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Items: 18

1.

Vaso-Occlusion in Sickle Cell Disease: Is Autonomic Dysregulation of the Microvasculature the Trigger?

Veluswamy S, Shah P, Denton CC, Chalacheva P, Khoo MCK, Coates TD.

J Clin Med. 2019 Oct 15;8(10). pii: E1690. doi: 10.3390/jcm8101690. Review.

2.

Erythrocyte and plasma oxidative stress appears to be compensated in patients with sickle cell disease during a period of relative health, despite the presence of known oxidative agents.

Detterich JA, Liu H, Suriany S, Kato RM, Chalacheva P, Tedla B, Shah PM, Khoo MC, Wood JC, Coates TD, Milne GL, Oh JY, Patel RP, Forman HJ.

Free Radic Biol Med. 2019 Sep;141:408-415. doi: 10.1016/j.freeradbiomed.2019.07.004. Epub 2019 Jul 3.

PMID:
31279092
3.

Respiratory modulation of peripheral vasoconstriction: a modeling perspective.

Khoo MCK, Chalacheva P.

J Appl Physiol (1985). 2019 Nov 1;127(5):1177-1186. doi: 10.1152/japplphysiol.00111.2019. Epub 2019 May 16.

PMID:
31095465
4.

Sickle Cell Disease Subjects Have a Distinct Abnormal Autonomic Phenotype Characterized by Peripheral Vasoconstriction With Blunted Cardiac Response to Head-Up Tilt.

Chalacheva P, Kato RM, Shah P, Veluswamy S, Denton CC, Sunwoo J, Thuptimdang W, Wood JC, Detterich JA, Coates TD, Khoo MCK.

Front Physiol. 2019 Apr 11;10:381. doi: 10.3389/fphys.2019.00381. eCollection 2019.

5.

Mental stress causes vasoconstriction in subjects with sickle cell disease and in normal controls.

Shah P, Khaleel M, Thuptimdang W, Sunwoo J, Veluswamy S, Chalacheva P, Kato RM, Detterich J, Wood JC, Zeltzer L, Sposto R, Khoo MCK, Coates TD.

Haematologica. 2020 Jan;105(1):83-90. doi: 10.3324/haematol.2018.211391. Epub 2019 Apr 11.

6.

Sickle cell microvascular paradox-oxygen supply-demand mismatch.

Detterich JA, Kato R, Bush A, Chalacheva P, Ponce D, De Zoysa M, Shah P, Khoo MC, Meiselman HJ, Coates TD, Wood JC.

Am J Hematol. 2019 Jun;94(6):678-688. doi: 10.1002/ajh.25476. Epub 2019 Apr 19.

PMID:
30916797
7.

A novel cross-correlation methodology for assessing biophysical responses associated with pain.

Sunwoo J, Chalacheva P, Khaleel M, Shah P, Sposto R, Kato RM, Detterich J, Zeltzer LK, Wood JC, Coates TD, Khoo MC.

J Pain Res. 2018 Oct 5;11:2207-2219. doi: 10.2147/JPR.S142582. eCollection 2018.

8.

Autonomic nervous system involvement in sickle cell disease.

Coates TD, Chalacheva P, Zeltzer L, Khoo MCK.

Clin Hemorheol Microcirc. 2018;68(2-3):251-262. doi: 10.3233/CH-189011.

PMID:
29614636
9.

Individuals with sickle cell disease have a significantly greater vasoconstriction response to thermal pain than controls and have significant vasoconstriction in response to anticipation of pain.

Khaleel M, Puliyel M, Shah P, Sunwoo J, Kato RM, Chalacheva P, Thuptimdang W, Detterich J, Wood JC, Tsao J, Zeltzer L, Sposto R, Khoo MCK, Coates TD.

Am J Hematol. 2017 Nov;92(11):1137-1145. doi: 10.1002/ajh.24858. Epub 2017 Aug 17.

10.

Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease.

Chalacheva P, Khaleel M, Sunwoo J, Shah P, Detterich JA, Kato RM, Thuptimdang W, Meiselman HJ, Sposto R, Tsao J, Wood JC, Zeltzer L, Coates TD, Khoo MCK.

PLoS One. 2017 May 24;12(5):e0178353. doi: 10.1371/journal.pone.0178353. eCollection 2017.

11.

Model-Derived Markers of Autonomic Cardiovascular Dysfunction in Sleep-Disordered Breathing.

Khoo MCK, Chalacheva P.

Sleep Med Clin. 2016 Dec;11(4):489-501. doi: 10.1016/j.jsmc.2016.07.003. Epub 2016 Oct 27. Review.

12.

Model-based stability assessment of ventilatory control in overweight adolescents with obstructive sleep apnea during NREM sleep.

Nava-Guerra L, Tran WH, Chalacheva P, Loloyan S, Joshi B, Keens TG, Nayak KS, Davidson Ward SL, Khoo MC.

J Appl Physiol (1985). 2016 Jul 1;121(1):185-97. doi: 10.1152/japplphysiol.01081.2015. Epub 2016 May 12.

13.

Modeling of deep breath vasoconstriction reflex.

Chalacheva P, Khoo MC.

Conf Proc IEEE Eng Med Biol Soc. 2015;2015:7792-5. doi: 10.1109/EMBC.2015.7320199.

14.

Autonomic responses to cold face stimulation in sickle cell disease: a time-varying model analysis.

Chalacheva P, Kato RM, Sangkatumvong S, Detterich J, Bush A, Wood JC, Meiselman H, Coates TD, Khoo MC.

Physiol Rep. 2015 Jul 14;3(7). pii: e12463. doi: 10.14814/phy2.12463. Epub 2015 Jul 14.

15.

Estimating the baroreflex and respiratory modulation of peripheral vascular resistance.

Chalacheva P, Khoo MC.

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:2936-9. doi: 10.1109/EMBC.2014.6944238.

16.

An extended model of blood pressure variability: incorporating the respiratory modulation of vascular resistance.

Chalacheva P, Khoo MC.

Conf Proc IEEE Eng Med Biol Soc. 2013;2013:3825-8. doi: 10.1109/EMBC.2013.6610378.

PMID:
24110565
17.

Development of autonomic dysfunction with intermittent hypoxia in a lean murine model.

Chalacheva P, Thum J, Yokoe T, O'Donnell CP, Khoo MC.

Respir Physiol Neurobiol. 2013 Aug 15;188(2):143-51. doi: 10.1016/j.resp.2013.06.002. Epub 2013 Jun 14.

18.

Monitoring ultradian changes in cardiorespiratory control in obstructive sleep apnea syndrome.

Khoo MC, Wang W, Chalacheva P.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:1487-90. doi: 10.1109/IEMBS.2011.6090363.

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