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Items: 1 to 50 of 155

1.

Inducible gene switches with memory in human T cells for cellular immunotherapy.

Chakravarti D, Caraballo LD, Weinberg B, Wong W.

ACS Synth Biol. 2019 Jul 3. doi: 10.1021/acssynbio.8b00512. [Epub ahead of print]

PMID:
31268301
2.

Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor.

Adhikary S, Chakravarti D, Terranova C, Sengupta I, Maitituoheti M, Dasgupta A, Srivastava DK, Ma J, Raman AT, Tarco E, Sahin AA, Bassett R, Yang F, Tapia C, Roy S, Rai K, Das C.

Nat Commun. 2019 Mar 28;10(1):1398. doi: 10.1038/s41467-019-08986-5.

3.

KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer.

Liao W, Overman MJ, Boutin AT, Shang X, Zhao D, Dey P, Li J, Wang G, Lan Z, Li J, Tang M, Jiang S, Ma X, Chen P, Katkhuda R, Korphaisarn K, Chakravarti D, Chang A, Spring DJ, Chang Q, Zhang J, Maru DM, Maeda DY, Zebala JA, Kopetz S, Wang YA, DePinho RA.

Cancer Cell. 2019 Apr 15;35(4):559-572.e7. doi: 10.1016/j.ccell.2019.02.008. Epub 2019 Mar 21.

PMID:
30905761
4.

Application of ex-vivo spheroid model system for the analysis of senescence and senolytic phenotypes in uterine leiomyoma.

Xie J, Xu X, Yin P, Li Y, Guo H, Kujawa S, Chakravarti D, Bulun S, Kim JJ, Wei JJ.

Lab Invest. 2018 Dec;98(12):1575-1587. doi: 10.1038/s41374-018-0117-5. Epub 2018 Sep 11.

5.

Comparative analysis of AKT and the related biomarkers in uterine leiomyomas with MED12, HMGA2, and FH mutations.

Xie J, Ubango J, Ban Y, Chakravarti D, Kim JJ, Wei JJ.

Genes Chromosomes Cancer. 2018 Oct;57(10):485-494. doi: 10.1002/gcc.22643. Epub 2018 Aug 20.

PMID:
29790226
6.

The AKT/BCL-2 Axis Mediates Survival of Uterine Leiomyoma in a Novel 3D Spheroid Model.

Vidimar V, Chakravarti D, Bulun SE, Yin P, Nowak R, Wei JJ, Kim JJ.

Endocrinology. 2018 Mar 1;159(3):1453-1462. doi: 10.1210/en.2017-03191.

7.

Feeling Stressed under the Sun? RPA1 Acetylation to the Rescue.

Chakravarti D, Hazra TK.

Cell Rep. 2017 Aug 29;20(9):1995-1996. doi: 10.1016/j.celrep.2017.08.045.

8.

Protein Tyrosine Nitration: Role in Aging.

Chakravarti B, Chakravarti DN.

Curr Aging Sci. 2017;10(4):246-262. doi: 10.2174/1874609810666170315112634. Review.

PMID:
28302048
9.

Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer.

Zhao D, Lu X, Wang G, Lan Z, Liao W, Li J, Liang X, Chen JR, Shah S, Shang X, Tang M, Deng P, Dey P, Chakravarti D, Chen P, Spring DJ, Navone NM, Troncoso P, Zhang J, Wang YA, DePinho RA.

Nature. 2017 Feb 23;542(7642):484-488. doi: 10.1038/nature21357. Epub 2017 Feb 6.

10.

Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas.

Vidimar V, Gius D, Chakravarti D, Bulun SE, Wei JJ, Kim JJ.

Sci Adv. 2016 Nov 4;2(11):e1601132. eCollection 2016 Nov.

11.

KAT8 Regulates Androgen Signaling in Prostate Cancer Cells.

Kim JY, Yu J, Abdulkadir SA, Chakravarti D.

