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Items: 1 to 50 of 56


Molecular mechanism of setron-mediated inhibition of full-length 5-HT3A receptor.

Basak S, Gicheru Y, Kapoor A, Mayer ML, Filizola M, Chakrapani S.

Nat Commun. 2019 Jul 19;10(1):3225. doi: 10.1038/s41467-019-11142-8.


Multiscale model to study dislocation dynamics in nonlinear resonance spectroscopy of crystalline solids.

Chakrapani SK.

Ultrasonics. 2019 Jul;96:220-223. doi: 10.1016/j.ultras.2019.01.003. Epub 2019 Jan 16.


Low-field 1H-NMR spectroscopy for compositional analysis of multicomponent polymer systems.

Chakrapani SB, Minkler MJ, Beckingham BS.

Analyst. 2019 Feb 25;144(5):1679-1686. doi: 10.1039/c8an01810c.


Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3A receptor.

Basak S, Gicheru Y, Rao S, Sansom MSP, Chakrapani S.

Nature. 2018 Nov;563(7730):270-274. doi: 10.1038/s41586-018-0660-7. Epub 2018 Oct 31.


Direct visualization of ion-channel gating in a native environment.

Gicheru Y, Chakrapani S.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10198-10200. doi: 10.1073/pnas.1814277115. Epub 2018 Sep 26. No abstract available.


The voltage-gated sodium channel pore exhibits conformational flexibility during slow inactivation.

Chatterjee S, Vyas R, Chalamalasetti SV, Sahu ID, Clatot J, Wan X, Lorigan GA, Deschênes I, Chakrapani S.

J Gen Physiol. 2018 Sep 3;150(9):1333-1347. doi: 10.1085/jgp.201812118. Epub 2018 Aug 6.


Cryo-EM structure of 5-HT3A receptor in its resting conformation.

Basak S, Gicheru Y, Samanta A, Molugu SK, Huang W, Fuente M, Hughes T, Taylor DJ, Nieman MT, Moiseenkova-Bell V, Chakrapani S.

Nat Commun. 2018 Feb 6;9(1):514. doi: 10.1038/s41467-018-02997-4.


Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.

Hughes TET, Lodowski DT, Huynh KW, Yazici A, Del Rosario J, Kapoor A, Basak S, Samanta A, Han X, Chakrapani S, Zhou ZH, Filizola M, Rohacs T, Han S, Moiseenkova-Bell VY.

Nat Struct Mol Biol. 2018 Jan;25(1):53-60. doi: 10.1038/s41594-017-0009-1. Epub 2018 Jan 1.


Influence of surface roughness on the measurement of acoustic nonlinearity parameter of solids using contact piezoelectric transducers.

Chakrapani SK, Howard A, Barnard D.

Ultrasonics. 2018 Mar;84:112-118. doi: 10.1016/j.ultras.2017.10.022. Epub 2017 Oct 28.


Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel.

Basak S, Schmandt N, Gicheru Y, Chakrapani S.

Elife. 2017 Mar 6;6. pii: e23886. doi: 10.7554/eLife.23886.


Determination of acoustic nonlinearity parameter (β) using nonlinear resonance ultrasound spectroscopy: Theory and experiment.

Chakrapani SK, Barnard DJ.

J Acoust Soc Am. 2017 Feb;141(2):919. doi: 10.1121/1.4976057.


Numerical study of Rayleigh wave propagation along a horizontal semi-infinite crack buried in half-space.

Chakrapani SK.

J Acoust Soc Am. 2017 Jan;141(1):137. doi: 10.1121/1.4973688.


Photoinduced Homolytic Bond Cleavage of the Central Si-C Bond in Porphyrin Macrocycles Is a Charge Polarization Driven Process.

Maiti B, Manna AK, McCleese C, Doane TL, Chakrapani S, Burda C, Dunietz BD.

J Phys Chem A. 2016 Oct 6;120(39):7634-7640. Epub 2016 Sep 21.


VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.

Guo X, Sun X, Hu D, Wang YJ, Fujioka H, Vyas R, Chakrapani S, Joshi AU, Luo Y, Mochly-Rosen D, Qi X.

Nat Commun. 2016 Aug 26;7:12646. doi: 10.1038/ncomms12646.


Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels.

Basak S, Chatterjee S, Chakrapani S.

J Vis Exp. 2016 Jul 4;(113). doi: 10.3791/54127.


Influence of laminate sequence and fabric type on the inherent acoustic nonlinearity in carbon fiber reinforced composites.

Chakrapani SK, Barnard DJ, Dayal V.

J Acoust Soc Am. 2016 May;139(5):2310. doi: 10.1121/1.4946996.


Preclinical to Clinical Translation of Antibody-Drug Conjugates Using PK/PD Modeling: a Retrospective Analysis of Inotuzumab Ozogamicin.

Betts AM, Haddish-Berhane N, Tolsma J, Jasper P, King LE, Sun Y, Chakrapani S, Shor B, Boni J, Johnson TR.

AAPS J. 2016 Sep;18(5):1101-16. doi: 10.1208/s12248-016-9929-7. Epub 2016 May 19.


