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Items: 1 to 50 of 119

1.

US national academies offer tools for human rights in science.

Chalfie M, Everly R.

Nature. 2019 Feb;566(7743):182. doi: 10.1038/d41586-019-00550-x. No abstract available.

PMID:
30755762
2.

Inhibition of cell fate repressors secures the differentiation of the touch receptor neurons of Caenorhabditis elegans.

Zheng C, Jin FQ, Trippe BL, Wu J, Chalfie M.

Development. 2018 Nov 15;145(22). pii: dev168096. doi: 10.1242/dev.168096.

PMID:
30291162
3.

Distinct effects of tubulin isotype mutations on neurite growth in Caenorhabditis elegans.

Zheng C, Diaz-Cuadros M, Nguyen KCQ, Hall DH, Chalfie M.

Mol Biol Cell. 2017 Oct 15;28(21):2786-2801. doi: 10.1091/mbc.E17-06-0424. Epub 2017 Aug 23. Erratum in: Mol Biol Cell. 2017 Dec 1;28(25):3724-3725.

4.

Regulation of the epithelial Na+ channel by paraoxonase-2.

Shi S, Buck TM, Kinlough CL, Marciszyn AL, Hughey RP, Chalfie M, Brodsky JL, Kleyman TR.

J Biol Chem. 2017 Sep 22;292(38):15927-15938. doi: 10.1074/jbc.M117.785253. Epub 2017 Aug 2.

5.

GEFs and Rac GTPases control directional specificity of neurite extension along the anterior-posterior axis.

Zheng C, Diaz-Cuadros M, Chalfie M.

Proc Natl Acad Sci U S A. 2016 Jun 21;113(25):6973-8. doi: 10.1073/pnas.1607179113. Epub 2016 Jun 6.

6.

SCIENTIFIC COMMUNITY. Preprints for the life sciences.

Berg JM, Bhalla N, Bourne PE, Chalfie M, Drubin DG, Fraser JS, Greider CW, Hendricks M, Jones C, Kiley R, King S, Kirschner MW, Krumholz HM, Lehmann R, Leptin M, Pulverer B, Rosenzweig B, Spiro JE, Stebbins M, Strasser C, Swaminathan S, Turner P, Vale RD, VijayRaghavan K, Wolberger C.

Science. 2016 May 20;352(6288):899-901. doi: 10.1126/science.aaf9133. No abstract available.

PMID:
27199406
7.

MEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans.

Chen Y, Bharill S, O'Hagan R, Isacoff EY, Chalfie M.

G3 (Bethesda). 2016 Apr 7;6(4):1121-30. doi: 10.1534/g3.115.023507.

8.

Securing Neuronal Cell Fate in C. elegans.

Zheng C, Chalfie M.

Curr Top Dev Biol. 2016;116:167-80. doi: 10.1016/bs.ctdb.2015.11.011. Epub 2016 Jan 23. Review.

PMID:
26970619
9.

Caenorhabditis elegans paraoxonase-like proteins control the functional expression of DEG/ENaC mechanosensory proteins.

Chen Y, Bharill S, Altun Z, O'Hagan R, Coblitz B, Isacoff EY, Chalfie M.

Mol Biol Cell. 2016 Apr 15;27(8):1272-85. doi: 10.1091/mbc.E15-08-0561. Epub 2016 Mar 3.

10.

Hox Proteins Act as Transcriptional Guarantors to Ensure Terminal Differentiation.

Zheng C, Jin FQ, Chalfie M.

Cell Rep. 2015 Nov 17;13(7):1343-1352. doi: 10.1016/j.celrep.2015.10.044. Epub 2015 Nov 4.

11.

Hox Genes Promote Neuronal Subtype Diversification through Posterior Induction in Caenorhabditis elegans.

Zheng C, Diaz-Cuadros M, Chalfie M.

Neuron. 2015 Nov 4;88(3):514-27. doi: 10.1016/j.neuron.2015.09.049.

12.

Dishevelled attenuates the repelling activity of Wnt signaling during neurite outgrowth in Caenorhabditis elegans.

Zheng C, Diaz-Cuadros M, Chalfie M.

Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13243-8. doi: 10.1073/pnas.1518686112. Epub 2015 Oct 12.

13.

Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans.

Chen Y, Bharill S, Isacoff EY, Chalfie M.

Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11690-5. doi: 10.1073/pnas.1515968112. Epub 2015 Aug 31.

14.

A Transparent Window into Biology: A Primer on Caenorhabditis elegans.

Corsi AK, Wightman B, Chalfie M.

Genetics. 2015 Jun;200(2):387-407. doi: 10.1534/genetics.115.176099. Erratum in: Genetics. 2015 Sep;201(1):339.

15.

