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Items: 9


Nitric oxide induced S-nitrosation causes base excision repair imbalance.

Parrish MC, Chaim IA, Nagel ZD, Tannenbaum SR, Samson LD, Engelward BP.

DNA Repair (Amst). 2018 Aug;68:25-33. doi: 10.1016/j.dnarep.2018.04.008. Epub 2018 May 5.


In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities.

Chaim IA, Nagel ZD, Jordan JJ, Mazzucato P, Ngo LP, Samson LD.

Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10379-E10388. doi: 10.1073/pnas.1712032114. Epub 2017 Nov 9.


Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms.

Margulies CM, Chaim IA, Mazumder A, Criscione J, Samson LD.

PLoS One. 2017 Sep 8;12(9):e0184619. doi: 10.1371/journal.pone.0184619. eCollection 2017.


Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9.

Batra R, Nelles DA, Pirie E, Blue SM, Marina RJ, Wang H, Chaim IA, Thomas JD, Zhang N, Nguyen V, Aigner S, Markmiller S, Xia G, Corbett KD, Swanson MS, Yeo GW.

Cell. 2017 Aug 24;170(5):899-912.e10. doi: 10.1016/j.cell.2017.07.010. Epub 2017 Aug 10.


A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine.

Chaim IA, Gardner A, Wu J, Iyama T, Wilson DM 3rd, Samson LD.

Nucleic Acids Res. 2017 Apr 7;45(6):3242-3252. doi: 10.1093/nar/gkx015.


DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme.

Nagel ZD, Kitange GJ, Gupta SK, Joughin BA, Chaim IA, Mazzucato P, Lauffenburger DA, Sarkaria JN, Samson LD.

Cancer Res. 2017 Jan 1;77(1):198-206. doi: 10.1158/0008-5472.CAN-16-1151. Epub 2016 Oct 28.


Inter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair research.

Nagel ZD, Chaim IA, Samson LD.

DNA Repair (Amst). 2014 Jul;19:199-213. doi: 10.1016/j.dnarep.2014.03.009. Epub 2014 Apr 26.


Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis.

Nagel ZD, Margulies CM, Chaim IA, McRee SK, Mazzucato P, Ahmad A, Abo RP, Butty VL, Forget AL, Samson LD.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1823-32. doi: 10.1073/pnas.1401182111. Epub 2014 Apr 22.


Evaluation of the potential of novel PCL-PPDX biodegradable scaffolds as support materials for cartilage tissue engineering.

Chaim IA, Sabino MA, Mendt M, Müller AJ, Ajami D.

J Tissue Eng Regen Med. 2012 Apr;6(4):272-9. doi: 10.1002/term.430. Epub 2011 May 5.


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