Mol Endocrinol. 2016 Aug;30(8):925-36. doi: 10.1210/me.2016-1024. Epub 2016 Jun 7.

12.

Decreased expression of microRNA-29 family in leiomyoma contributes to increased major fibrillar collagen production.

Marsh EE, Steinberg ML, Parker JB, Wu J, Chakravarti D, Bulun SE.

Fertil Steril. 2016 Sep 1;106(3):766-72. doi: 10.1016/j.fertnstert.2016.05.001. Epub 2016 May 24.

13.

Pancreatic proteome profiling of type 1 diabetic mouse: Differential expression of proteins involved in exocrine function, stress response, growth, apoptosis and metabolism.

Chakravarti B, Sherpa C, Bose D, Paul Chowdhury K, Khadar K, Zhang YC, Chakravarti DN.

Biochem Biophys Res Commun. 2017 Jun 10;487(4):930-936. doi: 10.1016/j.bbrc.2016.04.121. Epub 2016 Apr 25.

PMID:
27125462
14.

Synthetic biology approaches in cancer immunotherapy, genetic network engineering, and genome editing.

Chakravarti D, Cho JH, Weinberg BH, Wong NM, Wong WW.

Integr Biol (Camb). 2016 Apr 18;8(4):504-17. doi: 10.1039/c5ib00325c. Epub 2016 Apr 12. Review.

PMID:
27068224
15.

Genomic Determinants of THAP11/ZNF143/HCFC1 Complex Recruitment to Chromatin.

Vinckevicius A, Parker JB, Chakravarti D.

Mol Cell Biol. 2015 Dec;35(24):4135-46. doi: 10.1128/MCB.00477-15. Epub 2015 Sep 28.

16.

LncRNA HOTAIR Enhances the Androgen-Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer.

Zhang A, Zhao JC, Kim J, Fong KW, Yang YA, Chakravarti D, Mo YY, Yu J.

Cell Rep. 2015 Oct 6;13(1):209-221. doi: 10.1016/j.celrep.2015.08.069. Epub 2015 Sep 24.

17.

Uterine Leiomyoma Stem Cells: Linking Progesterone to Growth.

Bulun SE, Moravek MB, Yin P, Ono M, Coon JS 5th, Dyson MT, Navarro A, Marsh EE, Zhao H, Maruyama T, Chakravarti D, Kim JJ, Wei JJ.

Semin Reprod Med. 2015 Sep;33(5):357-65. doi: 10.1055/s-0035-1558451. Epub 2015 Aug 6. Review.

PMID:
26251118
18.

Synthetic biology in cell-based cancer immunotherapy.

Chakravarti D, Wong WW.

Trends Biotechnol. 2015 Aug;33(8):449-61. doi: 10.1016/j.tibtech.2015.05.001. Epub 2015 Jun 16. Review.

19.

Human uterine leiomyoma stem/progenitor cells expressing CD34 and CD49b initiate tumors in vivo.

Yin P, Ono M, Moravek MB, Coon JS 5th, Navarro A, Monsivais D, Dyson MT, Druschitz SA, Malpani SS, Serna VA, Qiang W, Chakravarti D, Kim JJ, Bulun SE.

J Clin Endocrinol Metab. 2015 Apr;100(4):E601-6. doi: 10.1210/jc.2014-2134. Epub 2015 Feb 6.

20.

Host cell factor-1 recruitment to E2F-bound and cell-cycle-control genes is mediated by THAP11 and ZNF143.

Parker JB, Yin H, Vinckevicius A, Chakravarti D.

Cell Rep. 2014 Nov 6;9(3):967-82. doi: 10.1016/j.celrep.2014.09.051. Epub 2014 Oct 30.

21.

IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo.

Venkatanarayan A, Raulji P, Norton W, Chakravarti D, Coarfa C, Su X, Sandur SK, Ramirez MS, Lee J, Kingsley CV, Sananikone EF, Rajapakshe K, Naff K, Parker-Thornburg J, Bankson JA, Tsai KY, Gunaratne PH, Flores ER.