A chimeric prokaryotic pentameric ligand-gated channel reveals distinct pathways of activation.

Schmandt N, Velisetty P, Chalamalasetti SV, Stein RA, Bonner R, Talley L, Parker MD, Mchaourab HS, Yee VC, Lodowski DT, Chakrapani S.

J Gen Physiol. 2015 Oct;146(4):323-40. doi: 10.1085/jgp.201511478.


Voxel Based Morphometry Alterations in Mal de Debarquement Syndrome.

Cha YH, Chakrapani S.

PLoS One. 2015 Aug 7;10(8):e0135021. doi: 10.1371/journal.pone.0135021. eCollection 2015.


Finite element simulation of core inspection in helicopter rotor blades using guided waves.

Chakrapani SK, Barnard D, Dayal V.

Ultrasonics. 2015 Sep;62:126-35. doi: 10.1016/j.ultras.2015.05.009. Epub 2015 May 23.


EPR Studies of Gating Mechanisms in Ion Channels.

Chakrapani S.

Methods Enzymol. 2015;557:279-306. doi: 10.1016/bs.mie.2014.12.030. Epub 2015 Mar 24. Review.


Local delivery of hyaluronan 0.8% as an adjunct to scaling and root planing in the treatment of chronic periodontitis: A clinical and microbiological study.

Polepalle T, Srinivas M, Swamy N, Aluru S, Chakrapani S, Chowdary BA.

J Indian Soc Periodontol. 2015 Jan-Feb;19(1):37-42. doi: 10.4103/0972-124X.145807.


Influence of fiber orientation on the inherent acoustic nonlinearity in carbon fiber reinforced composites.

Chakrapani SK, Barnard DJ, Dayal V.

J Acoust Soc Am. 2015 Feb;137(2):617-24. doi: 10.1121/1.4906165.


Periotest values: Its reproducibility, accuracy, and variability with hormonal influence.

Chakrapani S, Goutham M, Krishnamohan T, Anuparthy S, Tadiboina N, Rambha S.

Contemp Clin Dent. 2015 Jan-Mar;6(1):12-5. doi: 10.4103/0976-237X.149284.


Transforming growth factor receptor type II (ec-TβR II) behaves as a halophile.

Saini K, Khan MA, Chakrapani S, Deep S.

Int J Biol Macromol. 2015 Jan;72:1104-10.


Anthropometrics of mental foramen in dry dentate and edentulous mandibles in Coastal Andhra population of Andhra Pradesh State.

Moogala S, Sanivarapu S, Boyapati R, Devulapalli NS, Chakrapani S, Kolaparthy L.

J Indian Soc Periodontol. 2014 Jul;18(4):497-502. doi: 10.4103/0972-124X.138715.


The interaction of Rayleigh waves with delaminations in composite laminates.

Chakrapani SK, Dayal V.

J Acoust Soc Am. 2014 May;135(5):2646-53. doi: 10.1121/1.4869684.


Choice of diagnostic and therapeutic imaging in periodontics and implantology.

Chakrapani S, Sirisha K, Srilalitha A, Srinivas M.

J Indian Soc Periodontol. 2013 Nov;17(6):711-8. doi: 10.4103/0972-124X.124474. Review.


Structural insight into the assembly of TRPV channels.

Huynh KW, Cohen MR, Chakrapani S, Holdaway HA, Stewart PL, Moiseenkova-Bell VY.

Structure. 2014 Feb 4;22(2):260-8. doi: 10.1016/j.str.2013.11.008. Epub 2013 Dec 26.


Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC).

Velisetty P, Chalamalasetti SV, Chakrapani S.

J Biol Chem. 2014 Jan 31;289(5):3013-25. doi: 10.1074/jbc.M113.523050. Epub 2013 Dec 13.


Nondestructive evaluation of helicopter rotor blades using guided Lamb modes.

Chakrapani SK, Barnard D, Dayal V.

Ultrasonics. 2014 Mar;54(3):826-33. doi: 10.1016/j.ultras.2013.10.011. Epub 2013 Oct 24.


Regional correlation between resting state FDG PET and pCASL perfusion MRI.

Cha YH, Jog MA, Kim YC, Chakrapani S, Kraman SM, Wang DJ.

J Cereb Blood Flow Metab. 2013 Dec;33(12):1909-14. doi: 10.1038/jcbfm.2013.147. Epub 2013 Aug 21.


Ligand-protein interactions of selective casein kinase 1δ inhibitors.

Mente S, Arnold E, Butler T, Chakrapani S, Chandrasekaran R, Cherry K, DiRico K, Doran A, Fisher K, Galatsis P, Green M, Hayward M, Humphrey J, Knafels J, Li J, Liu S, Marconi M, McDonald S, Ohren J, Paradis V, Sneed B, Walton K, Wager T.

J Med Chem. 2013 Sep 12;56(17):6819-28. doi: 10.1021/jm4006324. Epub 2013 Aug 28.


Recovery from slow inactivation in K+ channels is controlled by water molecules.

Ostmeyer J, Chakrapani S, Pan AC, Perozo E, Roux B.

