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Items: 16

1.

Exercise Mediated Nrf2 Signaling Protects the Myocardium From Isoproterenol-Induced Pathological Remodeling.

Shanmugam G, Challa AK, Devarajan A, Athmanathan B, Litovsky SH, Krishnamurthy P, Davidson CJ, Rajasekaran NS.

Front Cardiovasc Med. 2019 Jun 6;6:68. doi: 10.3389/fcvm.2019.00068. eCollection 2019.

2.

Integrating CRISPR-Cas9 Technology into Undergraduate Courses: Perspectives from a National Science Foundation (NSF) Workshop for Undergraduate Faculty, June 2018.

Wolyniak MJ, Austin S, Bloodworth LF 3rd, Carter D, Harrison SH, Hoage T, Hollis-Brown L, Jefferson F, Krufka A, Safadi-Chamberlin F, Santisteban MS, Soneral P, VanWinkle B, Challa AK.

J Microbiol Biol Educ. 2019 Apr 26;20(1). pii: 20.1.19. doi: 10.1128/jmbe.v20i1.1702. eCollection 2019.

3.

Enhanced Keap1-Nrf2 signaling protects the myocardium from isoproterenol-induced pathological remodeling in mice.

Shanmugam G, Challa AK, Litovsky SH, Devarajan A, Wang D, Jones DP, Darley-Usmar VM, Rajasekaran NS.

Redox Biol. 2019 May 4:101212. doi: 10.1016/j.redox.2019.101212. [Epub ahead of print]

4.

A mixing heteroduplex mobility assay (mHMA) to genotype homozygous mutants with small indels generated by CRISPR-Cas9 nucleases.

Foster SD, Glover SR, Turner AN, Chatti K, Challa AK.

MethodsX. 2018 Nov 27;6:1-5. doi: 10.1016/j.mex.2018.11.017. eCollection 2019.

5.

Truncating PKHD1 and PKD2 mutations alter energy metabolism.

Chumley P, Zhou J, Mrug S, Chacko B, Parant JM, Challa AK, Wilson LS, Berryhill TF, Barnes S, Kesterson RA, Bell PD, Darley-Usmar VM, Yoder BK, Mrug M.

Am J Physiol Renal Physiol. 2019 Mar 1;316(3):F414-F425. doi: 10.1152/ajprenal.00167.2018. Epub 2018 Dec 19.

PMID:
30566001
6.

Analysis of novel domain-specific mutations in the zebrafish ndr2/cyclops gene generated using CRISPR-Cas9 RNPs.

Turner AN, Andersen RS, Bookout IE, Brashear LN, Davis JC, Gahan DM, Davis JC, Gotham JP, Hijaz BA, Kaushik AS, Mcgill JB, Miller VL, Moseley ZP, Nowell CL, Patel RK, Rodgers MC, Patel RK, Shihab YA, Walker AP, Glover SR, Foster SD, Challa AK.

J Genet. 2018 Dec;97(5):1315-1325.

7.

NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer.

Dischinger PS, Tovar EA, Essenburg CJ, Madaj ZB, Gardner EE, Callaghan ME, Turner AN, Challa AK, Kempston T, Eagleson B, Kesterson RA, Bronson RT, Bowman MJ, Graveel CR, Steensma MR.

NPJ Breast Cancer. 2018 Aug 30;4:29. doi: 10.1038/s41523-018-0080-8. eCollection 2018.

8.

First Year Course-Based Undergraduate Research Experience (CURE) Using the CRISPR/Cas9 Genome Engineering Technology in Zebrafish.

Bhatt JM, Challa AK.

J Microbiol Biol Educ. 2017 Jan 29;19(1). pii: 19.1.3. doi: 10.1128/jmbe.v19i1.1245. eCollection 2018.

9.

Increased trabecular bone and improved biomechanics in an osteocalcin-null rat model created by CRISPR/Cas9 technology.

Lambert LJ, Challa AK, Niu A, Zhou L, Tucholski J, Johnson MS, Nagy TR, Eberhardt AW, Estep PN, Kesterson RA, Grams JM.

Dis Model Mech. 2016 Oct 1;9(10):1169-1179. Epub 2016 Jul 28.

10.

Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease.

Lewis WR, Malarkey EB, Tritschler D, Bower R, Pasek RC, Porath JD, Birket SE, Saunier S, Antignac C, Knowles MR, Leigh MW, Zariwala MA, Challa AK, Kesterson RA, Rowe SM, Drummond IA, Parant JM, Hildebrandt F, Porter ME, Yoder BK, Berbari NF.

PLoS Genet. 2016 Jul 29;12(7):e1006220. doi: 10.1371/journal.pgen.1006220. eCollection 2016 Jul.

11.

Novel Hypomorphic Alleles of the Mouse Tyrosinase Gene Induced by CRISPR-Cas9 Nucleases Cause Non-Albino Pigmentation Phenotypes.

Challa AK, Boitet ER, Turner AN, Johnson LW, Kennedy D, Downs ER, Hymel KM, Gross AK, Kesterson RA.

PLoS One. 2016 May 25;11(5):e0155812. doi: 10.1371/journal.pone.0155812. eCollection 2016.

12.

Conservation and early expression of zebrafish tyrosine kinases support the utility of zebrafish as a model for tyrosine kinase biology.

Challa AK, Chatti K.

Zebrafish. 2013 Sep;10(3):264-74. doi: 10.1089/zeb.2012.0781. Epub 2012 Dec 12.

13.

Caffeine-induced effects on heart rate in zebrafish embryos and possible mechanisms of action: an effective system for experiments in chemical biology.

Rana N, Moond M, Marthi A, Bapatla S, Sarvepalli T, Chatti K, Challa AK.

Zebrafish. 2010 Mar;7(1):69-81. doi: 10.1089/zeb.2009.0631.

PMID:
20415645
14.

9-O-acetylation of exogenously added ganglioside GD3. The GD3 molecule induces its own O-acetylation machinery.

Chen HY, Challa AK, Varki A.

J Biol Chem. 2006 Mar 24;281(12):7825-33. Epub 2006 Jan 24.

15.

Robo3 isoforms have distinct roles during zebrafish development.

Challa AK, McWhorter ML, Wang C, Seeger MA, Beattie CE.

Mech Dev. 2005 Oct;122(10):1073-86.

16.

Identification and characterization of roundabout orthologs in zebrafish.

Challa AK, Beattie CE, Seeger MA.

Mech Dev. 2001 Mar;101(1-2):249-53.

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