Nature. 2015 Jan 29;517(7536):626-30. doi: 10.1038/nature13910. Epub 2014 Nov 17.

22.

Ovarian steroids, stem cells and uterine leiomyoma: therapeutic implications.

Moravek MB, Yin P, Ono M, Coon JS 5th, Dyson MT, Navarro A, Marsh EE, Chakravarti D, Kim JJ, Wei JJ, Bulun SE.

Hum Reprod Update. 2015 Jan-Feb;21(1):1-12. doi: 10.1093/humupd/dmu048. Epub 2014 Sep 8. Review.

23.

A role for WDR5 in integrating threonine 11 phosphorylation to lysine 4 methylation on histone H3 during androgen signaling and in prostate cancer.

Kim JY, Banerjee T, Vinckevicius A, Luo Q, Parker JB, Baker MR, Radhakrishnan I, Wei JJ, Barish GD, Chakravarti D.

Mol Cell. 2014 May 22;54(4):613-25. doi: 10.1016/j.molcel.2014.03.043. Epub 2014 May 1. Erratum in: Mol Cell. 2015 May 7;58(3):557.

24.

Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8.

Chakravarti D, Su X, Cho MS, Bui NH, Coarfa C, Venkatanarayan A, Benham AL, Flores González RE, Alana J, Xiao W, Leung ML, Vin H, Chan IL, Aquino A, Müller N, Wang H, Cooney AJ, Parker-Thornburg J, Tsai KY, Gunaratne PH, Flores ER.

Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):E572-81. doi: 10.1073/pnas.1319743111. Epub 2014 Jan 21.

25.

BRAF inhibitors suppress apoptosis through off-target inhibition of JNK signaling.

Vin H, Ojeda SS, Ching G, Leung ML, Chitsazzadeh V, Dwyer DW, Adelmann CH, Restrepo M, Richards KN, Stewart LR, Du L, Ferguson SB, Chakravarti D, Ehrenreiter K, Baccarini M, Ruggieri R, Curry JL, Kim KB, Ciurea AM, Duvic M, Prieto VG, Ullrich SE, Dalby KN, Flores ER, Tsai KY.

Elife. 2013 Nov 5;2:e00969. doi: 10.7554/eLife.00969.

26.

Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth.

Ono M, Yin P, Navarro A, Moravek MB, Coon JS 5th, Druschitz SA, Serna VA, Qiang W, Brooks DC, Malpani SS, Ma J, Ercan CM, Mittal N, Monsivais D, Dyson MT, Yemelyanov A, Maruyama T, Chakravarti D, Kim JJ, Kurita T, Gottardi CJ, Bulun SE.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17053-8. doi: 10.1073/pnas.1313650110. Epub 2013 Sep 30.

27.

MK-2206, an AKT inhibitor, promotes caspase-independent cell death and inhibits leiomyoma growth.

Sefton EC, Qiang W, Serna V, Kurita T, Wei JJ, Chakravarti D, Kim JJ.

Endocrinology. 2013 Nov;154(11):4046-57. doi: 10.1210/en.2013-1389. Epub 2013 Sep 3.

28.

Ligand-activated peroxisome proliferator-activated receptor β/δ modulates human endometrial cancer cell survival.

Ma JJ, Monsivais D, Dyson MT, Coon JS, Malpani S, Ono M, Zhao H, Xin H, Pavone ME, Kim JJ, Chakravarti D, Bulun SE.

Horm Cancer. 2013 Dec;4(6):358-70. doi: 10.1007/s12672-013-0157-7. Epub 2013 Aug 14.

29.

Expression profiling of nuclear receptors identifies key roles of NR4A subfamily in uterine fibroids.

Yin H, Lo JH, Kim JY, Marsh EE, Kim JJ, Ghosh AK, Bulun S, Chakravarti D.