Nature. 2013 Sep 5;501(7465):121-4. doi: 10.1038/nature12395. Epub 2013 Jul 28.


Chairside quantitative immunochromatographic evaluation of salivary cotinine and its correlation with chronic periodontitis.

Surya C, Swamy DN, Chakrapani S, Kumar SS.

J Indian Soc Periodontol. 2012 Oct;16(4):508-12. doi: 10.4103/0972-124X.106888.


Metabolic and functional connectivity changes in mal de debarquement syndrome.

Cha YH, Chakrapani S, Craig A, Baloh RW.

PLoS One. 2012;7(11):e49560. doi: 10.1371/journal.pone.0049560. Epub 2012 Nov 29.


Conformational transitions underlying pore opening and desensitization in membrane-embedded Gloeobacter violaceus ligand-gated ion channel (GLIC).

Velisetty P, Chalamalasetti SV, Chakrapani S.

J Biol Chem. 2012 Oct 26;287(44):36864-72. doi: 10.1074/jbc.M112.401067. Epub 2012 Sep 13.


Desensitization mechanism in prokaryotic ligand-gated ion channel.

Velisetty P, Chakrapani S.

J Biol Chem. 2012 May 25;287(22):18467-77. doi: 10.1074/jbc.M112.348045. Epub 2012 Apr 3.


Short-term plasticity of gray matter associated with leptin deficiency and replacement.

London ED, Berman SM, Chakrapani S, Delibasi T, Monterosso J, Erol HK, Paz-Filho G, Wong ML, Licinio J.

J Clin Endocrinol Metab. 2011 Aug;96(8):E1212-20. doi: 10.1210/jc.2011-0314. Epub 2011 May 25. Erratum in: J Clin Endocrinol Metab. 2011 Nov;96(11):3576. Dosage error in article text.


A multipoint hydrogen-bond network underlying KcsA C-type inactivation.

Cordero-Morales JF, Jogini V, Chakrapani S, Perozo E.

Biophys J. 2011 May 18;100(10):2387-93. doi: 10.1016/j.bpj.2011.01.073.


Different forms of self-control share a neurocognitive substrate.

Tabibnia G, Monterosso JR, Baicy K, Aron AR, Poldrack RA, Chakrapani S, Lee B, London ED.

J Neurosci. 2011 Mar 30;31(13):4805-10. doi: 10.1523/JNEUROSCI.2859-10.2011.


On the structural basis of modal gating behavior in K(+) channels.

Chakrapani S, Cordero-Morales JF, Jogini V, Pan AC, Cortes DM, Roux B, Perozo E.

Nat Struct Mol Biol. 2011 Jan;18(1):67-74. doi: 10.1038/nsmb.1968. Epub 2010 Dec 26.


Neuroimaging study designs, computational analyses and data provenance using the LONI pipeline.

Dinov I, Lozev K, Petrosyan P, Liu Z, Eggert P, Pierce J, Zamanyan A, Chakrapani S, Van Horn J, Parker DS, Magsipoc R, Leung K, Gutman B, Woods R, Toga A.

PLoS One. 2010 Sep 28;5(9). pii: e13070. doi: 10.1371/journal.pone.0013070.


Cortical sulcal atlas construction using a diffeomorphic mapping approach.

Joshi SH, Cabeen RP, Sun B, Joshi AA, Gutman B, Zamanyan A, Chakrapani S, Dinov I, Woods RP, Toga AW.

Med Image Comput Comput Assist Interv. 2010;13(Pt 1):357-66.


Structural basis for the coupling between activation and inactivation gates in K(+) channels.

Cuello LG, Jogini V, Cortes DM, Pan AC, Gagnon DG, Dalmas O, Cordero-Morales JF, Chakrapani S, Roux B, Perozo E.

Nature. 2010 Jul 8;466(7303):272-5. doi: 10.1038/nature09136.


The activated state of a sodium channel voltage sensor in a membrane environment.

Chakrapani S, Sompornpisut P, Intharathep P, Roux B, Perozo E.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5435-40. doi: 10.1073/pnas.0914109107. Epub 2010 Mar 5.


Osteoblastoma of the spine with discordant magnetic resonance imaging and computed tomography imaging features in a child.

Chakrapani SD, Grim K, Kaimaktchiev V, Anderson JC.

Spine (Phila Pa 1976). 2008 Dec 1;33(25):E968-70. doi: 10.1097/BRS.0b013e31818a0271.


Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer.

Chakrapani S, Cuello LG, Cortes DM, Perozo E.

Structure. 2008 Mar;16(3):398-409. doi: 10.1016/j.str.2007.12.015.


A quantitative description of KcsA gating II: single-channel currents.

Chakrapani S, Cordero-Morales JF, Perozo E.

J Gen Physiol. 2007 Nov;130(5):479-96. Epub 2007 Oct 15.


A quantitative description of KcsA gating I: macroscopic currents.

Chakrapani S, Cordero-Morales JF, Perozo E.

J Gen Physiol. 2007 Nov;130(5):465-78. Epub 2007 Oct 15.

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