A Transparent window into biology: A primer on Caenorhabditis elegans.

Corsi AK, Wightman B, Chalfie M.

WormBook. 2015 Jun 18:1-31. doi: 10.1895/wormbook.1.177.1. Review.

16.

FBN-1, a fibrillin-related protein, is required for resistance of the epidermis to mechanical deformation during C. elegans embryogenesis.

Kelley M, Yochem J, Krieg M, Calixto A, Heiman MG, Kuzmanov A, Meli V, Chalfie M, Goodman MB, Shaham S, Frand A, Fay DS.

Elife. 2015 Mar 23;4. doi: 10.7554/eLife.06565.

17.

Regulation of mechanosensation in C. elegans through ubiquitination of the MEC-4 mechanotransduction channel.

Chen X, Chalfie M.

J Neurosci. 2015 Feb 4;35(5):2200-12. doi: 10.1523/JNEUROSCI.4082-14.2015.

18.
19.

Assaying mechanosensation.

Chalfie M, Hart AC, Rankin CH, Goodman MB.

WormBook. 2014 Jul 31. doi: 10.1895/wormbook.1.172.1. Review.

20.

Modulation of C. elegans touch sensitivity is integrated at multiple levels.

Chen X, Chalfie M.

J Neurosci. 2014 May 7;34(19):6522-36. doi: 10.1523/JNEUROSCI.0022-14.2014.

21.

A disease-causing mutation illuminates the protein membrane topology of the kidney-expressed prohibitin homology (PHB) domain protein podocin.

Schurek EM, Völker LA, Tax J, Lamkemeyer T, Rinschen MM, Ungrue D, Kratz JE 3rd, Sirianant L, Kunzelmann K, Chalfie M, Schermer B, Benzing T, Höhne M.

J Biol Chem. 2014 Apr 18;289(16):11262-71. doi: 10.1074/jbc.M113.521773. Epub 2014 Mar 4.

22.

Histone methylation restrains the expression of subtype-specific genes during terminal neuronal differentiation in Caenorhabditis elegans.

Zheng C, Karimzadegan S, Chiang V, Chalfie M.

PLoS Genet. 2013;9(12):e1004017. doi: 10.1371/journal.pgen.1004017. Epub 2013 Dec 12.

23.

Chocolate habits of Nobel prizewinners.

Golomb BA, Brenner S, Chalfie M, Glashow SL, Glauber RJ, Hubel DH, Maskin ES, Greengard P, Gross DJ, Roberts R, Tonegawa S, Wilczek FA, Brown EM, Sejnowski TJ.

Nature. 2013 Jul 25;499(7459):409. doi: 10.1038/499409a. No abstract available.

24.

A combinatorial regulatory signature controls terminal differentiation of the dopaminergic nervous system in C. elegans.

Doitsidou M, Flames N, Topalidou I, Abe N, Felton T, Remesal L, Popovitchenko T, Mann R, Chalfie M, Hobert O.

Genes Dev. 2013 Jun 15;27(12):1391-405. doi: 10.1101/gad.217224.113.

25.

Being counted.

Chalfie M.

Angew Chem Int Ed Engl. 2013 Jan 2;52(1):74. doi: 10.1002/anie.201205223. Epub 2012 Dec 12. No abstract available.

PMID:
23239512
26.

Genetically separable functions of the MEC-17 tubulin acetyltransferase affect microtubule organization.

Topalidou I, Keller C, Kalebic N, Nguyen KC, Somhegyi H, Politi KA, Heppenstall P, Hall DH, Chalfie M.

Curr Biol. 2012 Jun 19;22(12):1057-65. doi: 10.1016/j.cub.2012.03.066. Epub 2012 May 31.

27.

Shared gene expression in distinct neurons expressing common selector genes.

Topalidou I, Chalfie M.

Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19258-63. doi: 10.1073/pnas.1111684108. Epub 2011 Nov 15.

28.

The DEG/ENaC protein MEC-10 regulates the transduction channel complex in Caenorhabditis elegans touch receptor neurons.

Arnadóttir J, O'Hagan R, Chen Y, Goodman MB, Chalfie M.

J Neurosci. 2011 Aug 31;31(35):12695-704. doi: 10.1523/JNEUROSCI.4580-10.2011.

29.

Microtubule depolymerization in Caenorhabditis elegans touch receptor neurons reduces gene expression through a p38 MAPK pathway.

Bounoutas A, Kratz J, Emtage L, Ma C, Nguyen KC, Chalfie M.

Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):3982-7. doi: 10.1073/pnas.1101360108. Epub 2011 Feb 22.

30.

Caenorhabditis elegans aristaless/Arx gene alr-1 restricts variable gene expression.

Topalidou I, van Oudenaarden A, Chalfie M.

Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4063-8. doi: 10.1073/pnas.1101329108. Epub 2011 Feb 22.

31.

Enhanced neuronal RNAi in C. elegans using SID-1.

Calixto A, Chelur D, Topalidou I, Chen X, Chalfie M.

Nat Methods. 2010 Jul;7(7):554-9. doi: 10.1038/nmeth.1463. Epub 2010 May 30.

32.

Conditional gene expression and RNAi using MEC-8-dependent splicing in C. elegans.

Calixto A, Ma C, Chalfie M.

Nat Methods. 2010 May;7(5):407-11. doi: 10.1038/nmeth.1445. Epub 2010 Apr 4.

33.

Eukaryotic mechanosensitive channels.

Arnadóttir J, Chalfie M.

Annu Rev Biophys. 2010;39:111-37. doi: 10.1146/annurev.biophys.37.032807.125836. Review.

PMID:
20192782
34.

The 2009 Lindau Nobel Laureate meeting: Martin Chalfie, Chemistry 2008.

Chalfie M.

J Vis Exp. 2010 Feb 10;(36). pii: 1570. doi: 10.3791/1570.

35.

Learning from students at Lindau.

Chalfie M.

Nat Chem. 2009 Nov;1(8):586-7. doi: 10.1038/nchem.375. No abstract available.

PMID:
21378941
36.

mec-15 encodes an F-box protein required for touch receptor neuron mechanosensation, synapse formation and development.

Bounoutas A, Zheng Q, Nonet ML, Chalfie M.

Genetics. 2009 Oct;183(2):607-17, 1SI-4SI. doi: 10.1534/genetics.109.105726. Epub 2009 Aug 3.

37.

The multipurpose 15-protofilament microtubules in C. elegans have specific roles in mechanosensation.

Bounoutas A, O'Hagan R, Chalfie M.

Curr Biol. 2009 Aug 25;19(16):1362-7. doi: 10.1016/j.cub.2009.06.036. Epub 2009 Jul 16.

38.

GFP: lighting up life (Nobel Lecture).

Chalfie M.

Angew Chem Int Ed Engl. 2009;48(31):5603-11. doi: 10.1002/anie.200902040. No abstract available.

PMID:
19569155
39.

GFP: Lighting up life.

Chalfie M.

Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10073-80. doi: 10.1073/pnas.0904061106. No abstract available.

40.

Neurosensory mechanotransduction.

Chalfie M.

Nat Rev Mol Cell Biol. 2009 Jan;10(1):44-52. doi: 10.1038/nrm2595. Review.

PMID:
19197331
41.

Touch sensitivity in Caenorhabditis elegans.

Bounoutas A, Chalfie M.

Pflugers Arch. 2007 Aug;454(5):691-702. Epub 2007 Feb 7. Review.

PMID:
17285303
42.

Targeted cell killing by reconstituted caspases.

Chelur DS, Chalfie M.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2283-8. Epub 2007 Feb 5. Erratum in: Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):824.

43.

WormBook: the online review of Caenorhabditis elegans biology.

Girard LR, Fiedler TJ, Harris TW, Carvalho F, Antoshechkin I, Han M, Sternberg PW, Stein LD, Chalfie M.

Nucleic Acids Res. 2007 Jan;35(Database issue):D472-5. Epub 2006 Nov 11.

44.

Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels.

Huber TB, Schermer B, Müller RU, Höhne M, Bartram M, Calixto A, Hagmann H, Reinhardt C, Koos F, Kunzelmann K, Shirokova E, Krautwurst D, Harteneck C, Simons M, Pavenstädt H, Kerjaschki D, Thiele C, Walz G, Chalfie M, Benzing T.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17079-86. Epub 2006 Nov 1.

45.

Loss of LIN-35, the Caenorhabditis elegans ortholog of the tumor suppressor p105Rb, results in enhanced RNA interference.

Lehner B, Calixto A, Crombie C, Tischler J, Fortunato A, Chalfie M, Fraser AG.

Genome Biol. 2006;7(1):R4. Epub 2006 Jan 20.

46.

Mechanosensation in Caenorhabditis elegans.

O'Hagan R, Chalfie M.

Int Rev Neurobiol. 2006;69:169-203. Review. No abstract available.

PMID:
16492465
47.

The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals.

O'Hagan R, Chalfie M, Goodman MB.

Nat Neurosci. 2005 Jan;8(1):43-50. Epub 2004 Dec 5.

PMID:
15580270
48.
49.

MEC-2 is recruited to the putative mechanosensory complex in C. elegans touch receptor neurons through its stomatin-like domain.

Zhang S, Arnadottir J, Keller C, Caldwell GA, Yao CA, Chalfie M.

Curr Biol. 2004 Nov 9;14(21):1888-96.

50.

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