Mol Endocrinol. 2013 May;27(5):726-40. doi: 10.1210/me.2012-1305. Epub 2013 Apr 2.

30.

p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis.

Su X, Chakravarti D, Flores ER.

Nat Rev Cancer. 2013 Feb;13(2):136-43. doi: 10.1038/nrc3446. Review.

31.

Differential hepatic protein tyrosine nitration of mouse due to aging - effect on mitochondrial energy metabolism, quality control machinery of the endoplasmic reticulum and metabolism of drugs.

Marshall A, Lutfeali R, Raval A, Chakravarti DN, Chakravarti B.

Biochem Biophys Res Commun. 2013 Jan 4;430(1):231-5. doi: 10.1016/j.bbrc.2012.10.142. Epub 2012 Nov 15.

PMID:
23159622
32.

TAp63 is a master transcriptional regulator of lipid and glucose metabolism.

Su X, Gi YJ, Chakravarti D, Chan IL, Zhang A, Xia X, Tsai KY, Flores ER.

Cell Metab. 2012 Oct 3;16(4):511-25. doi: 10.1016/j.cmet.2012.09.006.

33.

Chromatin immunoprecipitation: advancing analysis of nuclear hormone signaling.

Vinckevicius A, Chakravarti D.

J Mol Endocrinol. 2012 Sep 5;49(2):R113-23. doi: 10.1530/JME-12-0016. Print 2012 Oct. Review.

34.

ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression.

Ahn YH, Gibbons DL, Chakravarti D, Creighton CJ, Rizvi ZH, Adams HP, Pertsemlidis A, Gregory PA, Wright JA, Goodall GJ, Flores ER, Kurie JM.

J Clin Invest. 2012 Sep;122(9):3170-83. doi: 10.1172/JCI63608. Epub 2012 Aug 1.

35.

KDM3B is the H3K9 demethylase involved in transcriptional activation of lmo2 in leukemia.

Kim JY, Kim KB, Eom GH, Choe N, Kee HJ, Son HJ, Oh ST, Kim DW, Pak JH, Baek HJ, Kook H, Hahn Y, Kook H, Chakravarti D, Seo SB.

Mol Cell Biol. 2012 Jul;32(14):2917-33. doi: 10.1128/MCB.00133-12. Epub 2012 May 21.

36.

A transcriptional regulatory role of the THAP11-HCF-1 complex in colon cancer cell function.

Parker JB, Palchaudhuri S, Yin H, Wei J, Chakravarti D.

Mol Cell Biol. 2012 May;32(9):1654-70. doi: 10.1128/MCB.06033-11. Epub 2012 Feb 27.

37.

A peek into the complex realm of histone phosphorylation.

Banerjee T, Chakravarti D.

Mol Cell Biol. 2011 Dec;31(24):4858-73. doi: 10.1128/MCB.05631-11. Epub 2011 Oct 17. Review.

38.

Inhibition of p53 acetylation by INHAT subunit SET/TAF-Iβ represses p53 activity.

Kim JY, Lee KS, Seol JE, Yu K, Chakravarti D, Seo SB.

Nucleic Acids Res. 2012 Jan;40(1):75-87. doi: 10.1093/nar/gkr614. Epub 2011 Sep 12.

39.

SPATA18, a spermatogenesis-associated gene, is a novel transcriptional target of p53 and p63.

Bornstein C, Brosh R, Molchadsky A, Madar S, Kogan-Sakin I, Goldstein I, Chakravarti D, Flores ER, Goldfinger N, Sarig R, Rotter V.

Mol Cell Biol. 2011 Apr;31(8):1679-89. doi: 10.1128/MCB.01072-10. Epub 2011 Feb 7.

40.

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

Su X, Chakravarti D, Cho MS, Liu L, Gi YJ, Lin YL, Leung ML, El-Naggar A, Creighton CJ, Suraokar MB, Wistuba I, Flores ER.

Nature. 2010 Oct 21;467(7318):986-90. doi: 10.1038/nature09459.

