanas T, Ostanin V, Challa PK, Daly R, Charmet J, Knowles TPJ.

Anal Chem. 2017 Nov 21;89(22):11929-11936. doi: 10.1021/acs.analchem.7b01174. Epub 2017 Nov 3.

PMID:
28984439
6.

Gradient-free determination of isoelectric points of proteins on chip.

Łapińska U, Saar KL, Yates EV, Herling TW, Müller T, Challa PK, Dobson CM, Knowles TPJ.

Phys Chem Chem Phys. 2017 Aug 30;19(34):23060-23067. doi: 10.1039/c7cp01503h.

PMID:
28817152
7.

Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning.

Challa PK, Kartanas T, Charmet J, Knowles TP.

Biomicrofluidics. 2017 Feb 17;11(1):014113. doi: 10.1063/1.4976690. eCollection 2017 Jan.

8.

A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity.

Perni M, Galvagnion C, Maltsev A, Meisl G, Müller MB, Challa PK, Kirkegaard JB, Flagmeier P, Cohen SI, Cascella R, Chen SW, Limbocker R, Sormanni P, Heller GT, Aprile FA, Cremades N, Cecchi C, Chiti F, Nollen EA, Knowles TP, Vendruscolo M, Bax A, Zasloff M, Dobson CM.

Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E1009-E1017. doi: 10.1073/pnas.1610586114. Epub 2017 Jan 17. Erratum in: Proc Natl Acad Sci U S A. 2017 Mar 21;114(12 ):E2543. Limboker, Ryan [corrected to Limbocker, Ryan].

9.

Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease.

Habchi J, Chia S, Limbocker R, Mannini B, Ahn M, Perni M, Hansson O, Arosio P, Kumita JR, Challa PK, Cohen SI, Linse S, Dobson CM, Knowles TP, Vendruscolo M.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):E200-E208. doi: 10.1073/pnas.1615613114. Epub 2016 Dec 23.

10.

Twist-bend nematic liquid crystals in high magnetic fields.

Challa PK, Borshch V, Parri O, Imrie CT, Sprunt SN, Gleeson JT, Lavrentovich OD, Jákli A.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Jun;89(6):060501. Epub 2014 Jun 6.

PMID:
25019707
11.

Magnetic-field-induced suppression of the amorphous blue phase.

Challa PK, Sprunt SN, Jákli A, Gleeson JT.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Jan;89(1):010501. Epub 2014 Jan 6.

PMID:
24580157
12.

Light scattering from liquid crystal director fluctuations in steady magnetic fields up to 25 tesla.

Challa PK, Curtiss O, Williams JC, Twieg R, Toth J, McGill S, Jákli A, Gleeson JT, Sprunt SN.

Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Jul;86(1 Pt 1):011708. Epub 2012 Jul 23.

PMID:
23005438
13.

Atrial fibrillation: update on ablation strategies and technology.

Challa PK, Mansour M.

Curr Cardiol Rep. 2011 Oct;13(5):394-8. doi: 10.1007/s11886-011-0205-2. Review.

PMID:
21809114

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