41.

Proteomics and systems biology: application in drug discovery and development.

Chakravarti B, Mallik B, Chakravarti DN.

Methods Mol Biol. 2010;662:3-28. doi: 10.1007/978-1-60761-800-3_1. Review.

PMID:
20824464
42.

Transcription factor KLF11 integrates progesterone receptor signaling and proliferation in uterine leiomyoma cells.

Yin P, Lin Z, Reierstad S, Wu J, Ishikawa H, Marsh EE, Innes J, Cheng Y, Pearson K, Coon JS 5th, Kim JJ, Chakravarti D, Bulun SE.

Cancer Res. 2010 Feb 15;70(4):1722-30. doi: 10.1158/0008-5472.CAN-09-2612. Epub 2010 Feb 2.

43.

Comparison of SYPRO Ruby and Flamingo fluorescent stains for application in proteomic research.

Chakravarti B, Fathy P, Sindicich M, Mallik B, Chakravarti DN.

Anal Biochem. 2010 Mar 1;398(1):1-6. doi: 10.1016/j.ab.2009.07.055. Epub 2009 Nov 14.

PMID:
19917264
44.

Glucocorticoid-stimulated, transcription-independent release of annexin A1 by cochlear Hensen cells.

Kalinec F, Webster P, Maricle A, Guerrero D, Chakravarti DN, Chakravarti B, Gellibolian R, Kalinec G.

Br J Pharmacol. 2009 Dec;158(7):1820-34. doi: 10.1111/j.1476-5381.2009.00473.x.

45.

NAD(P)H:quinone oxidoreductase 1 Arg139Trp and Pro187Ser polymorphisms imbalance estrogen metabolism towards DNA adduct formation in human mammary epithelial cells.

Singh S, Zahid M, Saeed M, Gaikwad NW, Meza JL, Cavalieri EL, Rogan EG, Chakravarti D.

J Steroid Biochem Mol Biol. 2009 Oct;117(1-3):56-66. doi: 10.1016/j.jsbmb.2009.07.003. Epub 2009 Jul 21.

46.

Depurinating naphthalene-DNA adducts in mouse skin related to cancer initiation.

Saeed M, Higginbotham S, Gaikwad N, Chakravarti D, Rogan E, Cavalieri E.

Free Radic Biol Med. 2009 Oct 1;47(7):1075-81. doi: 10.1016/j.freeradbiomed.2009.07.020. Epub 2009 Jul 18.

47.

Identifying hubs in protein interaction networks.

Vallabhajosyula RR, Chakravarti D, Lutfeali S, Ray A, Raval A.

PLoS One. 2009;4(4):e5344. doi: 10.1371/journal.pone.0005344. Epub 2009 Apr 28.

48.

Chromatin binding of SRp20 and ASF/SF2 and dissociation from mitotic chromosomes is modulated by histone H3 serine 10 phosphorylation.

Loomis RJ, Naoe Y, Parker JB, Savic V, Bozovsky MR, Macfarlan T, Manley JL, Chakravarti D.

Mol Cell. 2009 Feb 27;33(4):450-61. doi: 10.1016/j.molcel.2009.02.003.

49.

Progestins activate the AKT pathway in leiomyoma cells and promote survival.

Hoekstra AV, Sefton EC, Berry E, Lu Z, Hardt J, Marsh E, Yin P, Clardy J, Chakravarti D, Bulun S, Kim JJ.

J Clin Endocrinol Metab. 2009 May;94(5):1768-74. doi: 10.1210/jc.2008-2093. Epub 2009 Feb 24.

50.

Proteome profiling of aging in mouse models: differential expression of proteins involved in metabolism, transport, and stress response in kidney.

Chakravarti B, Seshi B, Ratanaprayul W, Dalal N, Lin L, Raval A, Chakravarti DN.

Proteomics. 2009 Feb;9(3):580-97. doi: 10.1002/pmic.200700208.

PMID:
19184973

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